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The map label for this gene is fprB

Identifier: 121636809

GI number: 121636809

Start: 1014260

End: 1015987

Strand: Direct

Name: fprB

Synonym: BCG_0938

Alternate gene names: 121636809

Gene position: 1014260-1015987 (Clockwise)

Preceding gene: 121636808

Following gene: 121636811

Centisome position: 23.19

GC content: 67.77

Gene sequence:

>1728_bases
ATGCCGCACGTAATTACTCAGTCGTGCTGCAACGACGCGTCCTGCGTCTTCGCATGTCCGGTGAACTGCATCCACCCGAC
GCCGGACGAGCCGGGCTTCGCGACCTCGGAAATGCTCTATATCGATCCGGTGGCCTGCGTGGACTGTGGTGCCTGCGTAA
CCGCCTGCCCGGTCAGCGCGATCGCGCCGAACACCCGGTTGGACTTCGAGCAGCTGCCGTTCGTCGAAATCAATGCGTCG
TATTACCCGAAGCGGCCCGCCGGCGTGAAGCTAGCGCCGACGTCGAAGCTGGCTCCGGTGACTCCGGCCGCCGAGGTGCG
TGTGCGCCGGCAGCCGCTGACGGTAGCCGTCGTCGGGTCCGGGCCCGCGGCGATGTATGCCGCCGATGAGCTGCTGGTCC
AGCAGGGAGTGCAGGTCAACGTCTTTGAGAAGCTGCCGACACCCTACGGGCTGGTGCGCTCCGGGGTGGCGCCGGATCAC
CAGAACACCAAGCGGGTCACGCGACTATTTGACCGGATCGCCGGTCATCGCCGCTTCCGGTTCTATCTCAACGTCGAGAT
CGGCAAGCATCTAGGCCATGCCGAGCTATTGGCCCACCATCACGCCGTGCTGTACGCGGTCGGAGCGCCCGACGACCGCC
GGCTGACGATTGACGGGATGGGACTGCCGGGCACCGGTACCGCCACGGAGCTGGTCGCGTGGCTCAACGGACATCCCGAC
TTCAACGATCTGCCAGTCGATCTCAGTCACGAACGCGTGGTGATCATCGGCAACGGGAATGTCGCGCTCGACGTGGCGCG
CGTGCTTGCGGCCGATCCGCACGAGCTGGCCGCCACCGACATCGCCGACCACGCGTTGTCCGCGTTACGCAACTCGGCGG
TCCGTGAGGTGGTGGTCGCCGCCCGCCGCGGTCCTGCCCATTCGGCGTTCACCCTGCCCGAGCTGATCGGGCTCACGGCC
GGAGCCGACGTCGTGCTTGACCCGGGAGATCATCAGCGAGTACTCGATGATCTGGCAATCGTTGCCGATCCGTTGACCAG
GAACAAGCTGGAGATCTTGAGCACGCTGGGGGACGGGTCGGCGCCTGCGCGACGAGTCGGGCGCCCGCGGATCCGGCTGG
CCTATCGGCTCACGCCGCGGCGCGTCCTCGGCCAGCGGCGGGCCGGCGGAGTTCAGTTCTCGGTCACCGGAACCGACGAG
CTGCGCCAACTGGATGCTGGCCTGGTGCTGACGTCGATTGGCTACCGCGGCAAGCCGATTCCCGACCTGCCGTTCGACGA
GCAGGCCGCGCTCGTGCCCAACGATGGTGGACGGGTCATCGACCCGGGCACCGGCGAGCCGGTGCCCGGCGCATACGTCG
CGGGTTGGATCAAGCGCGGGCCCACCGGGTTCATCGGCACGAACAAGTCCTGCTCTATGCAGACCGTTCAGGCGTTGGTG
GCCGACTTCAACGACGGCCGGCTGACCGATCCGGTGGCTACACCGACGGCGCTGGATCAGCTGGTGCAGGCCCGCCAGCC
CCAAGCCATCGGCTGTGCGGGATGGCGGGCCATCGACGCGGCCGAGATTGCGCGCGGCAGCGCCGACGGCCGGGTCCGCA
ACAAGTTCACCGACGTCGCCGAGATGCTCGCGGCAGCAACCAGCGCGCCTAAGGAACCGCTTCGGCGGCGCGTGCTGGCC
CGGCTGCGTGACCTGGGGCAGCCGATCGTGCTAACCGTCCCCTTGTGA

Upstream 100 bases:

>100_bases
ACTCTGCAAGATCGACGGCAAGCCGTCGCGCTACCGCAGCGAGCCGCAGCGTCAGCACTTGGCTGCCGCGCCGGCCGCAT
AGCTTGCTACGAGTGCACGC

Downstream 100 bases:

>100_bases
TGACATGGCGGCTTGGATCTCATCCATGTTGACCTCGCGCACCGGCTGGCCCAGCGACCAGTGGTGGCCGAACGGGTCGG
CGACCACCCCGTAGCGGTCT

Product: putative NADPH:adrenodoxin oxidoreductase fprB

Products: NA

Alternate protein names: FNR

Number of amino acids: Translated: 575; Mature: 574

Protein sequence:

>575_residues
MPHVITQSCCNDASCVFACPVNCIHPTPDEPGFATSEMLYIDPVACVDCGACVTACPVSAIAPNTRLDFEQLPFVEINAS
YYPKRPAGVKLAPTSKLAPVTPAAEVRVRRQPLTVAVVGSGPAAMYAADELLVQQGVQVNVFEKLPTPYGLVRSGVAPDH
QNTKRVTRLFDRIAGHRRFRFYLNVEIGKHLGHAELLAHHHAVLYAVGAPDDRRLTIDGMGLPGTGTATELVAWLNGHPD
FNDLPVDLSHERVVIIGNGNVALDVARVLAADPHELAATDIADHALSALRNSAVREVVVAARRGPAHSAFTLPELIGLTA
GADVVLDPGDHQRVLDDLAIVADPLTRNKLEILSTLGDGSAPARRVGRPRIRLAYRLTPRRVLGQRRAGGVQFSVTGTDE
LRQLDAGLVLTSIGYRGKPIPDLPFDEQAALVPNDGGRVIDPGTGEPVPGAYVAGWIKRGPTGFIGTNKSCSMQTVQALV
ADFNDGRLTDPVATPTALDQLVQARQPQAIGCAGWRAIDAAEIARGSADGRVRNKFTDVAEMLAAATSAPKEPLRRRVLA
RLRDLGQPIVLTVPL

Sequences:

>Translated_575_residues
MPHVITQSCCNDASCVFACPVNCIHPTPDEPGFATSEMLYIDPVACVDCGACVTACPVSAIAPNTRLDFEQLPFVEINAS
YYPKRPAGVKLAPTSKLAPVTPAAEVRVRRQPLTVAVVGSGPAAMYAADELLVQQGVQVNVFEKLPTPYGLVRSGVAPDH
QNTKRVTRLFDRIAGHRRFRFYLNVEIGKHLGHAELLAHHHAVLYAVGAPDDRRLTIDGMGLPGTGTATELVAWLNGHPD
FNDLPVDLSHERVVIIGNGNVALDVARVLAADPHELAATDIADHALSALRNSAVREVVVAARRGPAHSAFTLPELIGLTA
GADVVLDPGDHQRVLDDLAIVADPLTRNKLEILSTLGDGSAPARRVGRPRIRLAYRLTPRRVLGQRRAGGVQFSVTGTDE
LRQLDAGLVLTSIGYRGKPIPDLPFDEQAALVPNDGGRVIDPGTGEPVPGAYVAGWIKRGPTGFIGTNKSCSMQTVQALV
ADFNDGRLTDPVATPTALDQLVQARQPQAIGCAGWRAIDAAEIARGSADGRVRNKFTDVAEMLAAATSAPKEPLRRRVLA
RLRDLGQPIVLTVPL
>Mature_574_residues
PHVITQSCCNDASCVFACPVNCIHPTPDEPGFATSEMLYIDPVACVDCGACVTACPVSAIAPNTRLDFEQLPFVEINASY
YPKRPAGVKLAPTSKLAPVTPAAEVRVRRQPLTVAVVGSGPAAMYAADELLVQQGVQVNVFEKLPTPYGLVRSGVAPDHQ
NTKRVTRLFDRIAGHRRFRFYLNVEIGKHLGHAELLAHHHAVLYAVGAPDDRRLTIDGMGLPGTGTATELVAWLNGHPDF
NDLPVDLSHERVVIIGNGNVALDVARVLAADPHELAATDIADHALSALRNSAVREVVVAARRGPAHSAFTLPELIGLTAG
ADVVLDPGDHQRVLDDLAIVADPLTRNKLEILSTLGDGSAPARRVGRPRIRLAYRLTPRRVLGQRRAGGVQFSVTGTDEL
RQLDAGLVLTSIGYRGKPIPDLPFDEQAALVPNDGGRVIDPGTGEPVPGAYVAGWIKRGPTGFIGTNKSCSMQTVQALVA
DFNDGRLTDPVATPTALDQLVQARQPQAIGCAGWRAIDAAEIARGSADGRVRNKFTDVAEMLAAATSAPKEPLRRRVLAR
LRDLGQPIVLTVPL

Specific function: Unknown

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains

Homologues:

Organism=Homo sapiens, GI111118981, Length=486, Percent_Identity=39.5061728395062, Blast_Score=289, Evalue=4e-78,
Organism=Homo sapiens, GI111118983, Length=492, Percent_Identity=39.2276422764228, Blast_Score=284, Evalue=1e-76,
Organism=Escherichia coli, GI87082180, Length=159, Percent_Identity=32.0754716981132, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1789606, Length=165, Percent_Identity=29.6969696969697, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17543860, Length=440, Percent_Identity=31.8181818181818, Blast_Score=196, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6320584, Length=484, Percent_Identity=30.1652892561983, Blast_Score=182, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6320030, Length=262, Percent_Identity=27.4809160305344, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17137178, Length=445, Percent_Identity=34.8314606741573, Blast_Score=222, Evalue=5e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FPRB_MYCBO (P65529)

Other databases:

- EMBL:   BX248336
- RefSeq:   NP_854567.1
- ProteinModelPortal:   P65529
- EnsemblBacteria:   EBMYCT00000016684
- GeneID:   1092796
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb0910
- GeneTree:   EBGT00050000014581
- HOGENOM:   HBG522200
- OMA:   DRIKEVP
- ProtClustDB:   CLSK790809
- BioCyc:   MBOV233413:MB0910-MONOMER
- BRENDA:   1.18.1.2
- GO:   GO:0006810
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR013027
- InterPro:   IPR021163
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PIRSF:   PIRSF000362

Pfam domain/function: PF07992 Pyr_redox_2

EC number: =1.18.1.2

Molecular weight: Translated: 61338; Mature: 61207

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: PS00198 4FE4S_FER_1; PS51379 4FE4S_FER_2

Important sites: BINDING 123-123 BINDING 143-143 BINDING 151-151 BINDING 187-187 BINDING 213-213 BINDING 314-314 BINDING 456-456 BINDING 463-463

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHVITQSCCNDASCVFACPVNCIHPTPDEPGFATSEMLYIDPVACVDCGACVTACPVSA
CCCCCCHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEECCHHHHCCCHHHHHCCHHH
IAPNTRLDFEQLPFVEINASYYPKRPAGVKLAPTSKLAPVTPAAEVRVRRQPLTVAVVGS
CCCCCCCCHHHCCEEEECCCCCCCCCCCEEECCCCCCCCCCCHHHHEEECCCEEEEEECC
GPAAMYAADELLVQQGVQVNVFEKLPTPYGLVRSGVAPDHQNTKRVTRLFDRIAGHRRFR
CCHHHHHHHHHHHHCCCEEEEHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEE
FYLNVEIGKHLGHAELLAHHHAVLYAVGAPDDRRLTIDGMGLPGTGTATELVAWLNGHPD
EEEEEECCCCCCHHHHHHHCCEEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCC
FNDLPVDLSHERVVIIGNGNVALDVARVLAADPHELAATDIADHALSALRNSAVREVVVA
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARRGPAHSAFTLPELIGLTAGADVVLDPGDHQRVLDDLAIVADPLTRNKLEILSTLGDGS
HCCCCCCCCCCHHHHHHCCCCCCEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
APARRVGRPRIRLAYRLTPRRVLGQRRAGGVQFSVTGTDELRQLDAGLVLTSIGYRGKPI
CCHHHCCCCCEEEEEEECHHHHHCCCCCCCEEEEEECHHHHHHHHCCEEEEECCCCCCCC
PDLPFDEQAALVPNDGGRVIDPGTGEPVPGAYVAGWIKRGPTGFIGTNKSCSMQTVQALV
CCCCCCCCEEEEECCCCEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
ADFNDGRLTDPVATPTALDQLVQARQPQAIGCAGWRAIDAAEIARGSADGRVRNKFTDVA
HCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCHHHHHCCCCCCHHHHHHHHHH
EMLAAATSAPKEPLRRRVLARLRDLGQPIVLTVPL
HHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECC
>Mature Secondary Structure 
PHVITQSCCNDASCVFACPVNCIHPTPDEPGFATSEMLYIDPVACVDCGACVTACPVSA
CCCCCHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEECCHHHHCCCHHHHHCCHHH
IAPNTRLDFEQLPFVEINASYYPKRPAGVKLAPTSKLAPVTPAAEVRVRRQPLTVAVVGS
CCCCCCCCHHHCCEEEECCCCCCCCCCCEEECCCCCCCCCCCHHHHEEECCCEEEEEECC
GPAAMYAADELLVQQGVQVNVFEKLPTPYGLVRSGVAPDHQNTKRVTRLFDRIAGHRRFR
CCHHHHHHHHHHHHCCCEEEEHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEE
FYLNVEIGKHLGHAELLAHHHAVLYAVGAPDDRRLTIDGMGLPGTGTATELVAWLNGHPD
EEEEEECCCCCCHHHHHHHCCEEEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCC
FNDLPVDLSHERVVIIGNGNVALDVARVLAADPHELAATDIADHALSALRNSAVREVVVA
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARRGPAHSAFTLPELIGLTAGADVVLDPGDHQRVLDDLAIVADPLTRNKLEILSTLGDGS
HCCCCCCCCCCHHHHHHCCCCCCEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
APARRVGRPRIRLAYRLTPRRVLGQRRAGGVQFSVTGTDELRQLDAGLVLTSIGYRGKPI
CCHHHCCCCCEEEEEEECHHHHHCCCCCCCEEEEEECHHHHHHHHCCEEEEECCCCCCCC
PDLPFDEQAALVPNDGGRVIDPGTGEPVPGAYVAGWIKRGPTGFIGTNKSCSMQTVQALV
CCCCCCCCEEEEECCCCEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
ADFNDGRLTDPVATPTALDQLVQARQPQAIGCAGWRAIDAAEIARGSADGRVRNKFTDVA
HCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCHHHHHCCCCCCHHHHHHHHHH
EMLAAATSAPKEPLRRRVLARLRDLGQPIVLTVPL
HHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972