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The map label for this gene is ttdR [H]

Identifier: 121610128

GI number: 121610128

Start: 3553915

End: 3554838

Strand: Direct

Name: ttdR [H]

Synonym: Veis_3187

Alternate gene names: 121610128

Gene position: 3553915-3554838 (Clockwise)

Preceding gene: 121610126

Following gene: 121610129

Centisome position: 63.84

GC content: 59.31

Gene sequence:

>924_bases
ATGAGTGGCAGCGGCATCCAGCCAGCCGATTTTGGCTTTTTCTCCACACTTGCAACCGCTGGCAGCCTGAGCGCTGCTGC
TCGTGAATTGGGCATTACGACGCCTGCGGTCAGCAAGCATCTGGCATCGATGGAGTCGCGCATGGGCGTGACTTTGGTAA
ACCGCACGACGCGCCGCATGAGTCTCACCCCGGAGGGAGAGGTGTATTTGGAGCATGCACGCCGAATCCTCAGCGACATC
GACGGCTTGGAGCAATTGATCCATGGCGCAACAACCTCCGCCAGGGGGCTGTTGAGAGTGAATGCGACACCCGGTTTCGG
CCGCAGTCATATCGCGCCCCTCGTTTCAAAGTTCATCTTCGGGCATCCCGGCGTCGAAGTGCAGCTTCAACTGTCGGTCA
ATCCACCGCCGTTGACCGAGGACTCGTTCGATGTCTGCATTCGTTTTGGTTCACCCCCTGATGCCCGGGTCATCGCCAGG
CACATCGCCCCCAATCGCCGTCTTCTGTGCGCGTCTCCGGTGTATATCGCCAAGCATGGTTTGCCCGAAGTTCCGCGCGA
CCTGACACGGCATAACTGCATCGGTATTCGCCAGGGGGATGAAGCCTATGGGGTGTGGCGATTGACAAGTGGCTGCGGTC
GATTCAGTACCACCGAGGTCGTCAAAACCAGAGGCAACCTGACGACCAACGACGGCGAAATAGCGGTGAATTGGGCACTG
GACGGTCACGGCATTCTGATGCGCGCCGAGTGGGACATCGAGAGGTATTTGAAGAGCGGACGGCTTGTACAAGTCCTGCC
GCAGTGCCACACGCCCGATGCGAACATCCATGCCGTTTATCCCAAGCGGCATCAAAATGCCGGGAGGGTACGGGCGTTCG
TGGAGTTCATCACCCGCTCCCTGACGCCGAACCTTGCCCCTTGA

Upstream 100 bases:

>100_bases
CTGTACGGATCGTTGATAGCGGCACTGTAAGAACTGGACGCCCCGATGCAACGTCGTTAAAGTCAATCCATTGTTTACTT
GAAATCAACGACAAGACATC

Downstream 100 bases:

>100_bases
TCCGACAACAAACCCGGCATCCATGCGGGTTTCGCCCTTTTGGGCACCAGGACACGACCCCCTCTGCACCGAGGTGGTTG
ATAAACTGCTTGGGCACGAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSGSGIQPADFGFFSTLATAGSLSAAARELGITTPAVSKHLASMESRMGVTLVNRTTRRMSLTPEGEVYLEHARRILSDI
DGLEQLIHGATTSARGLLRVNATPGFGRSHIAPLVSKFIFGHPGVEVQLQLSVNPPPLTEDSFDVCIRFGSPPDARVIAR
HIAPNRRLLCASPVYIAKHGLPEVPRDLTRHNCIGIRQGDEAYGVWRLTSGCGRFSTTEVVKTRGNLTTNDGEIAVNWAL
DGHGILMRAEWDIERYLKSGRLVQVLPQCHTPDANIHAVYPKRHQNAGRVRAFVEFITRSLTPNLAP

Sequences:

>Translated_307_residues
MSGSGIQPADFGFFSTLATAGSLSAAARELGITTPAVSKHLASMESRMGVTLVNRTTRRMSLTPEGEVYLEHARRILSDI
DGLEQLIHGATTSARGLLRVNATPGFGRSHIAPLVSKFIFGHPGVEVQLQLSVNPPPLTEDSFDVCIRFGSPPDARVIAR
HIAPNRRLLCASPVYIAKHGLPEVPRDLTRHNCIGIRQGDEAYGVWRLTSGCGRFSTTEVVKTRGNLTTNDGEIAVNWAL
DGHGILMRAEWDIERYLKSGRLVQVLPQCHTPDANIHAVYPKRHQNAGRVRAFVEFITRSLTPNLAP
>Mature_306_residues
SGSGIQPADFGFFSTLATAGSLSAAARELGITTPAVSKHLASMESRMGVTLVNRTTRRMSLTPEGEVYLEHARRILSDID
GLEQLIHGATTSARGLLRVNATPGFGRSHIAPLVSKFIFGHPGVEVQLQLSVNPPPLTEDSFDVCIRFGSPPDARVIARH
IAPNRRLLCASPVYIAKHGLPEVPRDLTRHNCIGIRQGDEAYGVWRLTSGCGRFSTTEVVKTRGNLTTNDGEIAVNWALD
GHGILMRAEWDIERYLKSGRLVQVLPQCHTPDANIHAVYPKRHQNAGRVRAFVEFITRSLTPNLAP

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=36.4583333333333, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI87081978, Length=300, Percent_Identity=36.6666666666667, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI145693193, Length=285, Percent_Identity=33.3333333333333, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1786401, Length=290, Percent_Identity=31.3793103448276, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1789639, Length=288, Percent_Identity=27.0833333333333, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1787128, Length=293, Percent_Identity=27.9863481228669, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1787589, Length=295, Percent_Identity=29.4915254237288, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790011, Length=318, Percent_Identity=25.4716981132075, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786448, Length=251, Percent_Identity=26.6932270916335, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI157672245, Length=143, Percent_Identity=32.8671328671329, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789173, Length=289, Percent_Identity=24.2214532871972, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788706, Length=279, Percent_Identity=24.0143369175627, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33524; Mature: 33393

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSGIQPADFGFFSTLATAGSLSAAARELGITTPAVSKHLASMESRMGVTLVNRTTRRM
CCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEECCCCEE
SLTPEGEVYLEHARRILSDIDGLEQLIHGATTSARGLLRVNATPGFGRSHIAPLVSKFIF
ECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
GHPGVEVQLQLSVNPPPLTEDSFDVCIRFGSPPDARVIARHIAPNRRLLCASPVYIAKHG
CCCCCEEEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCCEEEEECCHHHHHCC
LPEVPRDLTRHNCIGIRQGDEAYGVWRLTSGCGRFSTTEVVKTRGNLTTNDGEIAVNWAL
CCCCHHHHHHCCEEEECCCCCCEEEEEEECCCCCCCHHHHHHHCCCEECCCCCEEEEEEE
DGHGILMRAEWDIERYLKSGRLVQVLPQCHTPDANIHAVYPKRHQNAGRVRAFVEFITRS
CCCEEEEEECCCHHHHHHCCCEEEECCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHH
LTPNLAP
CCCCCCC
>Mature Secondary Structure 
SGSGIQPADFGFFSTLATAGSLSAAARELGITTPAVSKHLASMESRMGVTLVNRTTRRM
CCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEECCCCEE
SLTPEGEVYLEHARRILSDIDGLEQLIHGATTSARGLLRVNATPGFGRSHIAPLVSKFIF
ECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
GHPGVEVQLQLSVNPPPLTEDSFDVCIRFGSPPDARVIARHIAPNRRLLCASPVYIAKHG
CCCCCEEEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCCEEEEECCHHHHHCC
LPEVPRDLTRHNCIGIRQGDEAYGVWRLTSGCGRFSTTEVVKTRGNLTTNDGEIAVNWAL
CCCCHHHHHHCCEEEECCCCCCEEEEEEECCCCCCCHHHHHHHCCCEECCCCCEEEEEEE
DGHGILMRAEWDIERYLKSGRLVQVLPQCHTPDANIHAVYPKRHQNAGRVRAFVEFITRS
CCCEEEEEECCCHHHHHHCCCEEEECCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHH
LTPNLAP
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]