BacMap

Definition	Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome.
Accession	NC_008769
Length	4,374,522

Click here to switch to the map view.

The map label for this gene is fabG [H]

Identifier: 121637622

GI number: 121637622

Start: 1947070

End: 1947882

Strand: Direct

Name: fabG [H]

Synonym: BCG_1753

Alternate gene names: 121637622

Gene position: 1947070-1947882 (Clockwise)

Preceding gene: 121637621

Following gene: 121637623

Centisome position: 44.51

GC content: 69.0

Gene sequence:

>813_bases
GTGGAGGAAATGGCGCTGGCTCAGCAGGTGCCGAACCTGGGTCTGGCGCGCTTCAGCGTGCAGGACAAGTCGATCCTGAT
CACCGGCGCGACCGGTTCGTTGGGCCGAGTTGCCGCCCGGGCGCTGGCCGACGCGGGAGCGCGGCTGACACTGGCCGGCG
GCAACTCGGCCGGTCTGGCCGAGCTGGTCAACGGCGCCGGCATCGACGACGCCGCCGTCGTGACCTGCCGGCCGGACAGC
CTGGCCGATGCCCAGCAGATGGTCGAGGCGGCACTGGGCCGATATGGCCGTTTGGACGGAGTGTTGGTGGCCTCGGGCAG
CAACCATGTGGCGCCCATTACCGAGATGGCCGTCGAGGACTTCGACGCTGTGATGGACGCGAACGTGCGGGGTGCCTGGC
TGGTGTGTCGGGCGGCCGGACGGGTGCTGCTCGAGCAGGGTCAGGGCGGCAGCGTGGTGCTGGTGTCGTCCGTTCGCGGC
GGGTTGGGCAATGCCGCCGGTTACAGCGCGTACTGCCCGTCGAAGGCGGGCACCGATCTGTTGGCCAAGACATTGGCGGC
CGAATGGGGCGGTCACGGCATTCGGGTGAACGCGCTGGCGCCGACGGTGTTTCGGTCCGCGGTGACCGAGTGGATGTTCA
CCGACGATCCGAAGGGCCGGGCCACCCGGGAGGCGATGCTCGCCCGGATCCCGTTGCGCCGCTTCGCCGAACCGGAAGAC
TTCGTCGGCGCCCTGATCTATCTGCTCAGCGACGCCTCGAGCTTCTACACCGGCCAGGTGATGTATCTGGACGGCGGGTA
CACCGCATGCTGA

Upstream 100 bases:

>100_bases
TATGTTCAGCTGCATTACGGGATTTAGGTGTTGACACCCGAGCGCTCGGCGCTTACGCTTTCTCGTATAACGGGTGATAA
GTACCGTATTGCGGGAGTAG

Downstream 100 bases:

>100_bases
CCTCGCACGGGTTCTCCCGTGCCGCCGTCGTGGGTGCCGGGCTGATGGGCCGGCGCATCGCCGGCGTGCTGGCCTCGGCG
GGCCTGGATGTCGCCATCAC

Product: putative oxidoreductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MEEMALAQQVPNLGLARFSVQDKSILITGATGSLGRVAARALADAGARLTLAGGNSAGLAELVNGAGIDDAAVVTCRPDS
LADAQQMVEAALGRYGRLDGVLVASGSNHVAPITEMAVEDFDAVMDANVRGAWLVCRAAGRVLLEQGQGGSVVLVSSVRG
GLGNAAGYSAYCPSKAGTDLLAKTLAAEWGGHGIRVNALAPTVFRSAVTEWMFTDDPKGRATREAMLARIPLRRFAEPED
FVGALIYLLSDASSFYTGQVMYLDGGYTAC

Sequences:

>Translated_270_residues
MEEMALAQQVPNLGLARFSVQDKSILITGATGSLGRVAARALADAGARLTLAGGNSAGLAELVNGAGIDDAAVVTCRPDS
LADAQQMVEAALGRYGRLDGVLVASGSNHVAPITEMAVEDFDAVMDANVRGAWLVCRAAGRVLLEQGQGGSVVLVSSVRG
GLGNAAGYSAYCPSKAGTDLLAKTLAAEWGGHGIRVNALAPTVFRSAVTEWMFTDDPKGRATREAMLARIPLRRFAEPED
FVGALIYLLSDASSFYTGQVMYLDGGYTAC
>Mature_270_residues
MEEMALAQQVPNLGLARFSVQDKSILITGATGSLGRVAARALADAGARLTLAGGNSAGLAELVNGAGIDDAAVVTCRPDS
LADAQQMVEAALGRYGRLDGVLVASGSNHVAPITEMAVEDFDAVMDANVRGAWLVCRAAGRVLLEQGQGGSVVLVSSVRG
GLGNAAGYSAYCPSKAGTDLLAKTLAAEWGGHGIRVNALAPTVFRSAVTEWMFTDDPKGRATREAMLARIPLRRFAEPED
FVGALIYLLSDASSFYTGQVMYLDGGYTAC

