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The map label for this gene is modB

Identifier: 121637761

GI number: 121637761

Start: 2106731

End: 2107525

Strand: Direct

Name: modB

Synonym: BCG_1894

Alternate gene names: 121637761

Gene position: 2106731-2107525 (Clockwise)

Preceding gene: 121637760

Following gene: 121637762

Centisome position: 48.16

GC content: 66.54

Gene sequence:

>795_bases
ATGCACCCGCCTACGGATCTGCCTCGTTGGGTATATCTCCCGGCGATCGCGGGGATCGTGTTCGTGGCAATGCCGCTGGT
CGCGATCGCCATCCGGGTCGATTGGCCGCGTTTCTGGGCGCTGATCACTACTCCGTCTTCTCAAACGGCCCTGCTGTTGA
GCGTGAAGACCGCCGCGGCCAGCACGGTGCTGTGCGTACTGCTGGGCGTCCCGATGGCGCTGGTGCTGGCCCGCAGCCGC
GGACGACTGGTGCGGTCGTTACGACCGCTGATCCTGTTACCGCTGGTGCTGCCGCCGGTAGTCGGGGGTATCGCGTTGCT
CTACGCGTTCGGCCGGCTCGGCCTGATCGGGCGCTACCTGGAGGCGGCCGGCATCAGCATCGCATTCAGTACCGCGGCTG
TGGTGCTGGCGCAGACCTTTGTCTCGCTGCCGTATCTGGTGATTTCCCTAGAGGGTGCAGCCCGCACCGCCGGAGCCGAC
TACGAGGTGGTGGCGGCGACACTTGGGGCGCGGCCCGGCACTGTCTGGTGGCGCGTGACCCTGCCGTTGCTGCTCCCGGG
CGTGGTGTCCGGATCAGTACTGGCGTTTGCCCGCTCGCTCGGAGAGTTTGGCGCGACCCTAACCTTTGCCGGTTCCCGGC
AAGGGGTCACCCGTACCCTTCCGCTGGAGATTTACCTGCAGCGGGTGACCGATCCGGACGCGGCGGTGGCATTGTCACTG
CTGCTCGTTGTGGTAGCGGCACTGGTGGTGCTGGGTGTGGGTGCTCGTACGCCGATCGGGACCGATACCAGGTAG

Upstream 100 bases:

>100_bases
GGACCTCCCAGCCCGCTCTGGCCCGGCAGTTCGTGGCCATGGTGACCGCTGCGGCAGGTCGGCGGATCCTGGATCAGTCG
GGTTTCGCCAAGCCCTGACG

Downstream 100 bases:

>100_bases
CCGGTCATGAGCAAGCTGCAGCTGCGCGCGGTCGTCGCCGACCGGCGTTTGGACGTCGAATTCTCGGTGTCCGCGGGCGA
GGTGCTTGCAGTGCTCGGGC

Product: putative molbdenum-transport integral membrane protein ABC transporter modB

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MHPPTDLPRWVYLPAIAGIVFVAMPLVAIAIRVDWPRFWALITTPSSQTALLLSVKTAAASTVLCVLLGVPMALVLARSR
GRLVRSLRPLILLPLVLPPVVGGIALLYAFGRLGLIGRYLEAAGISIAFSTAAVVLAQTFVSLPYLVISLEGAARTAGAD
YEVVAATLGARPGTVWWRVTLPLLLPGVVSGSVLAFARSLGEFGATLTFAGSRQGVTRTLPLEIYLQRVTDPDAAVALSL
LLVVVAALVVLGVGARTPIGTDTR

Sequences:

