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The map label for this gene is can [H]

Identifier: 120613006

GI number: 120613006

Start: 4856643

End: 4857305

Strand: Reverse

Name: can [H]

Synonym: Aave_4370

Alternate gene names: 120613006

Gene position: 4857305-4856643 (Counterclockwise)

Preceding gene: 120613007

Following gene: 120613005

Centisome position: 90.74

GC content: 65.31

Gene sequence:

>663_bases
ATGACCGCTCCCAGTATCGATGAATTGTTCGTCCACAACCGCGCATGGGCCGCGCGGATGGAGCGGGAGCGTCCTGGCTT
TTTCACGGAGCTGATGGCGCAGCAGAAGCCCCGGTACATGTGGGTGGGCTGCTCGGACAGCCGGGTGCCGGCCAACCAGA
TCACGGGGCTGGAGCCGGGCGAGGTGTTCGTGCACCGGAACGTGGCGAATGTGGTCGTGCCCACGGACCTGAACTGCCTC
TCGACCATCCAGTACGCGGTGGACCAGTTGCAGGTGGAGCACCTGATGGTCGTGGGCCACTACGGCTGTGGTGGCGTTCG
CGCGGCGCTGGAGGGCGTTCGCGTGGGACTGGCCGACAACTGGATCCGCCATGTGAAGGATGTCCGAGACCGCCACAAGG
AGCTGATTGCCGCCACGCCGACGGACCTGCAGCTCGACGTGCTGTGCGAACTCAATGCCATCGAGCAGGTGGTGAACGTG
GCGCAGACGACCGTGATGGCCGATGCCTGGGGCCGGGGGCAGAAGGTGACGCTGCACGGCTGGTGCTATGGCCTCAAGGA
TGGGCTGATCAACAACCTCCACATGACGGTGTCGGGCATCCAGGGACTGGATTCCGTGTACAAGGCGGCGATCCAGGGCG
TGGCCAACCGCCTGCGGGGGTAG

Upstream 100 bases:

>100_bases
AGATCGGCGCCGGCACCAGCGAGATCCGCCGCATGCTGATCGGTCGGGAACTGTTCGCCGAGACCACCTGACTTTGTACA
ACGCTCCAGAAAGAAGCCTG

Downstream 100 bases:

>100_bases
GTCGCCACCACTTTCCGGCAACGTGTCGATGGAGCAAGCAGCCATGTTCCCACGGCGTCTCGATTCTCCTGCCGCCTACG
GCATCGCGCAGGCGATGATG

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MTAPSIDELFVHNRAWAARMERERPGFFTELMAQQKPRYMWVGCSDSRVPANQITGLEPGEVFVHRNVANVVVPTDLNCL
STIQYAVDQLQVEHLMVVGHYGCGGVRAALEGVRVGLADNWIRHVKDVRDRHKELIAATPTDLQLDVLCELNAIEQVVNV
AQTTVMADAWGRGQKVTLHGWCYGLKDGLINNLHMTVSGIQGLDSVYKAAIQGVANRLRG

Sequences:

>Translated_220_residues
MTAPSIDELFVHNRAWAARMERERPGFFTELMAQQKPRYMWVGCSDSRVPANQITGLEPGEVFVHRNVANVVVPTDLNCL
STIQYAVDQLQVEHLMVVGHYGCGGVRAALEGVRVGLADNWIRHVKDVRDRHKELIAATPTDLQLDVLCELNAIEQVVNV
AQTTVMADAWGRGQKVTLHGWCYGLKDGLINNLHMTVSGIQGLDSVYKAAIQGVANRLRG
>Mature_219_residues
TAPSIDELFVHNRAWAARMERERPGFFTELMAQQKPRYMWVGCSDSRVPANQITGLEPGEVFVHRNVANVVVPTDLNCLS
TIQYAVDQLQVEHLMVVGHYGCGGVRAALEGVRVGLADNWIRHVKDVRDRHKELIAATPTDLQLDVLCELNAIEQVVNVA
QTTVMADAWGRGQKVTLHGWCYGLKDGLINNLHMTVSGIQGLDSVYKAAIQGVANRLRG

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=209, Percent_Identity=53.11004784689, Blast_Score=256, Evalue=6e-70,
Organism=Escherichia coli, GI1786534, Length=176, Percent_Identity=29.5454545454545, Blast_Score=82, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324292, Length=195, Percent_Identity=27.6923076923077, Blast_Score=89, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 24369; Mature: 24238

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPSIDELFVHNRAWAARMERERPGFFTELMAQQKPRYMWVGCSDSRVPANQITGLEPG
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHCCCCCCC
EVFVHRNVANVVVPTDLNCLSTIQYAVDQLQVEHLMVVGHYGCGGVRAALEGVRVGLADN
CEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHCHHHH
WIRHVKDVRDRHKELIAATPTDLQLDVLCELNAIEQVVNVAQTTVMADAWGRGQKVTLHG
HHHHHHHHHHHHHHHEECCCCCCEEEHEECHHHHHHHHHHHHHHHHHHCCCCCCEEEEEH
WCYGLKDGLINNLHMTVSGIQGLDSVYKAAIQGVANRLRG
EEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TAPSIDELFVHNRAWAARMERERPGFFTELMAQQKPRYMWVGCSDSRVPANQITGLEPG
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHCCCCCCC
EVFVHRNVANVVVPTDLNCLSTIQYAVDQLQVEHLMVVGHYGCGGVRAALEGVRVGLADN
CEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHCHHHH
WIRHVKDVRDRHKELIAATPTDLQLDVLCELNAIEQVVNVAQTTVMADAWGRGQKVTLHG
HHHHHHHHHHHHHHHEECCCCCCEEEHEECHHHHHHHHHHHHHHHHHHCCCCCCEEEEEH
WCYGLKDGLINNLHMTVSGIQGLDSVYKAAIQGVANRLRG
EEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]