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The map label for this gene is 121637718

Identifier: 121637718

GI number: 121637718

Start: 2059258

End: 2059962

Strand: Direct

Name: 121637718

Synonym: BCG_1850

Alternate gene names: NA

Gene position: 2059258-2059962 (Clockwise)

Preceding gene: 121637717

Following gene: 121637720

Centisome position: 47.07

GC content: 63.97

Gene sequence:

>705_bases
TTGTGTCAGACTTGCCGCGTGGGCAAGCGCCGGGATGCGAGGGAACAGATCGAGGCGAAAATTGTCGAACTCGGCCGTCG
CCAGCTGCTGGATCACGGCGCGGCCGGGTTGTCGCTTCGGGCAATTGCCCGCAACCTGGGCATGGTGTCCTCGGCCGTAT
ACCGCTATGTGTCCAGTCGTGATGAGCTGTTGACTTTGCTGCTCGTCGACGCCTACTCCGACCTGGCCGATACCGTGGAC
CGAGCCCGCGACGACACCGTCGCCGACTCGTGGAGTGACGACGTCATCGCAATCGCTCGAGCGGTGCGCGGTTGGGCAGT
CACTAACCCCGCCCGCTGGGCCTTGCTATACGGTAGCCCGGTTCCTGGTTATCACGCGCCGCCTGACCGTACCGCGGGCG
TCGCCACCCGCGTGGTCGGAGCGTTCTTCGACGCGATCGCCGCGGGAATCGCCACCGGAGACATCAGGTTAACCGATGAC
GTTGCGCCGCAGCCGATGTCATCGGACTTCGAAAAGATCCGGCAGGAGTTCGGCTTTCCCGGCGACGATCGTGTCGTCAC
AAAGTGCTTTCTGCTCTGGGCGGGCGTGGTGGGCGCGATCAGCCTGGAGGTATTCGGTCAGTACGGGGCCGACATGCTAA
CCGATCCAGGAGTGGTTTTCGATGCCCAGACACGGCTGCTGGTGGCCGTGCTGGCCGAGCATTGA

Upstream 100 bases:

>100_bases
AGGTTCACGCGGATCTCGGCGTGACGCCCCTTGCTTAGCAAGCACCCCGTTAGCGGCCACCAGGTTGATCGCCGTGTGTT
TGCTAGAGCGGTGATCTCGG

Downstream 100 bases:

>100_bases
AGCTGCTGCAATCGGCGTGTCCAGCCGGAATTAGAACGTGTTCACTCAAGGCTACCAGTGCTGACACTTGCGGTGGTGGC
AAATGCAATCTGAGCCCTTT

Product: putative transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MCQTCRVGKRRDAREQIEAKIVELGRRQLLDHGAAGLSLRAIARNLGMVSSAVYRYVSSRDELLTLLLVDAYSDLADTVD
RARDDTVADSWSDDVIAIARAVRGWAVTNPARWALLYGSPVPGYHAPPDRTAGVATRVVGAFFDAIAAGIATGDIRLTDD
VAPQPMSSDFEKIRQEFGFPGDDRVVTKCFLLWAGVVGAISLEVFGQYGADMLTDPGVVFDAQTRLLVAVLAEH

Sequences:

>Translated_234_residues
MCQTCRVGKRRDAREQIEAKIVELGRRQLLDHGAAGLSLRAIARNLGMVSSAVYRYVSSRDELLTLLLVDAYSDLADTVD
RARDDTVADSWSDDVIAIARAVRGWAVTNPARWALLYGSPVPGYHAPPDRTAGVATRVVGAFFDAIAAGIATGDIRLTDD
VAPQPMSSDFEKIRQEFGFPGDDRVVTKCFLLWAGVVGAISLEVFGQYGADMLTDPGVVFDAQTRLLVAVLAEH
>Mature_234_residues
MCQTCRVGKRRDAREQIEAKIVELGRRQLLDHGAAGLSLRAIARNLGMVSSAVYRYVSSRDELLTLLLVDAYSDLADTVD
RARDDTVADSWSDDVIAIARAVRGWAVTNPARWALLYGSPVPGYHAPPDRTAGVATRVVGAFFDAIAAGIATGDIRLTDD
VAPQPMSSDFEKIRQEFGFPGDDRVVTKCFLLWAGVVGAISLEVFGQYGADMLTDPGVVFDAQTRLLVAVLAEH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1816_MYCTU (P67438)

Other databases:

- EMBL:   BX842577
- EMBL:   AE000516
- PIR:   A70720
- RefSeq:   NP_216332.1
- RefSeq:   NP_336323.1
- ProteinModelPortal:   P67438
- SMR:   P67438
- EnsemblBacteria:   EBMYCT00000003103
- EnsemblBacteria:   EBMYCT00000071677
- GeneID:   885340
- GeneID:   923767
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1864
- KEGG:   mtu:Rv1816
- TIGR:   MT1864
- TubercuList:   Rv1816
- GeneTree:   EBGT00050000014737
- HOGENOM:   HBG580138
- OMA:   YRYVASR
- ProtClustDB:   CLSK791410
- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647
- Gene3D:   G3DSA:1.10.357.10

Pfam domain/function: PF00440 TetR_N; SSF46689 Homeodomain_like; SSF48498 TetR_like_C

EC number: NA

Molecular weight: Translated: 25353; Mature: 25353

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS01081 HTH_TETR_1; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x16690d5c)-;

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCQTCRVGKRRDAREQIEAKIVELGRRQLLDHGAAGLSLRAIARNLGMVSSAVYRYVSSR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCH
DELLTLLLVDAYSDLADTVDRARDDTVADSWSDDVIAIARAVRGWAVTNPARWALLYGSP
HHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCC
VPGYHAPPDRTAGVATRVVGAFFDAIAAGIATGDIRLTDDVAPQPMSSDFEKIRQEFGFP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHCCCC
GDDRVVTKCFLLWAGVVGAISLEVFGQYGADMLTDPGVVFDAQTRLLVAVLAEH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEECHHHHHHHHHHHCH
>Mature Secondary Structure
MCQTCRVGKRRDAREQIEAKIVELGRRQLLDHGAAGLSLRAIARNLGMVSSAVYRYVSSR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCH
DELLTLLLVDAYSDLADTVDRARDDTVADSWSDDVIAIARAVRGWAVTNPARWALLYGSP
HHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCC
VPGYHAPPDRTAGVATRVVGAFFDAIAAGIATGDIRLTDDVAPQPMSSDFEKIRQEFGFP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHCCCC
GDDRVVTKCFLLWAGVVGAISLEVFGQYGADMLTDPGVVFDAQTRLLVAVLAEH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEECHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036