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The map label for this gene is PPE25 [H]

Identifier: 121637688

GI number: 121637688

Start: 2026306

End: 2027400

Strand: Direct

Name: PPE25 [H]

Synonym: BCG_1819

Alternate gene names: 121637688

Gene position: 2026306-2027400 (Clockwise)

Preceding gene: 121637687

Following gene: 121637689

Centisome position: 46.32

GC content: 67.03

Gene sequence:

>1095_bases
TTGGACTTCGGGGCGTTACCGCCGGAGATCAATTCGGGCCGTATGTATTGCGGTCCGGGGTCGGGGCCGATGCTGGCTGC
GGCCGCGGCCTGGGACGGGGTGGCCGTGGAGTTGGGGTTGGCTGCGACCGGTTATGCGTCGGTGATAGCCGAGCTGACCG
GTGCGCCGTGGGTGGGTGCGGCGTCGTTGTCGATGGTGGCGGCGGCCACGCCGTATGTGGCCTGGCTGAGCCAAGCCGCG
GCGCGGGCCGAGCAGGCGGGGATGCAGGCCGCGGCGGCCGCGGCGGCTTATGAGGCCGCTTTTGTGATGACGGTGCCGCC
GCCGGTGATTACGGCGAATCGGGTTTTGGTGATGACGCTGATTGCGACCAATTTTTTCGGTCAGAACTCGGCGGCGATCG
CGGTCGCTGAGGCGCAGTACGCCGAAATGTGGGCGCAAGACGCCGTTGCTATGTATGGCTATGCGGCTGCGTCGGCGAGC
GCGTCGCGGTTGATTCCGTTCGCGGCGCCGCCGAAGACCACCAACTCCGCTGGGGTGGTCGCACAGGTGGCTGCGGTCGC
GGCGATGCCTGGACTGCTGCAACGACTTTCGTCGGCTGCATCGGTCAGCTGGTCGAATCCCAATGATTGGTGGCTCGTGC
GGTTGCTGGGCTCGATTACCCCCACGGAAAGGACGACGATCGTTCGTTTGCTCGGTCAGTCGTACTTCGCGACGGGCATG
GCGCAGTTCTTCGCCTCGATCGCACAGCAGCTGACCTTCGGCCCAGGGGGCACAACGGCTGGCTCCGGCGGAGCCTGGTA
CCCAACGCCGCAATTCGCCGGCCTGGGTGCAAGCCGGGCGGTGTCGGCGAGTTTGGCGCGGGCCAACAAGATTGGGGCTC
TGTCGGTTCCGCCGAGCTGGGTCAAAACGACTGCACTGACCGAACCGGGCGCCCACGCGGTGAGCGCCAACCCTACCGTC
GGTTCGTCACACGGACCGCATGGCCTGCTCCGCGGACTGCCGCTAGGGTCGCGGATCACTCGGCGTAGCGGCGCCTTTGC
CCACCGATATGGGTTCCGTCACAGTGTGGTTGCCCGCCCGCCATCGGCCGGATAA

Upstream 100 bases:

>100_bases
TCGATGCCGAGCGCGCGTCTCGTTGGCCACGTTTGGTGGCAATGCTCATCAGGGCTCATCCGGATCGCCAACGCGATCGT
GTGTGGAGAGGGAGGACTGG

Downstream 100 bases:

>100_bases
CGCCATGACCTCAGCTCGGCAGAAATGACAATGCTCCCAAAGGCGTGAGCACCCGAAGACAACTAAGCAGGAGATCGCAT
GTCGTTTGTGACTACCCAAC

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MDFGALPPEINSGRMYCGPGSGPMLAAAAAWDGVAVELGLAATGYASVIAELTGAPWVGAASLSMVAAATPYVAWLSQAA
ARAEQAGMQAAAAAAAYEAAFVMTVPPPVITANRVLVMTLIATNFFGQNSAAIAVAEAQYAEMWAQDAVAMYGYAAASAS
ASRLIPFAAPPKTTNSAGVVAQVAAVAAMPGLLQRLSSAASVSWSNPNDWWLVRLLGSITPTERTTIVRLLGQSYFATGM
AQFFASIAQQLTFGPGGTTAGSGGAWYPTPQFAGLGASRAVSASLARANKIGALSVPPSWVKTTALTEPGAHAVSANPTV
GSSHGPHGLLRGLPLGSRITRRSGAFAHRYGFRHSVVARPPSAG

Sequences:

