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The map label for this gene is tcp [H]

Identifier: 120612939

GI number: 120612939

Start: 4778732

End: 4780318

Strand: Reverse

Name: tcp [H]

Synonym: Aave_4303

Alternate gene names: 120612939

Gene position: 4780318-4778732 (Counterclockwise)

Preceding gene: 120612940

Following gene: 120612938

Centisome position: 89.31

GC content: 72.09

Gene sequence:

>1587_bases
ATGAACCTGAACAATGCCCGTTTGTCGCTGCGCCTGGCCCTGGCCTTCGGCGCCGTTTGTTTCGTCATGTCGCTGGCCGC
GGGAGTCGGCATCTGGCGGCTGATGAACCTGCAGGACATCGCGGACGACCTGGGGGGCGCGTCCGCCGAGCGGGCGCTGC
TCGCCCGCGAACTCCATTCCATCGTGGTCCTGAGTTCCGCGCGCGCCGAGGCGCTGCTGGAAGTCGGCAGCCCCGAATAC
ACGGCCCGCGTGGAAGCGGACCGCAAGCTGACTTCGGCGCGTTCCTCCGAGGTGCGCAAGCGGCTGGAAACCCTGGCCGA
GGACACGGAGTCCCAGCGCATCTTCCGCGACATCGACACCGCGGGCAATGGCTTCCGGGCCGCCCGGGACGATCTCGTCA
AGCGCCGCAGGGCCGGCGAGACGCTGCCGCCCGATGCCGTGGGCAAGCTGCTGCGGCCCGCCGCCGACCGCTATGCCGCC
GCCGTGGAGGAAATGGCCGACTACCAGCGCAAGCGCGTGGCCGAGGCCCGTGAGCGTGCCGAGGCGAGCGAGCGGCAAGG
CATCGCGCTGCTCGTGGGCGGCTCGCTGGTGGGCCTGCTCCTGAGCCTGGGCTGCGCGCTGCTGCTCTCGCGCTCCATCC
TCGTGCCGCTGGCGCAGGCCTCTTCCGTGTCCGACCGCATCGCCGAGGGCGATCTGACGTCTTCCGTGCCGGCGGCCGGC
GCCGGCAACCGCGACGAAGTGCGCGCCCTGCTGGAGCGCCTGGGCGGCATGCAGCAGCGGCTCGCCGGGCTGGTGGTGGG
CATGCGGCAGGCCAGTGCTTCCGTGGCAGGCGCCAGCGCGGAGATCGCCGCCGGGAACACCGATCTGTCATCGCGCACCG
AGCACACGGCCTCCAACCTGGAGGAGATCGCCGCCAGCATGGAGGAGCTCATCGCCACCGTGCGCCACAGCGCGGATGCG
GCGCAGCAGGCGAGCGCCCTGGCGGCCTCGGCCAGCGACGTGGCGCGGCGCGGTCGGGATGCCGTCAACCAGGTGGTCTC
CACCATGGACGGCATCGCGCAGGCATCCCGCAAGATCGCCGACATCACCAGCGTGATCGACGGCATCGCCTTCCAGACCA
ACATCCTCGCCCTCAACGCGGCGGTGGAGGCTGCCCGCGCGGGCGAGCAGGGCAGGGGGTTCGCCGTGGTCGCATCGGAG
GTGCGCAGCCTCGCGCAGCGTTCGGCCACGGCCGCCCGGGAGATCGGCGCCCTCATCGGCGACAGCGTGCGTCAGGTGGG
CGAAGGTGCCCAGCAGGTCCATGCCGCAGGCGGCACCATGGGCGAGATCGTGGGCTCGGTGGAGCAGGTCGCGACCATCA
TCGGCGAGATCAGCACGGCCGCGCGCGAGCAGAGCACCGGCCTGGGGCAGGTCGGCGAGGCGGTGAGCCAGCTCGACCAG
ATGACCCAGCAGAACGCCGCCCTGGTGGAGGAATCCACCGCCGCGGCCCAGAGCCTGCGCATGCAGGCGCAGCAACTGGC
CGACCTGGTGGCGGCATTCCGGCTTCCGGAAGGCGGGCACGGCCAGGCACCCGCGCTGCCGCGGTGA

Upstream 100 bases:

>100_bases
CCTGGCGGAGTCGGTGAATAATGCGGCGATCGGCCGTTGAACTCGACCGTACGGCCGGTACCGGCCTTTTTCGCAACCGT
CCGAACGGACCGCCGACGCC

Downstream 100 bases:

>100_bases
AGGATCACCGGGCCGGGCTCGTTCCATCTTTCCTTTTCTTTACACGCTGGTTGTCGGCGGACGGGATACGGCCGCGTTCA
AGGAGCATGTCTTTCCCATT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MNLNNARLSLRLALAFGAVCFVMSLAAGVGIWRLMNLQDIADDLGGASAERALLARELHSIVVLSSARAEALLEVGSPEY
TARVEADRKLTSARSSEVRKRLETLAEDTESQRIFRDIDTAGNGFRAARDDLVKRRRAGETLPPDAVGKLLRPAADRYAA
AVEEMADYQRKRVAEARERAEASERQGIALLVGGSLVGLLLSLGCALLLSRSILVPLAQASSVSDRIAEGDLTSSVPAAG
AGNRDEVRALLERLGGMQQRLAGLVVGMRQASASVAGASAEIAAGNTDLSSRTEHTASNLEEIAASMEELIATVRHSADA
AQQASALAASASDVARRGRDAVNQVVSTMDGIAQASRKIADITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASE
VRSLAQRSATAAREIGALIGDSVRQVGEGAQQVHAAGGTMGEIVGSVEQVATIIGEISTAAREQSTGLGQVGEAVSQLDQ
MTQQNAALVEESTAAAQSLRMQAQQLADLVAAFRLPEGGHGQAPALPR

Sequences:

>Translated_528_residues
MNLNNARLSLRLALAFGAVCFVMSLAAGVGIWRLMNLQDIADDLGGASAERALLARELHSIVVLSSARAEALLEVGSPEY
TARVEADRKLTSARSSEVRKRLETLAEDTESQRIFRDIDTAGNGFRAARDDLVKRRRAGETLPPDAVGKLLRPAADRYAA
AVEEMADYQRKRVAEARERAEASERQGIALLVGGSLVGLLLSLGCALLLSRSILVPLAQASSVSDRIAEGDLTSSVPAAG
AGNRDEVRALLERLGGMQQRLAGLVVGMRQASASVAGASAEIAAGNTDLSSRTEHTASNLEEIAASMEELIATVRHSADA
AQQASALAASASDVARRGRDAVNQVVSTMDGIAQASRKIADITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASE
VRSLAQRSATAAREIGALIGDSVRQVGEGAQQVHAAGGTMGEIVGSVEQVATIIGEISTAAREQSTGLGQVGEAVSQLDQ
MTQQNAALVEESTAAAQSLRMQAQQLADLVAAFRLPEGGHGQAPALPR
>Mature_528_residues
MNLNNARLSLRLALAFGAVCFVMSLAAGVGIWRLMNLQDIADDLGGASAERALLARELHSIVVLSSARAEALLEVGSPEY
TARVEADRKLTSARSSEVRKRLETLAEDTESQRIFRDIDTAGNGFRAARDDLVKRRRAGETLPPDAVGKLLRPAADRYAA
AVEEMADYQRKRVAEARERAEASERQGIALLVGGSLVGLLLSLGCALLLSRSILVPLAQASSVSDRIAEGDLTSSVPAAG
AGNRDEVRALLERLGGMQQRLAGLVVGMRQASASVAGASAEIAAGNTDLSSRTEHTASNLEEIAASMEELIATVRHSADA
AQQASALAASASDVARRGRDAVNQVVSTMDGIAQASRKIADITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASE
VRSLAQRSATAAREIGALIGDSVRQVGEGAQQVHAAGGTMGEIVGSVEQVATIIGEISTAAREQSTGLGQVGEAVSQLDQ
MTQQNAALVEESTAAAQSLRMQAQQLADLVAAFRLPEGGHGQAPALPR

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=366, Percent_Identity=47.8142076502732, Blast_Score=285, Evalue=7e-78,
Organism=Escherichia coli, GI1788195, Length=481, Percent_Identity=43.4511434511435, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1788194, Length=330, Percent_Identity=51.5151515151515, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI2367378, Length=354, Percent_Identity=51.4124293785311, Blast_Score=269, Evalue=3e-73,
Organism=Escherichia coli, GI1789453, Length=332, Percent_Identity=38.855421686747, Blast_Score=202, Evalue=4e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 54976; Mature: 54976

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLNNARLSLRLALAFGAVCFVMSLAAGVGIWRLMNLQDIADDLGGASAERALLARELHS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IVVLSSARAEALLEVGSPEYTARVEADRKLTSARSSEVRKRLETLAEDTESQRIFRDIDT
HHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AGNGFRAARDDLVKRRRAGETLPPDAVGKLLRPAADRYAAAVEEMADYQRKRVAEARERA
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EASERQGIALLVGGSLVGLLLSLGCALLLSRSILVPLAQASSVSDRIAEGDLTSSVPAAG
HHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
AGNRDEVRALLERLGGMQQRLAGLVVGMRQASASVAGASAEIAAGNTDLSSRTEHTASNL
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHH
EEIAASMEELIATVRHSADAAQQASALAASASDVARRGRDAVNQVVSTMDGIAQASRKIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRSLAQRSATAAREIGALIG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSVRQVGEGAQQVHAAGGTMGEIVGSVEQVATIIGEISTAAREQSTGLGQVGEAVSQLDQ
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
MTQQNAALVEESTAAAQSLRMQAQQLADLVAAFRLPEGGHGQAPALPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNLNNARLSLRLALAFGAVCFVMSLAAGVGIWRLMNLQDIADDLGGASAERALLARELHS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IVVLSSARAEALLEVGSPEYTARVEADRKLTSARSSEVRKRLETLAEDTESQRIFRDIDT
HHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AGNGFRAARDDLVKRRRAGETLPPDAVGKLLRPAADRYAAAVEEMADYQRKRVAEARERA
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EASERQGIALLVGGSLVGLLLSLGCALLLSRSILVPLAQASSVSDRIAEGDLTSSVPAAG
HHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
AGNRDEVRALLERLGGMQQRLAGLVVGMRQASASVAGASAEIAAGNTDLSSRTEHTASNL
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHH
EEIAASMEELIATVRHSADAAQQASALAASASDVARRGRDAVNQVVSTMDGIAQASRKIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRSLAQRSATAAREIGALIG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSVRQVGEGAQQVHAAGGTMGEIVGSVEQVATIIGEISTAAREQSTGLGQVGEAVSQLDQ
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
MTQQNAALVEESTAAAQSLRMQAQQLADLVAAFRLPEGGHGQAPALPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]