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The map label for this gene is livK [C]

Identifier: 120612055

GI number: 120612055

Start: 3757666

End: 3758805

Strand: Direct

Name: livK [C]

Synonym: Aave_3401

Alternate gene names: 120612055

Gene position: 3757666-3758805 (Clockwise)

Preceding gene: 120612054

Following gene: 120612060

Centisome position: 70.2

GC content: 66.23

Gene sequence:

>1140_bases
ATGAGCAAGACCCAAACGATATTCCGCCTGACCGCCATGGCCCTGGGACTGGCCTGCGCGGCCGCCCATGCCCAGGCACA
GGAGCGTGTCCGCATCGGCTTCATGAGCCCCGTCACGGGCCCGCAGGCGGCCAACGGAGGAGACAACCGCGACGGCGCCC
TGCTCGCCATCAAGGAACTGAACGCCAAGGGCGTCAAGGTGGCCGGCAAGCCCGTGGTGTTCGAGCTGGACATCAACGAC
GACGTGGCCGATCCCAAGCAGGGCGTGCAGGTCGCCCAGACACTTGCCGACAAGAAGATCCGCTTCGTGCTCGGCCCCTA
CAACTCGGGCGTCACGGTGCCCGCCGCGCGGGTGCTGAACGACTCGGACATCCTCACGCTCACCGTGGCCTCCAACCCGA
AGATCACGGAACTCGGCTACGGCACGCTGTTCCGCATCGGCGCCAGCGACAACCAGCTGGGCACCAAGATGGCCACCTAC
GCGGCGCAGGACCTGAAGCTCAAGACGGTGGCCGTGATCGACGACCGCACCGCCTACGGCCAGGGCGTCGCGCGCGAATT
CACGGCGCAGGCCAGGCGCCTGGGCCTGCAGGTCGTGGCCACCGAATTCACCACCGACAAGGCCACGGATTTCAGCGCCA
TCCTGACCAACATCCGCGGCGCCAAGGCCGAGGCCGTGTTCTACGGTGGCTACTCGCCCCAGGGCGGCCCCCTGCTCAAG
CAGATGCGCGCCCTCGGCATCACCGGGCCCCTGCTCGGCGGCGACGGCATCTGCTCCACCGAGACCGCCAACCTGGCCCA
GCTCACCGGTGACCTGAACGTCTATTGCACCCAGGGCGGCTCGCTGCTGGACAAGAGCGACAAGGGCCAGAAATTCGCCG
AGCGCTACCGCGCCGAATACAAGCGGGACCCGCTCACCTATGCCGCCGCCTTCTACGACGGCATGTACCTGCTGGCCAAC
GCCATGGAGTCGACCCAGTCCACCACCGACACGAAGAAGATCGCCCAGGCGATCGCCAATGGCAAATATGCCGGCGTGAC
GGGCGAGTTTTCGTACGACGTCAAGCACGACCTGAAGTTGTCGGCGGTGACGGTGTACACCTTCAAGGGCAAGGACGTGG
TGCCGCTGAAGAGCCTGTAA

Upstream 100 bases:

>100_bases
CGGTCCGCCCGGCCACGAGCCAGGCAGGCCTTCCTGCCTGCCGGGGCACCAGGCCCATACGATCGCCGTGCCCCATCCCT
GCATCACAAGGAACATGCCA

Downstream 100 bases:

>100_bases
GCAGGACGGCCCCGGGGCCGCCTGGGGCCGGCGCCTGCGAGCAGCAGCCTTCCGGCAATGAAGCCGCTGCGGCGTAAGGC
GTCAGGCATGGGGCCGAGCA

Product: extracellular ligand-binding receptor

Products: ADP; phosphate; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MSKTQTIFRLTAMALGLACAAAHAQAQERVRIGFMSPVTGPQAANGGDNRDGALLAIKELNAKGVKVAGKPVVFELDIND
DVADPKQGVQVAQTLADKKIRFVLGPYNSGVTVPAARVLNDSDILTLTVASNPKITELGYGTLFRIGASDNQLGTKMATY
AAQDLKLKTVAVIDDRTAYGQGVAREFTAQARRLGLQVVATEFTTDKATDFSAILTNIRGAKAEAVFYGGYSPQGGPLLK
QMRALGITGPLLGGDGICSTETANLAQLTGDLNVYCTQGGSLLDKSDKGQKFAERYRAEYKRDPLTYAAAFYDGMYLLAN
AMESTQSTTDTKKIAQAIANGKYAGVTGEFSYDVKHDLKLSAVTVYTFKGKDVVPLKSL

Sequences:

