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The map label for this gene is PPE16

Identifier: 121637067

GI number: 121637067

Start: 1293687

End: 1295543

Strand: Reverse

Name: PPE16

Synonym: BCG_1196c

Alternate gene names: 121637067

Gene position: 1295543-1293687 (Counterclockwise)

Preceding gene: 121637070

Following gene: 121637065

Centisome position: 29.62

GC content: 64.14

Gene sequence:

>1857_bases
ATGAGTTTTCTGGTGTTGCCTCCCGAGGTCAATTCCGCGTTGATGTTTGCCGGTGCGGGCTCAGGCCCGACGCTGGCCGC
CGCGGCGGCCTGGGACGGGCTGGCCGCCGAGTTAGGCCAAGCGGCGAACTCGTTTTCGTCGGCCACCGCAGCGCTGGCCG
ACACCGCCTGGCAAGGTCCGGCGGCGACGGCGATGGCCGCCGCGGCAGCCCCCTATGCCAGCTGGCTAAGCACGGCAGCA
ACACGCGCGCTAAGCGCGGCCGCACAGGCCAAGGCGGCCGCGGCGGTGTATGAAGCCGCGCGGGCGGCCACCGTGGATCC
ACTGCTGGTCGCCGCCAACCGCCACCAGCTGGTGTCGCTGGTGCTATCAAACCTGTTCGGCCAAAACGCCCCGGCGATCG
CGGCGACCGAGGCAGCCTACGAACAATTGTGGGCCGCCGATGTCGCGGCCATGGTGAGCTACCACAGCGGGGCCTCGGCG
GTGGCCGCCCAGCTGGCCCCGTGGGCACAGGCGGTGCGCGCCCTGCCCAACCCGACGGCGCCCGCACTGGCCTCCGGCCC
CGCTGCCCTGGCCATCCCGGCATTGGGTATCGGCAACACCGGCATCGGCAACATCTTCAGCATCGGCAACATCGGCGACT
ACAACCTAGGCAACGGCAATACCGGCAACGCAAACCTAGGCAGCGGAAACACGGGCCAGGCCAACCTGGGCAGCGGCAAT
ACCGGTTTCTTCAACTTTGGCAGCGGCAACACCGCCAACACCAACTTCGGTAGCGGGAACCTCGGCAACCTCAACCTGGG
CAGCGGCAACGACGGCAACGGTAACTTCGGCCTGGGGAATATCGGCGATGGCAACCGGGGCAGCGGGAACGTCGGCAGCT
TCAACTTCGGCACCGCCAACGCCGGTTCCTTCAACGTGGGCAGCGCAAATCACGGCTCTCCCAACGTGGGCTTTGCGAAT
CTCGGCAACAACAACCTGGGCATTGCGAATCTCGGCAACAACAACCTGGGCATTGCGAATCTCGGCAACAACAACATCGG
TATCGGGCTCACCGGCGACAACATGATCGGCATCGGCGCACTGAACTCCGGCATCGGCAACCTCGGCTTCGGCAACTCCG
GGAACAACAACATCGGCTTGTTCAACTCCGGCAACAACAACATCGGCTTCTTCAACTCCGGCGACAGCAACTTCGGCTTC
TTCAACTCCGGTGACACCAACACCGGTTTCGGGAACGCGGGCTTCACCAACACCGGCTTCGGGAACGCGGGCAGCGGCAA
CTTCGGTTTCGGGAACGCAGGCAACAACAACTTCGGGTTCGGCAACTCGGGATTTGAGAACATGGGTGTCGGCAACTCGG
GTGCCTACAACACGGGCAGCTTCAACTCGGGCACCTTGAATACCGGAGACTTGAACTCGGGCGACTTCAATACCGGCTGG
GCCAACTCGGGCGATATCAACACTGGCGGCTTCCACTCCGGAGACCTGAACACCGGGTTCGGCAGCCCGGTGGACCAACC
GGTGATGAACTCCGGCTTCGGCAACATCGGCACCGGCAACTCGGGCTTCAATAACTCCGGCGACGCGAACTCCGGCTTCC
AGAACACCAACACCGGCGCCTTCTTCATCGGTCACTCGGGTCTGCTCAATTCCGGCGGCGGCCAGCACGTGGGCATCAGC
AACTCGGGAACCGGCTTTAACACGGGCCTGTTCAACACCGGCTTCAACAACACCGGCATCGGAAACTCGGCCACCAACGC
CGCCTTCACCACCACCTCCGGGGTGGCCAACTCCGGCGACAACAGCTCAGGCGGGTTCAACGCCGGTAATGACCAGTCCG
GGTTCTTCGACGGTTAG

Upstream 100 bases:

>100_bases
TCGCGCCGGGAGGATCGGGCTGTGCGTATTCAGCCAGCGGAGGTTTGTGGTCACGGGAGGGGATGGCCCGGGCACGTCCA
GCTGCGGAAGGGATGGCGTG

Downstream 100 bases:

