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The map label for this gene is hipO [H]

Identifier: 120612321

GI number: 120612321

Start: 4053682

End: 4054881

Strand: Reverse

Name: hipO [H]

Synonym: Aave_3677

Alternate gene names: 120612321

Gene position: 4054881-4053682 (Counterclockwise)

Preceding gene: 120612322

Following gene: 120612319

Centisome position: 75.75

GC content: 67.33

Gene sequence:

>1200_bases
ATGATCGATTCCGTGGATCGCCCCGGCTCGTACACGCGCATTGACCAGCTGCTGCCCTATGAGCAGGAACTGGTGGCGGT
GCGCCGGCACCTGCACCAGAACCCCGAACTGGCCTTTGGAGAGCATGCGACGTCCGACTTCATTGCCGGCAAGCTGGCCG
AATGGGGATACGACGTCACCCGCGGGATCGGCGGCACCGGCGTGGTGGGCCGCCTGCGCCATGGCGAAGGCTCGAAGACC
CTGGGCATCCGGGCGGACATGGACGCGTTGCCGATCCAGGAAGCCACCGGCGTCCCGTACGCCAGCTGCGCCCCCGGTTT
GATGCATGCGTGCGGCCACGACGGTCACATGGCCATGTTGCTCGGCGCGGCGAAATATCTGGCCCGGCACCGCAATTTTT
CCGGCACGCTGCACCTGATCTTCCAGCCGGCCGAGGAGCGTGGCTTCGACAGTGGCGGCAAGGCGATGGTCGCGGACGGC
CTGTTCGAGCTGTTTCCCTGCGATGCGGTCTTCGCGTTGCACAACCATCCGGGCCTGCCCCAGGGGCGCTTCCTCATGCG
CAGCGGTCCGTTCATGGCCGCGGGCGACCGGGTGTTCGTCAAGGTGTCGGGCATCGGCGGGCACGCCGCCAGGCCCCATC
TCGCCATCGATCCCCTGGTCGCAGCGTCCGCCATCGTCATGAGCCTGCAGACGGTCGTGGCCCGCAACGTCGATCCTTCG
GAGCCGGCCGTGGTCACCGTGGGGCGCCTTCGTGCAGGTGACGCGCTGAACGTCATCCCCGCCGACGCGGAAATCGGCAT
CAGCGTGAGATCCTTTTCTCCCGAGGTGCGCGCGCTGCTCAAGGAGCGCATCACCGCTCTCGTGGCTGGGGTCGCGCAGG
CGCACGGTTGCAGCGCCGATATCGATTACGTGGAGGGTTACCCGGTCGTCGTGAACGATGCTGCCGCGGTGGATCTCGCC
CGGCAGGTGGCCGTCGACCTGGTCGGGCCTGGCGCCGTGGACGCCGGATTTCCTCCGCTCATGGGAAGTGAAGACTTCGC
CTACATGCTGCAGCGCTGCCCAGGAGCGCTGGTGCGCATCGGCAACGGGCCTGCGGACGGTGGGCGTGGCCTCCACAATC
CCCGGTACGACTTCAATGACCTCAACCTGCCCTATGGGGCAGCCTTCTGGTGCCAGCTCGCGGAGCGCTTCCTTCGGTGA

Upstream 100 bases:

>100_bases
TGGTGCCCGAGGACGTGAAGCCACAGGCCTACCGGGCGGAGATCGTCGAGCGCATCAGGTTTTACCAGCGCATCGCCAAG
GCAAACAACATCGTGCTGGA

Downstream 100 bases:

>100_bases
CGCGGGCGTCCGGGGCCGGCTGACGGGAGAGATGCCTGCAGCGAGCAGGCCGGGCTGGTCGCCTCGGTTTCAGTCGTTCC
GACGGAACAGCGCCATCCGG

Product: amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MIDSVDRPGSYTRIDQLLPYEQELVAVRRHLHQNPELAFGEHATSDFIAGKLAEWGYDVTRGIGGTGVVGRLRHGEGSKT
LGIRADMDALPIQEATGVPYASCAPGLMHACGHDGHMAMLLGAAKYLARHRNFSGTLHLIFQPAEERGFDSGGKAMVADG
LFELFPCDAVFALHNHPGLPQGRFLMRSGPFMAAGDRVFVKVSGIGGHAARPHLAIDPLVAASAIVMSLQTVVARNVDPS
EPAVVTVGRLRAGDALNVIPADAEIGISVRSFSPEVRALLKERITALVAGVAQAHGCSADIDYVEGYPVVVNDAAAVDLA
RQVAVDLVGPGAVDAGFPPLMGSEDFAYMLQRCPGALVRIGNGPADGGRGLHNPRYDFNDLNLPYGAAFWCQLAERFLR

Sequences:

>Translated_399_residues
MIDSVDRPGSYTRIDQLLPYEQELVAVRRHLHQNPELAFGEHATSDFIAGKLAEWGYDVTRGIGGTGVVGRLRHGEGSKT
LGIRADMDALPIQEATGVPYASCAPGLMHACGHDGHMAMLLGAAKYLARHRNFSGTLHLIFQPAEERGFDSGGKAMVADG
LFELFPCDAVFALHNHPGLPQGRFLMRSGPFMAAGDRVFVKVSGIGGHAARPHLAIDPLVAASAIVMSLQTVVARNVDPS
EPAVVTVGRLRAGDALNVIPADAEIGISVRSFSPEVRALLKERITALVAGVAQAHGCSADIDYVEGYPVVVNDAAAVDLA
RQVAVDLVGPGAVDAGFPPLMGSEDFAYMLQRCPGALVRIGNGPADGGRGLHNPRYDFNDLNLPYGAAFWCQLAERFLR
>Mature_399_residues
MIDSVDRPGSYTRIDQLLPYEQELVAVRRHLHQNPELAFGEHATSDFIAGKLAEWGYDVTRGIGGTGVVGRLRHGEGSKT
LGIRADMDALPIQEATGVPYASCAPGLMHACGHDGHMAMLLGAAKYLARHRNFSGTLHLIFQPAEERGFDSGGKAMVADG
LFELFPCDAVFALHNHPGLPQGRFLMRSGPFMAAGDRVFVKVSGIGGHAARPHLAIDPLVAASAIVMSLQTVVARNVDPS
EPAVVTVGRLRAGDALNVIPADAEIGISVRSFSPEVRALLKERITALVAGVAQAHGCSADIDYVEGYPVVVNDAAAVDLA
RQVAVDLVGPGAVDAGFPPLMGSEDFAYMLQRCPGALVRIGNGPADGGRGLHNPRYDFNDLNLPYGAAFWCQLAERFLR

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=345, Percent_Identity=30.1449275362319, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 42415; Mature: 42415

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDSVDRPGSYTRIDQLLPYEQELVAVRRHLHQNPELAFGEHATSDFIAGKLAEWGYDVT
CCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHCCCHHH
RGIGGTGVVGRLRHGEGSKTLGIRADMDALPIQEATGVPYASCAPGLMHACGHDGHMAML
HCCCCCCCEEEEECCCCCCEEEEEECCCCCCCHHHCCCCCHHCCHHHHHHCCCCCCHHHH
LGAAKYLARHRNFSGTLHLIFQPAEERGFDSGGKAMVADGLFELFPCDAVFALHNHPGLP
HHHHHHHHHHCCCCCEEEEEEECHHHCCCCCCCCEEHHHHHHHHCCCCEEEEECCCCCCC
QGRFLMRSGPFMAAGDRVFVKVSGIGGHAARPHLAIDPLVAASAIVMSLQTVVARNVDPS
CCCEEEECCCCEEECCEEEEEEECCCCCCCCCCCEECHHHHHHHHHHHHHHHHHCCCCCC
EPAVVTVGRLRAGDALNVIPADAEIGISVRSFSPEVRALLKERITALVAGVAQAHGCSAD
CCCEEEEECCCCCCCCEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
IDYVEGYPVVVNDAAAVDLARQVAVDLVGPGAVDAGFPPLMGSEDFAYMLQRCPGALVRI
CHHHCCCCEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEE
GNGPADGGRGLHNPRYDFNDLNLPYGAAFWCQLAERFLR
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDSVDRPGSYTRIDQLLPYEQELVAVRRHLHQNPELAFGEHATSDFIAGKLAEWGYDVT
CCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHCCCHHH
RGIGGTGVVGRLRHGEGSKTLGIRADMDALPIQEATGVPYASCAPGLMHACGHDGHMAML
HCCCCCCCEEEEECCCCCCEEEEEECCCCCCCHHHCCCCCHHCCHHHHHHCCCCCCHHHH
LGAAKYLARHRNFSGTLHLIFQPAEERGFDSGGKAMVADGLFELFPCDAVFALHNHPGLP
HHHHHHHHHHCCCCCEEEEEEECHHHCCCCCCCCEEHHHHHHHHCCCCEEEEECCCCCCC
QGRFLMRSGPFMAAGDRVFVKVSGIGGHAARPHLAIDPLVAASAIVMSLQTVVARNVDPS
CCCEEEECCCCEEECCEEEEEEECCCCCCCCCCCEECHHHHHHHHHHHHHHHHHCCCCCC
EPAVVTVGRLRAGDALNVIPADAEIGISVRSFSPEVRALLKERITALVAGVAQAHGCSAD
CCCEEEEECCCCCCCCEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
IDYVEGYPVVVNDAAAVDLARQVAVDLVGPGAVDAGFPPLMGSEDFAYMLQRCPGALVRI
CHHHCCCCEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEE
GNGPADGGRGLHNPRYDFNDLNLPYGAAFWCQLAERFLR
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]