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The map label for this gene is 120612862

Identifier: 120612862

GI number: 120612862

Start: 4683103

End: 4683480

Strand: Direct

Name: 120612862

Synonym: Aave_4226

Alternate gene names: NA

Gene position: 4683103-4683480 (Clockwise)

Preceding gene: 120612861

Following gene: 120612867

Centisome position: 87.49

GC content: 65.08

Gene sequence:

>378_bases
ATGCCCATGCACCCCGACGGCGGCCTCCAGATCCTCACGCTCACCGGTTTGCGCTTCGATGCCAACCTGGGCATCCTCGA
CCACGAGAAGACCGCGCCCCAGCCCATCCAGGTGGATGCGGAGCTCAACCAGGGCCGCCAGCCGCTGCTGCCGCACGACG
ACGACATCGGCCACGTGCTGGACTACCGCAAGGTGCGCCAGATCATCATCGACGAATGCACGGCCGAGCACGTGAACCTG
CTGGAGAGCCTGATCGGCAAGCTCACGCGCCGGCTGATGCAGCTGCCCGGCGTGCTCGGCGTGCGCGTGAAGATCGCCAA
GCTCGAAATCTTCGACGACTGCGAGGTGGCGATAAGGATGGAATGCGGGGAATGGTGA

Upstream 100 bases:

>100_bases
GGGCAGCACCTGATGCGCTTCGAGCGCGACTTCTCGCTCATGTGAGGCGCGGCGCGCAGGCCCCGCACCCATCCCCTTCA
TCGCTTTTTCTTCTGCCACC

Downstream 100 bases:

>100_bases
ACCCGGCGGCCTGACCTTCAGCAGCAGCGGCCGATGCGCCCGTTGCCGCCGTAGCGCGCGTCCTGCCGCTCCCGGAAGAA
CTCGGCATAGCTCATGACCG

Product: dihydroneopterin aldolase

Products: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine; glycolaldehyde

Alternate protein names: NA

Number of amino acids: Translated: 125; Mature: 124

Protein sequence:

>125_residues
MPMHPDGGLQILTLTGLRFDANLGILDHEKTAPQPIQVDAELNQGRQPLLPHDDDIGHVLDYRKVRQIIIDECTAEHVNL
LESLIGKLTRRLMQLPGVLGVRVKIAKLEIFDDCEVAIRMECGEW

Sequences:

>Translated_125_residues
MPMHPDGGLQILTLTGLRFDANLGILDHEKTAPQPIQVDAELNQGRQPLLPHDDDIGHVLDYRKVRQIIIDECTAEHVNL
LESLIGKLTRRLMQLPGVLGVRVKIAKLEIFDDCEVAIRMECGEW
>Mature_124_residues
PMHPDGGLQILTLTGLRFDANLGILDHEKTAPQPIQVDAELNQGRQPLLPHDDDIGHVLDYRKVRQIIIDECTAEHVNLL
ESLIGKLTRRLMQLPGVLGVRVKIAKLEIFDDCEVAIRMECGEW

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.1.2.25

Molecular weight: Translated: 14084; Mature: 13952

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMHPDGGLQILTLTGLRFDANLGILDHEKTAPQPIQVDAELNQGRQPLLPHDDDIGHVL
CCCCCCCCEEEEEEECEEEECCCCCEECCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHH
DYRKVRQIIIDECTAEHVNLLESLIGKLTRRLMQLPGVLGVRVKIAKLEIFDDCEVAIRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCEEEEE
ECGEW
ECCCC
>Mature Secondary Structure 
PMHPDGGLQILTLTGLRFDANLGILDHEKTAPQPIQVDAELNQGRQPLLPHDDDIGHVL
CCCCCCCEEEEEEECEEEECCCCCEECCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHH
DYRKVRQIIIDECTAEHVNLLESLIGKLTRRLMQLPGVLGVRVKIAKLEIFDDCEVAIRM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCEEEEE
ECGEW
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-; $dihydropteridine

Specific reaction: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8- $dihydropteridine = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA