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The map label for this gene is fabH [H]

Identifier: 120612443

GI number: 120612443

Start: 4223023

End: 4223973

Strand: Direct

Name: fabH [H]

Synonym: Aave_3802

Alternate gene names: 120612443

Gene position: 4223023-4223973 (Clockwise)

Preceding gene: 120612442

Following gene: 120612444

Centisome position: 78.89

GC content: 65.62

Gene sequence:

>951_bases
ATGAACGCATCCGCCACATGCACCCTTCCCGCGGTCGGCATACCGTACATCGCATGCTACCTGCCCGACCGGCTCGTGTC
CGTGGAGGAATGGGGACGGCGCAACGGGCACTCGCAAGAGCGCATCCGGTCGATGCTGCGCAACGGCGTGCGCTGCTTCC
ACGATGCCCGCTCGGAGGCGCCCACGGACATGGCCGCCAGAGCGGTACGGCTGCTGATGGTCAAGGGAGCGCTGCATCCG
GACAGCGTGGATCTGCTGATCTACACCCACACGCTGCAAAGCAGCGTGGCGCCTCCGCCGGCCAGTTCCGCAGGTCTCGT
TCAGGCGGCCTGCGGACTGAAGAAGGCATTGGGCTTTTCCGTATCCCAGCAGAACTGCGTATCGCCGATGATGGCGCTGC
ACGTCGCGCGAAGCATGATGGCCCGCAACCGGTCCATCCGCCGCGCGGTGATCGTCACGGCGGACCGGATGGGCGTGGCG
ACCGATCCCATCCGGGGCATCCTGGACCTGGCGCTGCACAGCGACGGCGCGTGTGCGTTCCTGGTCGAGCGCGATTCCGC
GCGCAACCAGGTGCTCGGCTACCACTTCTTCACCGACGGGCGCTTCTTCCAGGGCACGGATGAGAACCACGAGGTCGTGC
CCGACGAGAAGTACCACTGGTCCACCTTCTCGACGATCCGCAGCGCGCTGCAACGCGCCGGCCTGCAGGCGCAGGACATC
GATCGCATCCTGCCGAACCATGTGAACATGGAAGGCTGGCGGTTGGTGCTTGGCATGCTCAAGCTGCCCGAGGAGCGGCT
CTTCACGCGCAACGTGGGTCCCATGGGACACGTGTTCGGCAGTGATCCATTCATCAATCTGGCGCACGAGAACAAGCGGC
CCGGCGGCAACTATGTTCTCTTCTCGAGCGGGCTGGCGGGCTGCTTCGGCACCCTCGTGCTGCGCCATTGA

Upstream 100 bases:

>100_bases
CGGCTCCGCGGGACGGCGATTGCTTGGTGGTCTGGGGCATCGGCTTCGGGGGCGCACTGGCGTGCGCGCTGTTGCAATTC
GCCGCAGGGGGAGTGCCACG

Downstream 100 bases:

>100_bases
CGGAGCCGGCGATGCGACCGACCGACCCGAGCAGCCAGCACGCCCCGGCACATGCGCCCTGGCGTTCCGAAGCGCGCGCC
TCGCTGTCACTGACCCTCCA

Product: 3-oxoacyl-(ACP) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MNASATCTLPAVGIPYIACYLPDRLVSVEEWGRRNGHSQERIRSMLRNGVRCFHDARSEAPTDMAARAVRLLMVKGALHP
DSVDLLIYTHTLQSSVAPPPASSAGLVQAACGLKKALGFSVSQQNCVSPMMALHVARSMMARNRSIRRAVIVTADRMGVA
TDPIRGILDLALHSDGACAFLVERDSARNQVLGYHFFTDGRFFQGTDENHEVVPDEKYHWSTFSTIRSALQRAGLQAQDI
DRILPNHVNMEGWRLVLGMLKLPEERLFTRNVGPMGHVFGSDPFINLAHENKRPGGNYVLFSSGLAGCFGTLVLRH

Sequences:

>Translated_316_residues
MNASATCTLPAVGIPYIACYLPDRLVSVEEWGRRNGHSQERIRSMLRNGVRCFHDARSEAPTDMAARAVRLLMVKGALHP
DSVDLLIYTHTLQSSVAPPPASSAGLVQAACGLKKALGFSVSQQNCVSPMMALHVARSMMARNRSIRRAVIVTADRMGVA
TDPIRGILDLALHSDGACAFLVERDSARNQVLGYHFFTDGRFFQGTDENHEVVPDEKYHWSTFSTIRSALQRAGLQAQDI
DRILPNHVNMEGWRLVLGMLKLPEERLFTRNVGPMGHVFGSDPFINLAHENKRPGGNYVLFSSGLAGCFGTLVLRH
>Mature_316_residues
MNASATCTLPAVGIPYIACYLPDRLVSVEEWGRRNGHSQERIRSMLRNGVRCFHDARSEAPTDMAARAVRLLMVKGALHP
DSVDLLIYTHTLQSSVAPPPASSAGLVQAACGLKKALGFSVSQQNCVSPMMALHVARSMMARNRSIRRAVIVTADRMGVA
TDPIRGILDLALHSDGACAFLVERDSARNQVLGYHFFTDGRFFQGTDENHEVVPDEKYHWSTFSTIRSALQRAGLQAQDI
DRILPNHVNMEGWRLVLGMLKLPEERLFTRNVGPMGHVFGSDPFINLAHENKRPGGNYVLFSSGLAGCFGTLVLRH

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 34804; Mature: 34804

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASATCTLPAVGIPYIACYLPDRLVSVEEWGRRNGHSQERIRSMLRNGVRCFHDARSEA
CCCCCEEEECCCCHHHHEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
PTDMAARAVRLLMVKGALHPDSVDLLIYTHTLQSSVAPPPASSAGLVQAACGLKKALGFS
CHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHCCC
VSQQNCVSPMMALHVARSMMARNRSIRRAVIVTADRMGVATDPIRGILDLALHSDGACAF
CCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEE
LVERDSARNQVLGYHFFTDGRFFQGTDENHEVVPDEKYHWSTFSTIRSALQRAGLQAQDI
EEECCCCCCCEEEEEEEECCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHH
DRILPNHVNMEGWRLVLGMLKLPEERLFTRNVGPMGHVFGSDPFINLAHENKRPGGNYVL
HHHCCCCCCCHHHHHHHHHHHCCHHHHHHCCCCCCCHHCCCCCEEEECCCCCCCCCCEEE
FSSGLAGCFGTLVLRH
ECCCHHHHHHHHHHCC
>Mature Secondary Structure
MNASATCTLPAVGIPYIACYLPDRLVSVEEWGRRNGHSQERIRSMLRNGVRCFHDARSEA
CCCCCEEEECCCCHHHHEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
PTDMAARAVRLLMVKGALHPDSVDLLIYTHTLQSSVAPPPASSAGLVQAACGLKKALGFS
CHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHCCC
VSQQNCVSPMMALHVARSMMARNRSIRRAVIVTADRMGVATDPIRGILDLALHSDGACAF
CCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEE
LVERDSARNQVLGYHFFTDGRFFQGTDENHEVVPDEKYHWSTFSTIRSALQRAGLQAQDI
EEECCCCCCCEEEEEEEECCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHH
DRILPNHVNMEGWRLVLGMLKLPEERLFTRNVGPMGHVFGSDPFINLAHENKRPGGNYVL
HHHCCCCCCCHHHHHHHHHHHCCHHHHHHCCCCCCCHHCCCCCEEEECCCCCCCCCCEEE
FSSGLAGCFGTLVLRH
ECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA