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The map label for this gene is putA [H]

Identifier: 120611977

GI number: 120611977

Start: 3670033

End: 3673782

Strand: Direct

Name: putA [H]

Synonym: Aave_3321

Alternate gene names: 120611977

Gene position: 3670033-3673782 (Clockwise)

Preceding gene: 120611973

Following gene: 120611983

Centisome position: 68.56

GC content: 73.49

Gene sequence:

>3750_bases
ATGAACGCCCCGCACCCCTCCCTGCATACCCGGCCTTTCTCGGCCTTCGCGCCGCGGCCCGCGACTGCGGCCGCGCCGCT
GCGCGACGCGATCACCGCGGCCTGCCGCATTCCCGAGCCGGAGGCCGTCGCGCCCTTGCTGGAAGAAGCGCGCATCGACG
GTGCCGCGGCCCGGCGCGTGCATGCCCTGGCACTGCGGCTGGCCGGAGGCCTGCGCGAGCGCAAGGGCGCGGGCGGCCGG
GCCGGCTGGGTGCAGGGCCTGCTGCAGGAGTTCGCGCTCTCCTCGCAGGAGGGCGTGGCGCTGATGTGCCTGGCCGAAGC
CCTGCTGCGCATTCCCGACAGCGCCACGCGCGACGCGCTGATCCGAGACAAGATCGGTGGCGGCGACTGGGAGTCGCACC
TGGGCAAGAGCCCTTCGCTGTTCGTGAATGCGGCCACCTGGGGCCTGCTGCTGACCGGCAGGCTGGTGGCCACGCACAGC
GAACAAGGCCTGGGCGCGGCGCTGCGCCGCATCACGGCGCGCGGCGGCGAACCGCTGGTGCGCAAGGGCGTGGATGTGGC
CATGCGCATGATGGGCGAGCAGTTCGTGACCGGCGAGACCATCGCCCAGGCGCTGGCCAATGCCCGCCCGCGCGAGGCCC
AGGGCTTCCGCTATTCCTACGACATGCTGGGCGAAGCCGCGCTCACCGCGGCCGATGCCGAGCGCTACCTGCAGTCGTAC
GTGGACGCGATCCATGCCATCGGCAAGGCGTCCGCGGGCCGCGGCGTGTACGAGGGCCCCGGCATTTCCATCAAGCTGTC
GGCCCTGCATCCGCGCTACAGCCGGGCCCAGCACGGCCGGGTGATGCAGGAACTCCTCCCCCGCGTGCTGGGGCTGGCGG
AACTGGCGCGCGGCTACGACATCGGGCTGAACATCGACGCCGAGGAAGCCGACCGGCTGGAGATTTCGCTGGACCTGCTC
GAAGCGCTGTGCGCAGCGCCATCGCTTGCCGGCTGGAACGGGATCGGTTTCGTGATCCAGGCCTACCAGAAGCGCTGCCC
GTTCGTGATCGACCACGTGATCGATCTCGCGCGCCGCACCGGCCACCGCCTGATGGTGCGGCTGGTCAAGGGCGCGTACT
GGGACAGCGAGATCAAGCGGGCCCAGGTGGACGGGCTGGAGGACTACCCGGTCTATACGCGCAAGGTGCACACCGACGTG
TCCTACATCGCCTGCGCGCGCCGCCTGCTCGCGGCGCCGGACGCCGTCTATCCGCAGTTCGCCACGCACAACGCGCACAC
GCTGGCCGCCATCCACGAGCTGGCCGGCCCGGAGCGCTACACGCCGGGCCAGTACGAATTCCAGTGCCTGCACGGCATGG
GCGAGCCGCTGTACGAGCAGGTCGTGGGCGCTGCGGGGCTGGACCGGCCCTGCCGGGTCTATGCGCCCGTCGGCACGCAC
GAGACGCTGCTGGCCTACCTGGTGCGCCGGCTGCTGGAAAACGGCGCCAACACCTCGTTCGTGAACCGCGTGGCCGACGC
CACCCTGCCGCTGGAGACCCTGGTGGCCGACCCGGTGGCGGCGGTGGACGCGGAGCCGATGCCGGGTGAGGTGAACCCGC
GCATTCCGCTGCCGCCCGCGCTCTATGGCCCTGCGCGCCGCAATTCCGCAGGGCTGGACCTCGCGAGCGAAGCGGTCCTC
GCGCAGCTGTCCGATGCCCTGCAGCGCCACGCGTACCAGGACTGGGAGGCGGTACCGCTGCTCGCCGGGCCGGTGCAGGC
AGGACCTCGCCTGCCGGTACGCAACCCCGCCTGGCATGCGGACGTGGTGGGCACGGTGCAGGAGGCGAGCGCAGGCGACG
TGGACCAGGCGCTGGGGTGGGCGCAGGCGGCGGCCTCCGCCTGGGCCGCGACGCCCCCTGCGGAGCGGGCCGCCGCGCTG
CGCCGCGCCGCCGACGCGCTGGAGCAGCGCACACCCGCCCTGCTGTCGCTGCTGGTGCGCGAAGCGGGCAAGACCTGCGC
GAACGCCGTGGCGGAGGTGCGCGAGGCGGTGGACTTCCTGCGTTTCTATGCGGCCCAGGTGGAGACGCTGTTCGGCACGG
AAACAGGCAAAGACGCATGGGCGCCGCTCGGCCCCGTGGTATGCATCAGCCCCTGGAACTTCCCGCTCGCCATCTTCATG
GGGCAGGTGGCGGCCGCGCTCGCCGCCGGCAACGTGGTGCTGGCCAAGCCCGCCGAGCAGACGCCGCTGGTGGCGGCCGA
GGCGGTGCGCATCCTGCACGGCGCCGGCGTGCCGCGCGCGGCCGTGCAGTTGCTGCCCGGCCAGGGCGAGACCGTGGGTG
CCCGGCTGGTGGGCGACGGGCGCGTGATGGGCGTGCTGTTCACCGGCTCCACCGATGTGGCCCGCATCCTGCAGCGCAGC
GTGGCGGGCCGCCTGGACGCTACCGGCCGGCCGGTGCCGCTGATCGCCGAGACGGGCGGCCAGAACGCGATGATCGTGGA
TTCATCCGCCCTGGCGGAGCAGGTGGTGGCGGATGCCGTCGCCTCGGCCTTCGACAGCGCGGGACAGCGCTGCTCGGCGC
TGCGGGTGCTGTGCCTGCAGGAGGACGTGGCGGACCGCGTGCTGGAGATGCTGCGCGGCGCCATGGCGGAACTGCGCATC
GGGCGGCCCGACCAGCTCGCCACGGACGTGGGCCCCGTGATCGACGCCGAAGCGCGCGACGGCATCCTGCGCCACGTGGC
GGCCCTGCGCGAGCGTGGCCGCGCGGTGCACCAGGTGCCCGTGCCGCCGCATGCCGGGGCCGAGGGCACCTACGTGCCGC
CCACGCTGATCGAATTGAAGGACCTGTCGGAGCTGGAGCGCGAGGTCTTCGGCCCGGTCCTGCACGTGGTGCGCTATCCG
CGCAGCGGGCTGGACACGCTGCTGGACCGCATCGCGGGCACCGGCTACGGCCTCACCCAGGGCCTGCACACGCGCATCGA
CGAAACGGTGGAACGCGTGCTGCGCCGTGCCCGCGCGGGCAATCTCTACGTGAACCGCAACATGGTGGGCGCGGTCGTCG
GCGTGCAGCCCTTCGGCGGCGAGGGCCTGTCGGGCACGGGGCCGAAGGCCGGCGGTCCGCTGTACCTGCTGCGACTGGTG
GCACAGGCACCCGGCGGCGCTGCGCGGGCAGCCATCGCCGCGATGGCCGCCCCGGACACCGGTGAAGGCCATGCGCCCGC
CGCCCCGGCCCCGCTGCAGGCCCTGGCGGACTGGGCACGCAGCGCCGGCCAGGGCGCGCTGGAAGCGGCCTGCCGCCAGT
TCGCGCAGGACACGCCGGCCGGCAGCCTCCGCACGCTGCCCGGCCCCACGGGAGAGCGCAACCAATACGGCGTGGCACCG
CGCGAACGCATTCTTTGTCTGGCCGATGCCGATGCGGACCGGCTGCTGCAGCTGGCCGCCGTGCTGGCCGTGGACGGGCA
CGCCGTCTGGCCTTCGGCCGCGGCCACGCTGCGCGCTACTCTGCCGGCGACGGTGCAGGAGCGCATCGTGCTCGTGGCGG
ACTGGCGTGCGCCCGCGGTGGCCGTGGATGCCGTGCTGCACCATGGCACCGAGGCATCGCTGCGCGAGGTGTGCCAGGCG
ATGGCCGCGCGGCCGGGGCCGATCGTCGGCGTCGCGGGCCATGCGCCCGGCGATGCCGCGGTGCCGCTCGAACGCCTGGT
CCTGGAGCGCGCGGTCAGCATCAACACCGCGGCGGCCGGCGGCAATGCCAGCCTCATGACCATGGAGTGA

Upstream 100 bases:

>100_bases
TTCATTCATGATCGGTATTTTTGCGCATTAATTCAACCGACTCGGCGAGATGATCGCAGGCATTCACTCCACCTTCGTCC
CGCCCCCGGACCGCTCTGCC

Downstream 100 bases:

>100_bases
GCCGGCAGCCGGCCCCGGGCGGTCTCAGCCTTCGGCCACGGCCGGAGCCGGCCGCGACAGTCCCCGCACGACATGCACCA
CCTGCGGCTGGTCCACCAGC

Product: L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1249; Mature: 1249

Protein sequence:

>1249_residues
MNAPHPSLHTRPFSAFAPRPATAAAPLRDAITAACRIPEPEAVAPLLEEARIDGAAARRVHALALRLAGGLRERKGAGGR
AGWVQGLLQEFALSSQEGVALMCLAEALLRIPDSATRDALIRDKIGGGDWESHLGKSPSLFVNAATWGLLLTGRLVATHS
EQGLGAALRRITARGGEPLVRKGVDVAMRMMGEQFVTGETIAQALANARPREAQGFRYSYDMLGEAALTAADAERYLQSY
VDAIHAIGKASAGRGVYEGPGISIKLSALHPRYSRAQHGRVMQELLPRVLGLAELARGYDIGLNIDAEEADRLEISLDLL
EALCAAPSLAGWNGIGFVIQAYQKRCPFVIDHVIDLARRTGHRLMVRLVKGAYWDSEIKRAQVDGLEDYPVYTRKVHTDV
SYIACARRLLAAPDAVYPQFATHNAHTLAAIHELAGPERYTPGQYEFQCLHGMGEPLYEQVVGAAGLDRPCRVYAPVGTH
ETLLAYLVRRLLENGANTSFVNRVADATLPLETLVADPVAAVDAEPMPGEVNPRIPLPPALYGPARRNSAGLDLASEAVL
AQLSDALQRHAYQDWEAVPLLAGPVQAGPRLPVRNPAWHADVVGTVQEASAGDVDQALGWAQAAASAWAATPPAERAAAL
RRAADALEQRTPALLSLLVREAGKTCANAVAEVREAVDFLRFYAAQVETLFGTETGKDAWAPLGPVVCISPWNFPLAIFM
GQVAAALAAGNVVLAKPAEQTPLVAAEAVRILHGAGVPRAAVQLLPGQGETVGARLVGDGRVMGVLFTGSTDVARILQRS
VAGRLDATGRPVPLIAETGGQNAMIVDSSALAEQVVADAVASAFDSAGQRCSALRVLCLQEDVADRVLEMLRGAMAELRI
GRPDQLATDVGPVIDAEARDGILRHVAALRERGRAVHQVPVPPHAGAEGTYVPPTLIELKDLSELEREVFGPVLHVVRYP
RSGLDTLLDRIAGTGYGLTQGLHTRIDETVERVLRRARAGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLLRLV
AQAPGGAARAAIAAMAAPDTGEGHAPAAPAPLQALADWARSAGQGALEAACRQFAQDTPAGSLRTLPGPTGERNQYGVAP
RERILCLADADADRLLQLAAVLAVDGHAVWPSAAATLRATLPATVQERIVLVADWRAPAVAVDAVLHHGTEASLREVCQA
MAARPGPIVGVAGHAPGDAAVPLERLVLERAVSINTAAAGGNASLMTME

Sequences:

>Translated_1249_residues
MNAPHPSLHTRPFSAFAPRPATAAAPLRDAITAACRIPEPEAVAPLLEEARIDGAAARRVHALALRLAGGLRERKGAGGR
AGWVQGLLQEFALSSQEGVALMCLAEALLRIPDSATRDALIRDKIGGGDWESHLGKSPSLFVNAATWGLLLTGRLVATHS
EQGLGAALRRITARGGEPLVRKGVDVAMRMMGEQFVTGETIAQALANARPREAQGFRYSYDMLGEAALTAADAERYLQSY
VDAIHAIGKASAGRGVYEGPGISIKLSALHPRYSRAQHGRVMQELLPRVLGLAELARGYDIGLNIDAEEADRLEISLDLL
EALCAAPSLAGWNGIGFVIQAYQKRCPFVIDHVIDLARRTGHRLMVRLVKGAYWDSEIKRAQVDGLEDYPVYTRKVHTDV
SYIACARRLLAAPDAVYPQFATHNAHTLAAIHELAGPERYTPGQYEFQCLHGMGEPLYEQVVGAAGLDRPCRVYAPVGTH
ETLLAYLVRRLLENGANTSFVNRVADATLPLETLVADPVAAVDAEPMPGEVNPRIPLPPALYGPARRNSAGLDLASEAVL
AQLSDALQRHAYQDWEAVPLLAGPVQAGPRLPVRNPAWHADVVGTVQEASAGDVDQALGWAQAAASAWAATPPAERAAAL
RRAADALEQRTPALLSLLVREAGKTCANAVAEVREAVDFLRFYAAQVETLFGTETGKDAWAPLGPVVCISPWNFPLAIFM
GQVAAALAAGNVVLAKPAEQTPLVAAEAVRILHGAGVPRAAVQLLPGQGETVGARLVGDGRVMGVLFTGSTDVARILQRS
VAGRLDATGRPVPLIAETGGQNAMIVDSSALAEQVVADAVASAFDSAGQRCSALRVLCLQEDVADRVLEMLRGAMAELRI
GRPDQLATDVGPVIDAEARDGILRHVAALRERGRAVHQVPVPPHAGAEGTYVPPTLIELKDLSELEREVFGPVLHVVRYP
RSGLDTLLDRIAGTGYGLTQGLHTRIDETVERVLRRARAGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLLRLV
AQAPGGAARAAIAAMAAPDTGEGHAPAAPAPLQALADWARSAGQGALEAACRQFAQDTPAGSLRTLPGPTGERNQYGVAP
RERILCLADADADRLLQLAAVLAVDGHAVWPSAAATLRATLPATVQERIVLVADWRAPAVAVDAVLHHGTEASLREVCQA
MAARPGPIVGVAGHAPGDAAVPLERLVLERAVSINTAAAGGNASLMTME
>Mature_1249_residues
MNAPHPSLHTRPFSAFAPRPATAAAPLRDAITAACRIPEPEAVAPLLEEARIDGAAARRVHALALRLAGGLRERKGAGGR
AGWVQGLLQEFALSSQEGVALMCLAEALLRIPDSATRDALIRDKIGGGDWESHLGKSPSLFVNAATWGLLLTGRLVATHS
EQGLGAALRRITARGGEPLVRKGVDVAMRMMGEQFVTGETIAQALANARPREAQGFRYSYDMLGEAALTAADAERYLQSY
VDAIHAIGKASAGRGVYEGPGISIKLSALHPRYSRAQHGRVMQELLPRVLGLAELARGYDIGLNIDAEEADRLEISLDLL
EALCAAPSLAGWNGIGFVIQAYQKRCPFVIDHVIDLARRTGHRLMVRLVKGAYWDSEIKRAQVDGLEDYPVYTRKVHTDV
SYIACARRLLAAPDAVYPQFATHNAHTLAAIHELAGPERYTPGQYEFQCLHGMGEPLYEQVVGAAGLDRPCRVYAPVGTH
ETLLAYLVRRLLENGANTSFVNRVADATLPLETLVADPVAAVDAEPMPGEVNPRIPLPPALYGPARRNSAGLDLASEAVL
AQLSDALQRHAYQDWEAVPLLAGPVQAGPRLPVRNPAWHADVVGTVQEASAGDVDQALGWAQAAASAWAATPPAERAAAL
RRAADALEQRTPALLSLLVREAGKTCANAVAEVREAVDFLRFYAAQVETLFGTETGKDAWAPLGPVVCISPWNFPLAIFM
GQVAAALAAGNVVLAKPAEQTPLVAAEAVRILHGAGVPRAAVQLLPGQGETVGARLVGDGRVMGVLFTGSTDVARILQRS
VAGRLDATGRPVPLIAETGGQNAMIVDSSALAEQVVADAVASAFDSAGQRCSALRVLCLQEDVADRVLEMLRGAMAELRI
GRPDQLATDVGPVIDAEARDGILRHVAALRERGRAVHQVPVPPHAGAEGTYVPPTLIELKDLSELEREVFGPVLHVVRYP
RSGLDTLLDRIAGTGYGLTQGLHTRIDETVERVLRRARAGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLLRLV
AQAPGGAARAAIAAMAAPDTGEGHAPAAPAPLQALADWARSAGQGALEAACRQFAQDTPAGSLRTLPGPTGERNQYGVAP
RERILCLADADADRLLQLAAVLAVDGHAVWPSAAATLRATLPATVQERIVLVADWRAPAVAVDAVLHHGTEASLREVCQA
MAARPGPIVGVAGHAPGDAAVPLERLVLERAVSINTAAAGGNASLMTME

