BacMap

Definition	Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome.
Accession	NC_008769
Length	4,374,522

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The map label for this gene is gabD2

Identifier: 121637639

GI number: 121637639

Start: 1962836

End: 1964392

Strand: Direct

Name: gabD2

Synonym: BCG_1770

Alternate gene names: 121637639

Gene position: 1962836-1964392 (Clockwise)

Preceding gene: 121637635

Following gene: 121637646

Centisome position: 44.87

GC content: 65.77

Gene sequence:

>1557_bases
ATGCCTGCACCCTCGGCCGAGGTTTTCGATCGCTTGCGTAACCTGGCCGCGATCAAGGACGTCGCCGCACGTCCGACCAG
GACGATCGACGAGGTCTTCACCGGCAAGCCGTTGACTACGATTCCGGTCGGCACGGCCGCGGACGTCGAAGCGGCATTCG
CCGAAGCTCGCGCGGCGCAGACCGACTGGGCGAAGCGTCCCGTCATCGAGCGAGCTGCAGTCATCCGCCGCTATCGCGAC
CTGGTCATCGAGAACCGCGAGTTCCTCATGGACCTCCTGCAAGCCGAGGCGGGCAAGGCCCGATGGGCGGCGCAAGAGGA
AATTGTCGATCTGATCGCGAACGCGAATTATTACGCACGAGTCTGTGTGGACCTGCTGAAGCCCCGTAAGGCACAGCCGC
TGCTGCCCGGGATAGGCAAGACCACGGTGTGCTATCAACCGAAGGGCGTGGTGGGGGTGATCTCGCCGTGGAACTACCCC
ATGACGCTTACGGTGTCGGACTCGGTGCCCGCGCTGGTGGCCGGTAACGCGGTGGTGCTCAAGCCGGACAGCCAGACGCC
GTATTGTGCGCTCGCGTGTGCCGAGCTGCTGTATCGGGCGGGTCTGCCGCGAGCGCTGTATGCGATCGTGCCCGGTCCGG
GCTCGGTGGTGGGCACCGCCATCACCGACAACTGCGACTACCTGATGTTCACCGGTTCATCGGCGACCGGCAGCCGCCTC
GCCGAGCACGCCGGCCGCCGGCTTATCGGTTTCTCGGCCGAACTTGGCGGCAAGAACCCCATGATCGTGGCGCGGGGTGC
CAACCTCGACAAGGTCGCCAAGGCGGCCACCCGTGCCTGCTTCTCGAACGCCGGCCAGCTGTGCATCTCCATTGAGCGGA
TCTACGTCGAAAAGGACATCGCCGAGGAGTTCACCCGGAAGTTCGGCGATGCGGTGCGGAACATGAAGCTCGGCACCGCA
TACGACTTCTCGGTCGACATGGGTAGTTTGATCTCCGAAGCACAGCTGAAAACCGTGTCCGGTCACGTGGATGACGCGAC
GGCCAAGGGCGCCAAGGTGATTGCGGGCGGCAAGGCTCGACCCGACATCGGGCCGCTGTTCTACGAGCCGACCGTGCTGA
CCAACGTCGCACCCGAAATGGAATGCGCGGCCAACGAGACGTTCGGGCCGGTGGTCTCGATCTACCCGGTCGCCGACGTG
GACGAAGCCGTCGAAAAGGCCAACGACACCGACTACGGGCTCAACGCCAGCGTCTGGGCCGGCTCCACCGCGGAGGGCCA
GAGGATCGCCGCCCGGCTGCGGTCGGGGACGGTGAACGTCGACGAGGGGTACGCGTTCGCCTGGGGCAGCCTCAGCGCGC
CGATGGGCGGGATGGGCCTCTCGGGGGTCGGCCGCCGGCACGGTCCGGAGGGCTTGCTCAAGTACACCGAATCACAGACG
ATCGCGACCGCCCGCGTGTTCAATCTCGATCCGCCCTTCGGCATCCCGGCCACAGTCTGGCAGAAGTCACTGTTACCCAT
CGTGCGCACCGTGATGAAGCTTCCCGGCCGCAGGTGA

Upstream 100 bases:

>100_bases
CAAGAAGAACCCGGCATTCGTCGAGAATGCCTTTGGTCACCAATCGCAGGCCGATACTCTGTGCCCTAGACACCCGCATT
TCTTCGAAAGAGGTGACGAT

Downstream 100 bases:

