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The map label for this gene is astC [H]

Identifier: 120612360

GI number: 120612360

Start: 4104257

End: 4105513

Strand: Reverse

Name: astC [H]

Synonym: Aave_3717

Alternate gene names: 120612360

Gene position: 4105513-4104257 (Counterclockwise)

Preceding gene: 120612361

Following gene: 120612359

Centisome position: 76.7

GC content: 61.97

Gene sequence:

>1257_bases
ATGCACGCCATGTCTAGATTCCGCGGTTACTGGCCGCCTTATACCCCCATGGGCTGCGATGACCATCGGCCAAAGATCGT
GCGGGGCGAAGGAGCCTATCTCTACGACGATGCAGGGCGGCGCTACCTGGATGGCATATCGGGCAGTTACAACCATTGCC
TGGGCCATTCCCACCCGGCCCTGATCGATGCGGTCAAGCAGCAGATGGATACGCTGGTCCACGCGTGCAATATCGGTTCG
AACACGGTACTGCCGGAGGCCCTCGCGGAACGGCTCATCGATGCGTCTGCACCCATGGGGCTCGCGCACATGTTCCTCGT
GGGCAGCGGCAGCGAGGGGGTCGAGGCCGCGTTGAAGATGGCGTGGCAATACCAGGTCAACCGTGGGCGCCCACAGCGCA
CGCATGTGGTGGCCATCGATGGCGCCTATCACGGCTGCACGCTGGGGGCGATGATCGCGACGCGGCGTGCCTTCATCAAC
GAAGGAGCGCTGCCACTGGTCGCGGCTTGCTCGTTAACGATGCCCCCGCCACGCGGCAACGACGACCTGGCGGCATGGGA
AGCACTTCTGGCCGAACATGGCTCGACCGTGGCAGCGATCATCGTCGAGCCGGTGATGGCGATCGCAGGAACACGCCAGT
TCCCGGAGGGCTTCCTGCGATCGTTGTCTTCGCTCGCCAGGGCCCACGATATTCCCCTGATTTGCGACGAAGTCTATTGC
GGGATCGGCCGAACCGGCGTCTTGTGCGAGTCGTTCTCCCAGGGCGCCAGCCCTGACATCGTCATTTTCAGCAAGAATCT
TGGAGGCGGTTTCCCCATCACCGCCGTAATGGCCACGGCCCACATCGCGGACAGCTTCTCATCACAACCTGTCCCGCTCC
TCCGGCATGGGCACACGCAGTCCGGCAATCTTCTGGGCTGTCGTGCTGCCTTGTTCATTCTGGATTATCTGCACGCACAG
GACTGCTTCGAAAAAGTTCGAACGAACGGCACACGGCTGCTGCAGTGGATTCGCGAGAAGTTGCCGACAGTCGATGACAC
CGTTACCGCCCAAGGAAAAGGGCTGATGCTGTCGATCAGTTTCGATTCAGCCGATACCTGCAGGCGTGTGCAAAACGACG
CGCGCCGGCAGGGTTTGATCGCCGGGGCTGCAGATCGGCACCTGAAGCTCGCTCCCCCTTTCACCATCGATGACTCCGGG
ATGGAAGAGCTGGTCCACCATCTGATCCGGGCCATAGGCAACGCGCCGCGCCATTGA

Upstream 100 bases:

>100_bases
GCGAGGCTCGTCCCCGGAACAGGAAAAAAAGAAACATCGTCGATGGCATCGGCGATCGAGAACATTCATCAATTGAAATC
CGAACTTCAGGGGACGCCGT

Downstream 100 bases:

>100_bases
TTTATTGTTGTGCGAAGAAACATATGACATCGGGATATTTCTCGCTCGGGCAGATCGCCGGGGGCACGCTCCATCACACC
CCTTTCAACTGGGGGGAACT

Product: aminotransferase

Products: NA

Alternate protein names: Carbon starvation protein C; Succinylornithine aminotransferase [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MHAMSRFRGYWPPYTPMGCDDHRPKIVRGEGAYLYDDAGRRYLDGISGSYNHCLGHSHPALIDAVKQQMDTLVHACNIGS
NTVLPEALAERLIDASAPMGLAHMFLVGSGSEGVEAALKMAWQYQVNRGRPQRTHVVAIDGAYHGCTLGAMIATRRAFIN
EGALPLVAACSLTMPPPRGNDDLAAWEALLAEHGSTVAAIIVEPVMAIAGTRQFPEGFLRSLSSLARAHDIPLICDEVYC
GIGRTGVLCESFSQGASPDIVIFSKNLGGGFPITAVMATAHIADSFSSQPVPLLRHGHTQSGNLLGCRAALFILDYLHAQ
DCFEKVRTNGTRLLQWIREKLPTVDDTVTAQGKGLMLSISFDSADTCRRVQNDARRQGLIAGAADRHLKLAPPFTIDDSG
MEELVHHLIRAIGNAPRH

Sequences:

>Translated_418_residues
MHAMSRFRGYWPPYTPMGCDDHRPKIVRGEGAYLYDDAGRRYLDGISGSYNHCLGHSHPALIDAVKQQMDTLVHACNIGS
NTVLPEALAERLIDASAPMGLAHMFLVGSGSEGVEAALKMAWQYQVNRGRPQRTHVVAIDGAYHGCTLGAMIATRRAFIN
EGALPLVAACSLTMPPPRGNDDLAAWEALLAEHGSTVAAIIVEPVMAIAGTRQFPEGFLRSLSSLARAHDIPLICDEVYC
GIGRTGVLCESFSQGASPDIVIFSKNLGGGFPITAVMATAHIADSFSSQPVPLLRHGHTQSGNLLGCRAALFILDYLHAQ
DCFEKVRTNGTRLLQWIREKLPTVDDTVTAQGKGLMLSISFDSADTCRRVQNDARRQGLIAGAADRHLKLAPPFTIDDSG
MEELVHHLIRAIGNAPRH
>Mature_418_residues
MHAMSRFRGYWPPYTPMGCDDHRPKIVRGEGAYLYDDAGRRYLDGISGSYNHCLGHSHPALIDAVKQQMDTLVHACNIGS
NTVLPEALAERLIDASAPMGLAHMFLVGSGSEGVEAALKMAWQYQVNRGRPQRTHVVAIDGAYHGCTLGAMIATRRAFIN
EGALPLVAACSLTMPPPRGNDDLAAWEALLAEHGSTVAAIIVEPVMAIAGTRQFPEGFLRSLSSLARAHDIPLICDEVYC
GIGRTGVLCESFSQGASPDIVIFSKNLGGGFPITAVMATAHIADSFSSQPVPLLRHGHTQSGNLLGCRAALFILDYLHAQ
DCFEKVRTNGTRLLQWIREKLPTVDDTVTAQGKGLMLSISFDSADTCRRVQNDARRQGLIAGAADRHLKLAPPFTIDDSG
MEELVHHLIRAIGNAPRH

Specific function: Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=396, Percent_Identity=30.3030303030303, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI13994255, Length=416, Percent_Identity=28.6057692307692, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI37574042, Length=420, Percent_Identity=25.952380952381, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI226442705, Length=420, Percent_Identity=25, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI284507298, Length=317, Percent_Identity=29.6529968454259, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI226442709, Length=391, Percent_Identity=25.0639386189258, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1789759, Length=394, Percent_Identity=29.6954314720812, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1788044, Length=393, Percent_Identity=30.2798982188295, Blast_Score=151, Evalue=9e-38,
Organism=Escherichia coli, GI145693181, Length=388, Percent_Identity=30.1546391752577, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1789016, Length=401, Percent_Identity=29.925187032419, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI1786991, Length=423, Percent_Identity=29.7872340425532, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1787560, Length=411, Percent_Identity=29.9270072992701, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1786349, Length=358, Percent_Identity=26.8156424581006, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25144271, Length=417, Percent_Identity=27.8177458033573, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI32564660, Length=438, Percent_Identity=27.1689497716895, Blast_Score=134, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI71992977, Length=429, Percent_Identity=23.5431235431235, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI25144274, Length=242, Percent_Identity=28.5123966942149, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17541228, Length=411, Percent_Identity=25.7907542579075, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6324432, Length=409, Percent_Identity=30.0733496332518, Blast_Score=160, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6323470, Length=413, Percent_Identity=27.1186440677966, Blast_Score=134, Evalue=4e-32,
Organism=Drosophila melanogaster, GI21357415, Length=397, Percent_Identity=27.7078085642317, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI28574759, Length=419, Percent_Identity=27.6849642004773, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI161085790, Length=419, Percent_Identity=27.4463007159904, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21356575, Length=421, Percent_Identity=27.790973871734, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI281366494, Length=376, Percent_Identity=25.531914893617, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24667139, Length=376, Percent_Identity=25.531914893617, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24667143, Length=376, Percent_Identity=25.531914893617, Blast_Score=89, Evalue=8e-18,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.81 [H]

Molecular weight: Translated: 45190; Mature: 45190

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAMSRFRGYWPPYTPMGCDDHRPKIVRGEGAYLYDDAGRRYLDGISGSYNHCLGHSHPA
CCCHHHHCCCCCCCCCCCCCCCCCCEEECCCCEEECCCCCHHHHCCCCCHHHHCCCCCHH
LIDAVKQQMDTLVHACNIGSNTVLPEALAERLIDASAPMGLAHMFLVGSGSEGVEAALKM
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHH
AWQYQVNRGRPQRTHVVAIDGAYHGCTLGAMIATRRAFINEGALPLVAACSLTMPPPRGN
HHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCC
DDLAAWEALLAEHGSTVAAIIVEPVMAIAGTRQFPEGFLRSLSSLARAHDIPLICDEVYC
CHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHH
GIGRTGVLCESFSQGASPDIVIFSKNLGGGFPITAVMATAHIADSFSSQPVPLLRHGHTQ
CCCCCHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCC
SGNLLGCRAALFILDYLHAQDCFEKVRTNGTRLLQWIREKLPTVDDTVTAQGKGLMLSIS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEECCCCEEEEEE
FDSADTCRRVQNDARRQGLIAGAADRHLKLAPPFTIDDSGMEELVHHLIRAIGNAPRH
CCCHHHHHHHHHHHHHCCCEECCCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MHAMSRFRGYWPPYTPMGCDDHRPKIVRGEGAYLYDDAGRRYLDGISGSYNHCLGHSHPA
CCCHHHHCCCCCCCCCCCCCCCCCCEEECCCCEEECCCCCHHHHCCCCCHHHHCCCCCHH
LIDAVKQQMDTLVHACNIGSNTVLPEALAERLIDASAPMGLAHMFLVGSGSEGVEAALKM
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHH
AWQYQVNRGRPQRTHVVAIDGAYHGCTLGAMIATRRAFINEGALPLVAACSLTMPPPRGN
HHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCC
DDLAAWEALLAEHGSTVAAIIVEPVMAIAGTRQFPEGFLRSLSSLARAHDIPLICDEVYC
CHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHH
GIGRTGVLCESFSQGASPDIVIFSKNLGGGFPITAVMATAHIADSFSSQPVPLLRHGHTQ
CCCCCHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCC
SGNLLGCRAALFILDYLHAQDCFEKVRTNGTRLLQWIREKLPTVDDTVTAQGKGLMLSIS
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEECCCCEEEEEE
FDSADTCRRVQNDARRQGLIAGAADRHLKLAPPFTIDDSGMEELVHHLIRAIGNAPRH
CCCHHHHHHHHHHHHHCCCEECCCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]