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The map label for this gene is trxB [H]

Identifier: 120611991

GI number: 120611991

Start: 3687436

End: 3688359

Strand: Direct

Name: trxB [H]

Synonym: Aave_3336

Alternate gene names: 120611991

Gene position: 3687436-3688359 (Clockwise)

Preceding gene: 120611990

Following gene: 120611992

Centisome position: 68.89

GC content: 70.13

Gene sequence:

>924_bases
ATGCGATATGACACCATCATCGTCGGCGGAAGCTACGCGGGCATTGCTGCCGCCCTGCAGCTGGTGCGGGCCCGCCGATC
CGTGCTGGTGATCGACGCGGGCCAGCGCCGCAACCGCTTCGCCAGCCATTCGCACGGCTTCCTGGGCCAGGACGGCGTGC
CTCCGGAGGACATCGCGGCGAATGCGCGCCGGCAGCTCGCCGCCTATCCGTCTCTGAGCTGGCTGGAAGGGCGTGCCACG
GCCGTCACGGGGTCCGCGGATGCGTTCACGGTCACCACGTCCGACGGCGGTTCGCACCGTGCCCGCCGCATCCTGCTGGC
CACGGGCGTGGCCGACCGGCTTCCCGCCGTCGCAGGCCTTGCCGAACGCTGGGGCACGGCCGTCTTCCATTGCCCGTACT
GCCACGGCTACGAACTCGGCCAGGGCCGCATCGGCATCGTCGGCGCCAGTCCGCTGTCCGTCCACCAGGCCGAATTGCTC
ACCGACTGGGGCGATGTGACCCTGCTCGTCAACCGCGCGCTGGACCTGACCGACACGTCCCGCTCCACCCTCGCGCAACG
GGGGGTGGCCATCGAGGAAGCCCCCATCGACAGGATCGAAGGGCATGCCGACGTGGTAATGGCCGACGGACGGCAACTGC
GCTTCGCGGGCCTGTTCACGGCAACGCGCACGTCCCCCTCCAGTCCGCTCGCCGAAGCCATGGGCTGCGTGCTGGAAGAC
ACCCCGATGGGCACCCAGGTCCGCACCGATGCCGAGAACAAGACCTCGGTGGCCGGGGTGTTCGCCTGCGGCGACGTGGC
GAGAATCCCCCACTCGCTGTCCCTGGCCGTGGGCCACGGCGCCATGGCGGGCGCACAGGTCCATCGTTCGCTGGTGTGGC
CCGAAACCCTCGCACCGCAGCCAGTGGAAGACCGCATGCGATGA

Upstream 100 bases:

>100_bases
AGGCGCTGCTGCTGAAGCGGTTTTCGGAAATCACCCTCGCCGACCTGGCCGCCGACTTCGCGCGCCGGCATGCGGCAGCA
CGGCGCACCAGGAGTTGACC

Downstream 100 bases:

>100_bases
CCCCGTTCTCCGATCCTGCGGCCGTATCGGGCTACGCCGCGAGGACCGTGCGGATCGTGCCCGGCCTGCACGACCTGCAC
CGGATGGCCGGCGTTCTGCT

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MRYDTIIVGGSYAGIAAALQLVRARRSVLVIDAGQRRNRFASHSHGFLGQDGVPPEDIAANARRQLAAYPSLSWLEGRAT
AVTGSADAFTVTTSDGGSHRARRILLATGVADRLPAVAGLAERWGTAVFHCPYCHGYELGQGRIGIVGASPLSVHQAELL
TDWGDVTLLVNRALDLTDTSRSTLAQRGVAIEEAPIDRIEGHADVVMADGRQLRFAGLFTATRTSPSSPLAEAMGCVLED
TPMGTQVRTDAENKTSVAGVFACGDVARIPHSLSLAVGHGAMAGAQVHRSLVWPETLAPQPVEDRMR

Sequences:

>Translated_307_residues
MRYDTIIVGGSYAGIAAALQLVRARRSVLVIDAGQRRNRFASHSHGFLGQDGVPPEDIAANARRQLAAYPSLSWLEGRAT
AVTGSADAFTVTTSDGGSHRARRILLATGVADRLPAVAGLAERWGTAVFHCPYCHGYELGQGRIGIVGASPLSVHQAELL
TDWGDVTLLVNRALDLTDTSRSTLAQRGVAIEEAPIDRIEGHADVVMADGRQLRFAGLFTATRTSPSSPLAEAMGCVLED
TPMGTQVRTDAENKTSVAGVFACGDVARIPHSLSLAVGHGAMAGAQVHRSLVWPETLAPQPVEDRMR
>Mature_307_residues
MRYDTIIVGGSYAGIAAALQLVRARRSVLVIDAGQRRNRFASHSHGFLGQDGVPPEDIAANARRQLAAYPSLSWLEGRAT
AVTGSADAFTVTTSDGGSHRARRILLATGVADRLPAVAGLAERWGTAVFHCPYCHGYELGQGRIGIVGASPLSVHQAELL
TDWGDVTLLVNRALDLTDTSRSTLAQRGVAIEEAPIDRIEGHADVVMADGRQLRFAGLFTATRTSPSSPLAEAMGCVLED
TPMGTQVRTDAENKTSVAGVFACGDVARIPHSLSLAVGHGAMAGAQVHRSLVWPETLAPQPVEDRMR

Specific function: Serves To Protect The Cell Against DNA Damage By Alkyl Hydroperoxides. It Can Use Either NADH Or NADPH As Electron Donor For Direct Reduction Of Redox Dyes Or Of Alkyl Hydroperoxides When Combined With The Ahpc Protein. [C]

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 32522; Mature: 32522

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYDTIIVGGSYAGIAAALQLVRARRSVLVIDAGQRRNRFASHSHGFLGQDGVPPEDIAA
CCEEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCHHCHHHCCCCCCCCCCCCCHHHHHH
NARRQLAAYPSLSWLEGRATAVTGSADAFTVTTSDGGSHRARRILLATGVADRLPAVAGL
HHHHHHHCCCCCHHCCCCEEEEECCCCEEEEEECCCCCHHHEEEEEECCCHHHHHHHHHH
AERWGTAVFHCPYCHGYELGQGRIGIVGASPLSVHQAELLTDWGDVTLLVNRALDLTDTS
HHHCCCEEEECCCCCCEEECCCCEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCH
RSTLAQRGVAIEEAPIDRIEGHADVVMADGRQLRFAGLFTATRTSPSSPLAEAMGCVLED
HHHHHHCCCEEECCCHHHHCCCCEEEEECCCEEEEEEEEEECCCCCCCHHHHHHCCEEEC
TPMGTQVRTDAENKTSVAGVFACGDVARIPHSLSLAVGHGAMAGAQVHRSLVWPETLAPQ
CCCCCEEECCCCCCCCEEEEEECCCHHHCCCEEEEEECCCHHHHHHHHHHHCCCHHCCCC
PVEDRMR
CHHHHCC
>Mature Secondary Structure
MRYDTIIVGGSYAGIAAALQLVRARRSVLVIDAGQRRNRFASHSHGFLGQDGVPPEDIAA
CCEEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCHHCHHHCCCCCCCCCCCCCHHHHHH
NARRQLAAYPSLSWLEGRATAVTGSADAFTVTTSDGGSHRARRILLATGVADRLPAVAGL
HHHHHHHCCCCCHHCCCCEEEEECCCCEEEEEECCCCCHHHEEEEEECCCHHHHHHHHHH
AERWGTAVFHCPYCHGYELGQGRIGIVGASPLSVHQAELLTDWGDVTLLVNRALDLTDTS
HHHCCCEEEECCCCCCEEECCCCEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCH
RSTLAQRGVAIEEAPIDRIEGHADVVMADGRQLRFAGLFTATRTSPSSPLAEAMGCVLED
HHHHHHCCCEEECCCHHHHCCCCEEEEECCCEEEEEEEEEECCCCCCCHHHHHHCCEEEC
TPMGTQVRTDAENKTSVAGVFACGDVARIPHSLSLAVGHGAMAGAQVHRSLVWPETLAPQ
CCCCCEEECCCCCCCCEEEEEECCCHHHCCCEEEEEECCCHHHHHHHHHHHCCCHHCCCC
PVEDRMR
CHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]