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The map label for this gene is iorA [H]

Identifier: 120612565

GI number: 120612565

Start: 4351748

End: 4352290

Strand: Reverse

Name: iorA [H]

Synonym: Aave_3926

Alternate gene names: 120612565

Gene position: 4352290-4351748 (Counterclockwise)

Preceding gene: 120612566

Following gene: 120612564

Centisome position: 81.31

GC content: 71.64

Gene sequence:

>543_bases
ATGGGAAATCCCCTCCAATCCAGCAGCCCGGCCCCCGGCCTCCGGCTGCGGGTCAACGGCCGCGCCTGCGACGTGCCCGC
CGCACCCGGCACGGCACTGCTGCACGTGCTGCGCAATGACCTGGAGCTGAATGGCCCGAAGTACGGCTGCGGGCTGGGCG
AGTGCGGTGCCTGCACGGTGCTGATCGACGGCGTGGCCGCGCGCTCCTGCGTGATCCCCGTGCAGGCCGCCGTGGGCCGC
GAGGTGACCACGCTCGAAGGGCTCGGCTCGCGCGCATGCCCTGGCCCCACCCAGCAGGCCTTCATCGACTGCCAGGCGGC
CCAGTGCGGCTATTGCCTGAACGGCATGGTCATGACCGTCGAGGCCCTGCTGCGCCGCAATCCGCACCCGTCGGAGCAGG
AGGTTCGCAACGAACTGCACCACAACCTCTGCCGCTGCGGCACGCATGTGGAAATCCTGCAGGCCGCGCTGCGCGCCGCG
CAACTGCGTGCGGGCGGCGCGGGCGCGGATGGCTTGCCGACCGAAGCGGAAGTGCGCCCATGA

Upstream 100 bases:

>100_bases
TCCTGGTGCTTCGGCTACGACGTGTTCAGTATCCCCCTGGTGGAACCGAAGGTCGCCGCCGCGGCCTGATACTTCCCTGC
CGCAGCCGACAACGCATCCC

Downstream 100 bases:

>100_bases
ACCTGCCGGACCGTTCCATCACGCCTCTTGCGACCGAGGTTCCCGGCGCGCCCGCGGATCTGCTGCACGGGCTGGCCGTG
CGGCCCGGCCGCATGGGCTG

Product: 2Fe-2S iron-sulfur cluster-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MGNPLQSSSPAPGLRLRVNGRACDVPAAPGTALLHVLRNDLELNGPKYGCGLGECGACTVLIDGVAARSCVIPVQAAVGR
EVTTLEGLGSRACPGPTQQAFIDCQAAQCGYCLNGMVMTVEALLRRNPHPSEQEVRNELHHNLCRCGTHVEILQAALRAA
QLRAGGAGADGLPTEAEVRP

Sequences:

>Translated_180_residues
MGNPLQSSSPAPGLRLRVNGRACDVPAAPGTALLHVLRNDLELNGPKYGCGLGECGACTVLIDGVAARSCVIPVQAAVGR
EVTTLEGLGSRACPGPTQQAFIDCQAAQCGYCLNGMVMTVEALLRRNPHPSEQEVRNELHHNLCRCGTHVEILQAALRAA
QLRAGGAGADGLPTEAEVRP
>Mature_179_residues
GNPLQSSSPAPGLRLRVNGRACDVPAAPGTALLHVLRNDLELNGPKYGCGLGECGACTVLIDGVAARSCVIPVQAAVGRE
VTTLEGLGSRACPGPTQQAFIDCQAAQCGYCLNGMVMTVEALLRRNPHPSEQEVRNELHHNLCRCGTHVEILQAALRAAQ
LRAGGAGADGLPTEAEVRP

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=150, Percent_Identity=39.3333333333333, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI71773480, Length=90, Percent_Identity=40, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1786480, Length=172, Percent_Identity=37.2093023255814, Blast_Score=104, Evalue=3e-24,
Organism=Escherichia coli, GI1789232, Length=148, Percent_Identity=39.1891891891892, Blast_Score=92, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17540638, Length=160, Percent_Identity=40, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17539860, Length=157, Percent_Identity=36.3057324840764, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI32566215, Length=172, Percent_Identity=33.1395348837209, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17737937, Length=167, Percent_Identity=36.5269461077844, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24647193, Length=156, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24647199, Length=133, Percent_Identity=33.0827067669173, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24647197, Length=158, Percent_Identity=33.5443037974684, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24647195, Length=158, Percent_Identity=33.5443037974684, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24647201, Length=138, Percent_Identity=31.1594202898551, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 18726; Mature: 18594

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
6.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNPLQSSSPAPGLRLRVNGRACDVPAAPGTALLHVLRNDLELNGPKYGCGLGECGACTV
CCCCCCCCCCCCCEEEEECCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
LIDGVAARSCVIPVQAAVGREVTTLEGLGSRACPGPTQQAFIDCQAAQCGYCLNGMVMTV
EECCHHHHHHEEEHHHHHCCCHHHHHCCCCCCCCCCCHHHEEECCCCCCCHHHHHHHHHH
EALLRRNPHPSEQEVRNELHHNLCRCGTHVEILQAALRAAQLRAGGAGADGLPTEAEVRP
HHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GNPLQSSSPAPGLRLRVNGRACDVPAAPGTALLHVLRNDLELNGPKYGCGLGECGACTV
CCCCCCCCCCCCEEEEECCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
LIDGVAARSCVIPVQAAVGREVTTLEGLGSRACPGPTQQAFIDCQAAQCGYCLNGMVMTV
EECCHHHHHHEEEHHHHHCCCHHHHHCCCCCCCCCCCHHHEEECCCCCCCHHHHHHHHHH
EALLRRNPHPSEQEVRNELHHNLCRCGTHVEILQAALRAAQLRAGGAGADGLPTEAEVRP
HHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]