Click here to switch to the map view.

The map label for this gene is 120612870

Identifier: 120612870

GI number: 120612870

Start: 4690596

End: 4691774

Strand: Direct

Name: 120612870

Synonym: Aave_4234

Alternate gene names: NA

Gene position: 4690596-4691774 (Clockwise)

Preceding gene: 120612869

Following gene: 120612877

Centisome position: 87.63

GC content: 74.05

Gene sequence:

>1179_bases
ATGAAAACCATGCCTGACGCCGCCGCCGCACTGCACGCCACCATCGGCCAGCGGGTGGACCTGATCGACACCCCCGCCGC
GGTCGTGGACCTCGACGCCATGGAGCGCAACATCCAGCGCATGGCCGAGTTCGCGCGCAAGCACCAGGTACGCTGGCGCC
CGCACGCGAAGATGCACAAGTGCGCCGAACTGGCGCTGCGCCTGCAGCAGGCCGGTGCCGGCGGCGCCTGCGTGCAGAAG
GTCTCGGAGGCCGAGGCGCTCGCCGCCGGCGGCGTGACGGACATCTACATCAGCAACGAGGTGATCGCGCCGGCCAAGCT
GCTGCGCGTGGCGCGCCTGGCACGGCAGCTCGCCGGCATGGGCGGGCGCCTCGCGATCGCCGTGGACAGCCTGGAAGGCA
TCGGCCGCCTGGCCGAAGCCATGGAGGGTGCGGGCGCGGATGCCGGCATCGACGTGTTCGTGGAGATCGACGTCGGCCAG
GGCCGCTGCGGCGTGCCGCCGGGCGGGGCGGCCGTGCCGCTCGCGCAGGCGGTCGCCGGCCATGCCCGGCTGCGCTTCGC
CGGCCTGCATGCCTACCATGGCCAGGCCCAGCACCTGCGCGGCGCGGCCGAACGGCGCGACGCGGTCGCCGCAGCGGTGG
AGGCGGCCCGCGCCACGCGCGATGCCATCCAGGCGGCGGGCCTGCCCGTCCCCCTCGTCACCGGCGCGGGCACGGGCACC
CTGGTGCACGAGGCCGCGAGCGGCGTGTACGGCGAGCTGCAGGCCGGCTCCTTCCTGTTCATGGACGCGGACTACGCGGC
CAACGAGCGCGAGCCCGCGCAGCCGGCTTTCGAGCATGCGCTGTTCATCAAGACCCAGGTCATCTCCAGCCGCGACACGC
ACGCCGTCTGCGATGCGGGCCACAAGAGCCACGCCATCGATTCGGGGCTGCCGCAGGTCGCCTTCCTGCCGCCCGAACGT
GCGCTGCGCTACGCCAACGGCGGCGACGAGCACGGCCTGCTGTTCGCGGACAGCCTCCGTGCCCGGCTGCCCGCCATCGG
CCGCATGCTCTGGCTCATCCCCGGCCACTGCGACCCGACGGTGAACCTCCACGGCCACCTCATCGGCGTGCGGGGCGGGC
TCGCGCACGGCGTGGTCGAGCGCATCCTGCGCGTGGACGCCCGGGGCGCGGTGACCTGA

Upstream 100 bases:

>100_bases
CTCCTGGCCAACGCCGCCATCAACCGGCTGCTCTGGACCGAAGACGGACTCACCCTGGTGGGCTGGGCCGACACGCAGCA
CCTCGAGGACGCCGCCCGCG

Downstream 100 bases:

>100_bases
GGGCGGGCTCAGTCGGGCCGGGGCGGAAACAGCCCCTGCACGCAGATGATGAAGGCCACCGTCAGCGACGGCTGGAGCGT
GCCCACCGTCCCGGACGCTG

Product: putative threonine aldolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MKTMPDAAAALHATIGQRVDLIDTPAAVVDLDAMERNIQRMAEFARKHQVRWRPHAKMHKCAELALRLQQAGAGGACVQK
VSEAEALAAGGVTDIYISNEVIAPAKLLRVARLARQLAGMGGRLAIAVDSLEGIGRLAEAMEGAGADAGIDVFVEIDVGQ
GRCGVPPGGAAVPLAQAVAGHARLRFAGLHAYHGQAQHLRGAAERRDAVAAAVEAARATRDAIQAAGLPVPLVTGAGTGT
LVHEAASGVYGELQAGSFLFMDADYAANEREPAQPAFEHALFIKTQVISSRDTHAVCDAGHKSHAIDSGLPQVAFLPPER
ALRYANGGDEHGLLFADSLRARLPAIGRMLWLIPGHCDPTVNLHGHLIGVRGGLAHGVVERILRVDARGAVT

Sequences:

>Translated_392_residues
MKTMPDAAAALHATIGQRVDLIDTPAAVVDLDAMERNIQRMAEFARKHQVRWRPHAKMHKCAELALRLQQAGAGGACVQK
VSEAEALAAGGVTDIYISNEVIAPAKLLRVARLARQLAGMGGRLAIAVDSLEGIGRLAEAMEGAGADAGIDVFVEIDVGQ
GRCGVPPGGAAVPLAQAVAGHARLRFAGLHAYHGQAQHLRGAAERRDAVAAAVEAARATRDAIQAAGLPVPLVTGAGTGT
LVHEAASGVYGELQAGSFLFMDADYAANEREPAQPAFEHALFIKTQVISSRDTHAVCDAGHKSHAIDSGLPQVAFLPPER
ALRYANGGDEHGLLFADSLRARLPAIGRMLWLIPGHCDPTVNLHGHLIGVRGGLAHGVVERILRVDARGAVT
>Mature_392_residues
MKTMPDAAAALHATIGQRVDLIDTPAAVVDLDAMERNIQRMAEFARKHQVRWRPHAKMHKCAELALRLQQAGAGGACVQK
VSEAEALAAGGVTDIYISNEVIAPAKLLRVARLARQLAGMGGRLAIAVDSLEGIGRLAEAMEGAGADAGIDVFVEIDVGQ
GRCGVPPGGAAVPLAQAVAGHARLRFAGLHAYHGQAQHLRGAAERRDAVAAAVEAARATRDAIQAAGLPVPLVTGAGTGT
LVHEAASGVYGELQAGSFLFMDADYAANEREPAQPAFEHALFIKTQVISSRDTHAVCDAGHKSHAIDSGLPQVAFLPPER
ALRYANGGDEHGLLFADSLRARLPAIGRMLWLIPGHCDPTVNLHGHLIGVRGGLAHGVVERILRVDARGAVT

Specific function: Catalyzes the reversible cleavage of D-theronine or D- allothreonine into glycine and acetaldehyde. Can also cleave D- beta-phenylserine, D-beta-hydroxy-alpha-aminovaleric acid, D-beta- 3,4-dihydroxyphenylserine and D-beta-3,4- methylenedioxyphenylserine

COG id: COG3616

COG function: function code E; Predicted amino acid aldolase or racemase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DSD1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001608 [H]

Pfam domain/function: PF01168 Ala_racemase_N [H]

EC number: =4.1.2.42 [H]

Molecular weight: Translated: 40999; Mature: 40999

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTMPDAAAALHATIGQRVDLIDTPAAVVDLDAMERNIQRMAEFARKHQVRWRPHAKMHK
CCCCCHHHHHHHHHHCCCCCEECCCHHHEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
CAELALRLQQAGAGGACVQKVSEAEALAAGGVTDIYISNEVIAPAKLLRVARLARQLAGM
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCC
GGRLAIAVDSLEGIGRLAEAMEGAGADAGIDVFVEIDVGQGRCGVPPGGAAVPLAQAVAG
CCEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHH
HARLRFAGLHAYHGQAQHLRGAAERRDAVAAAVEAARATRDAIQAAGLPVPLVTGAGTGT
HHHEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCH
LVHEAASGVYGELQAGSFLFMDADYAANEREPAQPAFEHALFIKTQVISSRDTHAVCDAG
HHHHHHCCCCEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCC
HKSHAIDSGLPQVAFLPPERALRYANGGDEHGLLFADSLRARLPAIGRMLWLIPGHCDPT
CCCCCCCCCCCCEEECCHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHEEEEECCCCCCC
VNLHGHLIGVRGGLAHGVVERILRVDARGAVT
EEECEEEEEECCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKTMPDAAAALHATIGQRVDLIDTPAAVVDLDAMERNIQRMAEFARKHQVRWRPHAKMHK
CCCCCHHHHHHHHHHCCCCCEECCCHHHEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
CAELALRLQQAGAGGACVQKVSEAEALAAGGVTDIYISNEVIAPAKLLRVARLARQLAGM
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCC
GGRLAIAVDSLEGIGRLAEAMEGAGADAGIDVFVEIDVGQGRCGVPPGGAAVPLAQAVAG
CCEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHH
HARLRFAGLHAYHGQAQHLRGAAERRDAVAAAVEAARATRDAIQAAGLPVPLVTGAGTGT
HHHEEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCH
LVHEAASGVYGELQAGSFLFMDADYAANEREPAQPAFEHALFIKTQVISSRDTHAVCDAG
HHHHHHCCCCEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCC
HKSHAIDSGLPQVAFLPPERALRYANGGDEHGLLFADSLRARLPAIGRMLWLIPGHCDPT
CCCCCCCCCCCCEEECCHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHEEEEECCCCCCC
VNLHGHLIGVRGGLAHGVVERILRVDARGAVT
EEECEEEEEECCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9642221 [H]