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The map label for this gene is lrhA [H]

Identifier: 120612116

GI number: 120612116

Start: 3827412

End: 3828329

Strand: Reverse

Name: lrhA [H]

Synonym: Aave_3463

Alternate gene names: 120612116

Gene position: 3828329-3827412 (Counterclockwise)

Preceding gene: 120612118

Following gene: 120612115

Centisome position: 71.52

GC content: 76.14

Gene sequence:

>918_bases
ATGCGCCCCTTCAACCTGGAACAACTCAGGACGTTCGTCGCGGTGGCCGATGCCGGCAGCCTGGCCGCCGGTGCGCCGCA
GGTCTTCCTGTCGCAGTCGGCCGTGAGCGAGCAATTGCGCAAGCTCGAGCAGCATGCCGGCCAGGCGCTGCTGGTGCGCT
CCAAGGCCGGCGTGGCGCCCACCGCCGCCGGGCTGCGGCTGCTGGCGCACGCCCGGCAGTTGCTGACGCTGAGCGAGTCG
GCATGGCACGACCTGCGCGGCGCGCGGCTGGAGGGCGCGCTGCGGCTGGGCGTCACCGACTATTTCCGTCCCGCGGAGCT
GGCGGGGCTGCTGGCGCGCATGCAGGCCCGGCACCCTGGCGTGCGGCTGCAGGTCACGGTGCAAAAGAGCGGCGACGTCG
AGGCCGGCTACGCCCGGGGCGCGTTCGATGTCGGCATCGCCATGCGCCTGCCGGCCCCTGCCGCCGGCCGCTCCGCCGGT
GCGCCGGCCCCGGCCCGCGGCGGGCAGGTGCTGCGGCGCGAGCCCCTGCACTGGATGGGCGCCGCGCAGATTGCCGCCGC
GCCGCCCGGCCGGGAGGAACCCCTGCGCCTGCTGGCACTGCCGGACACCTGCGCCCTCCACCAGTTCACGGCGGCCTTGC
TGCGCCGGCGGCGCATTCCGTTCACGGTCGCGCTCATGGCCTCCGGGGTCGCCGGCCTGCAATCCGCGCTGGCGGCCGGG
CTCGGCATCGCCTGCCTGAACGCCGCCGCGCTGTGCGAGGGCGTGCAGGTCCTGCCCGCGGCCTGGGGGCTTCCGGCGCT
GCCCCAGGCCCGGTTCATCGTGCTGCCGCCGCGCCCGGGCGAATCCGCCTTCGTCCGCAACGCCCGCGAGCAACTGGCAA
CCGACTTCGGGCAGGCCCCGGCGCGCGCGGCACGCTAG

Upstream 100 bases:

>100_bases
CCTGGGGCCGGGTTGGAATGGTTCCGATTCTTCGGCTTTCCACGCCATCGGAAAAGCAGGATGATCGGCAGTCATCCATC
GAAAATTCCGTGGGATCGAC

Downstream 100 bases:

>100_bases
CGCCCCGGCTTCGGTGGCGCAGGGCTTTCGCTGCCGCCGGCGGGCTGCCGCAGGCGGTCGTTGCGGACCTCCTTCATCAT
CTCCTCGCCGACCGGATCGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MRPFNLEQLRTFVAVADAGSLAAGAPQVFLSQSAVSEQLRKLEQHAGQALLVRSKAGVAPTAAGLRLLAHARQLLTLSES
AWHDLRGARLEGALRLGVTDYFRPAELAGLLARMQARHPGVRLQVTVQKSGDVEAGYARGAFDVGIAMRLPAPAAGRSAG
APAPARGGQVLRREPLHWMGAAQIAAAPPGREEPLRLLALPDTCALHQFTAALLRRRRIPFTVALMASGVAGLQSALAAG
LGIACLNAAALCEGVQVLPAAWGLPALPQARFIVLPPRPGESAFVRNAREQLATDFGQAPARAAR

Sequences:

>Translated_305_residues
MRPFNLEQLRTFVAVADAGSLAAGAPQVFLSQSAVSEQLRKLEQHAGQALLVRSKAGVAPTAAGLRLLAHARQLLTLSES
AWHDLRGARLEGALRLGVTDYFRPAELAGLLARMQARHPGVRLQVTVQKSGDVEAGYARGAFDVGIAMRLPAPAAGRSAG
APAPARGGQVLRREPLHWMGAAQIAAAPPGREEPLRLLALPDTCALHQFTAALLRRRRIPFTVALMASGVAGLQSALAAG
LGIACLNAAALCEGVQVLPAAWGLPALPQARFIVLPPRPGESAFVRNAREQLATDFGQAPARAAR
>Mature_305_residues
MRPFNLEQLRTFVAVADAGSLAAGAPQVFLSQSAVSEQLRKLEQHAGQALLVRSKAGVAPTAAGLRLLAHARQLLTLSES
AWHDLRGARLEGALRLGVTDYFRPAELAGLLARMQARHPGVRLQVTVQKSGDVEAGYARGAFDVGIAMRLPAPAAGRSAG
APAPARGGQVLRREPLHWMGAAQIAAAPPGREEPLRLLALPDTCALHQFTAALLRRRRIPFTVALMASGVAGLQSALAAG
LGIACLNAAALCEGVQVLPAAWGLPALPQARFIVLPPRPGESAFVRNAREQLATDFGQAPARAAR

Specific function: Not known, does not seem to act on the proton translocating NADH dehydrogenase genes (nuoA-N) which are part of the lrhA operon [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=271, Percent_Identity=30.2583025830258, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788297, Length=270, Percent_Identity=28.1481481481481, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786713, Length=148, Percent_Identity=29.7297297297297, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI157672245, Length=144, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787879, Length=306, Percent_Identity=26.797385620915, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789204, Length=262, Percent_Identity=25.1908396946565, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32005; Mature: 32005

Theoretical pI: Translated: 11.81; Mature: 11.81

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPFNLEQLRTFVAVADAGSLAAGAPQVFLSQSAVSEQLRKLEQHAGQALLVRSKAGVAP
CCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCH
TAAGLRLLAHARQLLTLSESAWHDLRGARLEGALRLGVTDYFRPAELAGLLARMQARHPG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCEEEECCHHCCCHHHHHHHHHHHHHCCCC
VRLQVTVQKSGDVEAGYARGAFDVGIAMRLPAPAAGRSAGAPAPARGGQVLRREPLHWMG
EEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHCCCHHHC
AAQIAAAPPGREEPLRLLALPDTCALHQFTAALLRRRRIPFTVALMASGVAGLQSALAAG
CHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCEEHHHHHHCHHHHHHHHHHH
LGIACLNAAALCEGVQVLPAAWGLPALPQARFIVLPPRPGESAFVRNAREQLATDFGQAP
HHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCC
ARAAR
CCCCC
>Mature Secondary Structure
MRPFNLEQLRTFVAVADAGSLAAGAPQVFLSQSAVSEQLRKLEQHAGQALLVRSKAGVAP
CCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCH
TAAGLRLLAHARQLLTLSESAWHDLRGARLEGALRLGVTDYFRPAELAGLLARMQARHPG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCEEEECCHHCCCHHHHHHHHHHHHHCCCC
VRLQVTVQKSGDVEAGYARGAFDVGIAMRLPAPAAGRSAGAPAPARGGQVLRREPLHWMG
EEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHCCCHHHC
AAQIAAAPPGREEPLRLLALPDTCALHQFTAALLRRRRIPFTVALMASGVAGLQSALAAG
CHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCEEHHHHHHCHHHHHHHHHHH
LGIACLNAAALCEGVQVLPAAWGLPALPQARFIVLPPRPGESAFVRNAREQLATDFGQAP
HHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCC
ARAAR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]