>Translated_364_residues
MDFGALPPEINSGRMYCGPGSGPMLAAAAAWDGVAVELGLAATGYASVIAELTGAPWVGAASLSMVAAATPYVAWLSQAA
ARAEQAGMQAAAAAAAYEAAFVMTVPPPVITANRVLVMTLIATNFFGQNSAAIAVAEAQYAEMWAQDAVAMYGYAAASAS
ASRLIPFAAPPKTTNSAGVVAQVAAVAAMPGLLQRLSSAASVSWSNPNDWWLVRLLGSITPTERTTIVRLLGQSYFATGM
AQFFASIAQQLTFGPGGTTAGSGGAWYPTPQFAGLGASRAVSASLARANKIGALSVPPSWVKTTALTEPGAHAVSANPTV
GSSHGPHGLLRGLPLGSRITRRSGAFAHRYGFRHSVVARPPSAG
>Mature_364_residues
MDFGALPPEINSGRMYCGPGSGPMLAAAAAWDGVAVELGLAATGYASVIAELTGAPWVGAASLSMVAAATPYVAWLSQAA
ARAEQAGMQAAAAAAAYEAAFVMTVPPPVITANRVLVMTLIATNFFGQNSAAIAVAEAQYAEMWAQDAVAMYGYAAASAS
ASRLIPFAAPPKTTNSAGVVAQVAAVAAMPGLLQRLSSAASVSWSNPNDWWLVRLLGSITPTERTTIVRLLGQSYFATGM
AQFFASIAQQLTFGPGGTTAGSGGAWYPTPQFAGLGASRAVSASLARANKIGALSVPPSWVKTTALTEPGAHAVSANPTV
GSSHGPHGLLRGLPLGSRITRRSGAFAHRYGFRHSVVARPPSAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022171
- InterPro:   IPR000030 [H]

Pfam domain/function: PF12484 PE_PPE_C; PF00823 PPE [H]

EC number: NA

Molecular weight: Translated: 36961; Mature: 36961

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFGALPPEINSGRMYCGPGSGPMLAAAAAWDGVAVELGLAATGYASVIAELTGAPWVGA
CCCCCCCCCCCCCEEEECCCCCCEEEEHHCCCCEEEEECCCHHHHHHHHHHHCCCCCCCH
ASLSMVAAATPYVAWLSQAAARAEQAGMQAAAAAAAYEAAFVMTVPPPVITANRVLVMTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEECCHHHHHHH
IATNFFGQNSAAIAVAEAQYAEMWAQDAVAMYGYAAASASASRLIPFAAPPKTTNSAGVV
HHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCHHH
AQVAAVAAMPGLLQRLSSAASVSWSNPNDWWLVRLLGSITPTERTTIVRLLGQSYFATGM
HHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
AQFFASIAQQLTFGPGGTTAGSGGAWYPTPQFAGLGASRAVSASLARANKIGALSVPPSW
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEECCCCHH
VKTTALTEPGAHAVSANPTVGSSHGPHGLLRGLPLGSRITRRSGAFAHRYGFRHSVVARP
HHHHCCCCCCCCEEECCCCCCCCCCCCHHHHCCCCCCHHHHHCCCHHHHHCCCCCEECCC
PSAG
CCCC
>Mature Secondary Structure
MDFGALPPEINSGRMYCGPGSGPMLAAAAAWDGVAVELGLAATGYASVIAELTGAPWVGA
CCCCCCCCCCCCCEEEECCCCCCEEEEHHCCCCEEEEECCCHHHHHHHHHHHCCCCCCCH
ASLSMVAAATPYVAWLSQAAARAEQAGMQAAAAAAAYEAAFVMTVPPPVITANRVLVMTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEECCHHHHHHH
IATNFFGQNSAAIAVAEAQYAEMWAQDAVAMYGYAAASASASRLIPFAAPPKTTNSAGVV
HHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCHHH
AQVAAVAAMPGLLQRLSSAASVSWSNPNDWWLVRLLGSITPTERTTIVRLLGQSYFATGM
HHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
AQFFASIAQQLTFGPGGTTAGSGGAWYPTPQFAGLGASRAVSASLARANKIGALSVPPSW
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEECCCCHH
VKTTALTEPGAHAVSANPTVGSSHGPHGLLRGLPLGSRITRRSGAFAHRYGFRHSVVARP
HHHHCCCCCCCCEEECCCCCCCCCCCCHHHHCCCCCCHHHHHCCCHHHHHCCCCCEECCC
PSAG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]