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The map label for this gene is nanR [H]

Identifier: 120612454

GI number: 120612454

Start: 4234869

End: 4235717

Strand: Reverse

Name: nanR [H]

Synonym: Aave_3813

Alternate gene names: 120612454

Gene position: 4235717-4234869 (Counterclockwise)

Preceding gene: 120612455

Following gene: 120612434

Centisome position: 79.13

GC content: 65.96

Gene sequence:

>849_bases
ATGGCGTCGGTGTCAAAGAAGCAGGTATCGCAGCGCGGCCCGAAACGTGGAGATCTGGTCGTCGAGGAGATCAAGCGCTG
GATCACCGACCGGAACCTCAGCCCCGGGGAAGGGCTTCCCAAGGAGGCCGAGTTGCAACAGCTGTTCGGGGTGGGCCGCG
GCACGATGCGCGAGGCCCTCAAGGCCCTGGAGGTGCAGGGCCTGATCCGGTTGACCACGGGGCCTTCCGGCGGCGCGGTG
ATAGAGCGCGTGACCTTCGACCGGACGTTCCAGTTCCTGCAGAACTATCTTTTCTTCGAGGACATCACCATCGGTGACAT
GTACGCCCTGCGTACGATCCTGGAGCCCGAGATGGCCGCCCTGGCGGTGCCCCACCTGGGCGAGAAGGAGTTCGACGCGC
TGGAGCGCAGCATCGCGATGTCGGACCCGCGCGAAGAGAACATCCAGCCTGCCGCGGTGCAGCGCATCGAGGACCTGCAC
TTCCACGACATCCTGGCCGATGCCTGCCCCAACCCCCTGCTGAGGTTCCAGTGCCGGCTCATCAACCGCATGCTGGAAAC
GATGGTGGTTTCCGCGCTGCACGCCACGCAGGAAGAACATCGCCGGCTCGGCGAGGCATCCTGGAAGGCGCATCGCCAGA
TACTCGCCGCTGCCCGCGACGCGGATGTATCGCAGGTGCGCAAGCTCATGCTGGCGCACATTGTCGAGAACCAGCGGCAT
CTGGATCTCCTGCAGTCCGGATTGCGCCGCCGGCTGGTGCTGGATTCCGACCTGCGCCTGGGTGGAGCACCTCTGCCGCA
GGTCCGGCCGATGCGGGCGCCTGCGCCCCGGACGAGAAAAGGCGCCTGA

Upstream 100 bases:

>100_bases
GCGCCCGCATTCCCCCTGGCGCCGCCTGCCGGGAGATGCGTGGCGCACGCGGCGGCGACGGTCGCGTGCGCTATCATCCG
GCGCAACAAAACAGCGGGGA

Downstream 100 bases:

>100_bases
CGGCGCCCGCGCTGTTCAGAAGACTGCGGTTTCGTCCGCGGCGGCAGCTTGCCGCTGCTGCAATCGCGCCACCATGAGCC
GCTGCATGTCGCCGGTACCC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MASVSKKQVSQRGPKRGDLVVEEIKRWITDRNLSPGEGLPKEAELQQLFGVGRGTMREALKALEVQGLIRLTTGPSGGAV
IERVTFDRTFQFLQNYLFFEDITIGDMYALRTILEPEMAALAVPHLGEKEFDALERSIAMSDPREENIQPAAVQRIEDLH
FHDILADACPNPLLRFQCRLINRMLETMVVSALHATQEEHRRLGEASWKAHRQILAAARDADVSQVRKLMLAHIVENQRH
LDLLQSGLRRRLVLDSDLRLGGAPLPQVRPMRAPAPRTRKGA

Sequences:

>Translated_282_residues
MASVSKKQVSQRGPKRGDLVVEEIKRWITDRNLSPGEGLPKEAELQQLFGVGRGTMREALKALEVQGLIRLTTGPSGGAV
IERVTFDRTFQFLQNYLFFEDITIGDMYALRTILEPEMAALAVPHLGEKEFDALERSIAMSDPREENIQPAAVQRIEDLH
FHDILADACPNPLLRFQCRLINRMLETMVVSALHATQEEHRRLGEASWKAHRQILAAARDADVSQVRKLMLAHIVENQRH
LDLLQSGLRRRLVLDSDLRLGGAPLPQVRPMRAPAPRTRKGA
>Mature_281_residues
ASVSKKQVSQRGPKRGDLVVEEIKRWITDRNLSPGEGLPKEAELQQLFGVGRGTMREALKALEVQGLIRLTTGPSGGAVI
ERVTFDRTFQFLQNYLFFEDITIGDMYALRTILEPEMAALAVPHLGEKEFDALERSIAMSDPREENIQPAAVQRIEDLHF
HDILADACPNPLLRFQCRLINRMLETMVVSALHATQEEHRRLGEASWKAHRQILAAARDADVSQVRKLMLAHIVENQRHL
DLLQSGLRRRLVLDSDLRLGGAPLPQVRPMRAPAPRTRKGA

Specific function: Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789621, Length=231, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 31769; Mature: 31638

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASVSKKQVSQRGPKRGDLVVEEIKRWITDRNLSPGEGLPKEAELQQLFGVGRGTMREAL
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHH
KALEVQGLIRLTTGPSGGAVIERVTFDRTFQFLQNYLFFEDITIGDMYALRTILEPEMAA
HHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHH
LAVPHLGEKEFDALERSIAMSDPREENIQPAAVQRIEDLHFHDILADACPNPLLRFQCRL
HHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
INRMLETMVVSALHATQEEHRRLGEASWKAHRQILAAARDADVSQVRKLMLAHIVENQRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHH
LDLLQSGLRRRLVLDSDLRLGGAPLPQVRPMRAPAPRTRKGA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ASVSKKQVSQRGPKRGDLVVEEIKRWITDRNLSPGEGLPKEAELQQLFGVGRGTMREAL
CCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHH
KALEVQGLIRLTTGPSGGAVIERVTFDRTFQFLQNYLFFEDITIGDMYALRTILEPEMAA
HHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHH
LAVPHLGEKEFDALERSIAMSDPREENIQPAAVQRIEDLHFHDILADACPNPLLRFQCRL
HHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
INRMLETMVVSALHATQEEHRRLGEASWKAHRQILAAARDADVSQVRKLMLAHIVENQRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHH
LDLLQSGLRRRLVLDSDLRLGGAPLPQVRPMRAPAPRTRKGA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA