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The map label for this gene is cmk

Identifier: 121637620

GI number: 121637620

Start: 1944816

End: 1945508

Strand: Direct

Name: cmk

Synonym: BCG_1751

Alternate gene names: 121637620

Gene position: 1944816-1945508 (Clockwise)

Preceding gene: 121637619

Following gene: 121637621

Centisome position: 44.46

GC content: 65.95

Gene sequence:

>693_bases
GTGAGTCGCCTAAGCGCAGCGGTAGTCGCGATCGACGGGCCGGCCGGCACCGGAAAATCCTCGGTGTCAAGGCGATTAGC
GCGCGAGCTGGGCGCACGCTTTCTGGACACCGGGGCAATGTATCGGATCGTGACGTTGGCGGTGCTGCGTGCCGGTGCTG
ATCCGTCCGATATCGCTGCCGTCGAGACGATTGCGTCGACGGTGCAGATGTCGTTAGGCTACGATCCCGACGGAGACAGC
TGTTACCTTGCCGGAGAAGACGTTTCGGTTGAGATACGCGGTGACGCGGTCACCCGTGCGGTCTCCGCGGTGTCGTCGGT
GCCGGCCGTACGCACCCGGCTGGTCGAGCTGCAGCGAACAATGGCTGAGGGCCCGGGCAGCATCGTCGTGGAGGGCCGCG
ACATCGGAACCGTGGTGTTTCCGGATGCGCCGGTGAAAATCTTCTTGACCGCCTCGGCCGAAACGCGGGCCCGGCGGCGC
AACGCCCAAAACGTCGCGGCGGGTTTGGCCGACGACTATGACGGGGTATTGGCCGATGTGCGCCGGCGCGACCACCTCGA
TTCCACCCGGGCGGTGTCACCGCTGCAAGCCGCCGGTGATGCCGTCATCGTGGACACCAGCGATATGACCGAGGCCGAGG
TGGTCGCCCATCTGTTGGAGCTGGTCACGCGGCGAAGTGAGGCAGTGCGGTGA

Upstream 100 bases:

>100_bases
GTACCGATATCGGCGCGGTGTCACTGGGAAAGCAACGCCCGGGCAGCGTTCGGGCCTTGCGGTCGAACGAGATCGGGCAA
CTGTACCAAGCGGTGGGCCT

Downstream 100 bases:

>100_bases
CCCAGGACGGCACGTGGGTGGACGAAAGCGATTGGCAACTAGACGATTCGGAGATCGCGGAGTCCGGAGCGGCGCCTGTG
GTGGCGGTAGTCGGCCGGCC

Product: cytidylate kinase

Products: NA

Alternate protein names: CK; Cytidine monophosphate kinase; CMP kinase

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MSRLSAAVVAIDGPAGTGKSSVSRRLARELGARFLDTGAMYRIVTLAVLRAGADPSDIAAVETIASTVQMSLGYDPDGDS
CYLAGEDVSVEIRGDAVTRAVSAVSSVPAVRTRLVELQRTMAEGPGSIVVEGRDIGTVVFPDAPVKIFLTASAETRARRR
NAQNVAAGLADDYDGVLADVRRRDHLDSTRAVSPLQAAGDAVIVDTSDMTEAEVVAHLLELVTRRSEAVR

Sequences:

>Translated_230_residues
MSRLSAAVVAIDGPAGTGKSSVSRRLARELGARFLDTGAMYRIVTLAVLRAGADPSDIAAVETIASTVQMSLGYDPDGDS
CYLAGEDVSVEIRGDAVTRAVSAVSSVPAVRTRLVELQRTMAEGPGSIVVEGRDIGTVVFPDAPVKIFLTASAETRARRR
NAQNVAAGLADDYDGVLADVRRRDHLDSTRAVSPLQAAGDAVIVDTSDMTEAEVVAHLLELVTRRSEAVR
>Mature_229_residues
SRLSAAVVAIDGPAGTGKSSVSRRLARELGARFLDTGAMYRIVTLAVLRAGADPSDIAAVETIASTVQMSLGYDPDGDSC
YLAGEDVSVEIRGDAVTRAVSAVSSVPAVRTRLVELQRTMAEGPGSIVVEGRDIGTVVFPDAPVKIFLTASAETRARRRN
AQNVAAGLADDYDGVLADVRRRDHLDSTRAVSPLQAAGDAVIVDTSDMTEAEVVAHLLELVTRRSEAVR

Specific function: ATP, Datp, And GTP Are Equally Effective As Phosphate Donors. CMP And Dcmp Are The Best Phosphate Acceptors. [C]

COG id: COG0283

COG function: function code F; Cytidylate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylate kinase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1787139, Length=220, Percent_Identity=40, Blast_Score=157, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KCY_MYCBO (P63804)

Other databases:

- EMBL:   BX248340
- RefSeq:   NP_855392.1
- ProteinModelPortal:   P63804
- SMR:   P63804
- EnsemblBacteria:   EBMYCT00000015513
- GeneID:   1092704
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1739
- GeneTree:   EBGT00050000015811
- HOGENOM:   HBG354377
- OMA:   DIGTVIC
- ProtClustDB:   PRK00023
- BioCyc:   MBOV233413:MB1739-MONOMER
- BRENDA:   2.7.4.14
- GO:   GO:0005737
- HAMAP:   MF_00238
- InterPro:   IPR003136
- InterPro:   IPR011994
- PANTHER:   PTHR21299:SF2
- TIGRFAMs:   TIGR00017

Pfam domain/function: PF02224 Cytidylate_kin

EC number: =2.7.4.14

Molecular weight: Translated: 24178; Mature: 24046

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLSAAVVAIDGPAGTGKSSVSRRLARELGARFLDTGAMYRIVTLAVLRAGADPSDIAA
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHH
VETIASTVQMSLGYDPDGDSCYLAGEDVSVEIRGDAVTRAVSAVSSVPAVRTRLVELQRT
HHHHHHHHHHHCCCCCCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
MAEGPGSIVVEGRDIGTVVFPDAPVKIFLTASAETRARRRNAQNVAAGLADDYDGVLADV
HHCCCCEEEEECCCCCEEEECCCCEEEEEECCHHHHHHHHCHHHHHHCCCCCHHHHHHHH
RRRDHLDSTRAVSPLQAAGDAVIVDTSDMTEAEVVAHLLELVTRRSEAVR
HHHHCCCHHHCCCCHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRLSAAVVAIDGPAGTGKSSVSRRLARELGARFLDTGAMYRIVTLAVLRAGADPSDIAA
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHH
VETIASTVQMSLGYDPDGDSCYLAGEDVSVEIRGDAVTRAVSAVSSVPAVRTRLVELQRT
HHHHHHHHHHHCCCCCCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
MAEGPGSIVVEGRDIGTVVFPDAPVKIFLTASAETRARRRNAQNVAAGLADDYDGVLADV
HHCCCCEEEEECCCCCEEEECCCCEEEEEECCHHHHHHHHCHHHHHHCCCCCHHHHHHHH
RRRDHLDSTRAVSPLQAAGDAVIVDTSDMTEAEVVAHLLELVTRRSEAVR
HHHHCCCHHHCCCCHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972