>100_bases
CCCCCGGATTCCAGCAGCCTGCGCCGCGCGAGATCCTTCGCGTTGGCCCGCCTGACCGCCACCGTCATGGCGGGTGCGGC
GATTCCCGCGAAGCGGGAAG

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 618; Mature: 617

Protein sequence:

>618_residues
MSFLVLPPEVNSALMFAGAGSGPTLAAAAAWDGLAAELGQAANSFSSATAALADTAWQGPAATAMAAAAAPYASWLSTAA
TRALSAAAQAKAAAAVYEAARAATVDPLLVAANRHQLVSLVLSNLFGQNAPAIAATEAAYEQLWAADVAAMVSYHSGASA
VAAQLAPWAQAVRALPNPTAPALASGPAALAIPALGIGNTGIGNIFSIGNIGDYNLGNGNTGNANLGSGNTGQANLGSGN
TGFFNFGSGNTANTNFGSGNLGNLNLGSGNDGNGNFGLGNIGDGNRGSGNVGSFNFGTANAGSFNVGSANHGSPNVGFAN
LGNNNLGIANLGNNNLGIANLGNNNIGIGLTGDNMIGIGALNSGIGNLGFGNSGNNNIGLFNSGNNNIGFFNSGDSNFGF
FNSGDTNTGFGNAGFTNTGFGNAGSGNFGFGNAGNNNFGFGNSGFENMGVGNSGAYNTGSFNSGTLNTGDLNSGDFNTGW
ANSGDINTGGFHSGDLNTGFGSPVDQPVMNSGFGNIGTGNSGFNNSGDANSGFQNTNTGAFFIGHSGLLNSGGGQHVGIS
NSGTGFNTGLFNTGFNNTGIGNSATNAAFTTTSGVANSGDNSSGGFNAGNDQSGFFDG

Sequences:

>Translated_618_residues
MSFLVLPPEVNSALMFAGAGSGPTLAAAAAWDGLAAELGQAANSFSSATAALADTAWQGPAATAMAAAAAPYASWLSTAA
TRALSAAAQAKAAAAVYEAARAATVDPLLVAANRHQLVSLVLSNLFGQNAPAIAATEAAYEQLWAADVAAMVSYHSGASA
VAAQLAPWAQAVRALPNPTAPALASGPAALAIPALGIGNTGIGNIFSIGNIGDYNLGNGNTGNANLGSGNTGQANLGSGN
TGFFNFGSGNTANTNFGSGNLGNLNLGSGNDGNGNFGLGNIGDGNRGSGNVGSFNFGTANAGSFNVGSANHGSPNVGFAN
LGNNNLGIANLGNNNLGIANLGNNNIGIGLTGDNMIGIGALNSGIGNLGFGNSGNNNIGLFNSGNNNIGFFNSGDSNFGF
FNSGDTNTGFGNAGFTNTGFGNAGSGNFGFGNAGNNNFGFGNSGFENMGVGNSGAYNTGSFNSGTLNTGDLNSGDFNTGW
ANSGDINTGGFHSGDLNTGFGSPVDQPVMNSGFGNIGTGNSGFNNSGDANSGFQNTNTGAFFIGHSGLLNSGGGQHVGIS
NSGTGFNTGLFNTGFNNTGIGNSATNAAFTTTSGVANSGDNSSGGFNAGNDQSGFFDG
>Mature_617_residues
SFLVLPPEVNSALMFAGAGSGPTLAAAAAWDGLAAELGQAANSFSSATAALADTAWQGPAATAMAAAAAPYASWLSTAAT
RALSAAAQAKAAAAVYEAARAATVDPLLVAANRHQLVSLVLSNLFGQNAPAIAATEAAYEQLWAADVAAMVSYHSGASAV
AAQLAPWAQAVRALPNPTAPALASGPAALAIPALGIGNTGIGNIFSIGNIGDYNLGNGNTGNANLGSGNTGQANLGSGNT
GFFNFGSGNTANTNFGSGNLGNLNLGSGNDGNGNFGLGNIGDGNRGSGNVGSFNFGTANAGSFNVGSANHGSPNVGFANL
GNNNLGIANLGNNNLGIANLGNNNIGIGLTGDNMIGIGALNSGIGNLGFGNSGNNNIGLFNSGNNNIGFFNSGDSNFGFF
NSGDTNTGFGNAGFTNTGFGNAGSGNFGFGNAGNNNFGFGNSGFENMGVGNSGAYNTGSFNSGTLNTGDLNSGDFNTGWA
NSGDINTGGFHSGDLNTGFGSPVDQPVMNSGFGNIGTGNSGFNNSGDANSGFQNTNTGAFFIGHSGLLNSGGGQHVGISN
SGTGFNTGLFNTGFNNTGIGNSATNAAFTTTSGVANSGDNSSGGFNAGNDQSGFFDG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