>100_bases
CGGCGCGGCCTAGCGCCACTTGATGCCGCACCCGATCGACGGTCGTTGGTCGGGGTTGACTGGCCGCCCGGCGAGCAGGG
CGTCGACCGCGGCCCGGACG

Product: succinic semialdehyde dehydrogenase

Products: NA

Alternate protein names: SSADH 2; SSDH 2

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MPAPSAEVFDRLRNLAAIKDVAARPTRTIDEVFTGKPLTTIPVGTAADVEAAFAEARAAQTDWAKRPVIERAAVIRRYRD
LVIENREFLMDLLQAEAGKARWAAQEEIVDLIANANYYARVCVDLLKPRKAQPLLPGIGKTTVCYQPKGVVGVISPWNYP
MTLTVSDSVPALVAGNAVVLKPDSQTPYCALACAELLYRAGLPRALYAIVPGPGSVVGTAITDNCDYLMFTGSSATGSRL
AEHAGRRLIGFSAELGGKNPMIVARGANLDKVAKAATRACFSNAGQLCISIERIYVEKDIAEEFTRKFGDAVRNMKLGTA
YDFSVDMGSLISEAQLKTVSGHVDDATAKGAKVIAGGKARPDIGPLFYEPTVLTNVAPEMECAANETFGPVVSIYPVADV
DEAVEKANDTDYGLNASVWAGSTAEGQRIAARLRSGTVNVDEGYAFAWGSLSAPMGGMGLSGVGRRHGPEGLLKYTESQT
IATARVFNLDPPFGIPATVWQKSLLPIVRTVMKLPGRR

Sequences:

>Translated_518_residues
MPAPSAEVFDRLRNLAAIKDVAARPTRTIDEVFTGKPLTTIPVGTAADVEAAFAEARAAQTDWAKRPVIERAAVIRRYRD
LVIENREFLMDLLQAEAGKARWAAQEEIVDLIANANYYARVCVDLLKPRKAQPLLPGIGKTTVCYQPKGVVGVISPWNYP
MTLTVSDSVPALVAGNAVVLKPDSQTPYCALACAELLYRAGLPRALYAIVPGPGSVVGTAITDNCDYLMFTGSSATGSRL
AEHAGRRLIGFSAELGGKNPMIVARGANLDKVAKAATRACFSNAGQLCISIERIYVEKDIAEEFTRKFGDAVRNMKLGTA
YDFSVDMGSLISEAQLKTVSGHVDDATAKGAKVIAGGKARPDIGPLFYEPTVLTNVAPEMECAANETFGPVVSIYPVADV
DEAVEKANDTDYGLNASVWAGSTAEGQRIAARLRSGTVNVDEGYAFAWGSLSAPMGGMGLSGVGRRHGPEGLLKYTESQT
IATARVFNLDPPFGIPATVWQKSLLPIVRTVMKLPGRR
>Mature_517_residues
PAPSAEVFDRLRNLAAIKDVAARPTRTIDEVFTGKPLTTIPVGTAADVEAAFAEARAAQTDWAKRPVIERAAVIRRYRDL
VIENREFLMDLLQAEAGKARWAAQEEIVDLIANANYYARVCVDLLKPRKAQPLLPGIGKTTVCYQPKGVVGVISPWNYPM
TLTVSDSVPALVAGNAVVLKPDSQTPYCALACAELLYRAGLPRALYAIVPGPGSVVGTAITDNCDYLMFTGSSATGSRLA
EHAGRRLIGFSAELGGKNPMIVARGANLDKVAKAATRACFSNAGQLCISIERIYVEKDIAEEFTRKFGDAVRNMKLGTAY
DFSVDMGSLISEAQLKTVSGHVDDATAKGAKVIAGGKARPDIGPLFYEPTVLTNVAPEMECAANETFGPVVSIYPVADVD
EAVEKANDTDYGLNASVWAGSTAEGQRIAARLRSGTVNVDEGYAFAWGSLSAPMGGMGLSGVGRRHGPEGLLKYTESQTI
ATARVFNLDPPFGIPATVWQKSLLPIVRTVMKLPGRR

Specific function: Catalyzes the NADP(+)-dependent oxidation of succinate semialdehyde to succinate. Although it has succinate semialdehyde dehydrogenase activity, is likely to act physiologically on a different aldehyde(s)

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family

Homologues:

Organism=Homo sapiens, GI12007648, Length=460, Percent_Identity=34.3478260869565, Blast_Score=243, Evalue=4e-64,
Organism=Homo sapiens, GI153266822, Length=462, Percent_Identity=33.5497835497836, Blast_Score=232, Evalue=5e-61,
Organism=Homo sapiens, GI4507229, Length=431, Percent_Identity=34.1067285382831, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI25777724, Length=459, Percent_Identity=33.7690631808279, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI21361176, Length=457, Percent_Identity=33.4792122538293, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI238814322, Length=432, Percent_Identity=31.9444444444444, Blast_Score=221, Evalue=2e-57,
Organism=Homo sapiens, GI25777728, Length=420, Percent_Identity=34.7619047619048, Blast_Score=220, Evalue=3e-57,
Organism=Homo sapiens, GI25777732, Length=490, Percent_Identity=31.8367346938775, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI25777721, Length=444, Percent_Identity=32.8828828828829, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI21614513, Length=429, Percent_Identity=32.1678321678322, Blast_Score=217, Evalue=3e-56,
Organism=Homo sapiens, GI25777730, Length=457, Percent_Identity=31.7286652078775, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI115387104, Length=477, Percent_Identity=30.398322851153, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI25777726, Length=457, Percent_Identity=30.6345733041575, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI301500698, Length=284, Percent_Identity=36.9718309859155, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI25952152, Length=453, Percent_Identity=30.242825607064, Blast_Score=176, Evalue=6e-44,
Organism=Homo sapiens, GI73466520, Length=435, Percent_Identity=27.1264367816092, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI4557303, Length=435, Percent_Identity=27.1264367816092, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI206597441, Length=445, Percent_Identity=26.9662921348315, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI206597439, Length=445, Percent_Identity=26.9662921348315, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI22907049, Length=445, Percent_Identity=26.9662921348315, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI11095441, Length=474, Percent_Identity=25.7383966244726, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI73695881, Length=370, Percent_Identity=29.7297297297297, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI73695879, Length=370, Percent_Identity=29.7297297297297, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI310128103, Length=466, Percent_Identity=26.8240343347639, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI188035924, Length=466, Percent_Identity=26.8240343347639, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI310128093, Length=457, Percent_Identity=26.4770240700219, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI4502043, Length=419, Percent_Identity=27.6849642004773, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI238814371, Length=419, Percent_Identity=27.6849642004773, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI71773324, Length=331, Percent_Identity=30.2114803625378, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI25777736, Length=455, Percent_Identity=26.8131868131868, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI25777734, Length=455, Percent_Identity=26.8131868131868, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI238859541, Length=456, Percent_Identity=26.9736842105263, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI310128091, Length=457, Percent_Identity=25.382932166302, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI223972651, Length=457, Percent_Identity=26.0393873085339, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI310128089, Length=338, Percent_Identity=27.2189349112426, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI310128097, Length=262, Percent_Identity=27.8625954198473, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI310128095, Length=319, Percent_Identity=26.6457680250784, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI223972653, Length=452, Percent_Identity=24.3362831858407, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI310128087, Length=279, Percent_Identity=27.5985663082437, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI310128101, Length=225, Percent_Identity=25.7777777777778, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI310128099, Length=225, Percent_Identity=25.7777777777778, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI1789015, Length=450, Percent_Identity=34.6666666666667, Blast_Score=251, Evalue=6e-68,
Organism=Escherichia coli, GI87081896, Length=462, Percent_Identity=33.3333333333333, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1786504, Length=462, Percent_Identity=32.4675324675325, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI1787684, Length=455, Percent_Identity=31.8681318681319, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1787558, Length=464, Percent_Identity=32.1120689655172, Blast_Score=204, Evalue=8e-54,
Organism=Escherichia coli, GI1787715, Length=446, Percent_Identity=34.304932735426, Blast_Score=204, Evalue=2e-53,
Organism=Escherichia coli, GI87081926, Length=454, Percent_Identity=30.6167400881057, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI87082295, Length=478, Percent_Identity=29.4979079497908, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1788042, Length=436, Percent_Identity=29.8165137614679, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1787250, Length=437, Percent_Identity=27.9176201372998, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1787653, Length=358, Percent_Identity=24.5810055865922, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI133930964, Length=469, Percent_Identity=34.1151385927505, Blast_Score=234, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17562198, Length=474, Percent_Identity=32.2784810126582, Blast_Score=218, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI25143876, Length=458, Percent_Identity=31.6593886462882, Blast_Score=215, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI25143874, Length=458, Percent_Identity=31.6593886462882, Blast_Score=215, Evalue=6e-56,
Organism=Caenorhabditis elegans, GI17551164, Length=492, Percent_Identity=31.7073170731707, Blast_Score=213, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI25144435, Length=470, Percent_Identity=31.9148936170213, Blast_Score=208, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI71995606, Length=475, Percent_Identity=30.1052631578947, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI32564736, Length=418, Percent_Identity=32.7751196172249, Blast_Score=198, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI17534119, Length=439, Percent_Identity=29.6127562642369, Blast_Score=178, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI71995613, Length=415, Percent_Identity=29.6385542168675, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI25146394, Length=438, Percent_Identity=27.6255707762557, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI25146391, Length=444, Percent_Identity=27.4774774774775, Blast_Score=152, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI32566756, Length=444, Percent_Identity=27.4774774774775, Blast_Score=152, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI115534176, Length=461, Percent_Identity=28.1995661605206, Blast_Score=151, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI17564084, Length=434, Percent_Identity=26.9585253456221, Blast_Score=151, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI17534447, Length=502, Percent_Identity=27.6892430278884, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI32564151, Length=442, Percent_Identity=27.6018099547511, Blast_Score=133, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71986308, Length=504, Percent_Identity=24.4047619047619, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI115532534, Length=410, Percent_Identity=29.2682926829268, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71990744, Length=331, Percent_Identity=25.9818731117825, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320917, Length=472, Percent_Identity=32.8389830508475, Blast_Score=238, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6319478, Length=469, Percent_Identity=31.3432835820896, Blast_Score=219, Evalue=8e-58,
Organism=Saccharomyces cerevisiae, GI6324950, Length=472, Percent_Identity=31.3559322033898, Blast_Score=218, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6325196, Length=465, Percent_Identity=30.9677419354839, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6323821, Length=465, Percent_Identity=29.8924731182796, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6321828, Length=472, Percent_Identity=27.9661016949153, Blast_Score=190, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6323822, Length=465, Percent_Identity=29.4623655913978, Blast_Score=189, Evalue=6e-49,
Organism=Saccharomyces cerevisiae, GI6323757, Length=430, Percent_Identity=28.1395348837209, Blast_Score=130, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6321826, Length=418, Percent_Identity=26.3157894736842, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281362580, Length=490, Percent_Identity=32.2448979591837, Blast_Score=236, Evalue=4e-62,
Organism=Drosophila melanogaster, GI62472918, Length=490, Percent_Identity=32.2448979591837, Blast_Score=236, Evalue=4e-62,
Organism=Drosophila melanogaster, GI62472926, Length=490, Percent_Identity=32.2448979591837, Blast_Score=236, Evalue=4e-62,
Organism=Drosophila melanogaster, GI62472936, Length=490, Percent_Identity=32.2448979591837, Blast_Score=236, Evalue=4e-62,
Organism=Drosophila melanogaster, GI21356737, Length=490, Percent_Identity=32.2448979591837, Blast_Score=236, Evalue=4e-62,
Organism=Drosophila melanogaster, GI20129399, Length=460, Percent_Identity=31.9565217391304, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI24650465, Length=455, Percent_Identity=32.0879120879121, Blast_Score=215, Evalue=5e-56,
Organism=Drosophila melanogaster, GI24585660, Length=471, Percent_Identity=30.7855626326964, Blast_Score=212, Evalue=4e-55,
Organism=Drosophila melanogaster, GI24666674, Length=478, Percent_Identity=26.3598326359833, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI45552499, Length=334, Percent_Identity=28.4431137724551, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281360303, Length=334, Percent_Identity=28.4431137724551, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281360301, Length=335, Percent_Identity=28.6567164179104, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281360299, Length=335, Percent_Identity=28.6567164179104, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281360297, Length=335, Percent_Identity=28.6567164179104, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281360295, Length=335, Percent_Identity=28.6567164179104, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24586250, Length=335, Percent_Identity=28.6567164179104, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24638878, Length=459, Percent_Identity=23.5294117647059, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24638876, Length=459, Percent_Identity=23.5294117647059, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24668425, Length=460, Percent_Identity=25.8695652173913, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24668417, Length=460, Percent_Identity=25.8695652173913, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24668413, Length=460, Percent_Identity=25.8695652173913, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28574525, Length=440, Percent_Identity=24.5454545454545, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281360293, Length=154, Percent_Identity=31.8181818181818, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GABD2_MYCBO (Q7TZP3)

