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The map label for this gene is 121636815

Identifier: 121636815

GI number: 121636815

Start: 1024310

End: 1025797

Strand: Direct

Name: 121636815

Synonym: BCG_0944

Alternate gene names: NA

Gene position: 1024310-1025797 (Clockwise)

Preceding gene: 121636811

Following gene: 121636817

Centisome position: 23.42

GC content: 58.74

Gene sequence:

>1488_bases
ATGACCGGGCGATGTCCGACGGTTGCCGTGGTCGGAGCGGGTATGTCCGGAATGTGCGTCGCAATTACGTTGCTGAGCGC
AGGGATTACTGATGTCTGCATCTATGAAAAGGCCGACGATGTTGGCGGAACGTGGCGCGATAACACCTATCCAGGTCTGA
CATGTGATGTGCCGTCCCGGCTCTATCAGTACAGCTTTGCCAAGAATCCGAACTGGACCCAGATGTTTTCACGCGGAGGC
GAAATCCAAGATTACTTGCGTGGGATCGCCGAGCGCTACGGGCTGAGGCACCGGATTCGGTTTGGCGCCACGGTTGTCAG
CGCCCGATTCGACGACGGCCGGTGGGTGTTGCGCACCGATTCCGGAACGGAGTCGACAGTAGACTTCTTGATTTCGGCCA
CCGGCGTTTTACATCATCCCCGAATACCGCCGATCGCTGGTTTGGACGACTTCAGGGGGACGGTGTTTCACTCGGCTCGC
TGGGATCACACGGTTCCGCTGCTGGGACGCCGAATCGCGGTGATCGGTACCGGGTCCACGGGCGTACAACTCGTCTGCGG
CCTGGCTGGGGTCGCGGGTAAAGTCACCATGTTCCAGCGCACCGCACAATGGGTGCTGCCGTGGCCTAACCCTCGATACT
CGAAGCTGGCGCGTGTTTTCCACCGCGCTTTTCCGTGTCTGGGTTCGCTGGCCTATAAGGCATATAGCCTTTCCTTCGAA
ACGTTCGCGGTTGCGCTCAGCAATCCAGGTTTGCACCGAAAGCTGGTAGGGGCCGTGTGTCGCGCCAGCTTACGTCGGGT
GCGTGACCCCCGACTGCGTCGGGCACTGACGCCTGATTACGAGCCGATGTGCAAACGGCTAGTGATGTCCGGCGGATTCT
ATCGGGCGATTCAGCGTGACGACGTCGAATTAGTCACCGCCGGTATCGATCACGTCGAACATCGGGGCATCGTCACCGAT
GATGGTGTGTTGCACGAGGTGGACGTCATCGTGCTTGCCACGGGGTTTGACTCTCATGCATTTTTCCGGCCGATGCAGCT
GACCGGTCGCGACGGCATCAGGATCGACGATGTGTGGCAAGACGGTCCGCATGCTCATCAAACCGTCGCAATACCTGGAT
TTCCGAACTTCTTTATGATGTTGGGGCCACACAGCCCAGTGGGAAACTTCCCGCTGACAGCGGTCGCCGAATCTCAGGCT
GAACACATAGTGCAGTGGATAAAGCGATGGCGCCATGGTGAATTCGACACCATGGAACCGAAGTCAGCTGCTACCGAAGC
ATATAACACGGTGTTGCGGGCCGCGATGCCGAACACCGTCTGGACCACCGGCTGCGACAGCTGGTACCTGAACAAAGACG
GTATTCCTGAGGTTTGGCCATTTGCACCGGCCAAACACCGCGCCATGCTCGCTAACCTACATCCCGAAGAATACGACCTG
CGACGCTATGCTGCGGTGCGCGCAACTAGTCGGCCTCAAAGCGCTTGA

Upstream 100 bases:

>100_bases
AACAGCGTCGCGTGTTTGTCTCGGTAGCTGCTCTGTATAGTATGCGTTGCTTAACCGCATGTGGGAGGGTGATTTTGGGC
TGTTCTGGGGGGTCGGAGCG

Downstream 100 bases:

