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The map label for this gene is PE_PGRS36

Identifier: 121637983

GI number: 121637983

Start: 2338184

End: 2339659

Strand: Reverse

Name: PE_PGRS36

Synonym: BCG_2118c

Alternate gene names: 121637983

Gene position: 2339659-2338184 (Counterclockwise)

Preceding gene: 121637987

Following gene: 121637982

Centisome position: 53.48

GC content: 75.27

Gene sequence:

>1476_bases
ATGTCGTTTGTGATTGCGAGCCCGGAGGCATTGCTGGCTGCGGCCACGGATTTAGCGGCCATCCGTTCGACCATCAGGGC
AGCGAACGCGGCGGCGGCGGTCCCGACGACGGGGGCGTTGGCGCCCGCCGCCGATGAGGTGTCGGCGGGCATAGCGGCGC
TATTTGGCGCCCAGGCCCAGAGCTATCAAGCGGTCAGCGCCCAGGCGGCGGCGTTTCATGACCGGTTCGTCCAACTGCTT
AACGCCGGTGGAGGTTCATATGCGAGCGCCGAGATTGCCAACGCGCAGCAGAACCTGCTGAACGCGGTGAACGCGCCCAC
CCAGACGCTGCTGGGGCGTCCGCTGGTCGGCGACGGCGCCGACGGGGCCAGTGGTCCGGTGGGACAGCCCGGCGGGGACG
GCGGCATCTTGTGGGGCAACGGCGGCAACGGTGGCGACAGCACGAGCCCCGGGGTTGCCGGGGGAGCCGGCGGGTCAGCG
GGGCTGATCGGCAACGGCGGCAGGGGCGGCAACGGTGCGCCCGGCGGTGCAGGAGGCAATGGCGGCCTGGGCGGATTGCT
GCTGGGCAACGGGGGTGCCGGGGGAGTCGGCGGTACCGGTGACAACGGTGTGGGAGACCTCGGTGCTGGCGGCGGGGGAG
GCGATGGCGGTTTGGGTGGACGGGCGGGGCTGATCGGTCACGGCGGTGCCGGCGGAAACGGTGGGGACGGTGGGCACGGC
GGGAGCGGCAAGGCCGGCGGCAGTGGCGGCAGTGGCGGCTTCGGCCAGTTCGGTGGCGCCGGCGGGCTGCTGTACGGCAA
TGGAGGGGCGGCCGGTTCCGGCGGCAACGGTGGCGATGCAGGTACCGGCGTCTCCAGCGACGGTTTCGCCGGGTTGGGCG
GCAGCGGTGGCCGGGGCGGCGACGCGGGGCTGATTGGTGTCGGCGGCGGCGGCGGCAACGGCGGCGACCCAGGGCTCGGT
GCGCGCCTGTTCCAGGTAGGTAGTCGCGGCGGCGACGGTGGGGTCGGCGGGTGGCTGTACGGCGATGGCGGCGGCGGCGG
CGACGGCGGTAATGGGGGGCTGCCATTTATTGGCTCCACCAACGCCGGCAACGGCGGCAGCGCGCGGCTCATCGGCAACG
GTGGTGCCGGCGGTAGCGGCGGGAGCGGCGCGCCTGGCTCGGTCAGCAGCGGTGGCGTCGGGGGCGCGGGCAACCCCGGC
GGCAGCGGTGGCAACGGCGGCGTGTGGTACGGCAACGGTGGCGCCGGCGGGGCCGCCGGCCAAGGGGGGCCCGGCATGAA
CACCACCTCGCCCGGCGGGCCGGGCGGTGTCGGCGGGCACGGCGGCACCGCCATCTTGTTCGGCGACGGTGGCGCCGGTG
GGGCTGGCGCCGCCGGCGGACCCGGTACTCCGGACGGGGCCGCGGGGCCCGGCGGCAGCGGCGGCACCGGCGGGCTGCTG
TTCGGAGTCCCCGGCCCGTCCGGCCCGGACGGGTAA

Upstream 100 bases:

>100_bases
CACCCCGACTGAGGGTGGGGGATCGCAATACGATATTCCTGCCATACGCATCGACGGTTCCGGCGCAGCCGGGTTATCGC
GGGTTGGTGGGAGGTGCGCA

Downstream 100 bases:

>100_bases
CGGGCGTGGCTATCGCGCCGCCGCCAACCAACAACCAGTACCCTCAAATACGTGCAGCGTCGAATCATGGGCATCGAAAC
CGAGTTCGGTGTCACCTGCA

Product: PE-PGRS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MSFVIASPEALLAAATDLAAIRSTIRAANAAAAVPTTGALAPAADEVSAGIAALFGAQAQSYQAVSAQAAAFHDRFVQLL
NAGGGSYASAEIANAQQNLLNAVNAPTQTLLGRPLVGDGADGASGPVGQPGGDGGILWGNGGNGGDSTSPGVAGGAGGSA
GLIGNGGRGGNGAPGGAGGNGGLGGLLLGNGGAGGVGGTGDNGVGDLGAGGGGGDGGLGGRAGLIGHGGAGGNGGDGGHG
GSGKAGGSGGSGGFGQFGGAGGLLYGNGGAAGSGGNGGDAGTGVSSDGFAGLGGSGGRGGDAGLIGVGGGGGNGGDPGLG
ARLFQVGSRGGDGGVGGWLYGDGGGGGDGGNGGLPFIGSTNAGNGGSARLIGNGGAGGSGGSGAPGSVSSGGVGGAGNPG
GSGGNGGVWYGNGGAGGAAGQGGPGMNTTSPGGPGGVGGHGGTAILFGDGGAGGAGAAGGPGTPDGAAGPGGSGGTGGLL
FGVPGPSGPDG

