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The map label for this gene is 121637427

Identifier: 121637427

GI number: 121637427

Start: 1711643

End: 1711960

Strand: Direct

Name: 121637427

Synonym: BCG_1558

Alternate gene names: NA

Gene position: 1711643-1711960 (Clockwise)

Preceding gene: 121637426

Following gene: 121637428

Centisome position: 39.13

GC content: 63.21

Gene sequence:

>318_bases
GTGAACGCGCCGTTGCGTGGTCAGGTCTATCGATGCGACCTCGGATACGGGGCCAAACCGTGGCTCATCGTCTCCAACAA
CGCCCGCAACCGTCACACCGCCGACGTGGTGGCTGTGCGCCTGACAACAACGCGGAGAACCATACCGACCTGGGTCGCCA
TGGGCCCCAGCGATCCATTGACCGGATACGTCAACGCGGACAACATCGAGACCCTCGGCAAAGACGAGCTCGGTGACTAC
CTCGGTGAGGTCACGCCGGCGACGATGAACAAAATCAACACGGCGCTCGCGACCGCGCTGGGGCTACCGTGGCCATGA

Upstream 100 bases:

>100_bases
CGGCCGCGATCCATGACAATCCGGCGTACCCGTACGAGTCTGAGGCCGAACGGAGCGCCGCGCGGGCCCGGCGCAACGCC
AGGCAGCAGCGCTCGGCACA

Downstream 100 bases:

>100_bases
TGGCCGCATCCCACGACGACGACACCGTCGACGGGTTGGCGACGGCCGTGCGCGGCGGTGACCGTGCGGCGCTGCCACGG
GCCATCACACTGGTCGAGTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 105; Mature: 105

Protein sequence:

>105_residues
MNAPLRGQVYRCDLGYGAKPWLIVSNNARNRHTADVVAVRLTTTRRTIPTWVAMGPSDPLTGYVNADNIETLGKDELGDY
LGEVTPATMNKINTALATALGLPWP

Sequences:

>Translated_105_residues
MNAPLRGQVYRCDLGYGAKPWLIVSNNARNRHTADVVAVRLTTTRRTIPTWVAMGPSDPLTGYVNADNIETLGKDELGDY
LGEVTPATMNKINTALATALGLPWP
>Mature_105_residues
MNAPLRGQVYRCDLGYGAKPWLIVSNNARNRHTADVVAVRLTTTRRTIPTWVAMGPSDPLTGYVNADNIETLGKDELGDY
LGEVTPATMNKINTALATALGLPWP

Specific function: Unknown

COG id: COG2337

COG function: function code T; Growth inhibitor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PemK/MazF family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1495_MYCTU (P64859)

Other databases:

- EMBL:   BX842576
- EMBL:   AE000516
- PIR:   B70712
- RefSeq:   NP_216011.1
- RefSeq:   NP_335995.1
- ProteinModelPortal:   P64859
- SMR:   P64859
- EnsemblBacteria:   EBMYCT00000002720
- EnsemblBacteria:   EBMYCT00000069914
- GeneID:   886504
- GeneID:   924433
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1542
- KEGG:   mtu:Rv1495
- TIGR:   MT1542
- TubercuList:   Rv1495
- GeneTree:   EBGT00050000018675
- HOGENOM:   HBG565153
- ProtClustDB:   CLSK791199
- InterPro:   IPR003477
- InterPro:   IPR011067
- Gene3D:   G3DSA:2.30.30.110

Pfam domain/function: PF02452 PemK; SSF50118 Plasmid_toxin

EC number: NA

Molecular weight: Translated: 11410; Mature: 11410

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPLRGQVYRCDLGYGAKPWLIVSNNARNRHTADVVAVRLTTTRRTIPTWVAMGPSDPL
CCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCEEEEEEEEECCCCCCCEEEEECCCCCC
TGYVNADNIETLGKDELGDYLGEVTPATMNKINTALATALGLPWP
EEEEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNAPLRGQVYRCDLGYGAKPWLIVSNNARNRHTADVVAVRLTTTRRTIPTWVAMGPSDPL
CCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCEEEEEEEEECCCCCCCEEEEECCCCCC
TGYVNADNIETLGKDELGDYLGEVTPATMNKINTALATALGLPWP
EEEEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036