>100_bases
AGCCTATCGAGGTGCTGGACGGTGACGTTCGCGCGGGATCGGCCACTAATCCCGTTCTGACGGCGCTGACAAAGGTTATA
GCGGTGACCATTGGCGCAGC

Product: putative monooxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MTGRCPTVAVVGAGMSGMCVAITLLSAGITDVCIYEKADDVGGTWRDNTYPGLTCDVPSRLYQYSFAKNPNWTQMFSRGG
EIQDYLRGIAERYGLRHRIRFGATVVSARFDDGRWVLRTDSGTESTVDFLISATGVLHHPRIPPIAGLDDFRGTVFHSAR
WDHTVPLLGRRIAVIGTGSTGVQLVCGLAGVAGKVTMFQRTAQWVLPWPNPRYSKLARVFHRAFPCLGSLAYKAYSLSFE
TFAVALSNPGLHRKLVGAVCRASLRRVRDPRLRRALTPDYEPMCKRLVMSGGFYRAIQRDDVELVTAGIDHVEHRGIVTD
DGVLHEVDVIVLATGFDSHAFFRPMQLTGRDGIRIDDVWQDGPHAHQTVAIPGFPNFFMMLGPHSPVGNFPLTAVAESQA
EHIVQWIKRWRHGEFDTMEPKSAATEAYNTVLRAAMPNTVWTTGCDSWYLNKDGIPEVWPFAPAKHRAMLANLHPEEYDL
RRYAAVRATSRPQSA

Sequences:

>Translated_495_residues
MTGRCPTVAVVGAGMSGMCVAITLLSAGITDVCIYEKADDVGGTWRDNTYPGLTCDVPSRLYQYSFAKNPNWTQMFSRGG
EIQDYLRGIAERYGLRHRIRFGATVVSARFDDGRWVLRTDSGTESTVDFLISATGVLHHPRIPPIAGLDDFRGTVFHSAR
WDHTVPLLGRRIAVIGTGSTGVQLVCGLAGVAGKVTMFQRTAQWVLPWPNPRYSKLARVFHRAFPCLGSLAYKAYSLSFE
TFAVALSNPGLHRKLVGAVCRASLRRVRDPRLRRALTPDYEPMCKRLVMSGGFYRAIQRDDVELVTAGIDHVEHRGIVTD
DGVLHEVDVIVLATGFDSHAFFRPMQLTGRDGIRIDDVWQDGPHAHQTVAIPGFPNFFMMLGPHSPVGNFPLTAVAESQA
EHIVQWIKRWRHGEFDTMEPKSAATEAYNTVLRAAMPNTVWTTGCDSWYLNKDGIPEVWPFAPAKHRAMLANLHPEEYDL
RRYAAVRATSRPQSA
>Mature_494_residues
TGRCPTVAVVGAGMSGMCVAITLLSAGITDVCIYEKADDVGGTWRDNTYPGLTCDVPSRLYQYSFAKNPNWTQMFSRGGE
IQDYLRGIAERYGLRHRIRFGATVVSARFDDGRWVLRTDSGTESTVDFLISATGVLHHPRIPPIAGLDDFRGTVFHSARW
DHTVPLLGRRIAVIGTGSTGVQLVCGLAGVAGKVTMFQRTAQWVLPWPNPRYSKLARVFHRAFPCLGSLAYKAYSLSFET
FAVALSNPGLHRKLVGAVCRASLRRVRDPRLRRALTPDYEPMCKRLVMSGGFYRAIQRDDVELVTAGIDHVEHRGIVTDD
GVLHEVDVIVLATGFDSHAFFRPMQLTGRDGIRIDDVWQDGPHAHQTVAIPGFPNFFMMLGPHSPVGNFPLTAVAESQAE
HIVQWIKRWRHGEFDTMEPKSAATEAYNTVLRAAMPNTVWTTGCDSWYLNKDGIPEVWPFAPAKHRAMLANLHPEEYDLR
RYAAVRATSRPQSA

Specific function: Unknown

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family

Homologues:

Organism=Homo sapiens, GI4503757, Length=348, Percent_Identity=23.8505747126437, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI4503759, Length=361, Percent_Identity=24.3767313019391, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI4503755, Length=349, Percent_Identity=23.2091690544413, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI50541965, Length=348, Percent_Identity=23.5632183908046, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI50541961, Length=348, Percent_Identity=23.5632183908046, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI221316674, Length=350, Percent_Identity=21.7142857142857, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI221316672, Length=350, Percent_Identity=21.7142857142857, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI221316678, Length=218, Percent_Identity=25.6880733944954, Blast_Score=76, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI25145785, Length=260, Percent_Identity=25.3846153846154, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17555726, Length=354, Percent_Identity=27.4011299435028, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17561948, Length=352, Percent_Identity=26.4204545454545, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17541300, Length=330, Percent_Identity=24.5454545454545, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19921694, Length=210, Percent_Identity=26.6666666666667, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19922866, Length=210, Percent_Identity=27.1428571428571, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y892_MYCTU (P64745)

Other databases:

- EMBL:   BX842574
- EMBL:   AE000516
- PIR:   A70782
- RefSeq:   NP_215407.1
- RefSeq:   NP_335348.1
- ProteinModelPortal:   P64745
- SMR:   P64745
- EnsemblBacteria:   EBMYCT00000003015
- EnsemblBacteria:   EBMYCT00000070624
- GeneID:   885225
- GeneID:   926230
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0916
- KEGG:   mtu:Rv0892
- TIGR:   MT0916
- TubercuList:   Rv0892
- GeneTree:   EBGT00050000014936
- HOGENOM:   HBG655952
- OMA:   VEIDELW
- ProtClustDB:   CLSK790813
- InterPro:   IPR020946

Pfam domain/function: PF00743 FMO-like

EC number: NA

Molecular weight: Translated: 55040; Mature: 54908

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: BINDING 16-16 BINDING 36-36 BINDING 45-45 BINDING 56-56 BINDING 62-62 BINDING 105-105

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGRCPTVAVVGAGMSGMCVAITLLSAGITDVCIYEKADDVGGTWRDNTYPGLTCDVPSR
CCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCEEECCHHH
LYQYSFAKNPNWTQMFSRGGEIQDYLRGIAERYGLRHRIRFGATVVSARFDDGRWVLRTD
HHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCHHEEEECEEEEEEEECCCEEEEEEC
SGTESTVDFLISATGVLHHPRIPPIAGLDDFRGTVFHSARWDHTVPLLGRRIAVIGTGST
CCCHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCEEECCCCCCCHHHCCCEEEEEECCCC
GVQLVCGLAGVAGKVTMFQRTAQWVLPWPNPRYSKLARVFHRAFPCLGSLAYKAYSLSFE
HHHHHHHHHCCCHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECHH
TFAVALSNPGLHRKLVGAVCRASLRRVRDPRLRRALTPDYEPMCKRLVMSGGFYRAIQRD
HEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHCCCCEEECCCC
DVELVTAGIDHVEHRGIVTDDGVLHEVDVIVLATGFDSHAFFRPMQLTGRDGIRIDDVWQ
CCEEEEHHHHHHHHCCEECCCCCEEEEEEEEEEECCCCCHHCCCEEECCCCCCEECCCCC
DGPHAHQTVAIPGFPNFFMMLGPHSPVGNFPLTAVAESQAEHIVQWIKRWRHGEFDTMEP
CCCCCCEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
KSAATEAYNTVLRAAMPNTVWTTGCDSWYLNKDGIPEVWPFAPAKHRAMLANLHPEEYDL
HHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCCCCCCCCCCCCHHHHHHHCCCCCHHHH
RRYAAVRATSRPQSA
HHHHHHHCCCCCCCC
>Mature Secondary Structure 
TGRCPTVAVVGAGMSGMCVAITLLSAGITDVCIYEKADDVGGTWRDNTYPGLTCDVPSR
CCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCEEECCHHH
LYQYSFAKNPNWTQMFSRGGEIQDYLRGIAERYGLRHRIRFGATVVSARFDDGRWVLRTD
HHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCHHEEEECEEEEEEEECCCEEEEEEC
SGTESTVDFLISATGVLHHPRIPPIAGLDDFRGTVFHSARWDHTVPLLGRRIAVIGTGST
CCCHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCEEECCCCCCCHHHCCCEEEEEECCCC
GVQLVCGLAGVAGKVTMFQRTAQWVLPWPNPRYSKLARVFHRAFPCLGSLAYKAYSLSFE
HHHHHHHHHCCCHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECHH
TFAVALSNPGLHRKLVGAVCRASLRRVRDPRLRRALTPDYEPMCKRLVMSGGFYRAIQRD
HEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHCCCCEEECCCC
DVELVTAGIDHVEHRGIVTDDGVLHEVDVIVLATGFDSHAFFRPMQLTGRDGIRIDDVWQ
CCEEEEHHHHHHHHCCEECCCCCEEEEEEEEEEECCCCCHHCCCEEECCCCCCEECCCCC
DGPHAHQTVAIPGFPNFFMMLGPHSPVGNFPLTAVAESQAEHIVQWIKRWRHGEFDTMEP
CCCCCCEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
KSAATEAYNTVLRAAMPNTVWTTGCDSWYLNKDGIPEVWPFAPAKHRAMLANLHPEEYDL
HHHHHHHHHHHHHHHCCCCEEECCCCCEEECCCCCCCCCCCCCCHHHHHHHCCCCCHHHH
RRYAAVRATSRPQSA
HHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036