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The map label for this gene is yqjQ [H]

Identifier: 121637466

GI number: 121637466

Start: 1758533

End: 1759228

Strand: Direct

Name: yqjQ [H]

Synonym: BCG_1597

Alternate gene names: 121637466

Gene position: 1758533-1759228 (Clockwise)

Preceding gene: 121637465

Following gene: 121637467

Centisome position: 40.2

GC content: 65.66

Gene sequence:

>696_bases
ATGCTAGTGGCGCGGCGCCGCGAGCGCCTCGACGAACTGGCCGATCAGCTGCGCCAGGAACACTGCGTCGGGGTGGAGGT
CTTGCCGCTCGACCTTGCCGATACGCAAGCGAGGGCACAGCTGGCTGATCGCTTGCGTAGTGATGCGATTGCCGGGCTGT
GCAACAGCGCAGGTTTCGGCACCAGTGGGCGTTTTTGGGAGTTGCCGTTCGCACGCGAAAGCGAGGAAGTCGTCCTCAAT
GCTCTGGCGTTAATGGAACTCACCCATGCCGCACTGCCAGGCATGGTCAAGCGCGGCGCCGGTGCGGTGCTCAACATCGC
CTCGATCGCGGGTTTCCAGCCGATTCCCTATATGGCCGTGTATTCGGCTACCAAAGCCTTTGTGCTGACGTTCTCTGAAG
CCGTGCAGGAGGAGCTGCACGGAACGGGCGTGTCGGTGACTGCCCTGTGCCCAGGCCCGGTACCCACCGAGTGGGCCGAG
ATCGCCAGCGCCGAGCGGTTCAGCATTCCCCTCGCCCAAGTTTCGCCGCACGACGTCGCCGAAGCCGCCATCGCCGGGAT
GCTCTCCGGTAAGCGCACCGTCGTGCCGGGCATAGTGCCAAAGTTCGTCAGCACCAGCGGCAGATTCGCTCCGCGCAGCC
TGCTGCTGCCCGCGATCCGGATCGGCAACCGGCTGCGCGGCGGGCCCAGCCGCTGA

Upstream 100 bases:

>100_bases
CCATGAGCCTTCCGAAACCGAACAATCAGACCACCGTTGTGATCACCGGCGCCTCGGTGTCGAATTGGCTCGTGGCTTGG
CCGGCCGCGGCTTCCCACTG

Downstream 100 bases:

>100_bases
TGTGAGGGGCGTTCCGGCCTGGTGCCGAACGGAGTGCTGGGCCTGGGCAATCCCAGCCGGCTAGCCGCGTTGTATGGGTT
GCAGCTGGCGCACGAGTCGC

Product: putative ketoacyl reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MLVARRRERLDELADQLRQEHCVGVEVLPLDLADTQARAQLADRLRSDAIAGLCNSAGFGTSGRFWELPFARESEEVVLN
ALALMELTHAALPGMVKRGAGAVLNIASIAGFQPIPYMAVYSATKAFVLTFSEAVQEELHGTGVSVTALCPGPVPTEWAE
IASAERFSIPLAQVSPHDVAEAAIAGMLSGKRTVVPGIVPKFVSTSGRFAPRSLLLPAIRIGNRLRGGPSR

Sequences:

>Translated_231_residues
MLVARRRERLDELADQLRQEHCVGVEVLPLDLADTQARAQLADRLRSDAIAGLCNSAGFGTSGRFWELPFARESEEVVLN
ALALMELTHAALPGMVKRGAGAVLNIASIAGFQPIPYMAVYSATKAFVLTFSEAVQEELHGTGVSVTALCPGPVPTEWAE
IASAERFSIPLAQVSPHDVAEAAIAGMLSGKRTVVPGIVPKFVSTSGRFAPRSLLLPAIRIGNRLRGGPSR
>Mature_231_residues
MLVARRRERLDELADQLRQEHCVGVEVLPLDLADTQARAQLADRLRSDAIAGLCNSAGFGTSGRFWELPFARESEEVVLN
ALALMELTHAALPGMVKRGAGAVLNIASIAGFQPIPYMAVYSATKAFVLTFSEAVQEELHGTGVSVTALCPGPVPTEWAE
IASAERFSIPLAQVSPHDVAEAAIAGMLSGKRTVVPGIVPKFVSTSGRFAPRSLLLPAIRIGNRLRGGPSR

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705855, Length=165, Percent_Identity=30.9090909090909, Blast_Score=94, Evalue=7e-20,
Organism=Homo sapiens, GI226371731, Length=164, Percent_Identity=28.6585365853659, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1787820, Length=192, Percent_Identity=34.8958333333333, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1786701, Length=216, Percent_Identity=24.537037037037, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=163, Percent_Identity=30.6748466257669, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24640442, Length=179, Percent_Identity=29.608938547486, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24584744, Length=164, Percent_Identity=27.4390243902439, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28574402, Length=164, Percent_Identity=27.4390243902439, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21358495, Length=162, Percent_Identity=28.3950617283951, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24608; Mature: 24608

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVARRRERLDELADQLRQEHCVGVEVLPLDLADTQARAQLADRLRSDAIAGLCNSAGFG
CCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
TSGRFWELPFARESEEVVLNALALMELTHAALPGMVKRGAGAVLNIASIAGFQPIPYMAV
CCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCCHHHH
YSATKAFVLTFSEAVQEELHGTGVSVTALCPGPVPTEWAEIASAERFSIPLAQVSPHDVA
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHCCHHHCCCHHHCCCHHHH
EAAIAGMLSGKRTVVPGIVPKFVSTSGRFAPRSLLLPAIRIGNRLRGGPSR
HHHHHHHHCCCCEECCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLVARRRERLDELADQLRQEHCVGVEVLPLDLADTQARAQLADRLRSDAIAGLCNSAGFG
CCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
TSGRFWELPFARESEEVVLNALALMELTHAALPGMVKRGAGAVLNIASIAGFQPIPYMAV
CCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCCHHHH
YSATKAFVLTFSEAVQEELHGTGVSVTALCPGPVPTEWAEIASAERFSIPLAQVSPHDVA
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHCCHHHCCCHHHCCCHHHH
EAAIAGMLSGKRTVVPGIVPKFVSTSGRFAPRSLLLPAIRIGNRLRGGPSR
HHHHHHHHCCCCEECCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]