BacMap

Definition	Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome.
Accession	NC_008769
Length	4,374,522

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The map label for this gene is ydfG [C]

Identifier: 121637464

GI number: 121637464

Start: 1757405

End: 1758430

Strand: Direct

Name: ydfG [C]

Synonym: BCG_1595

Alternate gene names: 121637464

Gene position: 1757405-1758430 (Clockwise)

Preceding gene: 121637461

Following gene: 121637465

Centisome position: 40.17

GC content: 61.5

Gene sequence:

>1026_bases
ATGAATCTTGGTGACTTAACGAACTTCGTCGAGAAGCCGCTCGCGGCGGTGTCCAACATCGTCAACACCCCGAACTCGGC
CGGGCGATATCGGCCCTTCTACTTGCGCAACTTGCTCGATGCGGTGCAGGGCCGCAACCTCAATGATGCTGTCAAGGGCA
AGGTTGTCCTCATCACTGGTGGGTCATCAGGCATCGGTGCGGCGGCCGCGAAGAAAATTGCCGAGGCCGGCGGCACGGTG
GTGTTGGTCGCACGCACCCTGGAAAACCTCGAGAACGTCGCCAACGACATACGGGCGATCCGAGGCAACGGTGGGACCGC
CCACGTCTACCCGTGCGATCTATCCGACATGGATGCGATTGCCGTGATGGCCGACCAGGTGCTCGGCGACCTCGGCGGCG
TCGACATCTTGATCAACAACGCGGGCCGGTCAATTCGGCGCTCGTTGGAGTTGTCCTATGACCGGATCCACGATTACCAG
CGAACGATGCAGCTCAACTACCTCGGCGCGGTCCAGCTGATCCTGAAGTTCATCCCCGGAATGCGAGAACGCCACTTCGG
GCATATCGTCAACGTTTCCTCAGTCGGCGTGCAGACCCGCGCGCCGCGCTTCGGCGCTTACATCGCCAGCAAGGCCGCGC
TGGACAGCCTGTGTGATGCGTTGCAAGCCGAGACCGTGCACGACAACGTCCGATTCACCACCGTGCACATGGCATTGGTA
AGGACTCCAATGATCAGCCCGACCACGATCTACGACAAGTTTCCCACGCTGACGCCGGATCAGGCGGCCGGTGTGATCAC
CGATGCCATCGTGCATCGGCCCCGGCGAGCCAGCTCACCGTTCGGACAGTTCGCCGCCGTTGCCGACGCCGTCAACCCCG
CGGTGATGGACCGGGTACGTAACCGTGCCTTCAACATGTTCGGCGACTCGTCCGCAGCCAAGGGAAGTGAATCCCAAACC
GACACATCAGAACTCGACAAGCGAAGCGAGACGTTTGTGCGGGCCACCCGAGGGATCCATTGGTGA

Upstream 100 bases:

>100_bases
CACCGGCCGGTAGTGGACTCCATTCATCAGCTCATGTGCTAGTAGGTTGGCTTCATGACCCGTGTCCATCACCCCACGCC
GCCATCAGGAGCTACCCACG

Downstream 100 bases:

>100_bases
CACCATGAGCCTTCCGAAACCGAACAATCAGACCACCGTTGTGATCACCGGCGCCTCGGTGTCGAATTGGCTCGTGGCTT
GGCCGGCCGCGGCTTCCCAC

Product: putative fatty acyl-CoA reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MNLGDLTNFVEKPLAAVSNIVNTPNSAGRYRPFYLRNLLDAVQGRNLNDAVKGKVVLITGGSSGIGAAAAKKIAEAGGTV
VLVARTLENLENVANDIRAIRGNGGTAHVYPCDLSDMDAIAVMADQVLGDLGGVDILINNAGRSIRRSLELSYDRIHDYQ
RTMQLNYLGAVQLILKFIPGMRERHFGHIVNVSSVGVQTRAPRFGAYIASKAALDSLCDALQAETVHDNVRFTTVHMALV
RTPMISPTTIYDKFPTLTPDQAAGVITDAIVHRPRRASSPFGQFAAVADAVNPAVMDRVRNRAFNMFGDSSAAKGSESQT
DTSELDKRSETFVRATRGIHW

Sequences:

>Translated_341_residues
MNLGDLTNFVEKPLAAVSNIVNTPNSAGRYRPFYLRNLLDAVQGRNLNDAVKGKVVLITGGSSGIGAAAAKKIAEAGGTV
VLVARTLENLENVANDIRAIRGNGGTAHVYPCDLSDMDAIAVMADQVLGDLGGVDILINNAGRSIRRSLELSYDRIHDYQ
RTMQLNYLGAVQLILKFIPGMRERHFGHIVNVSSVGVQTRAPRFGAYIASKAALDSLCDALQAETVHDNVRFTTVHMALV
RTPMISPTTIYDKFPTLTPDQAAGVITDAIVHRPRRASSPFGQFAAVADAVNPAVMDRVRNRAFNMFGDSSAAKGSESQT
DTSELDKRSETFVRATRGIHW
>Mature_341_residues
MNLGDLTNFVEKPLAAVSNIVNTPNSAGRYRPFYLRNLLDAVQGRNLNDAVKGKVVLITGGSSGIGAAAAKKIAEAGGTV
VLVARTLENLENVANDIRAIRGNGGTAHVYPCDLSDMDAIAVMADQVLGDLGGVDILINNAGRSIRRSLELSYDRIHDYQ
RTMQLNYLGAVQLILKFIPGMRERHFGHIVNVSSVGVQTRAPRFGAYIASKAALDSLCDALQAETVHDNVRFTTVHMALV
RTPMISPTTIYDKFPTLTPDQAAGVITDAIVHRPRRASSPFGQFAAVADAVNPAVMDRVRNRAFNMFGDSSAAKGSESQT
DTSELDKRSETFVRATRGIHW

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family

Homologues:

Organism=Homo sapiens, GI20149619, Length=214, Percent_Identity=34.5794392523364, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI7706318, Length=192, Percent_Identity=36.4583333333333, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI157739938, Length=207, Percent_Identity=32.3671497584541, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4503817, Length=241, Percent_Identity=34.0248962655602, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI32455239, Length=196, Percent_Identity=32.1428571428571, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI5031765, Length=196, Percent_Identity=32.1428571428571, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI210032110, Length=271, Percent_Identity=26.1992619926199, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI142976729, Length=237, Percent_Identity=29.535864978903, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI40807363, Length=236, Percent_Identity=28.8135593220339, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI109715829, Length=209, Percent_Identity=31.5789473684211, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI226371731, Length=211, Percent_Identity=29.3838862559242, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI223718074, Length=208, Percent_Identity=30.2884615384615, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI19923817, Length=193, Percent_Identity=25.3886010362694, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI32483357, Length=207, Percent_Identity=26.0869565217391, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI126723191, Length=196, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI7657478, Length=188, Percent_Identity=32.9787234042553, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI7705925, Length=265, Percent_Identity=26.7924528301887, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI166795268, Length=144, Percent_Identity=34.7222222222222, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI25282469, Length=258, Percent_Identity=29.0697674418605, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4557649, Length=174, Percent_Identity=29.8850574712644, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI40254992, Length=192, Percent_Identity=30.2083333333333, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI225579078, Length=257, Percent_Identity=27.6264591439689, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787820, Length=187, Percent_Identity=25.668449197861, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082100, Length=241, Percent_Identity=30.2904564315353, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786701, Length=200, Percent_Identity=31.5, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787905, Length=150, Percent_Identity=28.6666666666667, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788459, Length=195, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI2367175, Length=193, Percent_Identity=30.0518134715026, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787526, Length=215, Percent_Identity=27.906976744186, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789378, Length=221, Percent_Identity=28.9592760180996, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=209, Percent_Identity=32.5358851674641, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17567345, Length=242, Percent_Identity=28.099173553719, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71997402, Length=234, Percent_Identity=31.6239316239316, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17570069, Length=277, Percent_Identity=30.3249097472924, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193203115, Length=284, Percent_Identity=28.5211267605634, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=267, Percent_Identity=27.7153558052434, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193203117, Length=262, Percent_Identity=29.0076335877863, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=195, Percent_Identity=31.2820512820513, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=192, Percent_Identity=32.2916666666667, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=231, Percent_Identity=30.7359307359307, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=212, Percent_Identity=30.6603773584906, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=195, Percent_Identity=31.2820512820513, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=192, Percent_Identity=31.7708333333333, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=195, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=221, Percent_Identity=28.9592760180996, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=224, Percent_Identity=29.0178571428571, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=26.865671641791, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17558006, Length=155, Percent_Identity=30.9677419354839, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=215, Percent_Identity=31.6279069767442, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=215, Percent_Identity=30.6976744186047, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=275, Percent_Identity=25.4545454545455, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=199, Percent_Identity=29.6482412060301, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=272, Percent_Identity=28.3088235294118, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=191, Percent_Identity=30.8900523560209, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=192, Percent_Identity=29.1666666666667, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=226, Percent_Identity=26.1061946902655, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17507613, Length=251, Percent_Identity=22.3107569721116, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=251, Percent_Identity=22.3107569721116, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=192, Percent_Identity=31.25, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=196, Percent_Identity=28.0612244897959, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=208, Percent_Identity=29.8076923076923, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6322227, Length=201, Percent_Identity=29.8507462686567, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21358495, Length=214, Percent_Identity=34.5794392523364, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281364892, Length=235, Percent_Identity=32.7659574468085, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI116007236, Length=223, Percent_Identity=33.6322869955157, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24640492, Length=229, Percent_Identity=31.0043668122271, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI116007238, Length=179, Percent_Identity=36.3128491620112, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21355631, Length=258, Percent_Identity=29.0697674418605, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28571526, Length=191, Percent_Identity=32.4607329842932, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI23397609, Length=202, Percent_Identity=33.6633663366337, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24641232, Length=236, Percent_Identity=27.9661016949153, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24643142, Length=195, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24580925, Length=183, Percent_Identity=34.9726775956284, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357041, Length=193, Percent_Identity=31.6062176165803, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24644339, Length=184, Percent_Identity=32.6086956521739, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28571387, Length=210, Percent_Identity=29.5238095238095, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24663911, Length=230, Percent_Identity=30.4347826086957, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24648944, Length=230, Percent_Identity=26.9565217391304, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355319, Length=195, Percent_Identity=27.1794871794872, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007234, Length=249, Percent_Identity=27.3092369477912, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24641388, Length=233, Percent_Identity=27.4678111587983, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24648693, Length=231, Percent_Identity=25.974025974026, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355889, Length=231, Percent_Identity=25.974025974026, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21357673, Length=248, Percent_Identity=25.4032258064516, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI221510726, Length=234, Percent_Identity=26.9230769230769, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): Y1543_MYCTU (P66779)

Other databases:

- EMBL:   BX842577
- EMBL:   AE000516
- PIR:   D70761
- RefSeq:   NP_216059.1
- RefSeq:   NP_336047.1
- ProteinModelPortal:   P66779
- SMR:   P66779
- EnsemblBacteria:   EBMYCT00000001676
- EnsemblBacteria:   EBMYCT00000069594
- GeneID:   886400
- GeneID:   924353
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1595
- KEGG:   mtu:Rv1543
- TIGR:   MT1595
- TubercuList:   Rv1543
- GeneTree:   EBGT00050000015153
- HOGENOM:   HBG750976
- OMA:   RTMAINY
- ProtClustDB:   CLSK791238
- GO:   GO:0005488
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR19410
- PRINTS:   PR00081
- PRINTS:   PR00080

Pfam domain/function: PF00106 adh_short

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36821; Mature: 36821

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS00061 ADH_SHORT

Important sites: ACT_SITE 207-207 BINDING 194-194

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLGDLTNFVEKPLAAVSNIVNTPNSAGRYRPFYLRNLLDAVQGRNLNDAVKGKVVLITG
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCEEEEEEC
GSSGIGAAAAKKIAEAGGTVVLVARTLENLENVANDIRAIRGNGGTAHVYPCDLSDMDAI
CCCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHH
AVMADQVLGDLGGVDILINNAGRSIRRSLELSYDRIHDYQRTMQLNYLGAVQLILKFIPG
HHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
MRERHFGHIVNVSSVGVQTRAPRFGAYIASKAALDSLCDALQAETVHDNVRFTTVHMALV
HHHHHCCCEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHH
RTPMISPTTIYDKFPTLTPDQAAGVITDAIVHRPRRASSPFGQFAAVADAVNPAVMDRVR
HCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHH
NRAFNMFGDSSAAKGSESQTDTSELDKRSETFVRATRGIHW
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNLGDLTNFVEKPLAAVSNIVNTPNSAGRYRPFYLRNLLDAVQGRNLNDAVKGKVVLITG
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCEEEEEEC
GSSGIGAAAAKKIAEAGGTVVLVARTLENLENVANDIRAIRGNGGTAHVYPCDLSDMDAI
CCCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHH
AVMADQVLGDLGGVDILINNAGRSIRRSLELSYDRIHDYQRTMQLNYLGAVQLILKFIPG
HHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
MRERHFGHIVNVSSVGVQTRAPRFGAYIASKAALDSLCDALQAETVHDNVRFTTVHMALV
HHHHHCCCEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHH
RTPMISPTTIYDKFPTLTPDQAAGVITDAIVHRPRRASSPFGQFAAVADAVNPAVMDRVR
HCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHH
NRAFNMFGDSSAAKGSESQTDTSELDKRSETFVRATRGIHW
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036