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The map label for this gene is sdaA

Identifier: 121635980

GI number: 121635980

Start: 105933

End: 107318

Strand: Reverse

Name: sdaA

Synonym: BCG_0100c

Alternate gene names: 121635980

Gene position: 107318-105933 (Counterclockwise)

Preceding gene: 121635981

Following gene: 121635978

Centisome position: 2.45

GC content: 65.08

Gene sequence:

>1386_bases
ATGACCATCAGCGTCTTCGACCTGTTCACCATCGGCATCGGGCCGTCCAGTTCCCACACCGTGGGACCGATGCGCGCGGC
AAACCAGTTCGTAGTTGCGCTGCGCCGCCGGGGCCACCTGGATGACCTCGAGGCGATGCGAGTGGATCTGTTCGGCTCGC
TCGCGGCCACCGGAGCCGGTCATGGCACCATGTCGGCGATATTGCTGGGGCTGGAAGGCTGCCAGCCAGAAACGATTACC
ACCGAACACAAGGAACGCCGGCTCGCCGAGATCGCAGCGTCCGGCGTGACGCGAATCGGCGGTGTCATTCCGGTCCCGCT
GACCGAGCGTGATATCGACCTGCATCCCGACATCGTTCTGCCAACGCATCCCAACGGAATGACGTTCACTGCCGCGGGCC
CACACGGCCGCGTCTTGGCCACCGAGACTTATTTTTCGGTGGGCGGAGGGTTCATCGTCACGGAACAGACCAGCGGCAAC
AGCGGCCAACATCCATGCTCAGTTGCCCTTCCCTACGTGTCGGCCCAAGAACTGCTGGACATCTGTGACCGCCTCGACGT
GTCAATTAGCGAAGCGGCGCTGCGCAACGAAACATGTTGCCGCACCGAGAACGAGGTACGCGCCGCGCTGCTGCACCTGC
GCGACGTCATGGTTGAGTGCGAACAGCGGAGCATCGCTCGCGAAGGGTTGCTTCCTGGCGGCCTCCGGGTGCGCCGGCGA
GCGAAGGTGTGGTATGACCGCTTGAACGCCGAAGACCCCACTCGCAAGCCGGAATTCGCTGAGGACTGGGTCAACCTGGT
CGCGCTGGCAGTCAACGAGGAGAACGCCTCCGGTGGGCGCGTCGTCACCGCCCCGACCAACGGTGCCGCCGGCATCGTGC
CGGCGGTCCTGCACTACGCAATCCACTACACGTCGGCCGGCGCGGGGGACCCCGACGATGTCACCGTGCGATTCCTGCTC
ACTGCTGGAGCCATCGGATCGTTGTTCAAGGAGCGAGCATCGATCTCCGGAGCCGAGGTCGGCTGTCAGGGCGAGGTCGG
CTCCGCGGCCGCCATGGCCGCCGCCGGATTGGCTGAAATCCTCGGCGGCACACCGCGACAAGTGGAAAACGCCGCCGAGA
TCGCCATGGAACACAGCCTCGGCCTGACCTGTGACCCCATCGCCGGGCTGGTGCAGATCCCCTGCATCGAACGCAACGCG
ATTTCCGCCGGCAAGGCCATCAACGCCGCACGGATGGCATTGCGCGGCGACGGCATCCATCGCGTCACCCTCGACCAGGT
CATCGACACCATGCGCGCCACCGGCGCGGACATGCACACCAAGTACAAGGAAACCTCGGCCGGCGGGCTCGCCATCAACG
TCGCAGTCAACATCGTCGAGTGTTGA

Upstream 100 bases:

>100_bases
CGGCACTGACGGCCACCAACGACGACCAGCTGGGTCCGCTGCGCGCCCAGGTCCAGCGGCTGGCCGCACGCTATCCGCTC
TACCCGGAACTGCACCGGAC

Downstream 100 bases:

>100_bases
CCAACCGTTGCCGTTGAGTCCGGCTCATCCGACGGGATAGACGACCCCGGTGAGCTCTTCGGACACAGCCCACAGGCGGC
GCTGCAGCTGCTCGTCGTGA

Product: putative l-serine dehydratase sdaA

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MTISVFDLFTIGIGPSSSHTVGPMRAANQFVVALRRRGHLDDLEAMRVDLFGSLAATGAGHGTMSAILLGLEGCQPETIT
TEHKERRLAEIAASGVTRIGGVIPVPLTERDIDLHPDIVLPTHPNGMTFTAAGPHGRVLATETYFSVGGGFIVTEQTSGN
SGQHPCSVALPYVSAQELLDICDRLDVSISEAALRNETCCRTENEVRAALLHLRDVMVECEQRSIAREGLLPGGLRVRRR
AKVWYDRLNAEDPTRKPEFAEDWVNLVALAVNEENASGGRVVTAPTNGAAGIVPAVLHYAIHYTSAGAGDPDDVTVRFLL
TAGAIGSLFKERASISGAEVGCQGEVGSAAAMAAAGLAEILGGTPRQVENAAEIAMEHSLGLTCDPIAGLVQIPCIERNA
ISAGKAINAARMALRGDGIHRVTLDQVIDTMRATGADMHTKYKETSAGGLAINVAVNIVEC

Sequences:

>Translated_461_residues
MTISVFDLFTIGIGPSSSHTVGPMRAANQFVVALRRRGHLDDLEAMRVDLFGSLAATGAGHGTMSAILLGLEGCQPETIT
TEHKERRLAEIAASGVTRIGGVIPVPLTERDIDLHPDIVLPTHPNGMTFTAAGPHGRVLATETYFSVGGGFIVTEQTSGN
SGQHPCSVALPYVSAQELLDICDRLDVSISEAALRNETCCRTENEVRAALLHLRDVMVECEQRSIAREGLLPGGLRVRRR
AKVWYDRLNAEDPTRKPEFAEDWVNLVALAVNEENASGGRVVTAPTNGAAGIVPAVLHYAIHYTSAGAGDPDDVTVRFLL
TAGAIGSLFKERASISGAEVGCQGEVGSAAAMAAAGLAEILGGTPRQVENAAEIAMEHSLGLTCDPIAGLVQIPCIERNA
ISAGKAINAARMALRGDGIHRVTLDQVIDTMRATGADMHTKYKETSAGGLAINVAVNIVEC
>Mature_460_residues
TISVFDLFTIGIGPSSSHTVGPMRAANQFVVALRRRGHLDDLEAMRVDLFGSLAATGAGHGTMSAILLGLEGCQPETITT
EHKERRLAEIAASGVTRIGGVIPVPLTERDIDLHPDIVLPTHPNGMTFTAAGPHGRVLATETYFSVGGGFIVTEQTSGNS
GQHPCSVALPYVSAQELLDICDRLDVSISEAALRNETCCRTENEVRAALLHLRDVMVECEQRSIAREGLLPGGLRVRRRA
KVWYDRLNAEDPTRKPEFAEDWVNLVALAVNEENASGGRVVTAPTNGAAGIVPAVLHYAIHYTSAGAGDPDDVTVRFLLT
AGAIGSLFKERASISGAEVGCQGEVGSAAAMAAAGLAEILGGTPRQVENAAEIAMEHSLGLTCDPIAGLVQIPCIERNAI
SAGKAINAARMALRGDGIHRVTLDQVIDTMRATGADMHTKYKETSAGGLAINVAVNIVEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family

Homologues:

Organism=Escherichia coli, GI1788116, Length=463, Percent_Identity=50.9719222462203, Blast_Score=417, Evalue=1e-118,
Organism=Escherichia coli, GI48994925, Length=456, Percent_Identity=50.8771929824561, Blast_Score=407, Evalue=1e-115,
Organism=Escherichia coli, GI1789161, Length=457, Percent_Identity=50.54704595186, Blast_Score=407, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SDHL_MYCBO (P66774)

Other databases:

- EMBL:   BX248334
- RefSeq:   NP_853739.1
- ProteinModelPortal:   P66774
- SMR:   P66774
- EnsemblBacteria:   EBMYCT00000016408
- GeneID:   1093594
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb0070c
- GeneTree:   EBGT00050000018290
- HOGENOM:   HBG304565
- OMA:   WAAMREC
- ProtClustDB:   CLSK790234
- BioCyc:   MBOV233413:MB0070C-MONOMER
- BRENDA:   4.3.1.17
- GO:   GO:0006094
- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131
- TIGRFAMs:   TIGR00720

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta

EC number: =4.3.1.17

Molecular weight: Translated: 48577; Mature: 48446

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISVFDLFTIGIGPSSSHTVGPMRAANQFVVALRRRGHLDDLEAMRVDLFGSLAATGAG
CEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
HGTMSAILLGLEGCQPETITTEHKERRLAEIAASGVTRIGGVIPVPLTERDIDLHPDIVL
CHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCEEE
PTHPNGMTFTAAGPHGRVLATETYFSVGGGFIVTEQTSGNSGQHPCSVALPYVSAQELLD
ECCCCCEEEEECCCCCCEEEEEEEEECCCCEEEEECCCCCCCCCCCEEEECCCCHHHHHH
ICDRLDVSISEAALRNETCCRTENEVRAALLHLRDVMVECEQRSIAREGLLPGGLRVRRR
HHHHCCCCHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
AKVWYDRLNAEDPTRKPEFAEDWVNLVALAVNEENASGGRVVTAPTNGAAGIVPAVLHYA
HHHHHHHCCCCCCCCCCCHHHHHHHEEEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHH
IHYTSAGAGDPDDVTVRFLLTAGAIGSLFKERASISGAEVGCQGEVGSAAAMAAAGLAEI
HHCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
LGGTPRQVENAAEIAMEHSLGLTCDPIAGLVQIPCIERNAISAGKAINAARMALRGDGIH
HCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHCCCCCE
RVTLDQVIDTMRATGADMHTKYKETSAGGLAINVAVNIVEC
EEEHHHHHHHHHHCCCCHHHHHCCCCCCCEEEEEEEEEECC
>Mature Secondary Structure 
TISVFDLFTIGIGPSSSHTVGPMRAANQFVVALRRRGHLDDLEAMRVDLFGSLAATGAG
EEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
HGTMSAILLGLEGCQPETITTEHKERRLAEIAASGVTRIGGVIPVPLTERDIDLHPDIVL
CHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCEEE
PTHPNGMTFTAAGPHGRVLATETYFSVGGGFIVTEQTSGNSGQHPCSVALPYVSAQELLD
ECCCCCEEEEECCCCCCEEEEEEEEECCCCEEEEECCCCCCCCCCCEEEECCCCHHHHHH
ICDRLDVSISEAALRNETCCRTENEVRAALLHLRDVMVECEQRSIAREGLLPGGLRVRRR
HHHHCCCCHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
AKVWYDRLNAEDPTRKPEFAEDWVNLVALAVNEENASGGRVVTAPTNGAAGIVPAVLHYA
HHHHHHHCCCCCCCCCCCHHHHHHHEEEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHH
IHYTSAGAGDPDDVTVRFLLTAGAIGSLFKERASISGAEVGCQGEVGSAAAMAAAGLAEI
HHCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
LGGTPRQVENAAEIAMEHSLGLTCDPIAGLVQIPCIERNAISAGKAINAARMALRGDGIH
HCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHCCCCCE
RVTLDQVIDTMRATGADMHTKYKETSAGGLAINVAVNIVEC
EEEHHHHHHHHHHCCCCHHHHHCCCCCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972