Other databases:

- EMBL:   BX248340
- RefSeq:   NP_855412.1
- HSSP:   Q28399
- ProteinModelPortal:   Q7TZP3
- SMR:   Q7TZP3
- EnsemblBacteria:   EBMYCT00000015795
- GeneID:   1092783
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1760
- GeneTree:   EBGT00050000015660
- HOGENOM:   HBG752218
- OMA:   DTEYGLN
- ProtClustDB:   PRK09407
- BioCyc:   MBOV233413:MB1760-MONOMER
- BRENDA:   1.2.1.16
- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- Gene3D:   G3DSA:3.40.309.10
- Gene3D:   G3DSA:3.40.605.10
- PANTHER:   PTHR11699

Pfam domain/function: PF00171 Aldedh; SSF53720 Aldehyde_DH/Histidinol_DH

EC number: =1.2.1.79

Molecular weight: Translated: 55325; Mature: 55194

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS; PS00687 ALDEHYDE_DEHYDR_GLU; PS00216 SUGAR_TRANSPORT_1

Important sites: ACT_SITE 254-254 ACT_SITE 288-288 BINDING 255-255 BINDING 386-386

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPSAEVFDRLRNLAAIKDVAARPTRTIDEVFTGKPLTTIPVGTAADVEAAFAEARAAQ
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHH
TDWAKRPVIERAAVIRRYRDLVIENREFLMDLLQAEAGKARWAAQEEIVDLIANANYYAR
HHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHH
VCVDLLKPRKAQPLLPGIGKTTVCYQPKGVVGVISPWNYPMTLTVSDSVPALVAGNAVVL
HHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCEEEEECCCCCEEEECCEEEE
KPDSQTPYCALACAELLYRAGLPRALYAIVPGPGSVVGTAITDNCDYLMFTGSSATGSRL
CCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCCEEEEECCCCCHHHH
AEHAGRRLIGFSAELGGKNPMIVARGANLDKVAKAATRACFSNAGQLCISIERIYVEKDI
HHHCCCEEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHH
AEEFTRKFGDAVRNMKLGTAYDFSVDMGSLISEAQLKTVSGHVDDATAKGAKVIAGGKAR
HHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCC
PDIGPLFYEPTVLTNVAPEMECAANETFGPVVSIYPVADVDEAVEKANDTDYGLNASVWA
CCCCCEEECCHHHHCCCCCHHHCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCCEEEC
GSTAEGQRIAARLRSGTVNVDEGYAFAWGSLSAPMGGMGLSGVGRRHGPEGLLKYTESQT
CCCCCHHHHHHHHHCCCEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCE
IATARVFNLDPPFGIPATVWQKSLLPIVRTVMKLPGRR
EEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PAPSAEVFDRLRNLAAIKDVAARPTRTIDEVFTGKPLTTIPVGTAADVEAAFAEARAAQ
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHH
TDWAKRPVIERAAVIRRYRDLVIENREFLMDLLQAEAGKARWAAQEEIVDLIANANYYAR
HHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHH
VCVDLLKPRKAQPLLPGIGKTTVCYQPKGVVGVISPWNYPMTLTVSDSVPALVAGNAVVL
HHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCCEEEEECCCCCEEEECCEEEE
KPDSQTPYCALACAELLYRAGLPRALYAIVPGPGSVVGTAITDNCDYLMFTGSSATGSRL
CCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEEECCCCEEEEECCCCCHHHH
AEHAGRRLIGFSAELGGKNPMIVARGANLDKVAKAATRACFSNAGQLCISIERIYVEKDI
HHHCCCEEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHH
AEEFTRKFGDAVRNMKLGTAYDFSVDMGSLISEAQLKTVSGHVDDATAKGAKVIAGGKAR
HHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCC
PDIGPLFYEPTVLTNVAPEMECAANETFGPVVSIYPVADVDEAVEKANDTDYGLNASVWA
CCCCCEEECCHHHHCCCCCHHHCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCCEEEC
GSTAEGQRIAARLRSGTVNVDEGYAFAWGSLSAPMGGMGLSGVGRRHGPEGLLKYTESQT
CCCCCHHHHHHHHHCCCEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCE
IATARVFNLDPPFGIPATVWQKSLLPIVRTVMKLPGRR
EEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972