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The map label for this gene is pbp [H]

Identifier: 121636830

GI number: 121636830

Start: 1040629

End: 1042209

Strand: Direct

Name: pbp [H]

Synonym: BCG_0959

Alternate gene names: 121636830

Gene position: 1040629-1042209 (Clockwise)

Preceding gene: 121636829

Following gene: 121636831

Centisome position: 23.79

GC content: 63.44

Gene sequence:

>1581_bases
ATGACCAAACGAGCGGCAACGGCCGCCATGGTGATGTTGCTGACGTTAACGGGTTGCGGATCCACGCACCAGGCACTTGG
CCCGCCGTCCGGGTTGCCCGATGCCTCTCCCAATGAGAGGTCAGCGATACAGATCCCCGCTGGCCGCATCGACGATGCCG
TGGCAAAGGTCGACGGCCTGGTCGGCGAGCTGATGCAGAATACCGGCATACCCGGAATGGCAGTGGCGATAGTCCATGGC
GGAAAGACGTTGTATGCCAAAGGGTTCGGTGTCAGAGACGTGGGCAAAGGTGGTGGTCCGGACAACAAGGTGGACGCCGA
CACCGTCTTTCAGTTGGCGTCGGTGTCCAAATCGGTCGGCGCCACGGTGGTGGCGCATGCGGTAACCGACAACGTCGTGA
CCTGGGATACGCCCGTCGTATCGAAGCTGCCGTGGTTTGCCCTTCGCGATCCCTACGTCACCGGCCAGGTAACCATTGCT
GACCTCTACTCGCATCGCTCCGGCCTGCCCGACCATGCGGGCGATCTGTTGGAGGATTTGGGTTATGACCGTCGACAGGT
ACTGCAGCGGCTGAAATACCTGCCGCTGGCACCGTTTCGAATCAGCTATGCCTACACCAACTTTGGTGTGACCGCGGCGG
CCGAAGCGGTCGCGGCCGCGGCCGGCCAGTCCTGGGAGGACCTGTCCGACGAGGTGCTCTACCGCCCGTTGGGGATGGGG
TCTACGAGTTCCCGGTTCACCGACTTTCTGGCCAGGCCCAACCATGCGGTCAACCACGTCAAGGTCGCAGACCGATGGGA
GGCGCGCTACCAGCGCGATCCCGACGCCCAATCACCTGCGGGCGGGGTGAGTTCGTCTCTTAACGACATGACGCACTGGC
TGGCCATGGTGCTGGCCGACGGCGTGTACAACGGCCGTCGGATCACGTCGCCGGAGGCCCTGCTCCTCGTCTACACGCCG
CAGGTGATCTCTCGACACCCGGTGTCACCGAGAGCGCGGGCCAGCTTCTATGGCTACGGATTCAACGTGGGGGTAACCTC
TTCGGGACGCACCGAGTACAGCCATTCCGGCGCCTTCGGGCTGGGTGCCGCGGCGAATTTCGTGGTGCTGCCCTCCGAAG
ACCTGGCCATCATCGCGCTGACCAACGCCGGGCCCATCGGCGTGCCGGAGACGCTGACCGCCGAATTCATGGACTTGGTG
CAGTACGGCCAGGTACGCGAGGACTGGGCGGCCCTGTACAAGAAGGCATTTGCCCCGCTGAACGAGCTCGCGGGCTCGCT
GGTCGGCAAGCAATCCCCGGCCAACCCAGCGCCGAGCAGACCGCTGAACGACTACGTCGGCGTGTACGCCAACGACTACT
GGGGGCCCGCCACCGTGACCTACCACGACGGCCAACTGCGCCTGTCGCTGGGGCCGAAGAACCAGACGTTCGATTTGACG
CACTGGGACGGCGACACTTTCACGTTCACGTTGTCGACCGAAAACGCATTGCCCGGATCGATTTCCAAGGCCACCTTCGC
CGGCGACACGTTAAACCTGGAATACTACGACGCCGACAAGCTGGGAACGTTTACCCGATGA

Upstream 100 bases:

>100_bases
GGCTGTAATTCCCCGCAGCGCCCGGCTAATGGTGCTAGGGGGCGAGCCGAGGCGATCAAACCACCGAGTGTTCCGGCCGC
GTTGGCTACTATCTGCGGCC

Downstream 100 bases:

>100_bases
CCCGTTCGGCTTCGGCGACAGCCGGTTTGACCGATGCCGAAGTGGCGCAACGGGTCGCCGAAGGCAAGAGCAACGATATC
CCGGAACGGGTCACCCGCAC

Product: hypothetical protein

Products: NA

Alternate protein names: PBP-4 [H]

Number of amino acids: Translated: 526; Mature: 525

Protein sequence:

>526_residues
MTKRAATAAMVMLLTLTGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAVAIVHG
GKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDPYVTGQVTIA
DLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMG
STSSRFTDFLARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALLLVYTP
QVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLV
QYGQVREDWAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLT
HWDGDTFTFTLSTENALPGSISKATFAGDTLNLEYYDADKLGTFTR

Sequences:

>Translated_526_residues
MTKRAATAAMVMLLTLTGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAVAIVHG
GKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDPYVTGQVTIA
DLYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMG
STSSRFTDFLARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALLLVYTP
QVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLV
QYGQVREDWAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLT
HWDGDTFTFTLSTENALPGSISKATFAGDTLNLEYYDADKLGTFTR
>Mature_525_residues
TKRAATAAMVMLLTLTGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGLVGELMQNTGIPGMAVAIVHGG
KTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVGATVVAHAVTDNVVTWDTPVVSKLPWFALRDPYVTGQVTIAD
LYSHRSGLPDHAGDLLEDLGYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMGS
TSSRFTDFLARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLADGVYNGRRITSPEALLLVYTPQ
VISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFGLGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLVQ
YGQVREDWAALYKKAFAPLNELAGSLVGKQSPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLTH
WDGDTFTFTLSTENALPGSISKATFAGDTLNLEYYDADKLGTFTR

Specific function: Involved in cell wall biosynthesis and may also act as a sensor of external penicillins [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI1786574, Length=354, Percent_Identity=22.5988700564972, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115533026, Length=360, Percent_Identity=22.2222222222222, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 56221; Mature: 56089

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRAATAAMVMLLTLTGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGL
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHH
VGELMQNTGIPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVG
HHHHHHHCCCCCEEEEEEECCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
ATVVAHAVTDNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDL
HHEEEHHHCCCEEECCCCHHHHCCCEEECCCCCCCEEEHEEHHHHCCCCCHHHHHHHHHC
GYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMG
CCCHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
STSSRFTDFLARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLAD
CCHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
GVYNGRRITSPEALLLVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFG
CCCCCCEECCCCEEEEEECCHHHHCCCCCCCCCCEEEECCEEEEECCCCCCCCCCCCCCC
LGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPL
CCCCCCEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCH
NELAGSLVGKQSPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLT
HHHHHHHHCCCCCCCCCCCCCCCHHHEEEECCCCCCEEEEEECCEEEEEECCCCCEEEEE
HWDGDTFTFTLSTENALPGSISKATFAGDTLNLEYYDADKLGTFTR
EECCCEEEEEEECCCCCCCCCCCCEECCCEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
TKRAATAAMVMLLTLTGCGSTHQALGPPSGLPDASPNERSAIQIPAGRIDDAVAKVDGL
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHH
VGELMQNTGIPGMAVAIVHGGKTLYAKGFGVRDVGKGGGPDNKVDADTVFQLASVSKSVG
HHHHHHHCCCCCEEEEEEECCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
ATVVAHAVTDNVVTWDTPVVSKLPWFALRDPYVTGQVTIADLYSHRSGLPDHAGDLLEDL
HHEEEHHHCCCEEECCCCHHHHCCCEEECCCCCCCEEEHEEHHHHCCCCCHHHHHHHHHC
GYDRRQVLQRLKYLPLAPFRISYAYTNFGVTAAAEAVAAAAGQSWEDLSDEVLYRPLGMG
CCCHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
STSSRFTDFLARPNHAVNHVKVADRWEARYQRDPDAQSPAGGVSSSLNDMTHWLAMVLAD
CCHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
GVYNGRRITSPEALLLVYTPQVISRHPVSPRARASFYGYGFNVGVTSSGRTEYSHSGAFG
CCCCCCEECCCCEEEEEECCHHHHCCCCCCCCCCEEEECCEEEEECCCCCCCCCCCCCCC
LGAAANFVVLPSEDLAIIALTNAGPIGVPETLTAEFMDLVQYGQVREDWAALYKKAFAPL
CCCCCCEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCH
NELAGSLVGKQSPANPAPSRPLNDYVGVYANDYWGPATVTYHDGQLRLSLGPKNQTFDLT
HHHHHHHHCCCCCCCCCCCCCCCHHHEEEECCCCCCEEEEEECCEEEEEECCCCCEEEEE
HWDGDTFTFTLSTENALPGSISKATFAGDTLNLEYYDADKLGTFTR
EECCCEEEEEEECCCCCCCCCCCCEECCCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8440253 [H]