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The map label for this gene is rnz [C]

Identifier: 121637270

GI number: 121637270

Start: 1532431

End: 1533252

Strand: Direct

Name: rnz [C]

Synonym: BCG_1401

Alternate gene names: 121637270

Gene position: 1532431-1533252 (Clockwise)

Preceding gene: 121637269

Following gene: 121637271

Centisome position: 35.03

GC content: 63.99

Gene sequence:

>822_bases
ATGCGTCGATGTATTCCGCATCGTTGTATCGGGCATGGCACAGTAGTGTCCGTGCGAATAACCGTGCTCGGATGCTCCGG
TAGCGTCGTGGGGCCGGATTCGCCTGCGTCGGGGTATTTGCTCCGAGCGCCGCACACACCGCCGTTGGTTATCGACTTCG
GCGGGGGTGTGCTCGGCGCGCTGCAACGGCACGCGGATCCCGCGTCGGTGCATGTGCTGCTGTCGCATCTGCATGCGGAC
CATTGTCTGGACTTGCCGGGACTTTTTGTGTGGCGGCGTTACCACCCGTCGCGTCCCTCTGGCAAGGCATTGTTGTACGG
CCCCAGCGACACCTGGTCGCGATTGGGGGCGGCGTCGTCCCCGTACGGTGGGGAGATTGACGACTGTTCGGATATCTTCG
ATGTTCACCACTGGGCCGACAGTGAGCCAGTGACGTTGGGCGCCCTTACGATAGTGCCGCGGCTGGTTGCCCACCCGACT
GAGTCGTTTGGCCTGCGGATCACCGATCCGAGCGGTGCGTCACTGGCTTATAGCGGCGACACCGGCATTTGTGACCAGCT
CGTCGAGCTGGCTCGCGGCGTCGACGTTTTCCTCTGCGAGGCCTCCTGGACACACTCGCCCAAACATCCACCCGATCTAC
ACCTGTCGGGCACCGAAGCCGGTATGGTTGCCGCGCAAGCCGGCGTTCGTGAGCTGCTGCTGACGCATATCCCGCCGTGG
ACTTCGCGTGAGGACGTCATCAGCGAGGCCAAGGCCGAGTTCGACGGCCCGGTGCACGCGGTGGTATGCGACGAGACGTT
CGAAGTCCGGCGAGCCGGCTAG

Upstream 100 bases:

>100_bases
CCAAATTGGCCGCACGATTCCTGGGTCCGGTGCTCGGTGGTGTGCAACCCGTTCACCCATCGCGCATTCATTAGGCCATG
GAAGAGATTCTCGTCACCGA

Downstream 100 bases:

>100_bases
GTCTAGGGTTGGCGTCGTGTCCAAGCGAGAAGACGGCCGGCTCGACCACGAGCTTCGCCCGGTGATCATCACCCGCGGTT
TCACCGAAAACCCGGCGGGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MRRCIPHRCIGHGTVVSVRITVLGCSGSVVGPDSPASGYLLRAPHTPPLVIDFGGGVLGALQRHADPASVHVLLSHLHAD
HCLDLPGLFVWRRYHPSRPSGKALLYGPSDTWSRLGAASSPYGGEIDDCSDIFDVHHWADSEPVTLGALTIVPRLVAHPT
ESFGLRITDPSGASLAYSGDTGICDQLVELARGVDVFLCEASWTHSPKHPPDLHLSGTEAGMVAAQAGVRELLLTHIPPW
TSREDVISEAKAEFDGPVHAVVCDETFEVRRAG

Sequences:

>Translated_273_residues
MRRCIPHRCIGHGTVVSVRITVLGCSGSVVGPDSPASGYLLRAPHTPPLVIDFGGGVLGALQRHADPASVHVLLSHLHAD
HCLDLPGLFVWRRYHPSRPSGKALLYGPSDTWSRLGAASSPYGGEIDDCSDIFDVHHWADSEPVTLGALTIVPRLVAHPT
ESFGLRITDPSGASLAYSGDTGICDQLVELARGVDVFLCEASWTHSPKHPPDLHLSGTEAGMVAAQAGVRELLLTHIPPW
TSREDVISEAKAEFDGPVHAVVCDETFEVRRAG
>Mature_273_residues
MRRCIPHRCIGHGTVVSVRITVLGCSGSVVGPDSPASGYLLRAPHTPPLVIDFGGGVLGALQRHADPASVHVLLSHLHAD
HCLDLPGLFVWRRYHPSRPSGKALLYGPSDTWSRLGAASSPYGGEIDDCSDIFDVHHWADSEPVTLGALTIVPRLVAHPT
ESFGLRITDPSGASLAYSGDTGICDQLVELARGVDVFLCEASWTHSPKHPPDLHLSGTEAGMVAAQAGVRELLLTHIPPW
TSREDVISEAKAEFDGPVHAVVCDETFEVRRAG

Specific function: Zinc Phosphodiesterase, Which Displays Some Trna 3'- Processing Endonuclease Activity. Probably Involved In Trna Maturation, By Removing A 3'Trailer From Precursor Trna. [C]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the atsA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1339_MYCTU (P66873)

Other databases:

- EMBL:   BX842576
- EMBL:   AE000516
- PIR:   B70739
- RefSeq:   NP_215855.1
- RefSeq:   NP_335831.1
- ProteinModelPortal:   P66873
- SMR:   P66873
- EnsemblBacteria:   EBMYCT00000003522
- EnsemblBacteria:   EBMYCT00000069181
- GeneID:   886972
- GeneID:   924660
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1380
- KEGG:   mtu:Rv1339
- TIGR:   MT1380
- TubercuList:   Rv1339
- GeneTree:   EBGT00050000017431
- HOGENOM:   HBG728821
- OMA:   HHDHVAD
- ProtClustDB:   CLSK791108
- GO:   GO:0040007
- InterPro:   IPR001279
- SMART:   SM00849

Pfam domain/function: PF00753 Lactamase_B

EC number: 3.1.26.11 [C]

Molecular weight: Translated: 29154; Mature: 29154

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRCIPHRCIGHGTVVSVRITVLGCSGSVVGPDSPASGYLLRAPHTPPLVIDFGGGVLGA
CCCCCCCHHCCCCEEEEEEEEEEECCCCCCCCCCCCCCEEEECCCCCCEEEECCCHHHHH
LQRHADPASVHVLLSHLHADHCLDLPGLFVWRRYHPSRPSGKALLYGPSDTWSRLGAASS
HHHCCCHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCCCCEEEECCCHHHHHHCCCCC
PYGGEIDDCSDIFDVHHWADSEPVTLGALTIVPRLVAHPTESFGLRITDPSGASLAYSGD
CCCCCCCCHHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCCHHCCEEEECCCCCEEEECCC
TGICDQLVELARGVDVFLCEASWTHSPKHPPDLHLSGTEAGMVAAQAGVRELLLTHIPPW
CCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCC
TSREDVISEAKAEFDGPVHAVVCDETFEVRRAG
CCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MRRCIPHRCIGHGTVVSVRITVLGCSGSVVGPDSPASGYLLRAPHTPPLVIDFGGGVLGA
CCCCCCCHHCCCCEEEEEEEEEEECCCCCCCCCCCCCCEEEECCCCCCEEEECCCHHHHH
LQRHADPASVHVLLSHLHADHCLDLPGLFVWRRYHPSRPSGKALLYGPSDTWSRLGAASS
HHHCCCHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCCCCEEEECCCHHHHHHCCCCC
PYGGEIDDCSDIFDVHHWADSEPVTLGALTIVPRLVAHPTESFGLRITDPSGASLAYSGD
CCCCCCCCHHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCCHHCCEEEECCCCCEEEECCC
TGICDQLVELARGVDVFLCEASWTHSPKHPPDLHLSGTEAGMVAAQAGVRELLLTHIPPW
CCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCC
TSREDVISEAKAEFDGPVHAVVCDETFEVRRAG
CCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036