Sequences:

>Translated_491_residues
MSFVIASPEALLAAATDLAAIRSTIRAANAAAAVPTTGALAPAADEVSAGIAALFGAQAQSYQAVSAQAAAFHDRFVQLL
NAGGGSYASAEIANAQQNLLNAVNAPTQTLLGRPLVGDGADGASGPVGQPGGDGGILWGNGGNGGDSTSPGVAGGAGGSA
GLIGNGGRGGNGAPGGAGGNGGLGGLLLGNGGAGGVGGTGDNGVGDLGAGGGGGDGGLGGRAGLIGHGGAGGNGGDGGHG
GSGKAGGSGGSGGFGQFGGAGGLLYGNGGAAGSGGNGGDAGTGVSSDGFAGLGGSGGRGGDAGLIGVGGGGGNGGDPGLG
ARLFQVGSRGGDGGVGGWLYGDGGGGGDGGNGGLPFIGSTNAGNGGSARLIGNGGAGGSGGSGAPGSVSSGGVGGAGNPG
GSGGNGGVWYGNGGAGGAAGQGGPGMNTTSPGGPGGVGGHGGTAILFGDGGAGGAGAAGGPGTPDGAAGPGGSGGTGGLL
FGVPGPSGPDG
>Mature_490_residues
SFVIASPEALLAAATDLAAIRSTIRAANAAAAVPTTGALAPAADEVSAGIAALFGAQAQSYQAVSAQAAAFHDRFVQLLN
AGGGSYASAEIANAQQNLLNAVNAPTQTLLGRPLVGDGADGASGPVGQPGGDGGILWGNGGNGGDSTSPGVAGGAGGSAG
LIGNGGRGGNGAPGGAGGNGGLGGLLLGNGGAGGVGGTGDNGVGDLGAGGGGGDGGLGGRAGLIGHGGAGGNGGDGGHGG
SGKAGGSGGSGGFGQFGGAGGLLYGNGGAAGSGGNGGDAGTGVSSDGFAGLGGSGGRGGDAGLIGVGGGGGNGGDPGLGA
RLFQVGSRGGDGGVGGWLYGDGGGGGDGGNGGLPFIGSTNAGNGGSARLIGNGGAGGSGGSGAPGSVSSGGVGGAGNPGG
SGGNGGVWYGNGGAGGAAGQGGPGMNTTSPGGPGGVGGHGGTAILFGDGGAGGAGAAGGPGTPDGAAGPGGSGGTGGLLF
GVPGPSGPDG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family. PGRS subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PG36_MYCBO (P0A689)

Other databases:

- EMBL:   BX248341
- RefSeq:   NP_855774.1
- EnsemblBacteria:   EBMYCT00000017204
- GeneID:   1091150
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2125c
- GeneTree:   EBGT00070000031715
- HOGENOM:   HBG127997
- OMA:   DHTVESS
- ProtClustDB:   CLSK799872
- BioCyc:   MBOV233413:MB2125C-MONOMER
- InterPro:   IPR000084

Pfam domain/function: PF00934 PE

EC number: NA

Molecular weight: Translated: 41979; Mature: 41848

Theoretical pI: Translated: 4.16; Mature: 4.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFVIASPEALLAAATDLAAIRSTIRAANAAAAVPTTGALAPAADEVSAGIAALFGAQAQ
CCEEECCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCHH
SYQAVSAQAAAFHDRFVQLLNAGGGSYASAEIANAQQNLLNAVNAPTQTLLGRPLVGDGA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCC
DGASGPVGQPGGDGGILWGNGGNGGDSTSPGVAGGAGGSAGLIGNGGRGGNGAPGGAGGN
CCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCC
GGLGGLLLGNGGAGGVGGTGDNGVGDLGAGGGGGDGGLGGRAGLIGHGGAGGNGGDGGHG
CCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCC
GSGKAGGSGGSGGFGQFGGAGGLLYGNGGAAGSGGNGGDAGTGVSSDGFAGLGGSGGRGG
CCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DAGLIGVGGGGGNGGDPGLGARLFQVGSRGGDGGVGGWLYGDGGGGGDGGNGGLPFIGST
CCCEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEECC
NAGNGGSARLIGNGGAGGSGGSGAPGSVSSGGVGGAGNPGGSGGNGGVWYGNGGAGGAAG
CCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCC
QGGPGMNTTSPGGPGGVGGHGGTAILFGDGGAGGAGAAGGPGTPDGAAGPGGSGGTGGLL
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
FGVPGPSGPDG
EECCCCCCCCC
>Mature Secondary Structure 
SFVIASPEALLAAATDLAAIRSTIRAANAAAAVPTTGALAPAADEVSAGIAALFGAQAQ
CEEECCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCHH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EECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972