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The map label for this gene is yggV [C]

Identifier: 121637272

GI number: 121637272

Start: 1534087

End: 1534701

Strand: Direct

Name: yggV [C]

Synonym: BCG_1403

Alternate gene names: 121637272

Gene position: 1534087-1534701 (Clockwise)

Preceding gene: 121637271

Following gene: 121637275

Centisome position: 35.07

GC content: 68.62

Gene sequence:

>615_bases
GTGGCGCTTGTGACCAAGCTTCTGGTCGCCAGCCGCAACCGCAAAAAGCTGGCCGAACTGCGCCGGGTGTTGGACGGCGC
CGGACTATCGGGTTTGACGCTGTTGTCGCTGGGCGATGTGTCGCCGCTGCCTGAAACACCAGAAACCGGTGTGACATTCG
AGGACAACGCGCTGGCCAAGGCGCGCGACGCGTTCTCCGCGACCGGACTTGCCAGCGTTGCCGACGACTCCGGTTTGGAG
GTGGCCGCACTGGGCGGCATGCCTGGCGTGCTGTCGGCCCGGTGGTCCGGCAGGTATGGCGACGATGCCGCGAACACCGC
GCTGTTGCTGGCGCAGTTGTGCGATGTGCCCGATGAGCGGCGCGGAGCAGCGTTCGTGTCGGCCTGCGCGTTGGTCTCGG
GGTCCGGCGAAGTTGTCGTGCGCGGTGAATGGCCCGGCACGATCGCCCGTGAGCCGCGCGGTGACGGCGGGTTCGGCTAC
GACCCGGTCTTCGTCCCGTACGGTGACGACCGCACAGCGGCCCAGCTGAGCCCGGCGGAAAAGGACGCGGTATCCCATCG
CGGTCGCGCGTTGGCTCTGCTGCTGCCGGCGCTGCGCTCCCTGGCGACAGGCTAA

Upstream 100 bases:

>100_bases
CGCTGCCGTATCCGGGTGTGCTGCCGCAGGGACCGCCACCGCCGAAGGCGTTTGGCACCTGACCGCGCCGCGACGATGCA
GAGCGGAGCGATGAGGAGGA

Downstream 100 bases:

>100_bases
AGCCCGAAGCGGGCCTTGATCTCTTTGGTCTGGAAGTGCTCGACGACGATGCCGAGCAGCGGAATTGTGCCGGCGAGCAG
AACACCGGCTGTTTTGCCGA

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MALVTKLLVASRNRKKLAELRRVLDGAGLSGLTLLSLGDVSPLPETPETGVTFEDNALAKARDAFSATGLASVADDSGLE
VAALGGMPGVLSARWSGRYGDDAANTALLLAQLCDVPDERRGAAFVSACALVSGSGEVVVRGEWPGTIAREPRGDGGFGY
DPVFVPYGDDRTAAQLSPAEKDAVSHRGRALALLLPALRSLATG

Sequences:

>Translated_204_residues
MALVTKLLVASRNRKKLAELRRVLDGAGLSGLTLLSLGDVSPLPETPETGVTFEDNALAKARDAFSATGLASVADDSGLE
VAALGGMPGVLSARWSGRYGDDAANTALLLAQLCDVPDERRGAAFVSACALVSGSGEVVVRGEWPGTIAREPRGDGGFGY
DPVFVPYGDDRTAAQLSPAEKDAVSHRGRALALLLPALRSLATG
>Mature_203_residues
ALVTKLLVASRNRKKLAELRRVLDGAGLSGLTLLSLGDVSPLPETPETGVTFEDNALAKARDAFSATGLASVADDSGLEV
AALGGMPGVLSARWSGRYGDDAANTALLLAQLCDVPDERRGAAFVSACALVSGSGEVVVRGEWPGTIAREPRGDGGFGYD
PVFVPYGDDRTAAQLSPAEKDAVSHRGRALALLLPALRSLATG

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Escherichia coli, GI1789324, Length=202, Percent_Identity=45.5445544554455, Blast_Score=156, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_MYCBO (P64308)

Other databases:

- EMBL:   BX248338
- RefSeq:   NP_855030.1
- ProteinModelPortal:   P64308
- SMR:   P64308
- EnsemblBacteria:   EBMYCT00000016795
- GeneID:   1090665
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1376
- GeneTree:   EBGT00050000017421
- HOGENOM:   HBG697237
- OMA:   TGVTFAE
- ProtClustDB:   PRK00120
- BioCyc:   MBOV233413:MB1376-MONOMER
- BRENDA:   3.6.1.15
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 21016; Mature: 20885

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVTKLLVASRNRKKLAELRRVLDGAGLSGLTLLSLGDVSPLPETPETGVTFEDNALAK
CHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCEECCCCHHH
ARDAFSATGLASVADDSGLEVAALGGMPGVLSARWSGRYGDDAANTALLLAQLCDVPDER
HHHHHHHCCCHHHCCCCCCEEEEECCCCCCEECCCCCCCCCHHHHHHHHHHHHHCCCCCC
RGAAFVSACALVSGSGEVVVRGEWPGTIAREPRGDGGFGYDPVFVPYGDDRTAAQLSPAE
CCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHCCCHH
KDAVSHRGRALALLLPALRSLATG
HHHHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ALVTKLLVASRNRKKLAELRRVLDGAGLSGLTLLSLGDVSPLPETPETGVTFEDNALAK
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCEECCCCHHH
ARDAFSATGLASVADDSGLEVAALGGMPGVLSARWSGRYGDDAANTALLLAQLCDVPDER
HHHHHHHCCCHHHCCCCCCEEEEECCCCCCEECCCCCCCCCHHHHHHHHHHHHHCCCCCC
RGAAFVSACALVSGSGEVVVRGEWPGTIAREPRGDGGFGYDPVFVPYGDDRTAAQLSPAE
CCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHCCCHH
KDAVSHRGRALALLLPALRSLATG
HHHHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972