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The map label for this gene is argJ

Identifier: 121637561

GI number: 121637561

Start: 1871898

End: 1873112

Strand: Direct

Name: argJ

Synonym: BCG_1692

Alternate gene names: 121637561

Gene position: 1871898-1873112 (Clockwise)

Preceding gene: 121637560

Following gene: 121637562

Centisome position: 42.79

GC content: 71.19

Gene sequence:

>1215_bases
GTGACCGACCTGGCCGGCACCACCCGGCTGCTGCGCGCTCAGGGCGTCACCGCCCCGGCCGGCTTTCGGGCCGCCGGCGT
CGCCGCCGGGATCAAGGCCTCCGGTGCGCTGGATCTGGCGCTGGTGTTCAACGAGGGACCCGACTACGCCGCCGCCGGGG
TGTTCACCCGCAACCAGGTCAAGGCGGCGCCGGTGCTGTGGACCCAGCAAGTGCTGACCACCGGGCGGCTGCGCGCGGTG
ATCCTCAACTCCGGCGGCGCCAATGCCTGCACCGGGCCGGCCGGCTTCGCCGACACCCACGCCACCGCGGAGGCGGTGGC
CGCGGCGTTGTCGGACTGGGGAACCGAGACCGGGGCCATCGAGGTCGCCGTCTGCTCCACCGGGCTGATCGGCGACCGGC
TGCCGATGGACAAGCTGCTCGCCGGCGTCGCCCACGTGGTGCACGAGATGCATGGCGGGCTGGTCGGCGGCGATGAAGCC
GCCCACGCCATCATGACCACCGACAACGTGCCCAAACAGGTTGCGCTGCACCATCACGACAACTGGACGGTCGGCGGCAT
GGCCAAAGGCGCGGGCATGCTGGCGCCGTCGTTGGCCACCATGCTGTGCGTGCTCACCACCGACGCGGCCGCCGAGCCGG
CCGCACTCGAGCGGGCGCTGCGCCGCGCCGCCGCGGCCACGTTCGACCGGCTCGACATCGACGGCAGCTGCTCCACCAAC
GACACCGTGCTGCTGCTGTCGTCCGGGGCCAGTGAAATCCCCCCTGCCCAGGCCGATCTCGACGAGGCCGTGCTACGGGT
CTGCGACGATTTGTGCGCCCAGCTGCAGGCCGACGCCGAAGGCGTCACCAAACGCGTCACCGTGACCGTGACCGGGGCCG
CCACCGAAGACGACGCGCTGGTCGCCGCCCGCCAGATCGCCCGCGACAGCCTGGTCAAGACCGCGCTGTTCGGGTCCGAC
CCGAACTGGGGACGGGTGCTCGCCGCCGTCGGGATGGCACCGATCACCCTCGACCCGGATCGAATCAGCGTGTCGTTCAA
CGGTGCCGCGGTGTGTGTGCACGGTGTCGGCGCTCCCGGTGCGCGCGAGGTGGACCTGTCGGACGCGGACATCGATATCA
CCGTCGACCTCGGCGTCGGCGACGGGCAGGCGAGGATCCGAACCACTGATCTGTCGCATGCCTACGTCGAAGAGAACTCG
GCCTACAGCTCATGA

Upstream 100 bases:

>100_bases
ACAACCTGGTCAAGGGCACCGCCGGCGCCGCGGTGCAATCGATGAACCTGGCGCTGGGCTGGCCGGAGACCGACGGCCTT
TCGGTTGTGGGGGTGGCGCC

Downstream 100 bases:

>100_bases
GCCGCATCGAAGCACTGCCCACCCACATCAAAGCGCAGGTGCTGGCCGAGGCCCTGCCCTGGCTCAAGCAGTTGCACGGC
AAGGTCGTCGTCGTCAAATA

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTDLAGTTRLLRAQGVTAPAGFRAAGVAAGIKASGALDLALVFNEGPDYAAAGVFTRNQVKAAPVLWTQQVLTTGRLRAV
ILNSGGANACTGPAGFADTHATAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKLLAGVAHVVHEMHGGLVGGDEA
AHAIMTTDNVPKQVALHHHDNWTVGGMAKGAGMLAPSLATMLCVLTTDAAAEPAALERALRRAAAATFDRLDIDGSCSTN
DTVLLLSSGASEIPPAQADLDEAVLRVCDDLCAQLQADAEGVTKRVTVTVTGAATEDDALVAARQIARDSLVKTALFGSD
PNWGRVLAAVGMAPITLDPDRISVSFNGAAVCVHGVGAPGAREVDLSDADIDITVDLGVGDGQARIRTTDLSHAYVEENS
AYSS

Sequences:

>Translated_404_residues
MTDLAGTTRLLRAQGVTAPAGFRAAGVAAGIKASGALDLALVFNEGPDYAAAGVFTRNQVKAAPVLWTQQVLTTGRLRAV
ILNSGGANACTGPAGFADTHATAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKLLAGVAHVVHEMHGGLVGGDEA
AHAIMTTDNVPKQVALHHHDNWTVGGMAKGAGMLAPSLATMLCVLTTDAAAEPAALERALRRAAAATFDRLDIDGSCSTN
DTVLLLSSGASEIPPAQADLDEAVLRVCDDLCAQLQADAEGVTKRVTVTVTGAATEDDALVAARQIARDSLVKTALFGSD
PNWGRVLAAVGMAPITLDPDRISVSFNGAAVCVHGVGAPGAREVDLSDADIDITVDLGVGDGQARIRTTDLSHAYVEENS
AYSS
>Mature_403_residues
TDLAGTTRLLRAQGVTAPAGFRAAGVAAGIKASGALDLALVFNEGPDYAAAGVFTRNQVKAAPVLWTQQVLTTGRLRAVI
LNSGGANACTGPAGFADTHATAEAVAAALSDWGTETGAIEVAVCSTGLIGDRLPMDKLLAGVAHVVHEMHGGLVGGDEAA
HAIMTTDNVPKQVALHHHDNWTVGGMAKGAGMLAPSLATMLCVLTTDAAAEPAALERALRRAAAATFDRLDIDGSCSTND
TVLLLSSGASEIPPAQADLDEAVLRVCDDLCAQLQADAEGVTKRVTVTVTGAATEDDALVAARQIARDSLVKTALFGSDP
NWGRVLAAVGMAPITLDPDRISVSFNGAAVCVHGVGAPGAREVDLSDADIDITVDLGVGDGQARIRTTDLSHAYVEENSA
YSS

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=420, Percent_Identity=38.5714285714286, Blast_Score=238, Evalue=1e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGJ_MYCBO (P63572)

Other databases:

- EMBL:   BX248339
- RefSeq:   NP_855333.1
- ProteinModelPortal:   P63572
- SMR:   P63572
- MEROPS:   T05.001
- EnsemblBacteria:   EBMYCT00000016967
- GeneID:   1092623
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1681
- GeneTree:   EBGT00050000016724
- HOGENOM:   HBG284202
- OMA:   VHENSAY
- ProtClustDB:   PRK05388
- BioCyc:   MBOV233413:MB1681-MONOMER
- BRENDA:   2.3.1.1
- BRENDA:   2.3.1.35
- GO:   GO:0005737
- HAMAP:   MF_01106
- InterPro:   IPR002813
- InterPro:   IPR016117
- PANTHER:   PTHR23100
- TIGRFAMs:   TIGR00120

Pfam domain/function: PF01960 ArgJ; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: =2.3.1.35; =2.3.1.1

Molecular weight: Translated: 41148; Mature: 41016

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLAGTTRLLRAQGVTAPAGFRAAGVAAGIKASGALDLALVFNEGPDYAAAGVFTRNQV
CCCCHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCEEEEEEEECCCCCCEECCEECCCC
KAAPVLWTQQVLTTGRLRAVILNSGGANACTGPAGFADTHATAEAVAAALSDWGTETGAI
CCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEE
EVAVCSTGLIGDRLPMDKLLAGVAHVVHEMHGGLVGGDEAAHAIMTTDNVPKQVALHHHD
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHCEEEEECCCCCCEEEEEECC
NWTVGGMAKGAGMLAPSLATMLCVLTTDAAAEPAALERALRRAAAATFDRLDIDGSCSTN
CEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DTVLLLSSGASEIPPAQADLDEAVLRVCDDLCAQLQADAEGVTKRVTVTVTGAATEDDAL
CEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCHHH
VAARQIARDSLVKTALFGSDPNWGRVLAAVGMAPITLDPDRISVSFNGAAVCVHGVGAPG
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEECCCEEEEEECCEEEEEEECCCCC
AREVDLSDADIDITVDLGVGDGQARIRTTDLSHAYVEENSAYSS
CCEEECCCCCEEEEEEECCCCCCCEEEEECCCCCEECCCCCCCC
>Mature Secondary Structure 
TDLAGTTRLLRAQGVTAPAGFRAAGVAAGIKASGALDLALVFNEGPDYAAAGVFTRNQV
CCCHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCEEEEEEEECCCCCCEECCEECCCC
KAAPVLWTQQVLTTGRLRAVILNSGGANACTGPAGFADTHATAEAVAAALSDWGTETGAI
CCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEE
EVAVCSTGLIGDRLPMDKLLAGVAHVVHEMHGGLVGGDEAAHAIMTTDNVPKQVALHHHD
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHCEEEEECCCCCCEEEEEECC
NWTVGGMAKGAGMLAPSLATMLCVLTTDAAAEPAALERALRRAAAATFDRLDIDGSCSTN
CEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DTVLLLSSGASEIPPAQADLDEAVLRVCDDLCAQLQADAEGVTKRVTVTVTGAATEDDAL
CEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCHHH
VAARQIARDSLVKTALFGSDPNWGRVLAAVGMAPITLDPDRISVSFNGAAVCVHGVGAPG
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEECCCEEEEEECCEEEEEEECCCCC
AREVDLSDADIDITVDLGVGDGQARIRTTDLSHAYVEENSAYSS
CCEEECCCCCEEEEEEECCCCCCCEEEEECCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972