| Definition | Acidovorax citrulli AAC00-1 chromosome, complete genome. |
|---|---|
| Accession | NC_008752 |
| Length | 5,352,772 |
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The map label for this gene is yvrD [H]
Identifier: 120612003
GI number: 120612003
Start: 3703574
End: 3704356
Strand: Reverse
Name: yvrD [H]
Synonym: Aave_3349
Alternate gene names: 120612003
Gene position: 3704356-3703574 (Counterclockwise)
Preceding gene: 120612004
Following gene: 120612001
Centisome position: 69.2
GC content: 67.94
Gene sequence:
>783_bases ATGAGCTTCGACCTTCACCTGAAAGGCCTGCGGGCGGTGGTCACCGGCGGCACGCTGGGCCTTGGCGCCGCCGTTGTGAA AACCCTTGCGGAGGCCGGCGCGCGGGTCGCGACATCCGCGCGAACCGTGCCCGCCCAGCCGGTGGAGGGGGTGACTTACG TCGCCGCCGACCTGTCCACGGCGGAGGGCACGGGCCACCTGGCCCGGACCATCCTGCAGAATTGGGGCGGCATCGACATC CTGGTCAATGTGCTCGGCGGCTCGAAGACTCCCGGCGGCGGTTTCGCCGCGATCAGCGATGAGCACTGGTTCGCCGAGAT GAACCTGAACCTGATGCCTGCCGTACGGCTGGATCGTGCGTTGCTTCCAGCGATGCTGGCCCAAGGTTCGGGTGTCGTCA TCCACGTCAGCTCCATCCAGCGCGTGCTGCCCCTGCCGGAGTCCACGACCGCCTACGCCGCGGCCAAGGGGGCTCTCACG ACCTACAGCAAGTCGCTGGCAAGAGAAGTGACGCCCAAGGGCGTTCGCGTGCTGAGCGTTGCGCCGGGCTGGATCGAGAC CGAGGCTTCCGTCGCGTTTGCGGAGCGGATGGCTGCAGACGCCGGAACGGACTACGAGGGCGGCAAGAAAATCGTGATGG ACTGGCTCGGAGGAATTCCCGTGGGCCGGCCCGCCACACCGCATGAGGTGGCCGATCTGATCGCCTTCCTGGCCTCTCCG CGGGCCGCTTCGATCGCAGGGGCCGAATACCGGATCGACGGCGGCACGGTGCCCACGCTGTAG
Upstream 100 bases:
>100_bases TGCGCGCCAACGTCACCGGCGATTTTCCTGGCAGCCCGATCGCTCTGTCCTACCGCTTTCGGCTTGAACGCGGGCTGATC GCCTCGCTGGAGATCACGGC
Downstream 100 bases:
>100_bases CCCACAGGCTGGGCGTCCGGTGGCCTGGAAGTGTTTGCCGGGTTGGGTTCGATCGCACCCAAGGGAAGCTAACGTTCCAG CTCCGCCAGACGCATCGCCA
Product: short chain dehydrogenase
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 260; Mature: 259
Protein sequence:
>260_residues MSFDLHLKGLRAVVTGGTLGLGAAVVKTLAEAGARVATSARTVPAQPVEGVTYVAADLSTAEGTGHLARTILQNWGGIDI LVNVLGGSKTPGGGFAAISDEHWFAEMNLNLMPAVRLDRALLPAMLAQGSGVVIHVSSIQRVLPLPESTTAYAAAKGALT TYSKSLAREVTPKGVRVLSVAPGWIETEASVAFAERMAADAGTDYEGGKKIVMDWLGGIPVGRPATPHEVADLIAFLASP RAASIAGAEYRIDGGTVPTL
Sequences:
>Translated_260_residues MSFDLHLKGLRAVVTGGTLGLGAAVVKTLAEAGARVATSARTVPAQPVEGVTYVAADLSTAEGTGHLARTILQNWGGIDI LVNVLGGSKTPGGGFAAISDEHWFAEMNLNLMPAVRLDRALLPAMLAQGSGVVIHVSSIQRVLPLPESTTAYAAAKGALT TYSKSLAREVTPKGVRVLSVAPGWIETEASVAFAERMAADAGTDYEGGKKIVMDWLGGIPVGRPATPHEVADLIAFLASP RAASIAGAEYRIDGGTVPTL >Mature_259_residues SFDLHLKGLRAVVTGGTLGLGAAVVKTLAEAGARVATSARTVPAQPVEGVTYVAADLSTAEGTGHLARTILQNWGGIDIL VNVLGGSKTPGGGFAAISDEHWFAEMNLNLMPAVRLDRALLPAMLAQGSGVVIHVSSIQRVLPLPESTTAYAAAKGALTT YSKSLAREVTPKGVRVLSVAPGWIETEASVAFAERMAADAGTDYEGGKKIVMDWLGGIPVGRPATPHEVADLIAFLASPR AASIAGAEYRIDGGTVPTL
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=268, Percent_Identity=27.6119402985075, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI32483357, Length=257, Percent_Identity=29.9610894941634, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI66933014, Length=231, Percent_Identity=29.8701298701299, Blast_Score=85, Evalue=5e-17, Organism=Homo sapiens, GI40254992, Length=258, Percent_Identity=30.6201550387597, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI5031737, Length=254, Percent_Identity=29.5275590551181, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI7705925, Length=261, Percent_Identity=27.5862068965517, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI126723750, Length=258, Percent_Identity=27.1317829457364, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=33.6842105263158, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI20149619, Length=201, Percent_Identity=29.8507462686567, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI59889578, Length=235, Percent_Identity=28.0851063829787, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=260, Percent_Identity=32.6923076923077, Blast_Score=107, Evalue=7e-25, Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=28.1853281853282, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI1789208, Length=262, Percent_Identity=28.2442748091603, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI87082160, Length=265, Percent_Identity=28.3018867924528, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI1789378, Length=260, Percent_Identity=27.3076923076923, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1786812, Length=252, Percent_Identity=27.3809523809524, Blast_Score=71, Evalue=5e-14, Organism=Escherichia coli, GI1790717, Length=262, Percent_Identity=25.5725190839695, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI1788459, Length=258, Percent_Identity=28.6821705426357, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI1787905, Length=273, Percent_Identity=27.8388278388278, Blast_Score=64, Evalue=7e-12, Organism=Escherichia coli, GI2367175, Length=263, Percent_Identity=27.3764258555133, Blast_Score=62, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=31.8897637795276, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17562990, Length=272, Percent_Identity=30.8823529411765, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17563726, Length=269, Percent_Identity=29.7397769516729, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=31.4606741573034, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI71994604, Length=256, Percent_Identity=31.25, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17560332, Length=264, Percent_Identity=29.5454545454545, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=29.811320754717, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=30.188679245283, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI72000259, Length=271, Percent_Identity=27.3062730627306, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=29.2592592592593, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17565030, Length=261, Percent_Identity=31.4176245210728, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=29.5454545454545, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17560150, Length=267, Percent_Identity=29.2134831460674, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI71994600, Length=257, Percent_Identity=28.4046692607004, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=31.3207547169811, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI25147288, Length=259, Percent_Identity=29.3436293436293, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17562904, Length=271, Percent_Identity=26.9372693726937, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=30.9701492537313, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17538480, Length=271, Percent_Identity=28.0442804428044, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17544670, Length=272, Percent_Identity=26.1029411764706, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17561402, Length=265, Percent_Identity=27.1698113207547, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=28.8973384030418, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17555706, Length=253, Percent_Identity=27.6679841897233, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17560220, Length=271, Percent_Identity=27.6752767527675, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17508651, Length=260, Percent_Identity=29.2307692307692, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI115534694, Length=261, Percent_Identity=27.9693486590038, Blast_Score=68, Evalue=4e-12, Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=32.8063241106719, Blast_Score=104, Evalue=7e-23, Organism=Drosophila melanogaster, GI21355319, Length=265, Percent_Identity=30.188679245283, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI24644339, Length=266, Percent_Identity=30.4511278195489, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=30.0395256916996, Blast_Score=84, Evalue=7e-17, Organism=Drosophila melanogaster, GI21358495, Length=205, Percent_Identity=29.2682926829268, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=29.9610894941634, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24643142, Length=257, Percent_Identity=30.7392996108949, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI24584744, Length=201, Percent_Identity=27.8606965174129, Blast_Score=71, Evalue=9e-13, Organism=Drosophila melanogaster, GI28574402, Length=201, Percent_Identity=27.8606965174129, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24639444, Length=260, Percent_Identity=26.1538461538462, Blast_Score=68, Evalue=5e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 26734; Mature: 26603
Theoretical pI: Translated: 6.69; Mature: 6.69
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 1.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSFDLHLKGLRAVVTGGTLGLGAAVVKTLAEAGARVATSARTVPAQPVEGVTYVAADLST CCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCEEEEEEECCC AEGTGHLARTILQNWGGIDILVNVLGGSKTPGGGFAAISDEHWFAEMNLNLMPAVRLDRA CCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEECCCCEEEEECCCCCCHHHHHHH LLPAMLAQGSGVVIHVSSIQRVLPLPESTTAYAAAKGALTTYSKSLAREVTPKGVRVLSV HHHHHHHCCCCEEEECCCHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEE APGWIETEASVAFAERMAADAGTDYEGGKKIVMDWLGGIPVGRPATPHEVADLIAFLASP CCCCEECHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCC RAASIAGAEYRIDGGTVPTL CCCEECCCEEEECCCCCCCC >Mature Secondary Structure SFDLHLKGLRAVVTGGTLGLGAAVVKTLAEAGARVATSARTVPAQPVEGVTYVAADLST CCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCEEEEEEECCC AEGTGHLARTILQNWGGIDILVNVLGGSKTPGGGFAAISDEHWFAEMNLNLMPAVRLDRA CCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEECCCCEEEEECCCCCCHHHHHHH LLPAMLAQGSGVVIHVSSIQRVLPLPESTTAYAAAKGALTTYSKSLAREVTPKGVRVLSV HHHHHHHCCCCEEEECCCHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEE APGWIETEASVAFAERMAADAGTDYEGGKKIVMDWLGGIPVGRPATPHEVADLIAFLASP CCCCEECHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCC RAASIAGAEYRIDGGTVPTL CCCEECCCEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9639930; 9384377 [H]