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The map label for this gene is PE12 [H]

Identifier: 121637104

GI number: 121637104

Start: 1333100

End: 1334026

Strand: Reverse

Name: PE12 [H]

Synonym: BCG_1235c

Alternate gene names: 121637104

Gene position: 1334026-1333100 (Counterclockwise)

Preceding gene: 121637106

Following gene: 121637101

Centisome position: 30.5

GC content: 65.05

Gene sequence:

>927_bases
ATGTCGTTTGTGTTCGCGGCGCCAGAGGCACTGGCGGCGGCCGCTGCGGACATGGCCGGTATCGGTTCGACTCTTAACGC
CGCCAATGTGGTTGCGGCGGTTCCCACCACCGGAGTCCTGGCCGCAGCCGCGGACGAGGTCTCGACTCAGGTCGCCGCGC
TGCTTTCCGCGCATGCTCAGGGGTATCAGCAGCTCAGCCGGCAGATGATGACAGCCTTCCACGACCAGTTCGTGCAGGCG
CTGAGAGCAAGTGCAGACGCGTATGCAACCGCCGAGGCCAGCGCCGCGCAGACCATGGTGAACGCCGTGAATGCGCCCGC
AAGAGCGTTGCTGGGGCATCCACTGATTAGCGCCGACGCCTCGACGGGTGGGGGCTCGAACGCGCTGAGCCGGGTCCACA
GCATGTTCCTCGGCACTGGCGGCTCCAGTGCACTTGGCGGTAGCGCCGCTGCAAATGCCGCTGCCAGCGGTGCACTGCAG
CTCCAACCCACCGGTGGGGCCAGCGGTTTGTCCGCCGTCGGCGCCCTGCTGCCGCGCGCCGGAGCGGCCGCCGCCGCGGC
GCTGCCGGCTCTGGCCGCCGAGTCGATCGGCAACGCAATCAAGAATCTCTACAACGCCGTCGAACCGTGGGTGCAGTACG
GCTTCAACCTCACCGCATGGGCGGTGGGATGGCTGCCCTACATCGGCATACTGGCACCGCAGATCAACTTCTTCTATTAC
CTCGGCGAGCCCATCGTGCAGGCAGTCCTGTTCAATGCGATCGACTTCGTGGACGGGACAGTCACTTTCAGCCAGGCACT
AACCAATATCGAAACGGCCACCGCGGCATCGATCAACCAATTCATCAACACCGAGATCAACTGGATACGCGGCTTCCTGC
CGCCGTTGCCGCCAATCAGCCCGCCGGGATTCCCGTCTTTGCCCTAA

Upstream 100 bases:

>100_bases
GCGCAGGTCACAGCCGATCGCGATACCATCCGTGAGAGGCCAGCGTCTGAACAAGCCCCCGGCGACAGCCGCCGCGTGGT
GAACCAGGAGAAGGTACGAG

Downstream 100 bases:

>100_bases
CTTCGGACTAGCCAGATCCGTCAGCTTGGACCCTGCGCCGCCACAGCACCCACGCCGGTGGCACGGCCCCTGCCACGACG
AACACCAGCGCGCCGTAGAC

Product: PE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSFVFAAPEALAAAAADMAGIGSTLNAANVVAAVPTTGVLAAAADEVSTQVAALLSAHAQGYQQLSRQMMTAFHDQFVQA
LRASADAYATAEASAAQTMVNAVNAPARALLGHPLISADASTGGGSNALSRVHSMFLGTGGSSALGGSAAANAAASGALQ
LQPTGGASGLSAVGALLPRAGAAAAAALPALAAESIGNAIKNLYNAVEPWVQYGFNLTAWAVGWLPYIGILAPQINFFYY
LGEPIVQAVLFNAIDFVDGTVTFSQALTNIETATAASINQFINTEINWIRGFLPPLPPISPPGFPSLP

Sequences:

>Translated_308_residues
MSFVFAAPEALAAAAADMAGIGSTLNAANVVAAVPTTGVLAAAADEVSTQVAALLSAHAQGYQQLSRQMMTAFHDQFVQA
LRASADAYATAEASAAQTMVNAVNAPARALLGHPLISADASTGGGSNALSRVHSMFLGTGGSSALGGSAAANAAASGALQ
LQPTGGASGLSAVGALLPRAGAAAAAALPALAAESIGNAIKNLYNAVEPWVQYGFNLTAWAVGWLPYIGILAPQINFFYY
LGEPIVQAVLFNAIDFVDGTVTFSQALTNIETATAASINQFINTEINWIRGFLPPLPPISPPGFPSLP
>Mature_307_residues
SFVFAAPEALAAAAADMAGIGSTLNAANVVAAVPTTGVLAAAADEVSTQVAALLSAHAQGYQQLSRQMMTAFHDQFVQAL
RASADAYATAEASAAQTMVNAVNAPARALLGHPLISADASTGGGSNALSRVHSMFLGTGGSSALGGSAAANAAASGALQL
QPTGGASGLSAVGALLPRAGAAAAAALPALAAESIGNAIKNLYNAVEPWVQYGFNLTAWAVGWLPYIGILAPQINFFYYL
GEPIVQAVLFNAIDFVDGTVTFSQALTNIETATAASINQFINTEINWIRGFLPPLPPISPPGFPSLP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PE family. PGRS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000084 [H]

Pfam domain/function: PF00934 PE [H]

EC number: NA

Molecular weight: Translated: 31011; Mature: 30880

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFVFAAPEALAAAAADMAGIGSTLNAANVVAAVPTTGVLAAAADEVSTQVAALLSAHAQ
CCEEECCHHHHHHHHHHHHHCCCHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
GYQQLSRQMMTAFHDQFVQALRASADAYATAEASAAQTMVNAVNAPARALLGHPLISADA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCC
STGGGSNALSRVHSMFLGTGGSSALGGSAAANAAASGALQLQPTGGASGLSAVGALLPRA
CCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCC
GAAAAAALPALAAESIGNAIKNLYNAVEPWVQYGFNLTAWAVGWLPYIGILAPQINFFYY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEE
LGEPIVQAVLFNAIDFVDGTVTFSQALTNIETATAASINQFINTEINWIRGFLPPLPPIS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PPGFPSLP
CCCCCCCC
>Mature Secondary Structure 
SFVFAAPEALAAAAADMAGIGSTLNAANVVAAVPTTGVLAAAADEVSTQVAALLSAHAQ
CEEECCHHHHHHHHHHHHHCCCHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
GYQQLSRQMMTAFHDQFVQALRASADAYATAEASAAQTMVNAVNAPARALLGHPLISADA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCC
STGGGSNALSRVHSMFLGTGGSSALGGSAAANAAASGALQLQPTGGASGLSAVGALLPRA
CCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCC
GAAAAAALPALAAESIGNAIKNLYNAVEPWVQYGFNLTAWAVGWLPYIGILAPQINFFYY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEE
LGEPIVQAVLFNAIDFVDGTVTFSQALTNIETATAASINQFINTEINWIRGFLPPLPPIS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PPGFPSLP
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]