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The map label for this gene is purQ

Identifier: 121636713

GI number: 121636713

Start: 914542

End: 915216

Strand: Direct

Name: purQ

Synonym: BCG_0841

Alternate gene names: 121636713

Gene position: 914542-915216 (Clockwise)

Preceding gene: 121636712

Following gene: 121636718

Centisome position: 20.91

GC content: 65.93

Gene sequence:

>675_bases
GTGACGGCGCGCATCGGTGTCGTCACGTTTCCCGGCACGCTCGACGACGTCGACGCCGCGCGCGCGGCGCGGCAGGTGGG
CGCCGAGGTGGTCAGCCTGTGGCATGCCGACGCCGACCTTAAGGGTGTCGACGCCGTAGTGGTGCCCGGCGGATTTTCCT
ACGGTGACTACCTCCGGGCCGGAGCGATCGCCAGATTCGCTCCGGTGATGGACGAAGTGGTAGCTGCCGCGGACCGCGGC
ATGCCGGTGTTGGGGATTTGCAACGGCTTTCAGGTGCTGTGTGAGGCCGGGCTACTACCTGGTGCCCTGACCCGCAACGT
GGGATTGCACTTCATCTGCCGGGATGTGTGGCTGCGGGTAGCGTCGACGTCGACGGCGTGGACATCGCGTTTCGAGCCTG
ACGCCGACCTGTTGGTTCCGCTGAAGTCCGGCGAGGGCCGTTACGTGGCGCCGGAGAAGGTGCTTGACGAACTAGAAGGC
GAAGGCCGGGTGGTGTTCCGCTACCATGACAACGTCAACGGCTCGCTGCGCGACATCGCCGGCATCTGCTCAGCCAACGG
CCGTGTCGTCGGCCTGATGCCGCACCCCGAACATGCGATTGAAGCGTTGACCGGGCCGTCCGACGACGGACTGGGTCTGT
TCTATTCAGCGCTGGATGCCGTTCTGACGGGCTGA

Upstream 100 bases:

>100_bases
AGGTCGACGATACGGTTGATGACACCACGCTTGCCGAGATCGCAGAATCACTGTTGGCCAACACCGTGATCGAGGACTGG
ACGATCAGCCGGGACCCGCA

Downstream 100 bases:

>100_bases
GGTCACCCGCTCACGCTCACCCGGCGTCTCGCAGCAACGGCGGCGTCGCGGTTGGAGGTAATCCGGCTGCCGTCAGCTGA
CCGAAGAGCTCCGTCGCGGC

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTARIGVVTFPGTLDDVDAARAARQVGAEVVSLWHADADLKGVDAVVVPGGFSYGDYLRAGAIARFAPVMDEVVAAADRG
MPVLGICNGFQVLCEAGLLPGALTRNVGLHFICRDVWLRVASTSTAWTSRFEPDADLLVPLKSGEGRYVAPEKVLDELEG
EGRVVFRYHDNVNGSLRDIAGICSANGRVVGLMPHPEHAIEALTGPSDDGLGLFYSALDAVLTG

Sequences:

>Translated_224_residues
MTARIGVVTFPGTLDDVDAARAARQVGAEVVSLWHADADLKGVDAVVVPGGFSYGDYLRAGAIARFAPVMDEVVAAADRG
MPVLGICNGFQVLCEAGLLPGALTRNVGLHFICRDVWLRVASTSTAWTSRFEPDADLLVPLKSGEGRYVAPEKVLDELEG
EGRVVFRYHDNVNGSLRDIAGICSANGRVVGLMPHPEHAIEALTGPSDDGLGLFYSALDAVLTG
>Mature_223_residues
TARIGVVTFPGTLDDVDAARAARQVGAEVVSLWHADADLKGVDAVVVPGGFSYGDYLRAGAIARFAPVMDEVVAAADRGM
PVLGICNGFQVLCEAGLLPGALTRNVGLHFICRDVWLRVASTSTAWTSRFEPDADLLVPLKSGEGRYVAPEKVLDELEGE
GRVVFRYHDNVNGSLRDIAGICSANGRVVGLMPHPEHAIEALTGPSDDGLGLFYSALDAVLTG

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Escherichia coli, GI48994899, Length=231, Percent_Identity=28.1385281385281, Blast_Score=64, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24582111, Length=203, Percent_Identity=31.0344827586207, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24582109, Length=203, Percent_Identity=31.0344827586207, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17137292, Length=203, Percent_Identity=31.0344827586207, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURQ_MYCBO (P65903)

Other databases:

- EMBL:   BX248336
- RefSeq:   NP_854470.1
- ProteinModelPortal:   P65903
- SMR:   P65903
- EnsemblBacteria:   EBMYCT00000014737
- GeneID:   1092535
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb0812
- GeneTree:   EBGT00050000016355
- HOGENOM:   HBG302712
- OMA:   FPGTNCD
- ProtClustDB:   PRK03619
- BioCyc:   MBOV233413:MB0812-MONOMER
- BRENDA:   6.3.5.3
- GO:   GO:0005737
- HAMAP:   MF_00421
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR010075
- PIRSF:   PIRSF001586
- TIGRFAMs:   TIGR01737

Pfam domain/function: PF00117 GATase

EC number: =6.3.5.3

Molecular weight: Translated: 23633; Mature: 23502

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS51273 GATASE_TYPE_1; PS00442 GATASE_TYPE_I

Important sites: ACT_SITE 87-87 ACT_SITE 195-195 ACT_SITE 197-197

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARIGVVTFPGTLDDVDAARAARQVGAEVVSLWHADADLKGVDAVVVPGGFSYGDYLRA
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHH
GAIARFAPVMDEVVAAADRGMPVLGICNGFQVLCEAGLLPGALTRNVGLHFICRDVWLRV
HHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHH
ASTSTAWTSRFEPDADLLVPLKSGEGRYVAPEKVLDELEGEGRVVFRYHDNVNGSLRDIA
HCCCCHHHCCCCCCCCEEEEEECCCCCEECHHHHHHHHCCCCEEEEEEECCCCCCHHHHH
GICSANGRVVGLMPHPEHAIEALTGPSDDGLGLFYSALDAVLTG
HHHCCCCEEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TARIGVVTFPGTLDDVDAARAARQVGAEVVSLWHADADLKGVDAVVVPGGFSYGDYLRA
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHH
GAIARFAPVMDEVVAAADRGMPVLGICNGFQVLCEAGLLPGALTRNVGLHFICRDVWLRV
HHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHH
ASTSTAWTSRFEPDADLLVPLKSGEGRYVAPEKVLDELEGEGRVVFRYHDNVNGSLRDIA
HCCCCHHHCCCCCCCCEEEEEECCCCCEECHHHHHHHHCCCCEEEEEEECCCCCCHHHHH
GICSANGRVVGLMPHPEHAIEALTGPSDDGLGLFYSALDAVLTG
HHHCCCCEEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972