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=34.5381526104418, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI32483357, Length=257, Percent_Identity=30.7392996108949, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=31.4285714285714, Blast_Score=101, Evalue=5e-22,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=24.9027237354086, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI126723750, Length=258, Percent_Identity=28.6821705426357, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=28.6852589641434, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI66933014, Length=246, Percent_Identity=27.2357723577236, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI59889578, Length=230, Percent_Identity=28.695652173913, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI10190704, Length=256, Percent_Identity=28.90625, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4503301, Length=184, Percent_Identity=27.1739130434783, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4504505, Length=189, Percent_Identity=30.6878306878307, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI5031737, Length=252, Percent_Identity=25.3968253968254, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=33.4645669291339, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=26.984126984127, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1789208, Length=265, Percent_Identity=27.1698113207547, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=25.6916996047431, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1788459, Length=199, Percent_Identity=29.6482412060301, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=24.8995983935743, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=31.7269076305221, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787526, Length=249, Percent_Identity=28.9156626506024, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786812, Length=259, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1789057, Length=178, Percent_Identity=25.8426966292135, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=24.390243902439, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=24.8995983935743, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=255, Percent_Identity=30.1960784313725, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=30.8943089430894, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=30.7692307692308, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=27.6264591439689, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17555706, Length=265, Percent_Identity=30.188679245283, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=269, Percent_Identity=28.996282527881, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=28.0898876404494, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=267, Percent_Identity=27.3408239700375, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=268, Percent_Identity=28.7313432835821, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=275, Percent_Identity=28.7272727272727, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=26.1224489795918, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=25.6603773584906, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=25.4826254826255, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=25.187969924812, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=271, Percent_Identity=28.0442804428044, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=268, Percent_Identity=25, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=27.2388059701493, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=269, Percent_Identity=25.6505576208178, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=27.6119402985075, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=190, Percent_Identity=27.3684210526316, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=258, Percent_Identity=23.2558139534884, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=251, Percent_Identity=27.8884462151394, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322861, Length=202, Percent_Identity=31.1881188118812, Blast_Score=82, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=34.1463414634146, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=30.1204819277108, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=31.8897637795276, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21355319, Length=263, Percent_Identity=28.5171102661597, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=31.8897637795276, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=27.6, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=29.6, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24644337, Length=262, Percent_Identity=30.5343511450382, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27986; Mature: 27986

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEMALAQQVPNLGLARFSVQDKSILITGATGSLGRVAARALADAGARLTLAGGNSAGLA
CCHHHHHHHCCCCCEEEEEECCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCHH
ELVNGAGIDDAAVVTCRPDSLADAQQMVEAALGRYGRLDGVLVASGSNHVAPITEMAVED
HHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHH
FDAVMDANVRGAWLVCRAAGRVLLEQGQGGSVVLVSSVRGGLGNAAGYSAYCPSKAGTDL
HHHHHCCCCCCCEEEEEHHCHHEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHH
LAKTLAAEWGGHGIRVNALAPTVFRSAVTEWMFTDDPKGRATREAMLARIPLRRFAEPED
HHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHH
FVGALIYLLSDASSFYTGQVMYLDGGYTAC
HHHHHHHHHHCCCCHHCCEEEEECCCCCCC
>Mature Secondary Structure
MEEMALAQQVPNLGLARFSVQDKSILITGATGSLGRVAARALADAGARLTLAGGNSAGLA
CCHHHHHHHCCCCCEEEEEECCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCHH
ELVNGAGIDDAAVVTCRPDSLADAQQMVEAALGRYGRLDGVLVASGSNHVAPITEMAVED
HHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHH
FDAVMDANVRGAWLVCRAAGRVLLEQGQGGSVVLVSSVRGGLGNAAGYSAYCPSKAGTDL
HHHHHCCCCCCCEEEEEHHCHHEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHH
LAKTLAAEWGGHGIRVNALAPTVFRSAVTEWMFTDDPKGRATREAMLARIPLRRFAEPED
HHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHH
FVGALIYLLSDASSFYTGQVMYLDGGYTAC
HHHHHHHHHHCCCCHHCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]