BacMap

Definition	Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome.
Accession	NC_008769
Length	4,374,522

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The map label for this gene is ydfG [C]

Identifier: 121636400

GI number: 121636400

Start: 603805

End: 604560

Strand: Reverse

Name: ydfG [C]

Synonym: BCG_0525c

Alternate gene names: 121636400

Gene position: 604560-603805 (Counterclockwise)

Preceding gene: 121636408

Following gene: 121636397

Centisome position: 13.82

GC content: 68.39

Gene sequence:

>756_bases
ATGACGACAATCGGCACCCGCAAGCGAGTCGCCGTGGTCACCGGCGCCAGTTCCGGTATCGGCGAGGCAACCGCGAGAAC
CCTTGCGGCCCAGGGGTTTCACGTGGTCGCGGTGGCGCGTCGGGCGGACCGGATCACCGCGCTGGCCAACCAGATCGGCG
GAACCGCAATTGTGGCCGATGTCACTGACGACGCCGCCGTCGAAGCGTTGGCCCGCGCGCTGAGCCGGGTGGACGTGCTG
GTCAACAACGCCGGTGGCGCCAAGGGGCTTCAGTTCGTCGCCGATGCCGATTTGGAGCACTGGCGATGGATGTGGGACAC
CAACGTACTGGGCACGCTGCGGGTAACCCGCGCGCTGCTGCCCAAGCTGATCGACTCCGGCGACGGCCTGATCGTCACCG
TCACCTCGATCGCCGCGCTCGAGGTGTACGACGGCGGCGCCGGCTACACCGCTGCCAAGCACGCGCAGGGCGCGCTGCAT
CGCACGCTGCGCGGCGAACTGCTGGGGAAGCCGGTCCGGCTCACGGAGATCGCTCCAGGCGCGGTCGAGACCGAATTTTC
GCTGGTCCGCTTCGACGGCGACCAGCAACGCGCGGACGCGGTTTATGCCGGCATGACACCGCTAGTAGCCGCCGACGTCG
CCGAGGTGATCGGATTCGTGGCCACCCGGCCCTCACACGTCAACCTTGACCAGATCGTCATCCGGCCCCGCGACCAGGCA
TCAGCTAGCCGTCGCGCTACCCACCCGGTCCGTTAG

Upstream 100 bases:

>100_bases
CGGCAACAACACGCGCCCGCGAAAAGACACGCGGTCGTCGTGCGGAACAAGGCGCTGTGGTACACACCGAGAATTTAGCA
CGTTTATTAGAGTTGTCCCG

Downstream 100 bases:

>100_bases
TAGTCGTGGGTGTGCCGGACGGGGTGGGGGCATCCGACGGCGTGACCGGGGCGGTGACCGGGATTTGCGTCGCCGCCGGT
TTGGCCGCCGGTGGCGGTAG

Product: putative short-chain type oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVEALARALSRVDVL
VNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGDGLIVTVTSIAALEVYDGGAGYTAAKHAQGALH
RTLRGELLGKPVRLTEIAPGAVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA
SASRRATHPVR

Sequences:

>Translated_251_residues
MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVEALARALSRVDVL
VNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGDGLIVTVTSIAALEVYDGGAGYTAAKHAQGALH
RTLRGELLGKPVRLTEIAPGAVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA
SASRRATHPVR
>Mature_250_residues
TTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVADVTDDAAVEALARALSRVDVLV
NNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALLPKLIDSGDGLIVTVTSIAALEVYDGGAGYTAAKHAQGALHR
TLRGELLGKPVRLTEIAPGAVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQAS
ASRRATHPVR

Specific function: Unknown

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=252, Percent_Identity=34.1269841269841, Blast_Score=117, Evalue=9e-27,
Organism=Homo sapiens, GI7706318, Length=189, Percent_Identity=35.4497354497354, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI20149619, Length=233, Percent_Identity=30.4721030042918, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI32483357, Length=201, Percent_Identity=31.3432835820896, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI40254992, Length=186, Percent_Identity=32.7956989247312, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI7657478, Length=190, Percent_Identity=32.1052631578947, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI5031737, Length=197, Percent_Identity=34.010152284264, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI4557649, Length=185, Percent_Identity=29.7297297297297, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=34.0314136125654, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI40548397, Length=253, Percent_Identity=26.8774703557312, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI214010158, Length=253, Percent_Identity=26.8774703557312, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI214010156, Length=253, Percent_Identity=26.8774703557312, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI22758144, Length=253, Percent_Identity=26.8774703557312, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI10190704, Length=207, Percent_Identity=28.9855072463768, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI126723191, Length=177, Percent_Identity=30.5084745762712, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI4758504, Length=194, Percent_Identity=32.9896907216495, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787820, Length=240, Percent_Identity=37.9166666666667, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1787335, Length=196, Percent_Identity=32.1428571428571, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1786701, Length=187, Percent_Identity=33.1550802139037, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI87082100, Length=189, Percent_Identity=35.978835978836, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787905, Length=186, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788459, Length=191, Percent_Identity=29.8429319371728, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI87082160, Length=202, Percent_Identity=27.2277227722772, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI2367175, Length=195, Percent_Identity=32.3076923076923, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=242, Percent_Identity=30.5785123966942, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71997402, Length=195, Percent_Identity=30.7692307692308, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=261, Percent_Identity=27.9693486590038, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=242, Percent_Identity=29.7520661157025, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=30.5019305019305, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17570069, Length=204, Percent_Identity=29.9019607843137, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=257, Percent_Identity=30.3501945525292, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=198, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=244, Percent_Identity=28.2786885245902, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=194, Percent_Identity=31.9587628865979, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=254, Percent_Identity=29.9212598425197, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=239, Percent_Identity=29.2887029288703, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=238, Percent_Identity=26.4705882352941, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=197, Percent_Identity=28.9340101522843, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=242, Percent_Identity=28.5123966942149, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=190, Percent_Identity=27.3684210526316, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=241, Percent_Identity=27.8008298755187, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=278, Percent_Identity=27.3381294964029, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=196, Percent_Identity=29.5918367346939, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=246, Percent_Identity=27.6422764227642, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=244, Percent_Identity=28.6885245901639, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=247, Percent_Identity=26.7206477732794, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=248, Percent_Identity=37.0967741935484, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6322067, Length=194, Percent_Identity=33.5051546391753, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322227, Length=192, Percent_Identity=28.6458333333333, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322226, Length=188, Percent_Identity=28.1914893617021, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=191, Percent_Identity=28.2722513089005, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI116007236, Length=247, Percent_Identity=35.6275303643725, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24641232, Length=250, Percent_Identity=31.6, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI23397609, Length=228, Percent_Identity=33.7719298245614, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI28571387, Length=248, Percent_Identity=31.8548387096774, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281364494, Length=249, Percent_Identity=29.718875502008, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24641388, Length=250, Percent_Identity=33.6, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24648944, Length=244, Percent_Identity=32.3770491803279, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24648693, Length=248, Percent_Identity=31.0483870967742, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21355889, Length=248, Percent_Identity=31.0483870967742, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357041, Length=235, Percent_Identity=31.4893617021277, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=29.0816326530612, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24663911, Length=251, Percent_Identity=30.6772908366534, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI116007234, Length=249, Percent_Identity=30.9236947791165, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=30.8641975308642, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI116007238, Length=176, Percent_Identity=35.7954545454545, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571526, Length=190, Percent_Identity=33.1578947368421, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21355319, Length=205, Percent_Identity=29.2682926829268, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=31.25, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=31.25, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24580925, Length=206, Percent_Identity=28.6407766990291, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24639444, Length=235, Percent_Identity=29.7872340425532, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17737361, Length=196, Percent_Identity=30.6122448979592, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI18859837, Length=161, Percent_Identity=34.7826086956522, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24644339, Length=188, Percent_Identity=27.1276595744681, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26416; Mature: 26285

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCEEEEEE
VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL
CCCHHHHHHHHHHHHHHHHEEECCCCCCCEEEEECCCHHHHEEEECCCCHHHHHHHHHHH
PKLIDSGDGLIVTVTSIAALEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG
HHHHCCCCCEEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA
CCCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHEEECCCCHH
SASRRATHPVR
HHHHCCCCCCC
>Mature Secondary Structure 
TTIGTRKRVAVVTGASSGIGEATARTLAAQGFHVVAVARRADRITALANQIGGTAIVAD
CCCCCCCEEEEEECCCCCCCHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCEEEEEE
VTDDAAVEALARALSRVDVLVNNAGGAKGLQFVADADLEHWRWMWDTNVLGTLRVTRALL
CCCHHHHHHHHHHHHHHHHEEECCCCCCCEEEEECCCHHHHEEEECCCCHHHHHHHHHHH
PKLIDSGDGLIVTVTSIAALEVYDGGAGYTAAKHAQGALHRTLRGELLGKPVRLTEIAPG
HHHHCCCCCEEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
AVETEFSLVRFDGDQQRADAVYAGMTPLVAADVAEVIGFVATRPSHVNLDQIVIRPRDQA
CCCCCEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHEEECCCCHH
SASRRATHPVR
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]