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The map label for this gene is eriC [C]

Identifier: 121636055

GI number: 121636055

Start: 198601

End: 200079

Strand: Reverse

Name: eriC [C]

Synonym: BCG_0179c

Alternate gene names: 121636055

Gene position: 200079-198601 (Counterclockwise)

Preceding gene: 121636062

Following gene: 121636053

Centisome position: 4.57

GC content: 67.21

Gene sequence:

>1479_bases
ATGGCGCCGGGCGACTGGTCGGTGTTCGCTTGGCATGCTGCTAACCTCCCGACCATGCCGGAGGCGGAAGACATCGGGAA
CGAGGCCGCCGGCGGACGACTCGGCGTATCGATCAGGAGCGCGGGCTACCTGCGCAAATGGTTCCTGCTAGGCATCACGA
TCGGTGTCATTGCCGGCCTGGGCGCCGTCGTCTTCTACCTCGCGCTGAAATACACCAGCGAGTTTCTGCTCGGCTACCTC
GCGGACTATCAGATTCCCACTCCCGTTGGGGAGGGCGGCCACCGCGGGTCCACCGGTTTCGCGCGTCCGTGGGCGATTCC
GCTGGTGACGACGGGCGGGGCGGTGCTGTCGGCATTGATCGTGGCCAAGCTCGCCCCGGAGGCCACCGGTCACGGCACCG
ACGAAGCGATCGAGTCGGTGCACGGCGATCCGCGCGCCATCCGAGGTCGGGCGGTGCTGGTGAAGATGGTGGCCAGCGCC
TTGACCATCGGCTCGGGCGGTTCAGGCGGCCGCGAAGGCCCGACCGCGCAGATCTCGGCCGGCTTCTGCTCACTGCTGAC
CCGCCGGCTGAACCTGTCCAACGAAGACGGCCGGACCGCGGTAGCGCTGGGTATCGGCGCCGGCATCGGCGCCATCTTCG
CTGCGCCACTGGGCGGAGCGGCGTTGGGCGCCTCGATCCCCTACCGCGACGACTTCGACTACCGCAACCTGCTGCCGGGT
TTCATCGCCTCGGGAACCGCCTACGCCGTGCTCGGCGCCTTCTTGGGCTTCGACCCGCTGTTCGGCTACATCGACGCCGA
GTATCGCTTCGAAAAGGCGTGGCCACTACTGTGGTTCGTGGTGATCGGGCTGATCGCAGCCGCCGTAGGCTACTTGTATG
CCCGAGTCTTTCACGCGTCGGTGGCAATTACGCGCCGGCTGCCCGGGGGCCCGGTGCTCAAACCGGCGATCGGCGGACTG
CTGGTCGGGCTGTTAGGTCTGCCGATTCCCCAGATCCTGAGCAGCGGCTATGGCTGGGCGCAGCTAGCCGCCGATCGGGG
GACGCTGCTGAGCATCCCGTTGTGGATCGTCATCGTCTTGCCGATCGCCAAGATCCTCGCGACGTCGCTGTCGATCGGCA
CCGGCGGATCAGGCGGGCTATTCGGGCCGGGAATCGTGATCGGCGCCTTCGTCGGAGCGGCGATCTGGCGGCTAGGCGAG
CTCACCGAGCTGCCCGGGGTGCCCCACGAGCCGGGCATCTTCGTCGTGGTCGCAATGATGGCGTGCTTCGGCAGTGTCTC
CCGCGCGCCGCTGGCCGTCATGATCATGGTCGCTGAGATGACCGGCTCGTTCTCGGTGGTGCCTGGAGCGATCATCGCCG
TCGGTATCGCGGCACTGTTGTTGTCTCGCACCAACGTCACCATCTACGAGACGCAGCGACTGAACCGGCAGACCGCCGAG
GCCGAACGCGGAGGCAGTGATCGGCCGACAACGGCTTAG

Upstream 100 bases:

>100_bases
GTTTCGGATCTCCTCGCCGCACAGCGGCGGTGATCGCGTACGTCCAGACCTGGGCCATGGTTGCGCTGCTGATCGTCGGA
TAGCGCTGGCCAACTCTGGG

Downstream 100 bases:

>100_bases
CGGCGCCGGCAGCCGATCTGGCGGGAATCGGGGCGCCGGACCGAGCAAGATCCCCGTCAAACTCCCCTACAGCGCCCGGA
TGTTCTGTACCGGCAGCCGG

Product: putative transmembrane protein

Products: Cl Ion [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRLGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYL
ADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASA
LTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG
FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGL
LVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGE
LTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE
AERGGSDRPTTA

Sequences:

>Translated_492_residues
MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRLGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYL
ADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASA
LTIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG
FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGL
LVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGE
LTELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE
AERGGSDRPTTA
>Mature_491_residues
APGDWSVFAWHAANLPTMPEAEDIGNEAAGGRLGVSIRSAGYLRKWFLLGITIGVIAGLGAVVFYLALKYTSEFLLGYLA
DYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALIVAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASAL
TIGSGGSGGREGPTAQISAGFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPGF
IASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHASVAITRRLPGGPVLKPAIGGLL
VGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVLPIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGEL
TELPGVPHEPGIFVVVAMMACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAEA
ERGGSDRPTTA

Specific function: Selective chloride channel [C]

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family [H]

Homologues:

Organism=Escherichia coli, GI1786350, Length=363, Percent_Identity=29.4765840220386, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081943, Length=360, Percent_Identity=27.5, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 50775; Mature: 50644

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPGDWSVFAWHAANLPTMPEAEDIGNEAAGGRLGVSIRSAGYLRKWFLLGITIGVIAGL
CCCCCCCEEEEECCCCCCCCCHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHH
GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHH
VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA
HHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHH
GFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG
HHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHCCCCCHHHCCCCCCCCCCCHHHHCCH
FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHAS
HHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL
HHHEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHCCCCCEEHHHHHHHHHH
PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
ACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE
HHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHH
AERGGSDRPTTA
HHCCCCCCCCCC
>Mature Secondary Structure 
APGDWSVFAWHAANLPTMPEAEDIGNEAAGGRLGVSIRSAGYLRKWFLLGITIGVIAGL
CCCCCCEEEEECCCCCCCCCHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHH
GAVVFYLALKYTSEFLLGYLADYQIPTPVGEGGHRGSTGFARPWAIPLVTTGGAVLSALI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHH
VAKLAPEATGHGTDEAIESVHGDPRAIRGRAVLVKMVASALTIGSGGSGGREGPTAQISA
HHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHH
GFCSLLTRRLNLSNEDGRTAVALGIGAGIGAIFAAPLGGAALGASIPYRDDFDYRNLLPG
HHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHCCCCCHHHCCCCCCCCCCCHHHHCCH
FIASGTAYAVLGAFLGFDPLFGYIDAEYRFEKAWPLLWFVVIGLIAAAVGYLYARVFHAS
HHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAITRRLPGGPVLKPAIGGLLVGLLGLPIPQILSSGYGWAQLAADRGTLLSIPLWIVIVL
HHHEECCCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHCCCCCEEHHHHHHHHHH
PIAKILATSLSIGTGGSGGLFGPGIVIGAFVGAAIWRLGELTELPGVPHEPGIFVVVAMM
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
ACFGSVSRAPLAVMIMVAEMTGSFSVVPGAIIAVGIAALLLSRTNVTIYETQRLNRQTAE
HHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHH
AERGGSDRPTTA
HHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Cl Ion [Periplasm] [C]

Specific reaction: Cl Ion [Periplasm] = Cl Ion [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]