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The map label for this gene is 121637731

Identifier: 121637731

GI number: 121637731

Start: 2074092

End: 2074835

Strand: Direct

Name: 121637731

Synonym: BCG_1863

Alternate gene names: NA

Gene position: 2074092-2074835 (Clockwise)

Preceding gene: 121637730

Following gene: 121637732

Centisome position: 47.41

GC content: 65.73

Gene sequence:

>744_bases
GTGAGCGCACCCGATAGCCCCGCGCTGGCCGGGATGTCGATCGGGGCGGTCCTCGACCTGCTACGACCGGATTTTCCTGA
TGTCACCATCTCCAAGATTCGATTCTTGGAGGCTGAGGGTCTGGTGACGCCCCGGCGGGCCTCATCGGGGTATCGGCGGT
TCACCGCATACGACTGCGCACGGCTGCGATTCATTCTCACTGCCCAGAGGGACCATTACCTGCCGCTGAAGGTGATCAGG
GCCCAGCTGGACGCCCAGCCCGACGGTGAGTTGCCACCATTCGGATCTCCTTACGTTCTACCGCGATTGGTGCCCGTAGC
CGGCGACAGTGCTGGCGGCGTCGGGTCGGACACCGCGTCCGTGTCGCTCACGGGTATCCGGCTCAGTCGGGAAGACCTCC
TGGAACGATCGGAAGTGGCCGACGAGCTACTGACGGCCCTGCTCAAAGCCGGTGTGATCACCACCGGGCCGGGCGGCTTC
TTCGACGAACACGCCGTCGTGATCCTGCAATGCGCACGAGCGCTGGCCGAATACGGCGTCGAGCCGCGGCATCTACGCGC
CTTCCGCTCCGCGGCCGACCGGCAGTCCGACCTGATTGCCCAGATTGCCGGCCCGCTCGTCAAGGCCGGCAAGGCCGGTG
CCCGCGACCGGGCCGACGACTTGGCCCGTGAGGTGGCCGCGCTTGCTATAACTTTGCACACGTCGCTGATCAAGTCTGCG
GTTCGCGACGTTCTTCACCGCTGA

Upstream 100 bases:

>100_bases
CGGTGCTGGCGAACGGCGACGAGGTCCAGATCGGCAAGTTCCGGTTGGTGTTCTTGACCGGACCCAAGCAAGGCGAGGAT
GACGGGAGTACCGGGGGCCC

Downstream 100 bases:

>100_bases
GGACTAGACTTCGTTCGACAGCTTGGTGTTCGACGTCACGGTAGAGACGTGGCGCCCACCGCGTCGTCGCACCGAGCGTG
AGTCGGACACCGGTTGCATG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MSAPDSPALAGMSIGAVLDLLRPDFPDVTISKIRFLEAEGLVTPRRASSGYRRFTAYDCARLRFILTAQRDHYLPLKVIR
AQLDAQPDGELPPFGSPYVLPRLVPVAGDSAGGVGSDTASVSLTGIRLSREDLLERSEVADELLTALLKAGVITTGPGGF
FDEHAVVILQCARALAEYGVEPRHLRAFRSAADRQSDLIAQIAGPLVKAGKAGARDRADDLAREVAALAITLHTSLIKSA
VRDVLHR

Sequences:

>Translated_247_residues
MSAPDSPALAGMSIGAVLDLLRPDFPDVTISKIRFLEAEGLVTPRRASSGYRRFTAYDCARLRFILTAQRDHYLPLKVIR
AQLDAQPDGELPPFGSPYVLPRLVPVAGDSAGGVGSDTASVSLTGIRLSREDLLERSEVADELLTALLKAGVITTGPGGF
FDEHAVVILQCARALAEYGVEPRHLRAFRSAADRQSDLIAQIAGPLVKAGKAGARDRADDLAREVAALAITLHTSLIKSA
VRDVLHR
>Mature_246_residues
SAPDSPALAGMSIGAVLDLLRPDFPDVTISKIRFLEAEGLVTPRRASSGYRRFTAYDCARLRFILTAQRDHYLPLKVIRA
QLDAQPDGELPPFGSPYVLPRLVPVAGDSAGGVGSDTASVSLTGIRLSREDLLERSEVADELLTALLKAGVITTGPGGFF
DEHAVVILQCARALAEYGVEPRHLRAFRSAADRQSDLIAQIAGPLVKAGKAGARDRADDLAREVAALAITLHTSLIKSAV
RDVLHR

Specific function: Unknown

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1828_MYCTU (P67669)

Other databases:

- EMBL:   BX842577
- EMBL:   AE000516
- PIR:   E70721
- RefSeq:   NP_216344.1
- RefSeq:   NP_336335.1
- ProteinModelPortal:   P67669
- EnsemblBacteria:   EBMYCT00000003812
- EnsemblBacteria:   EBMYCT00000070788
- GeneID:   885336
- GeneID:   923748
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1876
- KEGG:   mtu:Rv1828
- TIGR:   MT1876
- TubercuList:   Rv1828
- GeneTree:   EBGT00050000017385
- HOGENOM:   HBG429114
- OMA:   MQRDHYL
- ProtClustDB:   CLSK791417
- GO:   GO:0005829
- GO:   GO:0040007
- InterPro:   IPR009061
- InterPro:   IPR000551
- SMART:   SM00422

Pfam domain/function: PF00376 MerR; SSF46955 Putativ_DNA_bind

EC number: NA

Molecular weight: Translated: 26444; Mature: 26312

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS00552 HTH_MERR_1; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPDSPALAGMSIGAVLDLLRPDFPDVTISKIRFLEAEGLVTPRRASSGYRRFTAYDCA
CCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
RLRFILTAQRDHYLPLKVIRAQLDAQPDGELPPFGSPYVLPRLVPVAGDSAGGVGSDTAS
HHHHHEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEECCCCCCCCCCCCCCE
VSLTGIRLSREDLLERSEVADELLTALLKAGVITTGPGGFFDEHAVVILQCARALAEYGV
EEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHCCC
EPRHLRAFRSAADRQSDLIAQIAGPLVKAGKAGARDRADDLAREVAALAITLHTSLIKSA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VRDVLHR
HHHHHCC
>Mature Secondary Structure 
SAPDSPALAGMSIGAVLDLLRPDFPDVTISKIRFLEAEGLVTPRRASSGYRRFTAYDCA
CCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
RLRFILTAQRDHYLPLKVIRAQLDAQPDGELPPFGSPYVLPRLVPVAGDSAGGVGSDTAS
HHHHHEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEECCCCCCCCCCCCCCE
VSLTGIRLSREDLLERSEVADELLTALLKAGVITTGPGGFFDEHAVVILQCARALAEYGV
EEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHCCC
EPRHLRAFRSAADRQSDLIAQIAGPLVKAGKAGARDRADDLAREVAALAITLHTSLIKSA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VRDVLHR
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036