>Translated_264_residues
MHPPTDLPRWVYLPAIAGIVFVAMPLVAIAIRVDWPRFWALITTPSSQTALLLSVKTAAASTVLCVLLGVPMALVLARSR
GRLVRSLRPLILLPLVLPPVVGGIALLYAFGRLGLIGRYLEAAGISIAFSTAAVVLAQTFVSLPYLVISLEGAARTAGAD
YEVVAATLGARPGTVWWRVTLPLLLPGVVSGSVLAFARSLGEFGATLTFAGSRQGVTRTLPLEIYLQRVTDPDAAVALSL
LLVVVAALVVLGVGARTPIGTDTR
>Mature_264_residues
MHPPTDLPRWVYLPAIAGIVFVAMPLVAIAIRVDWPRFWALITTPSSQTALLLSVKTAAASTVLCVLLGVPMALVLARSR
GRLVRSLRPLILLPLVLPPVVGGIALLYAFGRLGLIGRYLEAAGISIAFSTAAVVLAQTFVSLPYLVISLEGAARTAGAD
YEVVAATLGARPGTVWWRVTLPLLLPGVVSGSVLAFARSLGEFGATLTFAGSRQGVTRTLPLEIYLQRVTDPDAAVALSL
LLVVVAALVVLGVGARTPIGTDTR

Specific function: Part of the binding-protein-dependent transport system modABCD for molybdenum; probably responsible for the translocation of the substrate across the membrane

COG id: COG4149

COG function: function code P; ABC-type molybdate transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1788764, Length=214, Percent_Identity=32.2429906542056, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786980, Length=186, Percent_Identity=43.010752688172, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI87082099, Length=185, Percent_Identity=31.8918918918919, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1787080, Length=246, Percent_Identity=26.8292682926829, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787369, Length=216, Percent_Identity=25, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MODB_MYCBO (P0A625)

Other databases:

- EMBL:   BX248340
- RefSeq:   NP_855541.1
- ProteinModelPortal:   P0A625
- SMR:   P0A625
- EnsemblBacteria:   EBMYCT00000014584
- GeneID:   1093015
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1889
- GeneTree:   EBGT00050000015066
- HOGENOM:   HBG685300
- OMA:   LAWRGIL
- ProtClustDB:   CLSK871975
- BioCyc:   MBOV233413:MB1889-MONOMER
- InterPro:   IPR000515
- InterPro:   IPR011867
- InterPro:   IPR006469
- TIGRFAMs:   TIGR01581
- TIGRFAMs:   TIGR02141

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 27676; Mature: 27676

Theoretical pI: Translated: 11.15; Mature: 11.15

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x15f61108)-; HASH(0x167994b4)-; HASH(0x16828ef0)-; HASH(0x1662e344)-; HASH(0x15d6b294)-; HASH(0x163a1c74)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPPTDLPRWVYLPAIAGIVFVAMPLVAIAIRVDWPRFWALITTPSSQTALLLSVKTAAA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCHHEEEEEECCCCCEEEEEEEHHHHH
STVLCVLLGVPMALVLARSRGRLVRSLRPLILLPLVLPPVVGGIALLYAFGRLGLIGRYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAAGISIAFSTAAVVLAQTFVSLPYLVISLEGAARTAGADYEVVAATLGARPGTVWWRVT
HHCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCCEEEEEE
LPLLLPGVVSGSVLAFARSLGEFGATLTFAGSRQGVTRTLPLEIYLQRVTDPDAAVALSL
HHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEECHHHHHHHHCCCCHHHHHHHH
LLVVVAALVVLGVGARTPIGTDTR
HHHHHHHHHHHCCCCCCCCCCCCH
>Mature Secondary Structure
MHPPTDLPRWVYLPAIAGIVFVAMPLVAIAIRVDWPRFWALITTPSSQTALLLSVKTAAA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCHHEEEEEECCCCCEEEEEEEHHHHH
STVLCVLLGVPMALVLARSRGRLVRSLRPLILLPLVLPPVVGGIALLYAFGRLGLIGRYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAAGISIAFSTAAVVLAQTFVSLPYLVISLEGAARTAGADYEVVAATLGARPGTVWWRVT
HHCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCCEEEEEE
LPLLLPGVVSGSVLAFARSLGEFGATLTFAGSRQGVTRTLPLEIYLQRVTDPDAAVALSL
HHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEECHHHHHHHHCCCCHHHHHHHH
LLVVVAALVVLGVGARTPIGTDTR
HHHHHHHHHHHCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972