Organism=Caenorhabditis elegans, GI17556172, Length=180, Percent_Identity=22.7777777777778, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21357785, Length=106, Percent_Identity=41.5094339622642, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE16_MYCTU (Q79FS0)

Other databases:

- EMBL:   BX842575
- EMBL:   AE000516
- PIR:   H70552
- RefSeq:   NP_335611.1
- RefSeq:   YP_177790.1
- HSSP:   Q79FE1
- ProteinModelPortal:   Q79FS0
- SMR:   Q79FS0
- EnsemblBacteria:   EBMYCT00000003523
- EnsemblBacteria:   EBMYCT00000072783
- GeneID:   885131
- GeneID:   924923
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1168
- KEGG:   mtu:Rv1135c
- TIGR:   MT1168
- TubercuList:   Rv1135c
- GeneTree:   EBGT00050000014886
- HOGENOM:   HBG572308
- OMA:   NKSSYGD
- ProtClustDB:   CLSK799780
- InterPro:   IPR002989
- InterPro:   IPR000030

Pfam domain/function: PF01469 Pentapeptide_2; PF00823 PPE

EC number: NA

Molecular weight: Translated: 60207; Mature: 60076

Theoretical pI: Translated: 3.93; Mature: 3.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLVLPPEVNSALMFAGAGSGPTLAAAAAWDGLAAELGQAANSFSSATAALADTAWQGP
CCEEEECCCCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AATAMAAAAAPYASWLSTAATRALSAAAQAKAAAAVYEAARAATVDPLLVAANRHQLVSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHH
VLSNLFGQNAPAIAATEAAYEQLWAADVAAMVSYHSGASAVAAQLAPWAQAVRALPNPTA
HHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
PALASGPAALAIPALGIGNTGIGNIFSIGNIGDYNLGNGNTGNANLGSGNTGQANLGSGN
CCCCCCCCEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TGFFNFGSGNTANTNFGSGNLGNLNLGSGNDGNGNFGLGNIGDGNRGSGNVGSFNFGTAN
CCEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCC
AGSFNVGSANHGSPNVGFANLGNNNLGIANLGNNNLGIANLGNNNIGIGLTGDNMIGIGA
CCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCEEEEECCCCCEEEEECCCCEEEEEC
LNSGIGNLGFGNSGNNNIGLFNSGNNNIGFFNSGDSNFGFFNSGDTNTGFGNAGFTNTGF
CCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
GNAGSGNFGFGNAGNNNFGFGNSGFENMGVGNSGAYNTGSFNSGTLNTGDLNSGDFNTGW
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ANSGDINTGGFHSGDLNTGFGSPVDQPVMNSGFGNIGTGNSGFNNSGDANSGFQNTNTGA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
FFIGHSGLLNSGGGQHVGISNSGTGFNTGLFNTGFNNTGIGNSATNAAFTTTSGVANSGD
EEEECCCCCCCCCCCEEECCCCCCCCCCCCEECCCCCCCCCCCCCCCEEEECCCCCCCCC
NSSGGFNAGNDQSGFFDG
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SFLVLPPEVNSALMFAGAGSGPTLAAAAAWDGLAAELGQAANSFSSATAALADTAWQGP
CEEEECCCCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AATAMAAAAAPYASWLSTAATRALSAAAQAKAAAAVYEAARAATVDPLLVAANRHQLVSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHH
VLSNLFGQNAPAIAATEAAYEQLWAADVAAMVSYHSGASAVAAQLAPWAQAVRALPNPTA
HHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
PALASGPAALAIPALGIGNTGIGNIFSIGNIGDYNLGNGNTGNANLGSGNTGQANLGSGN
CCCCCCCCEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TGFFNFGSGNTANTNFGSGNLGNLNLGSGNDGNGNFGLGNIGDGNRGSGNVGSFNFGTAN
CCEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCC
AGSFNVGSANHGSPNVGFANLGNNNLGIANLGNNNLGIANLGNNNIGIGLTGDNMIGIGA
CCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCEEEEECCCCCEEEEECCCCEEEEEC
LNSGIGNLGFGNSGNNNIGLFNSGNNNIGFFNSGDSNFGFFNSGDTNTGFGNAGFTNTGF
CCCCCCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
GNAGSGNFGFGNAGNNNFGFGNSGFENMGVGNSGAYNTGSFNSGTLNTGDLNSGDFNTGW
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ANSGDINTGGFHSGDLNTGFGSPVDQPVMNSGFGNIGTGNSGFNNSGDANSGFQNTNTGA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
FFIGHSGLLNSGGGQHVGISNSGTGFNTGLFNTGFNNTGIGNSATNAAFTTTSGVANSGD
EEEECCCCCCCCCCCEEECCCCCCCCCCCCEECCCCCCCCCCCCCCCEEEECCCCCCCCC
NSSGGFNAGNDQSGFFDG
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036