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The map label for this gene is yfdE [H]

Identifier: 120612946

GI number: 120612946

Start: 4786456

End: 4787730

Strand: Reverse

Name: yfdE [H]

Synonym: Aave_4310

Alternate gene names: 120612946

Gene position: 4787730-4786456 (Counterclockwise)

Preceding gene: 120612947

Following gene: 120612945

Centisome position: 89.44

GC content: 69.65

Gene sequence:

>1275_bases
ATGACTGGAGACAAGACATTGAATGCCACCACTTCCGCCGCCGCGCCTGACGCCATCGACTTTCCGCTGGAGGGCGTGCG
CGTGCTCGATCTCTCGCGCGTGTTCGCCGGGCCGCTGTGCGGCCAGGTGCTGGCAGACTTCGGCGCCGAGGTGGTGAAGG
TGGAGCACCCCGGCCGCGGCGACGACACGCGCGACTGGGGCATGCGCATCGGCAGGACCGAGACCACCTACTACAACAGC
ATGAACCGCAACAAGCGGTCGATCACGCTGGACCTGCAGAGCCCCGAGGGCGCGAGGATCGTGCACGAGCTGCTGCCGCA
GTTCGACGTGGTGATCCACAACTTCAAGACCGGCGGTGCCGAGAAGCTGGGCCTGGGCTACGAGCAGCTCAAGGCGATCA
GGCCCGACCTGATCTACTGCGCCGTGGCCGGCTACGACGTGACCGGCCCCGAGGCGAAGCGGCCGGGCTACGACCTGGTG
ATCCAGGGCGAGACGGGCCTCATGGCGCTCAACGGCGAGGCCTCGCAGCCGCCGCTGAAATTCGGCGTGGCCGTGGTGGA
CCTGATGACCGGCATGTACGCCGCGCAGGCCGTGCTGGCGGCGCTCTTCCAGCGCAGCCGCACCGGCCGGGGCCGGTTGA
TCGAGATGGCGCTCTACGACTGCGGCCTCATGGTCACCGGCTACTACGGGCTCGACGCGATGCAGCTGGGGCGCGATCCG
GCGCGCTACGGCAACGCCCACCCCTCCATCGTGCCCTACGGCATGTTCGAGGCGGCCGATGGCCCGCTCATCATCGCCGT
GGGCAACAACGCCCAGTTCGACAAGTTCTGCCGCCAGGTGATCGAGCGGCCCGACATCGTGGAAGACCCGCGTTTCGCCA
CCAACGTGCAGCGCGCGAAGAACCGCCACGAGATCGGCCCGATGCTCACGGAACTGATCCGCGCCTTCCCGCGCGACGTG
CTGCTCGAACGCATGACCGCCTGCGGCATTCCCTGCGGCAAGGTGGCGGGCCTGCACGAGGCGCTCACCAGCGAGCGCAC
GCGGCGCGGCGGCCTCCTGCAGGACATGCCGCACCCCGTGGCGGGAACCACGCCGGTGTTCGCGCCGCCCTACCGTATCG
ACGGCCAGCGCCTGCCCATCCGCCATGCGCCGCCCACGCTGGGCGAGGGCACGCGCGAAGTGCTGCAGCGCCTGCTGCAA
CTGAGCGACGAGCAACTGCAGGGCCTGCAGCAGCGCGGCGTGCTGACGCTGCCGGAGGCACCCCCGCCAGTCTGA

Upstream 100 bases:

>100_bases
CGATTACGTGCGCCTGCGCGGCCCGGCGGGCTGACGCGCTCCCGGTGCCGGGTCGCGAAGGGGGCAGCGGCCACGCCGCC
CGCCGCATCACAATGAACGA

Downstream 100 bases:

>100_bases
TTTTCCCCGCCGGCCCGTTGCACCAGGCCGCCCGCAGAGGCGGCGCACCGGAGCCGATCTTCCCCAGAGAACCCCCGGAG
ACAACACCATGACAGGTTCC

Product: L-carnitine dehydratase/bile acid-inducible protein F

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MTGDKTLNATTSAAAPDAIDFPLEGVRVLDLSRVFAGPLCGQVLADFGAEVVKVEHPGRGDDTRDWGMRIGRTETTYYNS
MNRNKRSITLDLQSPEGARIVHELLPQFDVVIHNFKTGGAEKLGLGYEQLKAIRPDLIYCAVAGYDVTGPEAKRPGYDLV
IQGETGLMALNGEASQPPLKFGVAVVDLMTGMYAAQAVLAALFQRSRTGRGRLIEMALYDCGLMVTGYYGLDAMQLGRDP
ARYGNAHPSIVPYGMFEAADGPLIIAVGNNAQFDKFCRQVIERPDIVEDPRFATNVQRAKNRHEIGPMLTELIRAFPRDV
LLERMTACGIPCGKVAGLHEALTSERTRRGGLLQDMPHPVAGTTPVFAPPYRIDGQRLPIRHAPPTLGEGTREVLQRLLQ
LSDEQLQGLQQRGVLTLPEAPPPV

Sequences:

>Translated_424_residues
MTGDKTLNATTSAAAPDAIDFPLEGVRVLDLSRVFAGPLCGQVLADFGAEVVKVEHPGRGDDTRDWGMRIGRTETTYYNS
MNRNKRSITLDLQSPEGARIVHELLPQFDVVIHNFKTGGAEKLGLGYEQLKAIRPDLIYCAVAGYDVTGPEAKRPGYDLV
IQGETGLMALNGEASQPPLKFGVAVVDLMTGMYAAQAVLAALFQRSRTGRGRLIEMALYDCGLMVTGYYGLDAMQLGRDP
ARYGNAHPSIVPYGMFEAADGPLIIAVGNNAQFDKFCRQVIERPDIVEDPRFATNVQRAKNRHEIGPMLTELIRAFPRDV
LLERMTACGIPCGKVAGLHEALTSERTRRGGLLQDMPHPVAGTTPVFAPPYRIDGQRLPIRHAPPTLGEGTREVLQRLLQ
LSDEQLQGLQQRGVLTLPEAPPPV
>Mature_423_residues
TGDKTLNATTSAAAPDAIDFPLEGVRVLDLSRVFAGPLCGQVLADFGAEVVKVEHPGRGDDTRDWGMRIGRTETTYYNSM
NRNKRSITLDLQSPEGARIVHELLPQFDVVIHNFKTGGAEKLGLGYEQLKAIRPDLIYCAVAGYDVTGPEAKRPGYDLVI
QGETGLMALNGEASQPPLKFGVAVVDLMTGMYAAQAVLAALFQRSRTGRGRLIEMALYDCGLMVTGYYGLDAMQLGRDPA
RYGNAHPSIVPYGMFEAADGPLIIAVGNNAQFDKFCRQVIERPDIVEDPRFATNVQRAKNRHEIGPMLTELIRAFPRDVL
LERMTACGIPCGKVAGLHEALTSERTRRGGLLQDMPHPVAGTTPVFAPPYRIDGQRLPIRHAPPTLGEGTREVLQRLLQL
SDEQLQGLQQRGVLTLPEAPPPV

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=394, Percent_Identity=37.0558375634518, Blast_Score=293, Evalue=3e-79,
Organism=Homo sapiens, GI300863124, Length=420, Percent_Identity=35.2380952380952, Blast_Score=282, Evalue=3e-76,
Organism=Homo sapiens, GI13376042, Length=420, Percent_Identity=32.1428571428571, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI300863126, Length=395, Percent_Identity=33.4177215189873, Blast_Score=235, Evalue=5e-62,
Organism=Homo sapiens, GI42794625, Length=254, Percent_Identity=30.3149606299213, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI266456254, Length=254, Percent_Identity=30.3149606299213, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI266458393, Length=258, Percent_Identity=30.2325581395349, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI266458397, Length=274, Percent_Identity=29.5620437956204, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI42822893, Length=137, Percent_Identity=37.2262773722628, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI266458395, Length=137, Percent_Identity=37.2262773722628, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI87082093, Length=332, Percent_Identity=34.0361445783133, Blast_Score=228, Evalue=7e-61,
Organism=Escherichia coli, GI1788717, Length=416, Percent_Identity=28.125, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1786222, Length=325, Percent_Identity=26.4615384615385, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32564160, Length=199, Percent_Identity=27.6381909547739, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115535051, Length=189, Percent_Identity=27.5132275132275, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24648431, Length=416, Percent_Identity=39.1826923076923, Blast_Score=293, Evalue=1e-79,
Organism=Drosophila melanogaster, GI24585488, Length=410, Percent_Identity=23.9024390243902, Blast_Score=105, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 46251; Mature: 46120

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGDKTLNATTSAAAPDAIDFPLEGVRVLDLSRVFAGPLCGQVLADFGAEVVKVEHPGRG
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
DDTRDWGMRIGRTETTYYNSMNRNKRSITLDLQSPEGARIVHELLPQFDVVIHNFKTGGA
CCCHHHCCCCCCCCHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCC
EKLGLGYEQLKAIRPDLIYCAVAGYDVTGPEAKRPGYDLVIQGETGLMALNGEASQPPLK
HHHCCCHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCCCHH
FGVAVVDLMTGMYAAQAVLAALFQRSRTGRGRLIEMALYDCGLMVTGYYGLDAMQLGRDP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHCCEEEEECCCCCHHHHCCCH
ARYGNAHPSIVPYGMFEAADGPLIIAVGNNAQFDKFCRQVIERPDIVEDPRFATNVQRAK
HHCCCCCCCEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHH
NRHEIGPMLTELIRAFPRDVLLERMTACGIPCGKVAGLHEALTSERTRRGGLLQDMPHPV
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCC
AGTTPVFAPPYRIDGQRLPIRHAPPTLGEGTREVLQRLLQLSDEQLQGLQQRGVLTLPEA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCEECCCC
PPPV
CCCC
>Mature Secondary Structure 
TGDKTLNATTSAAAPDAIDFPLEGVRVLDLSRVFAGPLCGQVLADFGAEVVKVEHPGRG
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
DDTRDWGMRIGRTETTYYNSMNRNKRSITLDLQSPEGARIVHELLPQFDVVIHNFKTGGA
CCCHHHCCCCCCCCHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCC
EKLGLGYEQLKAIRPDLIYCAVAGYDVTGPEAKRPGYDLVIQGETGLMALNGEASQPPLK
HHHCCCHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCCCHH
FGVAVVDLMTGMYAAQAVLAALFQRSRTGRGRLIEMALYDCGLMVTGYYGLDAMQLGRDP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHCCEEEEECCCCCHHHHCCCH
ARYGNAHPSIVPYGMFEAADGPLIIAVGNNAQFDKFCRQVIERPDIVEDPRFATNVQRAK
HHCCCCCCCEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHH
NRHEIGPMLTELIRAFPRDVLLERMTACGIPCGKVAGLHEALTSERTRRGGLLQDMPHPV
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCC
AGTTPVFAPPYRIDGQRLPIRHAPPTLGEGTREVLQRLLQLSDEQLQGLQQRGVLTLPEA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCEECCCC
PPPV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]