>Translated_379_residues
MSKTQTIFRLTAMALGLACAAAHAQAQERVRIGFMSPVTGPQAANGGDNRDGALLAIKELNAKGVKVAGKPVVFELDIND
DVADPKQGVQVAQTLADKKIRFVLGPYNSGVTVPAARVLNDSDILTLTVASNPKITELGYGTLFRIGASDNQLGTKMATY
AAQDLKLKTVAVIDDRTAYGQGVAREFTAQARRLGLQVVATEFTTDKATDFSAILTNIRGAKAEAVFYGGYSPQGGPLLK
QMRALGITGPLLGGDGICSTETANLAQLTGDLNVYCTQGGSLLDKSDKGQKFAERYRAEYKRDPLTYAAAFYDGMYLLAN
AMESTQSTTDTKKIAQAIANGKYAGVTGEFSYDVKHDLKLSAVTVYTFKGKDVVPLKSL
>Mature_378_residues
SKTQTIFRLTAMALGLACAAAHAQAQERVRIGFMSPVTGPQAANGGDNRDGALLAIKELNAKGVKVAGKPVVFELDINDD
VADPKQGVQVAQTLADKKIRFVLGPYNSGVTVPAARVLNDSDILTLTVASNPKITELGYGTLFRIGASDNQLGTKMATYA
AQDLKLKTVAVIDDRTAYGQGVAREFTAQARRLGLQVVATEFTTDKATDFSAILTNIRGAKAEAVFYGGYSPQGGPLLKQ
MRALGITGPLLGGDGICSTETANLAQLTGDLNVYCTQGGSLLDKSDKGQKFAERYRAEYKRDPLTYAAAFYDGMYLLANA
MESTQSTTDTKKIAQAIANGKYAGVTGEFSYDVKHDLKLSAVTVYTFKGKDVVPLKSL

Specific function: Component of an amino-acid transport system (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leucine-binding protein family [H]

Homologues:

Organism=Escherichia coli, GI1789867, Length=357, Percent_Identity=30.812324929972, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI48994941, Length=354, Percent_Identity=26.8361581920904, Blast_Score=129, Evalue=2e-31,

Paralogues:

None

Copy number: 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001828
- InterPro:   IPR000709 [H]

Pfam domain/function: PF01094 ANF_receptor [H]

EC number: NA

Molecular weight: Translated: 40306; Mature: 40175

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTQTIFRLTAMALGLACAAAHAQAQERVRIGFMSPVTGPQAANGGDNRDGALLAIKEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCEEEEEEEC
NAKGVKVAGKPVVFELDINDDVADPKQGVQVAQTLADKKIRFVLGPYNSGVTVPAARVLN
CCCCEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHCC
DSDILTLTVASNPKITELGYGTLFRIGASDNQLGTKMATYAAQDLKLKTVAVIDDRTAYG
CCCEEEEEEECCCCEEEECCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEEEEECCCHHC
QGVAREFTAQARRLGLQVVATEFTTDKATDFSAILTNIRGAKAEAVFYGGYSPQGGPLLK
CCHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCHHHH
QMRALGITGPLLGGDGICSTETANLAQLTGDLNVYCTQGGSLLDKSDKGQKFAERYRAEY
HHHHHCCCCCCCCCCCCCCCCCCCHHEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHH
KRDPLTYAAAFYDGMYLLANAMESTQSTTDTKKIAQAIANGKYAGVTGEFSYDVKHDLKL
CCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCEECCCCCEEECCCCCCEE
SAVTVYTFKGKDVVPLKSL
EEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
SKTQTIFRLTAMALGLACAAAHAQAQERVRIGFMSPVTGPQAANGGDNRDGALLAIKEL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCEEEEEEEC
NAKGVKVAGKPVVFELDINDDVADPKQGVQVAQTLADKKIRFVLGPYNSGVTVPAARVLN
CCCCEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHCC
DSDILTLTVASNPKITELGYGTLFRIGASDNQLGTKMATYAAQDLKLKTVAVIDDRTAYG
CCCEEEEEEECCCCEEEECCCEEEEECCCCCCHHHHHHHHHHCCCEEEEEEEEECCCHHC
QGVAREFTAQARRLGLQVVATEFTTDKATDFSAILTNIRGAKAEAVFYGGYSPQGGPLLK
CCHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCHHHH
QMRALGITGPLLGGDGICSTETANLAQLTGDLNVYCTQGGSLLDKSDKGQKFAERYRAEY
HHHHHCCCCCCCCCCCCCCCCCCCHHEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHHH
KRDPLTYAAAFYDGMYLLANAMESTQSTTDTKKIAQAIANGKYAGVTGEFSYDVKHDLKL
CCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCEECCCCCEEECCCCCCEE
SAVTVYTFKGKDVVPLKSL
EEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA