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The map label for this gene is hsdM [C]

Identifier: 120612013

GI number: 120612013

Start: 3714751

End: 3716880

Strand: Reverse

Name: hsdM [C]

Synonym: Aave_3359

Alternate gene names: 120612013

Gene position: 3716880-3714751 (Counterclockwise)

Preceding gene: 120612014

Following gene: 120612012

Centisome position: 69.44

GC content: 62.86

Gene sequence:

>2130_bases
ATGAGCGTTAACTTTCAGCAACTCGCCAATTTCATCTGGTCGGTAGCCGACCTGCTGCGTGGCCCCTATCGTCCGCCGCA
GTACGAGCGCGTCATGCTGCCGCTCACGGTGCTGCGTCGCTTCGATGCCGTACTGGCACCGAGCAAGGAGGCCGTGCTCA
AGCGCTACGAGCCGCTCAGGGCGAAGAACATCCCGAACATCGACGCCATCCTCAACAACCTGGCCAAGGATGAGGGCGGC
ACCCCGCTGGGTTTTCATAACCACAGCCAGCTTGACTTCCAAAAGCTCAAGGGCGACCCCGATAACATCGGTCGCCACTT
GGCCGACTACATCGCCGGCTTCTCAGAGAACGTCCGCAAGATCTTCGAACGCTTCGAGTTCGACAAGGAGATCGAGAAGC
TCGAAGAGTCCAACCGTCTCTACCAGGTGGTGTCCCAGTTCGCCGAGATCGACCTGCACCCCAAGCGGGTGGACAACATC
ACCATGGGGCTGGTGTTCGAAGACCTGATCCGGCGCTTCAACGAAGCCGCCAACGAAACGGCGGGCGATCACTTCACTCC
GCGCGAAGTGATCCAGCTCATGGTCAACCTGCTGCTGGAGCCCGACACTAGCGTGCTCACCCAGGCCGGCGTCATCGTCA
CCATCTGCGACCCGGCCTGCGGTACCGGCGGCATGCTGGCCGAGGCGCAGAACTGGATTCGCGCCCACAACGAGCAGGCC
ACGGTCAAGGTCTTCGGGCAGGACTACAACCCACGCTCCTATGCCGTGGCCGCCTCCGATCTCTTGATCAAAGGCCACAA
GGACGGCCAAGTGGTGCTGGGCAACACCCTCACCGACGACCCCTTTCCGGAGCAGCGCTTCGACTACCTGCTGGCCAACC
CGCCCTTCGGCGTGGACTGGAAGGCTGAGAAGAAGGTCATCGACCGCTGGCCTAACTTCCGTGGCTACAGCGGCAAGCTG
CCACGCATCAACGACGGCGCCCTGTTGTTCCTGCTCTACATGATGAGCAAGTTCCAGGAGTACAAGCCTGGAAGCCGCGA
CAAGCCTGGCTCGCGAACGGCCGTCGTCTTCAATGGCTCGCCGCTGTTCACCGGCGGTGCGGGCAGCGGCGAGAGCGACA
TCCGCCGCTGGATCATCGAGCGTGACCAGTTGGAGGCCATCGTCGCCTTGCCCGAGCAGATGTTCTACAACACGGGTATC
GGCACCTTCATCTGGGTGGTCACCAATCGCAAGGCCTCGCACCGCAAGAGCAAGATCCAGCTCATCGACGCCCGCGAACG
CTACACACCAATGAAGCGCAGCCTGGGCGACAAGCGCCGCTACCTCGACCAGGCTGCGCTTGATGACGTCACCCGCGAAC
ACGGCGCGCTGGAAGACAGCAAGACCAGCCGCGTCTTCGACAACGCCGACTTCGGGTACCGCCGCATCACAGTGCTGCGC
CCGCTGCGCCTGCGCTTCCAGATCACCGATGAGACGCGCGAGCGCTTCCTCAATGTCTGCCCCGAGCTGTTCGACGCGCT
GCAGGCTGTGCAGGAAGACCTCGGCACCGAGCCGCTGCTGGACTGGAACCAGGCCTGGGGCGCCGTGCAGCAGGTATTTA
AGGCCCTGCCCGACAACATCGATGGCTGGGCCAAGGGCGCCAAGGGCACCGCGCAAAAGAAGATCTTCCGCGACTGCTTC
ACCGTGGTCGATCCCGAGGCCGCGCCCGTCGTCGACAAGCACCACAAGATCGAGCCGCTCGACTGTGCCGCTCTGTTCCC
CGGGCAGACGCTCCCCGCCGACCTCTGCAAGGATGATCTGTACGAGTTGCTGGGCCTGCACGCCGACGGCAAGGGAAAAC
ACATCGAGTACGTGCCTGACCCGGCGCTCAAGGATGCCGAGAACATCCCGCTGAAAGAGGACATCGTCAGCTACGTGCTG
CGCGAGGTGCGGACCTACGTGCCGGATGCCTGGATCGACCGCGCCACGCTGGACGAGCAGGACGGCGGCATCGGCAAGGT
GGGCTACGAGATTAACTTCAACCGCGTGTTCTTCCAGTACCAGCCGCCACGCCCGCTGCATGAGATCGATGCGGAGCTTG
CGGAAGTTGAGAAGCGGATTCTCGATTTGCTGCGGGAGGTGACGGAGTGA

Upstream 100 bases:

>100_bases
TTGAGCACTACGACGGGACCGACGCTGAAACCAAACGGATCGTGCCGTTGAAGCGGCTGTACTGGCCGGCCTAACCAAAA
AAGAAGATGGTTCAATAACA

Downstream 100 bases:

>100_bases
ACACATCGACTGTGCGAGTCGATCCTGAAGTGTGGCGATTGGCACGCTTGAAATTCGTTGCACCTTTACGAAACGAACGC
ATGTCCGCCGGTTCCGACCA

Product: N-6 DNA methylase

Products: NA

Alternate protein names: M.MjaXP [H]

Number of amino acids: Translated: 709; Mature: 708

Protein sequence:

>709_residues
MSVNFQQLANFIWSVADLLRGPYRPPQYERVMLPLTVLRRFDAVLAPSKEAVLKRYEPLRAKNIPNIDAILNNLAKDEGG
TPLGFHNHSQLDFQKLKGDPDNIGRHLADYIAGFSENVRKIFERFEFDKEIEKLEESNRLYQVVSQFAEIDLHPKRVDNI
TMGLVFEDLIRRFNEAANETAGDHFTPREVIQLMVNLLLEPDTSVLTQAGVIVTICDPACGTGGMLAEAQNWIRAHNEQA
TVKVFGQDYNPRSYAVAASDLLIKGHKDGQVVLGNTLTDDPFPEQRFDYLLANPPFGVDWKAEKKVIDRWPNFRGYSGKL
PRINDGALLFLLYMMSKFQEYKPGSRDKPGSRTAVVFNGSPLFTGGAGSGESDIRRWIIERDQLEAIVALPEQMFYNTGI
GTFIWVVTNRKASHRKSKIQLIDARERYTPMKRSLGDKRRYLDQAALDDVTREHGALEDSKTSRVFDNADFGYRRITVLR
PLRLRFQITDETRERFLNVCPELFDALQAVQEDLGTEPLLDWNQAWGAVQQVFKALPDNIDGWAKGAKGTAQKKIFRDCF
TVVDPEAAPVVDKHHKIEPLDCAALFPGQTLPADLCKDDLYELLGLHADGKGKHIEYVPDPALKDAENIPLKEDIVSYVL
REVRTYVPDAWIDRATLDEQDGGIGKVGYEINFNRVFFQYQPPRPLHEIDAELAEVEKRILDLLREVTE

Sequences:

