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The map label for this gene is grsT [H]

Identifier: 120612378

GI number: 120612378

Start: 4144786

End: 4145562

Strand: Reverse

Name: grsT [H]

Synonym: Aave_3735

Alternate gene names: 120612378

Gene position: 4145562-4144786 (Counterclockwise)

Preceding gene: 120612379

Following gene: 120612377

Centisome position: 77.45

GC content: 76.83

Gene sequence:

>777_bases
ATGGCCATGGCGAGCGATGCGGACCTGGTGCTGCTGTGCCTGCCCTGCGCGGGCGCGAGCGCGACGATGTACCTGCGCTG
GCAGCGGCGCCTGCCCCCCGGGATGCGGGTGGTGCCGGTGGAGCTGCCCGGCCGCGGTGCGCGCATGGGCGAGCCGTTCG
CGCGGTCGTACGCCGATCTCGTCGGCCCGCTGGCGGAGGGGTGCCTGCGCGCCGCCGGGGGGGCCGCGTTCGCGCTTTTC
GGGCACAGCATGGGGGCGCTGCTCGCCTATGGCGTCGCCTGCCGCATGGCGGCCCTGGGCGGTGCCGTGCCCGCGGCACT
GGCCGTGTCGGCCTGCGCCGCGCCCGCGCTGCGCAGCGGCGAGCGCTATGCGGAGCCGCTGGACGACGCGCGCCTCATCG
CGGACCTGCGCGAGCAGGGCGGCACGCCGGAGGCGGTGTTCGCCGAGCCTGAGCTGCTGCGCATCACCCTCGACGTGCTG
CGGGCGGACTACCGCCTGTGCCATGGTTTCCGCCGGCCGGACGACGTGGAGGGTGCGGAGGGCACGGCGCCGCTGTCCTG
CCCCGTCCACATCTTCGGCGGGCGCGCCGACCGCATCGCCGCGGCCGAACTGCAGGCCTGGGCGCGCGAGACGCGCGGCC
CTTCGACCCTGGACTGGTTTGGCGGCGGGCACTTTTTCCTGCGCGAGGAGGAGGACCGCTTCCTGCGGACCCTGGCCGCG
CGCATGACGGCACCGGGGGCGGCGCGCGGCGCGCGGTCCCTGGCGGCCACCGCCTGA

Upstream 100 bases:

>100_bases
CCTGGACCGACATGCGGCCGAAGTCGCTGCGCGACTGGATGGCGCAGCAGGACGCCGGGGCCGCGGCAGAAGGTTCCACC
GCCGCGGCGGCCTGACGGCG

Downstream 100 bases:

>100_bases
CCGCGGCCACCCATTTTTCCTGCTTCCTTTTCTGGTTTCCCGCGCTGCCTGGCGCCGCGGGCTGGCAGCGCCTTTGCGCG
CACGAGGAGTTCCACATGAA

Product: thioesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MAMASDADLVLLCLPCAGASATMYLRWQRRLPPGMRVVPVELPGRGARMGEPFARSYADLVGPLAEGCLRAAGGAAFALF
GHSMGALLAYGVACRMAALGGAVPAALAVSACAAPALRSGERYAEPLDDARLIADLREQGGTPEAVFAEPELLRITLDVL
RADYRLCHGFRRPDDVEGAEGTAPLSCPVHIFGGRADRIAAAELQAWARETRGPSTLDWFGGGHFFLREEEDRFLRTLAA
RMTAPGAARGARSLAATA

Sequences:

>Translated_258_residues
MAMASDADLVLLCLPCAGASATMYLRWQRRLPPGMRVVPVELPGRGARMGEPFARSYADLVGPLAEGCLRAAGGAAFALF
GHSMGALLAYGVACRMAALGGAVPAALAVSACAAPALRSGERYAEPLDDARLIADLREQGGTPEAVFAEPELLRITLDVL
RADYRLCHGFRRPDDVEGAEGTAPLSCPVHIFGGRADRIAAAELQAWARETRGPSTLDWFGGGHFFLREEEDRFLRTLAA
RMTAPGAARGARSLAATA
>Mature_257_residues
AMASDADLVLLCLPCAGASATMYLRWQRRLPPGMRVVPVELPGRGARMGEPFARSYADLVGPLAEGCLRAAGGAAFALFG
HSMGALLAYGVACRMAALGGAVPAALAVSACAAPALRSGERYAEPLDDARLIADLREQGGTPEAVFAEPELLRITLDVLR
ADYRLCHGFRRPDDVEGAEGTAPLSCPVHIFGGRADRIAAAELQAWARETRGPSTLDWFGGGHFFLREEEDRFLRTLAAR
MTAPGAARGARSLAATA

Specific function: Probable thioesterase involved in the biosynthesis of gramicidin S [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioesterase family [H]

Homologues:

Organism=Homo sapiens, GI89257335, Length=224, Percent_Identity=26.3392857142857, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI8922871, Length=227, Percent_Identity=26.431718061674, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 27222; Mature: 27090

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMASDADLVLLCLPCAGASATMYLRWQRRLPPGMRVVPVELPGRGARMGEPFARSYADL
CCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHH
VGPLAEGCLRAAGGAAFALFGHSMGALLAYGVACRMAALGGAVPAALAVSACAAPALRSG
HHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
ERYAEPLDDARLIADLREQGGTPEAVFAEPELLRITLDVLRADYRLCHGFRRPDDVEGAE
CHHHCCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GTAPLSCPVHIFGGRADRIAAAELQAWARETRGPSTLDWFGGGHFFLREEEDRFLRTLAA
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEECHHHHHHHHHHH
RMTAPGAARGARSLAATA
HHCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
AMASDADLVLLCLPCAGASATMYLRWQRRLPPGMRVVPVELPGRGARMGEPFARSYADL
CCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHH
VGPLAEGCLRAAGGAAFALFGHSMGALLAYGVACRMAALGGAVPAALAVSACAAPALRSG
HHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
ERYAEPLDDARLIADLREQGGTPEAVFAEPELLRITLDVLRADYRLCHGFRRPDDVEGAE
CHHHCCCHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GTAPLSCPVHIFGGRADRIAAAELQAWARETRGPSTLDWFGGGHFFLREEEDRFLRTLAA
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEECHHHHHHHHHHH
RMTAPGAARGARSLAATA
HHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2477357; 7512553 [H]