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The map label for this gene is coxS [H]

Identifier: 121636287

GI number: 121636287

Start: 482613

End: 483092

Strand: Reverse

Name: coxS [H]

Synonym: BCG_0412c

Alternate gene names: 121636287

Gene position: 483092-482613 (Counterclockwise)

Preceding gene: 121636288

Following gene: 121636286

Centisome position: 11.04

GC content: 65.0

Gene sequence:

>480_bases
ATGCAGGTGAACATGACGGTAAACGGCGAGCCCGTCACCGCCGAGGTCGAACCCCGGATGCTGCTGGTCCATTTTCTCCG
TGATCAGCTGCGGCTCACCGGAACTCACTGGGGCTGTGATACCAGCAACTGCGGGACATGCGTGGTGGAGGTCGACGGCG
TGCCGGTGAAATCCTGCACGATGCTCGCCGTGATGGCCTCCGGGCACAGCATCCGCACGGTAGAGGGCTTGGCTGGGCCC
GACGGCCAGCTCGACCCGGTGCAGGAAGGGTTCATGCGCTGCCACGGGCTGCAATGCGGCTTCTGCACCCCGGGAATGCT
GATTACCGCGCGCGCCCTGCTGGACCGCAACCCGGATCCCGACGAGCAGACCATCCGGGAAGCGATCTCGGGGCAGATCT
GCCGGTGCACCGGATACACCACGATCGTGCGCTCCATTCAGTGGGCGGCAGCACACCAGACCGTAAAGGCGCAGTCATGA

Upstream 100 bases:

>100_bases
GGCACCTCGCCGGTGAACTGACCGTTCGCACGCTGCGCACCGCCGCCGGGCGCGTGCTCGGCGCGCCGGCGGCCCCCGAG
GCCTGAGAGGGGAACCAACC

Downstream 100 bases:

>100_bases
CAACGATCGAGTCACGCCCTCCGTCGCCGGAAGACCTAGCCGACAACGCTCAGCAGCCGTGCGGGCACGGCCGGATGATG
CGCAAAGAGGACCCGCGATT

Product: putative carbon monoxyde dehydrogenase (small chain)

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MQVNMTVNGEPVTAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNCGTCVVEVDGVPVKSCTMLAVMASGHSIRTVEGLAGP
DGQLDPVQEGFMRCHGLQCGFCTPGMLITARALLDRNPDPDEQTIREAISGQICRCTGYTTIVRSIQWAAAHQTVKAQS

Sequences:

>Translated_159_residues
MQVNMTVNGEPVTAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNCGTCVVEVDGVPVKSCTMLAVMASGHSIRTVEGLAGP
DGQLDPVQEGFMRCHGLQCGFCTPGMLITARALLDRNPDPDEQTIREAISGQICRCTGYTTIVRSIQWAAAHQTVKAQS
>Mature_159_residues
MQVNMTVNGEPVTAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNCGTCVVEVDGVPVKSCTMLAVMASGHSIRTVEGLAGP
DGQLDPVQEGFMRCHGLQCGFCTPGMLITARALLDRNPDPDEQTIREAISGQICRCTGYTTIVRSIQWAAAHQTVKAQS

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=148, Percent_Identity=38.5135135135135, Blast_Score=93, Evalue=1e-19,
Organism=Homo sapiens, GI91823271, Length=152, Percent_Identity=36.8421052631579, Blast_Score=86, Evalue=2e-17,
Organism=Escherichia coli, GI1786480, Length=165, Percent_Identity=38.7878787878788, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1789232, Length=151, Percent_Identity=38.4105960264901, Blast_Score=103, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17540638, Length=149, Percent_Identity=40.2684563758389, Blast_Score=120, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI32566215, Length=152, Percent_Identity=37.5, Blast_Score=106, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17539860, Length=151, Percent_Identity=35.7615894039735, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17737937, Length=152, Percent_Identity=36.8421052631579, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24647201, Length=164, Percent_Identity=31.7073170731707, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24647199, Length=163, Percent_Identity=30.0613496932515, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24647195, Length=170, Percent_Identity=30.5882352941176, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24647197, Length=170, Percent_Identity=30.5882352941176, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24647193, Length=170, Percent_Identity=27.6470588235294, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 17215; Mature: 17215

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
10.1 %Cys+Met (Translated Protein)
5.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
10.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVNMTVNGEPVTAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNCGTCVVEVDGVPVKSCT
CEEEEEECCCEEEEECCHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEEEECCCCCCHHH
MLAVMASGHSIRTVEGLAGPDGQLDPVQEGFMRCHGLQCGFCTPGMLITARALLDRNPDP
EEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCC
DEQTIREAISGQICRCTGYTTIVRSIQWAAAHQTVKAQS
CHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHCEECCCC
>Mature Secondary Structure
MQVNMTVNGEPVTAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNCGTCVVEVDGVPVKSCT
CEEEEEECCCEEEEECCHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEEEECCCCCCHHH
MLAVMASGHSIRTVEGLAGPDGQLDPVQEGFMRCHGLQCGFCTPGMLITARALLDRNPDP
EEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCC
DEQTIREAISGQICRCTGYTTIVRSIQWAAAHQTVKAQS
CHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 10430865; 12475995 [H]