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The map label for this gene is 121637875

Identifier: 121637875

GI number: 121637875

Start: 2212960

End: 2213304

Strand: Reverse

Name: 121637875

Synonym: BCG_2008c

Alternate gene names: NA

Gene position: 2213304-2212960 (Counterclockwise)

Preceding gene: 121637876

Following gene: 121637874

Centisome position: 50.6

GC content: 61.74

Gene sequence:

>345_bases
GTGGTGATTAGTCGTGCCGAGATCTACTGGGCTGACCTCGGGCCGCCATCAGGCAGTCAGCCGGCGAAGCGCCGCCCGGT
GCTCGTAATCCAGTCAGATCCGTACAACGCAAGTCGCCTTGCCACTGTGATCGCAGCGGTGATCACGTCCAATACGGCGC
TGGCGGCAATGCCCGGCAACGTGTTCTTGCCCGCGACCACAACGCGACTGCCACGTGACTCGGTCGTCAACGTCACGGCG
ATTGTCACGCTCAACAAGACTGACCTCACCGACCGAGTTGGGGAGGTGCCAGCGAGCTTGATGCACGAGGTTGACCGAGG
ACTTCGTCGCGTACTGGACCTTTGA

Upstream 100 bases:

>100_bases
GCCAGATCGACAGGGCTCTAGAGAGCATCCATGGCACCGACGAAGCGGAGGCCCTCGCCGTGGCCAACGCATACCGCGTG
CTAGAAACCATGGACGATGA

Downstream 100 bases:

>100_bases
CACTGCGCCACGCGACAATTCGTCACGGTGACGTTCCTGCTTGGTGTAAGCCCCCCCGCCGGGGGAACTACTCGCCGGAG
GTGGTGTTGTGGGCAGGCTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MVISRAEIYWADLGPPSGSQPAKRRPVLVIQSDPYNASRLATVIAAVITSNTALAAMPGNVFLPATTTRLPRDSVVNVTA
IVTLNKTDLTDRVGEVPASLMHEVDRGLRRVLDL

Sequences:

>Translated_114_residues
MVISRAEIYWADLGPPSGSQPAKRRPVLVIQSDPYNASRLATVIAAVITSNTALAAMPGNVFLPATTTRLPRDSVVNVTA
IVTLNKTDLTDRVGEVPASLMHEVDRGLRRVLDL
>Mature_114_residues
MVISRAEIYWADLGPPSGSQPAKRRPVLVIQSDPYNASRLATVIAAVITSNTALAAMPGNVFLPATTTRLPRDSVVNVTA
IVTLNKTDLTDRVGEVPASLMHEVDRGLRRVLDL

Specific function: Unknown

COG id: COG2337

COG function: function code T; Growth inhibitor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PemK/MazF family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1991_MYCTU (P64911)

Other databases:

- EMBL:   BX842578
- EMBL:   AE000516
- PIR:   E70757
- RefSeq:   NP_216507.1
- RefSeq:   NP_336509.1
- ProteinModelPortal:   P64911
- SMR:   P64911
- EnsemblBacteria:   EBMYCT00000002319
- EnsemblBacteria:   EBMYCT00000071461
- GeneID:   885634
- GeneID:   923421
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2046
- KEGG:   mtu:Rv1991c
- TIGR:   MT2046
- TubercuList:   Rv1991c
- GeneTree:   EBGT00050000018343
- HOGENOM:   HBG571026
- OMA:   LHRASEP
- ProtClustDB:   CLSK791544
- InterPro:   IPR003477
- InterPro:   IPR011067
- Gene3D:   G3DSA:2.30.30.110

Pfam domain/function: PF02452 PemK; SSF50118 Plasmid_toxin

EC number: NA

Molecular weight: Translated: 12262; Mature: 12262

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVISRAEIYWADLGPPSGSQPAKRRPVLVIQSDPYNASRLATVIAAVITSNTALAAMPGN
CCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCC
VFLPATTTRLPRDSVVNVTAIVTLNKTDLTDRVGEVPASLMHEVDRGLRRVLDL
EEECCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVISRAEIYWADLGPPSGSQPAKRRPVLVIQSDPYNASRLATVIAAVITSNTALAAMPGN
CCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCC
VFLPATTTRLPRDSVVNVTAIVTLNKTDLTDRVGEVPASLMHEVDRGLRRVLDL
EEECCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036