>Translated_709_residues
MSVNFQQLANFIWSVADLLRGPYRPPQYERVMLPLTVLRRFDAVLAPSKEAVLKRYEPLRAKNIPNIDAILNNLAKDEGG
TPLGFHNHSQLDFQKLKGDPDNIGRHLADYIAGFSENVRKIFERFEFDKEIEKLEESNRLYQVVSQFAEIDLHPKRVDNI
TMGLVFEDLIRRFNEAANETAGDHFTPREVIQLMVNLLLEPDTSVLTQAGVIVTICDPACGTGGMLAEAQNWIRAHNEQA
TVKVFGQDYNPRSYAVAASDLLIKGHKDGQVVLGNTLTDDPFPEQRFDYLLANPPFGVDWKAEKKVIDRWPNFRGYSGKL
PRINDGALLFLLYMMSKFQEYKPGSRDKPGSRTAVVFNGSPLFTGGAGSGESDIRRWIIERDQLEAIVALPEQMFYNTGI
GTFIWVVTNRKASHRKSKIQLIDARERYTPMKRSLGDKRRYLDQAALDDVTREHGALEDSKTSRVFDNADFGYRRITVLR
PLRLRFQITDETRERFLNVCPELFDALQAVQEDLGTEPLLDWNQAWGAVQQVFKALPDNIDGWAKGAKGTAQKKIFRDCF
TVVDPEAAPVVDKHHKIEPLDCAALFPGQTLPADLCKDDLYELLGLHADGKGKHIEYVPDPALKDAENIPLKEDIVSYVL
REVRTYVPDAWIDRATLDEQDGGIGKVGYEINFNRVFFQYQPPRPLHEIDAELAEVEKRILDLLREVTE
>Mature_708_residues
SVNFQQLANFIWSVADLLRGPYRPPQYERVMLPLTVLRRFDAVLAPSKEAVLKRYEPLRAKNIPNIDAILNNLAKDEGGT
PLGFHNHSQLDFQKLKGDPDNIGRHLADYIAGFSENVRKIFERFEFDKEIEKLEESNRLYQVVSQFAEIDLHPKRVDNIT
MGLVFEDLIRRFNEAANETAGDHFTPREVIQLMVNLLLEPDTSVLTQAGVIVTICDPACGTGGMLAEAQNWIRAHNEQAT
VKVFGQDYNPRSYAVAASDLLIKGHKDGQVVLGNTLTDDPFPEQRFDYLLANPPFGVDWKAEKKVIDRWPNFRGYSGKLP
RINDGALLFLLYMMSKFQEYKPGSRDKPGSRTAVVFNGSPLFTGGAGSGESDIRRWIIERDQLEAIVALPEQMFYNTGIG
TFIWVVTNRKASHRKSKIQLIDARERYTPMKRSLGDKRRYLDQAALDDVTREHGALEDSKTSRVFDNADFGYRRITVLRP
LRLRFQITDETRERFLNVCPELFDALQAVQEDLGTEPLLDWNQAWGAVQQVFKALPDNIDGWAKGAKGTAQKKIFRDCFT
VVDPEAAPVVDKHHKIEPLDCAALFPGQTLPADLCKDDLYELLGLHADGKGKHIEYVPDPALKDAENIPLKEDIVSYVLR
EVRTYVPDAWIDRATLDEQDGGIGKVGYEINFNRVFFQYQPPRPLHEIDAELAEVEKRILDLLREVTE

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 80586; Mature: 80455

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCEEEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVNFQQLANFIWSVADLLRGPYRPPQYERVMLPLTVLRRFDAVLAPSKEAVLKRYEPLR
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHH
AKNIPNIDAILNNLAKDEGGTPLGFHNHSQLDFQKLKGDPDNIGRHLADYIAGFSENVRK
HCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
IFERFEFDKEIEKLEESNRLYQVVSQFAEIDLHPKRVDNITMGLVFEDLIRRFNEAANET
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHHHHHHHHHHCCC
AGDHFTPREVIQLMVNLLLEPDTSVLTQAGVIVTICDPACGTGGMLAEAQNWIRAHNEQA
CCCCCCHHHHHHHHHHHHCCCCHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCC
TVKVFGQDYNPRSYAVAASDLLIKGHKDGQVVLGNTLTDDPFPEQRFDYLLANPPFGVDW
EEEEECCCCCCCCEEEEHHHEEEECCCCCCEEECCCCCCCCCCHHHHCEEECCCCCCCCC
KAEKKVIDRWPNFRGYSGKLPRINDGALLFLLYMMSKFQEYKPGSRDKPGSRTAVVFNGS
CHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCC
PLFTGGAGSGESDIRRWIIERDQLEAIVALPEQMFYNTGIGTFIWVVTNRKASHRKSKIQ
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHEE
LIDARERYTPMKRSLGDKRRYLDQAALDDVTREHGALEDSKTSRVFDNADFGYRRITVLR
EECCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCEEEEEEE
PLRLRFQITDETRERFLNVCPELFDALQAVQEDLGTEPLLDWNQAWGAVQQVFKALPDNI
CEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCC
DGWAKGAKGTAQKKIFRDCFTVVDPEAAPVVDKHHKIEPLDCAALFPGQTLPADLCKDDL
CHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHEECCCCCCCHHHHHHHH
YELLGLHADGKGKHIEYVPDPALKDAENIPLKEDIVSYVLREVRTYVPDAWIDRATLDEQ
HHHHCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCC
DGGIGKVGYEINFNRVFFQYQPPRPLHEIDAELAEVEKRILDLLREVTE
CCCCEEEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]