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The map label for this gene is infC [H]

Identifier: 121610034

GI number: 121610034

Start: 3441560

End: 3442099

Strand: Direct

Name: infC [H]

Synonym: Veis_3090

Alternate gene names: 121610034

Gene position: 3441560-3442099 (Clockwise)

Preceding gene: 121610033

Following gene: 121610035

Centisome position: 61.82

GC content: 60.56

Gene sequence:

>540_bases
ATGGCCCCGGAGGTACGCCTGTCCGGGCCTGACAACGAACCGCTGGGCGTTGTGAGCCTGATCGAAGCCTTGCGCATGGC
CGGCGAGTTGGATGTGGATCTGGTGGAAATCGCCGCCACGGCGAATCCTCCGGTGTGTCGCCTGATGGACTATGGCAAGT
TCAAGTACCAGGAACAAAAACGGGCCGCCGAAGCCAAGGCCAAGCAGACGGTCATCGAGATCAAGGAAGTCAAGTTTCGT
CCGGGCACGGACGATGGCGACTACCACATCAAGATGCGCAACATCCGCCGTTTTCTGGCCGACGGCGACAAGTGCAAGAT
CACGCTGCGCTTTCGCGGTCGTGAGATCACGCACCAGGAGCTCGGTCTGGCATTGCTCAATCGCATTCGCGACGAGTTGG
CCGATGTCATCATCGTCGAGCAGTTTCCCAAACTCGAAGGGCGCCAGATGATCATGATGATCGCCCCGGGCAAGAAAAAG
CCCGTGGCCAAACCGGTGCCGGACCAAGCCCCGGTCGCCGGCACTGCGGCGGTGACTTGA

Upstream 100 bases:

>100_bases
TTTTTTGTAGCGTCTTGATTCAAGGAAGATAACCATCGCTACTGAATTTCGTGATCGTCGCCACCGCGAAGAGCGCAAGC
ACCGCTTGAACCGTGAAATC

Downstream 100 bases:

>100_bases
AAATTTGGGCACCGCGCCCGCAAAGGCGCGGTGCCCAATCAAAGTGGCTCGGGGCCAACAAGTTTGCAGATCGGTCTGCA
AACGCCTCGCGAGCACAACC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MAPEVRLSGPDNEPLGVVSLIEALRMAGELDVDLVEIAATANPPVCRLMDYGKFKYQEQKRAAEAKAKQTVIEIKEVKFR
PGTDDGDYHIKMRNIRRFLADGDKCKITLRFRGREITHQELGLALLNRIRDELADVIIVEQFPKLEGRQMIMMIAPGKKK
PVAKPVPDQAPVAGTAAVT

Sequences:

>Translated_179_residues
MAPEVRLSGPDNEPLGVVSLIEALRMAGELDVDLVEIAATANPPVCRLMDYGKFKYQEQKRAAEAKAKQTVIEIKEVKFR
PGTDDGDYHIKMRNIRRFLADGDKCKITLRFRGREITHQELGLALLNRIRDELADVIIVEQFPKLEGRQMIMMIAPGKKK
PVAKPVPDQAPVAGTAAVT
>Mature_178_residues
APEVRLSGPDNEPLGVVSLIEALRMAGELDVDLVEIAATANPPVCRLMDYGKFKYQEQKRAAEAKAKQTVIEIKEVKFRP
GTDDGDYHIKMRNIRRFLADGDKCKITLRFRGREITHQELGLALLNRIRDELADVIIVEQFPKLEGRQMIMMIAPGKKKP
VAKPVPDQAPVAGTAAVT

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=160, Percent_Identity=60.625, Blast_Score=193, Evalue=4e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 19933; Mature: 19801

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPEVRLSGPDNEPLGVVSLIEALRMAGELDVDLVEIAATANPPVCRLMDYGKFKYQEQK
CCCCEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCHHHHHHH
RAAEAKAKQTVIEIKEVKFRPGTDDGDYHIKMRNIRRFLADGDKCKITLRFRGREITHQE
HHHHHHHHHHHHHHHHEEECCCCCCCCEEEEHHHHHHHHCCCCEEEEEEEECCCCCCHHH
LGLALLNRIRDELADVIIVEQFPKLEGRQMIMMIAPGKKKPVAKPVPDQAPVAGTAAVT
HHHHHHHHHHHHHHHEEHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
APEVRLSGPDNEPLGVVSLIEALRMAGELDVDLVEIAATANPPVCRLMDYGKFKYQEQK
CCCEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCHHHHHHH
RAAEAKAKQTVIEIKEVKFRPGTDDGDYHIKMRNIRRFLADGDKCKITLRFRGREITHQE
HHHHHHHHHHHHHHHHEEECCCCCCCCEEEEHHHHHHHHCCCCEEEEEEEECCCCCCHHH
LGLALLNRIRDELADVIIVEQFPKLEGRQMIMMIAPGKKKPVAKPVPDQAPVAGTAAVT
HHHHHHHHHHHHHHHEEHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]