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The map label for this gene is infC [H]

Identifier: 121637549

GI number: 121637549

Start: 1857519

End: 1858124

Strand: Direct

Name: infC [H]

Synonym: BCG_1680

Alternate gene names: 121637549

Gene position: 1857519-1858124 (Clockwise)

Preceding gene: 121637545

Following gene: 121637550

Centisome position: 42.46

GC content: 61.88

Gene sequence:

>606_bases
ATCAGCACTGAAACCCGCGTCAACGAGCGCATCCGCGTACCTGAAGTCCGATTGATCGGCCCAGGGGGGGAGCAGGTAGG
CATTGTGCGTATCGAAGACTCACTTCGCGTCGCCGCGGACGCAGATCTCGACCTTGTCGAAGTTGCTCCCAATGCCAGAC
CGCCGGTCTGCAAGATCATGGACTACGGCAAGTACAAGTACGAGGCCGCGCAGAAGGCGCGCGAATCCCGCAGAAACCAA
CAGCAGACCGTCGTCAAAGAACAAAAGCTGCGACCAAAGATTGACGATCACGATTACGAGACCAAAAAGGGTCACGTCGT
CCGCTTCTTGGAGGCGGGATCGAAGGTCAAGGTCACCATTATGTTCCGTGGACGTGAGCAGTCGCGGCCGGAGTTGGGCT
ATCGATTGCTGCAGCGGCTGGGTGCGGACGTCGCCGATTACGGATTCATCGAGACGTCCGCCAAGCAGGACGGACGCAAC
ATGACGATGGTGCTGGCACCGCACCGCGGTGCGAAGACCCGCGCTAGGGCCCGCCACCCGGGTGAACCGGCCGGCGGGCC
GCCGCCCAAGCCCACGGCCGGTGACAGCAAAGCCGCACCGAACTAG

Upstream 100 bases:

>100_bases
AGGGCTTTTTTGCTGATGGTTTGGGTGTGTTCCCCACCTGATTCCGGCCGGGTCCAACAAGCTGGTCGCGCCTGGAACAG
CAGCCAACGAGGGAGGCCCC

Downstream 100 bases:

>100_bases
CTCGCCAGCAAGACACGCAGAACCTAGAAATTCTAGAAATTGAGGAAACATGCCCAAGGCCAAGACCCACAGCGGGGCCT
CGAAGCGGTTCCGGCGCACC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MSTETRVNERIRVPEVRLIGPGGEQVGIVRIEDSLRVAADADLDLVEVAPNARPPVCKIMDYGKYKYEAAQKARESRRNQ
QQTVVKEQKLRPKIDDHDYETKKGHVVRFLEAGSKVKVTIMFRGREQSRPELGYRLLQRLGADVADYGFIETSAKQDGRN
MTMVLAPHRGAKTRARARHPGEPAGGPPPKPTAGDSKAAPN

Sequences:

>Translated_201_residues
MSTETRVNERIRVPEVRLIGPGGEQVGIVRIEDSLRVAADADLDLVEVAPNARPPVCKIMDYGKYKYEAAQKARESRRNQ
QQTVVKEQKLRPKIDDHDYETKKGHVVRFLEAGSKVKVTIMFRGREQSRPELGYRLLQRLGADVADYGFIETSAKQDGRN
MTMVLAPHRGAKTRARARHPGEPAGGPPPKPTAGDSKAAPN
>Mature_200_residues
STETRVNERIRVPEVRLIGPGGEQVGIVRIEDSLRVAADADLDLVEVAPNARPPVCKIMDYGKYKYEAAQKARESRRNQQ
QTVVKEQKLRPKIDDHDYETKKGHVVRFLEAGSKVKVTIMFRGREQSRPELGYRLLQRLGADVADYGFIETSAKQDGRNM
TMVLAPHRGAKTRARARHPGEPAGGPPPKPTAGDSKAAPN

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=166, Percent_Identity=45.7831325301205, Blast_Score=144, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 22350; Mature: 22219

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTETRVNERIRVPEVRLIGPGGEQVGIVRIEDSLRVAADADLDLVEVAPNARPPVCKIM
CCCCCCCCCEECCCEEEEECCCCCEEEEEEECCCEEEECCCCCEEEEECCCCCCCEEEEE
DYGKYKYEAAQKARESRRNQQQTVVKEQKLRPKIDDHDYETKKGHVVRFLEAGSKVKVTI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEE
MFRGREQSRPELGYRLLQRLGADVADYGFIETSAKQDGRNMTMVLAPHRGAKTRARARHP
EECCCCCCCHHHHHHHHHHHCCCHHHCCEEECCCCCCCCCEEEEEECCCCCCCHHHCCCC
GEPAGGPPPKPTAGDSKAAPN
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
STETRVNERIRVPEVRLIGPGGEQVGIVRIEDSLRVAADADLDLVEVAPNARPPVCKIM
CCCCCCCCEECCCEEEEECCCCCEEEEEEECCCEEEECCCCCEEEEECCCCCCCEEEEE
DYGKYKYEAAQKARESRRNQQQTVVKEQKLRPKIDDHDYETKKGHVVRFLEAGSKVKVTI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEE
MFRGREQSRPELGYRLLQRLGADVADYGFIETSAKQDGRNMTMVLAPHRGAKTRARARHP
EECCCCCCCHHHHHHHHHHHCCCHHHCCEEECCCCCCCCCEEEEEECCCCCCCHHHCCCC
GEPAGGPPPKPTAGDSKAAPN
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]