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777736, Length=528, Percent_Identity=31.6287878787879, Blast_Score=199, Evalue=1e-50,
Organism=Homo sapiens, GI25777734, Length=528, Percent_Identity=31.6287878787879, Blast_Score=199, Evalue=1e-50,
Organism=Homo sapiens, GI238859541, Length=468, Percent_Identity=32.4786324786325, Blast_Score=190, Evalue=7e-48,
Organism=Homo sapiens, GI21361176, Length=458, Percent_Identity=29.6943231441048, Blast_Score=175, Evalue=2e-43,
Organism=Homo sapiens, GI25777724, Length=469, Percent_Identity=28.997867803838, Blast_Score=167, Evalue=4e-41,
Organism=Homo sapiens, GI25777730, Length=454, Percent_Identity=29.5154185022026, Blast_Score=165, Evalue=2e-40,
Organism=Homo sapiens, GI25777732, Length=455, Percent_Identity=29.4505494505495, Blast_Score=162, Evalue=2e-39,
Organism=Homo sapiens, GI153266822, Length=463, Percent_Identity=27.4298056155508, Blast_Score=161, Evalue=4e-39,
Organism=Homo sapiens, GI188035924, Length=451, Percent_Identity=30.5986696230599, Blast_Score=154, Evalue=7e-37,
Organism=Homo sapiens, GI310128103, Length=451, Percent_Identity=30.5986696230599, Blast_Score=154, Evalue=7e-37,
Organism=Homo sapiens, GI310128093, Length=448, Percent_Identity=30.3571428571429, Blast_Score=153, Evalue=8e-37,
Organism=Homo sapiens, GI21614513, Length=425, Percent_Identity=28.4705882352941, Blast_Score=152, Evalue=2e-36,
Organism=Homo sapiens, GI238814322, Length=425, Percent_Identity=27.2941176470588, Blast_Score=147, Evalue=5e-35,
Organism=Homo sapiens, GI12007648, Length=444, Percent_Identity=28.3783783783784, Blast_Score=147, Evalue=5e-35,
Organism=Homo sapiens, GI25777728, Length=418, Percent_Identity=28.2296650717703, Blast_Score=147, Evalue=9e-35,
Organism=Homo sapiens, GI115387104, Length=445, Percent_Identity=27.8651685393258, Blast_Score=142, Evalue=2e-33,
Organism=Homo sapiens, GI4507229, Length=469, Percent_Identity=27.9317697228145, Blast_Score=138, Evalue=4e-32,
Organism=Homo sapiens, GI25777721, Length=482, Percent_Identity=27.3858921161826, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI25777726, Length=469, Percent_Identity=26.4392324093817, Blast_Score=127, Evalue=1e-28,
Organism=Homo sapiens, GI310128091, Length=393, Percent_Identity=30.7888040712468, Blast_Score=126, Evalue=1e-28,
Organism=Homo sapiens, GI11095441, Length=430, Percent_Identity=26.046511627907, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI25952152, Length=438, Percent_Identity=27.1689497716895, Blast_Score=120, Evalue=1e-26,
Organism=Homo sapiens, GI310128087, Length=270, Percent_Identity=32.5925925925926, Blast_Score=109, Evalue=1e-23,
Organism=Homo sapiens, GI4502043, Length=335, Percent_Identity=28.3582089552239, Blast_Score=101, Evalue=6e-21,
Organism=Homo sapiens, GI238814371, Length=335, Percent_Identity=28.3582089552239, Blast_Score=101, Evalue=6e-21,
Organism=Homo sapiens, GI71773324, Length=335, Percent_Identity=28.3582089552239, Blast_Score=100, Evalue=8e-21,
Organism=Homo sapiens, GI310128089, Length=330, Percent_Identity=29.3939393939394, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI310128101, Length=217, Percent_Identity=31.3364055299539, Blast_Score=89, Evalue=3e-17,
Organism=Homo sapiens, GI310128099, Length=206, Percent_Identity=32.0388349514563, Blast_Score=89, Evalue=3e-17,
Organism=Homo sapiens, GI206597441, Length=441, Percent_Identity=24.9433106575964, Blast_Score=88, Evalue=6e-17,
Organism=Homo sapiens, GI206597439, Length=441, Percent_Identity=24.9433106575964, Blast_Score=88, Evalue=6e-17,
Organism=Homo sapiens, GI22907049, Length=441, Percent_Identity=24.9433106575964, Blast_Score=88, Evalue=6e-17,
Organism=Homo sapiens, GI73695881, Length=334, Percent_Identity=26.9461077844311, Blast_Score=87, Evalue=8e-17,
Organism=Homo sapiens, GI73695879, Length=334, Percent_Identity=26.9461077844311, Blast_Score=87, Evalue=8e-17,
Organism=Homo sapiens, GI310128095, Length=318, Percent_Identity=29.559748427673, Blast_Score=86, Evalue=3e-16,
Organism=Homo sapiens, GI310128097, Length=265, Percent_Identity=30.5660377358491, Blast_Score=80, Evalue=9e-15,
Organism=Homo sapiens, GI4557303, Length=332, Percent_Identity=21.9879518072289, Blast_Score=78, Evalue=7e-14,
Organism=Homo sapiens, GI73466520, Length=332, Percent_Identity=21.9879518072289, Blast_Score=77, Evalue=9e-14,
Organism=Homo sapiens, GI223972651, Length=321, Percent_Identity=28.9719626168224, Blast_Score=72, Evalue=3e-12,
Organism=Homo sapiens, GI301500698, Length=282, Percent_Identity=26.5957446808511, Blast_Score=72, Evalue=5e-12,
Organism=Escherichia coli, GI1787250, Length=1254, Percent_Identity=65.5502392344498, Blast_Score=1573, Evalue=0.0,
Organism=Escherichia coli, GI1787715, Length=463, Percent_Identity=33.4773218142549, Blast_Score=172, Evalue=2e-43,
Organism=Escherichia coli, GI87081896, Length=499, Percent_Identity=30.060120240481, Blast_Score=163, Evalue=7e-41,
Organism=Escherichia coli, GI1789015, Length=461, Percent_Identity=30.3687635574837, Blast_Score=162, Evalue=1e-40,
Organism=Escherichia coli, GI1787684, Length=465, Percent_Identity=29.6774193548387, Blast_Score=161, Evalue=3e-40,
Organism=Escherichia coli, GI1786504, Length=461, Percent_Identity=29.5010845986985, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI1787558, Length=427, Percent_Identity=29.5081967213115, Blast_Score=150, Evalue=5e-37,
Organism=Escherichia coli, GI1788042, Length=444, Percent_Identity=31.0810810810811, Blast_Score=148, Evalue=2e-36,
Organism=Escherichia coli, GI87082295, Length=438, Percent_Identity=28.9954337899543, Blast_Score=137, Evalue=4e-33,
Organism=Escherichia coli, GI87081926, Length=408, Percent_Identity=26.7156862745098, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17534447, Length=482, Percent_Identity=30.4979253112033, Blast_Score=172, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI115534176, Length=451, Percent_Identity=32.5942350332594, Blast_Score=168, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI25144435, Length=461, Percent_Identity=30.8026030368764, Blast_Score=168, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI25143874, Length=441, Percent_Identity=30.1587301587302, Blast_Score=157, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI25143876, Length=441, Percent_Identity=30.1587301587302, Blast_Score=157, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI115532534, Length=381, Percent_Identity=32.0209973753281, Blast_Score=155, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17562198, Length=459, Percent_Identity=28.7581699346405, Blast_Score=154, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI32564736, Length=408, Percent_Identity=30.8823529411765, Blast_Score=154, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI133930964, Length=450, Percent_Identity=28.6666666666667, Blast_Score=149, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71995606, Length=442, Percent_Identity=29.4117647058824, Blast_Score=133, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI32564151, Length=431, Percent_Identity=27.6102088167053, Blast_Score=127, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17551164, Length=438, Percent_Identity=27.1689497716895, Blast_Score=126, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI71995613, Length=399, Percent_Identity=28.8220551378446, Blast_Score=122, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17534119, Length=461, Percent_Identity=26.6811279826464, Blast_Score=122, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71986308, Length=431, Percent_Identity=25.9860788863109, Blast_Score=118, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71990744, Length=316, Percent_Identity=28.4810126582279, Blast_Score=99, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI25146391, Length=372, Percent_Identity=25, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI32566756, Length=372, Percent_Identity=25, Blast_Score=97, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI25146394, Length=372, Percent_Identity=25, Blast_Score=97, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17564084, Length=423, Percent_Identity=23.4042553191489, Blast_Score=84, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6320917, Length=454, Percent_Identity=31.7180616740088, Blast_Score=185, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6325196, Length=464, Percent_Identity=30.8189655172414, Blast_Score=183, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6321826, Length=478, Percent_Identity=28.8702928870293, Blast_Score=182, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6324950, Length=457, Percent_Identity=27.7899343544858, Blast_Score=175, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6323821, Length=471, Percent_Identity=30.1486199575372, Blast_Score=171, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6323822, Length=467, Percent_Identity=29.1220556745182, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6319478, Length=468, Percent_Identity=26.9230769230769, Blast_Score=134, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6323757, Length=329, Percent_Identity=26.7477203647416, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24668425, Length=518, Percent_Identity=26.6409266409266, Blast_Score=169, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24668417, Length=518, Percent_Identity=26.6409266409266, Blast_Score=169, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24668413, Length=518, Percent_Identity=26.6409266409266, Blast_Score=169, Evalue=2e-41,
Organism=Drosophila melanogaster, GI20129399, Length=459, Percent_Identity=29.4117647058824, Blast_Score=163, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24650465, Length=456, Percent_Identity=26.9736842105263, Blast_Score=160, Evalue=5e-39,
Organism=Drosophila melanogaster, GI281362580, Length=449, Percent_Identity=27.1714922048998, Blast_Score=157, Evalue=3e-38,
Organism=Drosophila melanogaster, GI62472918, Length=449, Percent_Identity=27.1714922048998, Blast_Score=157, Evalue=3e-38,
Organism=Drosophila melanogaster, GI62472926, Length=449, Percent_Identity=27.1714922048998, Blast_Score=157, Evalue=3e-38,
Organism=Drosophila melanogaster, GI62472936, Length=449, Percent_Identity=27.1714922048998, Blast_Score=157, Evalue=3e-38,
Organism=Drosophila melanogaster, GI21356737, Length=449, Percent_Identity=27.1714922048998, Blast_Score=157, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24585660, Length=468, Percent_Identity=27.5641025641026, Blast_Score=149, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28571806, Length=449, Percent_Identity=28.9532293986637, Blast_Score=146, Evalue=1e-34,
Organism=Drosophila melanogaster, GI28571802, Length=449, Percent_Identity=28.9532293986637, Blast_Score=146, Evalue=1e-34,
Organism=Drosophila melanogaster, GI28571800, Length=449, Percent_Identity=28.9532293986637, Blast_Score=146, Evalue=1e-34,
Organism=Drosophila melanogaster, GI28571798, Length=449, Percent_Identity=28.9532293986637, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI28571796, Length=449, Percent_Identity=28.9532293986637, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI28571794, Length=449, Percent_Identity=28.9532293986637, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24666674, Length=466, Percent_Identity=29.1845493562232, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI28574525, Length=453, Percent_Identity=28.0353200883002, Blast_Score=137, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24638878, Length=430, Percent_Identity=24.1860465116279, Blast_Score=94, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24638876, Length=430, Percent_Identity=24.1860465116279, Blast_Score=94, Evalue=9e-19,
Organism=Drosophila melanogaster, GI281360301, Length=337, Percent_Identity=27.0029673590504, Blast_Score=93, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281360299, Length=337, Percent_Identity=27.0029673590504, Blast_Score=93, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281360297, Length=337, Percent_Identity=27.0029673590504, Blast_Score=93, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281360295, Length=337, Percent_Identity=27.0029673590504, Blast_Score=93, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24586250, Length=337, Percent_Identity=27.0029673590504, Blast_Score=93, Evalue=1e-18,
Organism=Drosophila melanogaster, GI45552499, Length=337, Percent_Identity=26.4094955489614, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281360303, Length=333, Percent_Identity=26.4264264264264, Blast_Score=92, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 131712; Mature: 131712

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPHPSLHTRPFSAFAPRPATAAAPLRDAITAACRIPEPEAVAPLLEEARIDGAAARRV
CCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHH
HALALRLAGGLRERKGAGGRAGWVQGLLQEFALSSQEGVALMCLAEALLRIPDSATRDAL
HHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHH
IRDKIGGGDWESHLGKSPSLFVNAATWGLLLTGRLVATHSEQGLGAALRRITARGGEPLV
HHHCCCCCCHHHHCCCCCCEEEEHHHHHHHHHHHHEEECCCCCHHHHHHHHHHCCCCHHH
RKGVDVAMRMMGEQFVTGETIAQALANARPREAQGFRYSYDMLGEAALTAADAERYLQSY
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHH
VDAIHAIGKASAGRGVYEGPGISIKLSALHPRYSRAQHGRVMQELLPRVLGLAELARGYD
HHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IGLNIDAEEADRLEISLDLLEALCAAPSLAGWNGIGFVIQAYQKRCPFVIDHVIDLARRT
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
GHRLMVRLVKGAYWDSEIKRAQVDGLEDYPVYTRKVHTDVSYIACARRLLAAPDAVYPQF
HHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHCHHHHHHHHHHHHHCCCCCCCCH
ATHNAHTLAAIHELAGPERYTPGQYEFQCLHGMGEPLYEQVVGAAGLDRPCRVYAPVGTH
HCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEECCCCH
ETLLAYLVRRLLENGANTSFVNRVADATLPLETLVADPVAAVDAEPMPGEVNPRIPLPPA
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHCCCHHHCCCCCCCCCCCCCCCCCCC
LYGPARRNSAGLDLASEAVLAQLSDALQRHAYQDWEAVPLLAGPVQAGPRLPVRNPAWHA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCH
DVVGTVQEASAGDVDQALGWAQAAASAWAATPPAERAAALRRAADALEQRTPALLSLLVR
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAGKTCANAVAEVREAVDFLRFYAAQVETLFGTETGKDAWAPLGPVVCISPWNFPLAIFM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCHHHHHH
GQVAAALAAGNVVLAKPAEQTPLVAAEAVRILHGAGVPRAAVQLLPGQGETVGARLVGDG
HHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCEECEEEEECC
RVMGVLFTGSTDVARILQRSVAGRLDATGRPVPLIAETGGQNAMIVDSSALAEQVVADAV
EEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHHHH
ASAFDSAGQRCSALRVLCLQEDVADRVLEMLRGAMAELRIGRPDQLATDVGPVIDAEARD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHH
GILRHVAALRERGRAVHQVPVPPHAGAEGTYVPPTLIELKDLSELEREVFGPVLHVVRYP
HHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
RSGLDTLLDRIAGTGYGLTQGLHTRIDETVERVLRRARAGNLYVNRNMVGAVVGVQPFGG
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCC
EGLSGTGPKAGGPLYLLRLVAQAPGGAARAAIAAMAAPDTGEGHAPAAPAPLQALADWAR
CCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
SAGQGALEAACRQFAQDTPAGSLRTLPGPTGERNQYGVAPRERILCLADADADRLLQLAA
HCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHEEEEECCCHHHHHHHHH
VLAVDGHAVWPSAAATLRATLPATVQERIVLVADWRAPAVAVDAVLHHGTEASLREVCQA
HHHCCCCCCCCCHHHHHHHHCCCCHHCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHH
MAARPGPIVGVAGHAPGDAAVPLERLVLERAVSINTAAAGGNASLMTME
HHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MNAPHPSLHTRPFSAFAPRPATAAAPLRDAITAACRIPEPEAVAPLLEEARIDGAAARRV
CCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHH
HALALRLAGGLRERKGAGGRAGWVQGLLQEFALSSQEGVALMCLAEALLRIPDSATRDAL
HHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHH
IRDKIGGGDWESHLGKSPSLFVNAATWGLLLTGRLVATHSEQGLGAALRRITARGGEPLV
HHHCCCCCCHHHHCCCCCCEEEEHHHHHHHHHHHHEEECCCCCHHHHHHHHHHCCCCHHH
RKGVDVAMRMMGEQFVTGETIAQALANARPREAQGFRYSYDMLGEAALTAADAERYLQSY
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHH
VDAIHAIGKASAGRGVYEGPGISIKLSALHPRYSRAQHGRVMQELLPRVLGLAELARGYD
HHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IGLNIDAEEADRLEISLDLLEALCAAPSLAGWNGIGFVIQAYQKRCPFVIDHVIDLARRT
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
GHRLMVRLVKGAYWDSEIKRAQVDGLEDYPVYTRKVHTDVSYIACARRLLAAPDAVYPQF
HHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHCHHHHHHHHHHHHHCCCCCCCCH
ATHNAHTLAAIHELAGPERYTPGQYEFQCLHGMGEPLYEQVVGAAGLDRPCRVYAPVGTH
HCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEECCCCH
ETLLAYLVRRLLENGANTSFVNRVADATLPLETLVADPVAAVDAEPMPGEVNPRIPLPPA
HHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHCCCHHHCCCCCCCCCCCCCCCCCCC
LYGPARRNSAGLDLASEAVLAQLSDALQRHAYQDWEAVPLLAGPVQAGPRLPVRNPAWHA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCH
DVVGTVQEASAGDVDQALGWAQAAASAWAATPPAERAAALRRAADALEQRTPALLSLLVR
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAGKTCANAVAEVREAVDFLRFYAAQVETLFGTETGKDAWAPLGPVVCISPWNFPLAIFM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCHHHHHH
GQVAAALAAGNVVLAKPAEQTPLVAAEAVRILHGAGVPRAAVQLLPGQGETVGARLVGDG
HHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCEECEEEEECC
RVMGVLFTGSTDVARILQRSVAGRLDATGRPVPLIAETGGQNAMIVDSSALAEQVVADAV
EEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHHHH
ASAFDSAGQRCSALRVLCLQEDVADRVLEMLRGAMAELRIGRPDQLATDVGPVIDAEARD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHH
GILRHVAALRERGRAVHQVPVPPHAGAEGTYVPPTLIELKDLSELEREVFGPVLHVVRYP
HHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
RSGLDTLLDRIAGTGYGLTQGLHTRIDETVERVLRRARAGNLYVNRNMVGAVVGVQPFGG
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCC
EGLSGTGPKAGGPLYLLRLVAQAPGGAARAAIAAMAAPDTGEGHAPAAPAPLQALADWAR
CCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
SAGQGALEAACRQFAQDTPAGSLRTLPGPTGERNQYGVAPRERILCLADADADRLLQLAA
HCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHEEEEECCCHHHHHHHHH
VLAVDGHAVWPSAAATLRATLPATVQERIVLVADWRAPAVAVDAVLHHGTEASLREVCQA
HHHCCCCCCCCCHHHHHHHHCCCCHHCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHH
MAARPGPIVGVAGHAPGDAAVPLERLVLERAVSINTAAAGGNASLMTME
HHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]