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The map label for this gene is 121637737

Identifier: 121637737

GI number: 121637737

Start: 2080785

End: 2081651

Strand: Direct

Name: 121637737

Synonym: BCG_1869

Alternate gene names: NA

Gene position: 2080785-2081651 (Clockwise)

Preceding gene: 121637735

Following gene: 121637750

Centisome position: 47.57

GC content: 66.09

Gene sequence:

>867_bases
GTGACATCACCGAGTGTCCGGGAGTGGCGTGACGGTGGCCGCTGGCTGCCGACGGCTGTCGGAAAGGTGTTCGTCCGGTC
GGGGCCGGGCGACACGCCAACAATGCTCCTGCTGCATGGCTATCCGTCCAGTTCGTTCGACTTCCGGGCGGTGATTCCAC
ACCTGACCGGCCAGGCTTGGGTAACGATGGATTTTCTGGGCTTTGGCTTGTCCGACAAGCCGCGCCCGCACCGGTACAGC
CTGCTGGAGCAGGCCCACCTGGTGGAAACGGTGGTCGCCCACACCGTGACCGGCGCGGTCGTCGTGCTGGCCCACGACAT
GGGCACGTCGGTGACCACCGAGCTGCTAGCCCGTGATTTGGACGGCCGGTTGCCGTTCGATCTCCGACGTGCGGTGCTGA
GCAACGGCAGTGTGATCTTGGAGCGGGCCAGCCTGCGTCCGATCCAGAAAGTACTGCGCAGCCCGCTTGGTCCGGTCGCT
GCCCGGCTGGTCAGCCGCGGTGGCTTCACACGAGGGTTTGGCCGGATCTTCTCCCCAGCGCACCCGCTGTCGGCGCAGGA
GGCCCAAGCCCAGTGGGAGTTGCTGTGCTACAACGACGGCAACCGGATCCCGCACCTGCTGATCAGCTACCTCGACGAGC
GGATACGGCACGCGCAGCGCTGGCATGGCGCGGTCCGCGATTGGCCCAAACCGCTTGGGTTCGTGTGGGGACTCGACGAT
CCGGTGGCAACAACCAACGTGCTCAATGGACTACGGGAATTGCGCCCCAGCGCCGCCGTCGTGGAACTGCCAGGGTTGGG
CCACTACCCGCAGGTCGAGGCTCCCAAAGCATATGCCGAGGCCGCGCTATCGCTGCTCGTCGACTAG

Upstream 100 bases:

>100_bases
GTCGAACCAGCGCGACTCGAACGGGTACAGCTGCGGATCCGGCGTGAAATCGATGCTCATTACCCTCCTCCGATCGCGCT
CATGATGGTATGCCCGAAGG

Downstream 100 bases:

>100_bases
CCGGCTACGGCTGTATCACGGGCAGATCGATGCGAGAGGCATGCATCCGGCTACGGTAGACGCGCACGGTCGGTGCGCAA
CCGGGAAGGATGGCGAAGTG

Product: putative hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAWVTMDFLGFGLSDKPRPHRYS
LLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDLDGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVA
ARLVSRGGFTRGFGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD
PVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLVD

Sequences:

>Translated_288_residues
MTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAWVTMDFLGFGLSDKPRPHRYS
LLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDLDGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVA
ARLVSRGGFTRGFGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD
PVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLVD
>Mature_287_residues
TSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAWVTMDFLGFGLSDKPRPHRYSL
LEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDLDGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAA
RLVSRGGFTRGFGRIFSPAHPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDDP
VATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLVD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily

Homologues:

Organism=Homo sapiens, GI29294637, Length=298, Percent_Identity=32.8859060402685, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI29294635, Length=298, Percent_Identity=32.8859060402685, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI29294639, Length=298, Percent_Identity=32.8859060402685, Blast_Score=148, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1834_MYCTU (Q50599)

Other databases:

- EMBL:   BX842578
- EMBL:   AE000516
- PIR:   C70722
- RefSeq:   NP_216350.1
- RefSeq:   NP_336340.1
- ProteinModelPortal:   Q50599
- EnsemblBacteria:   EBMYCT00000001818
- EnsemblBacteria:   EBMYCT00000070582
- GeneID:   888761
- GeneID:   923740
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1882
- KEGG:   mtu:Rv1834
- TIGR:   MT1882
- TubercuList:   Rv1834
- GeneTree:   EBGT00050000015244
- HOGENOM:   HBG748003
- OMA:   YRFKQNR
- ProtClustDB:   CLSK867982
- InterPro:   IPR000073
- InterPro:   IPR000639
- PRINTS:   PR00412

Pfam domain/function: PF00561 Abhydrolase_1

EC number: NA

Molecular weight: Translated: 31677; Mature: 31546

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW
CCCCCCHHHHCCCCCCHHHHHHHEEECCCCCCCEEEEEECCCCCCCCCEECCCCCCCCCE
VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL
EEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHC
DGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPA
CCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHCCCC
HPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD
CCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCC
PVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLVD
CHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TSPSVREWRDGGRWLPTAVGKVFVRSGPGDTPTMLLLHGYPSSSFDFRAVIPHLTGQAW
CCCCCHHHHCCCCCCHHHHHHHEEECCCCCCCEEEEEECCCCCCCCCEECCCCCCCCCE
VTMDFLGFGLSDKPRPHRYSLLEQAHLVETVVAHTVTGAVVVLAHDMGTSVTTELLARDL
EEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHC
DGRLPFDLRRAVLSNGSVILERASLRPIQKVLRSPLGPVAARLVSRGGFTRGFGRIFSPA
CCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHCCCC
HPLSAQEAQAQWELLCYNDGNRIPHLLISYLDERIRHAQRWHGAVRDWPKPLGFVWGLDD
CCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCC
PVATTNVLNGLRELRPSAAVVELPGLGHYPQVEAPKAYAEAALSLLVD
CHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036