Click here to switch to the map view.

The map label for this gene is qmcA [H]

Identifier: 120611917

GI number: 120611917

Start: 3603569

End: 3604483

Strand: Direct

Name: qmcA [H]

Synonym: Aave_3259

Alternate gene names: 120611917

Gene position: 3603569-3604483 (Clockwise)

Preceding gene: 120611916

Following gene: 120611918

Centisome position: 67.32

GC content: 67.65

Gene sequence:

>915_bases
ATGGAAATCGCCCTCATCCTCTTCGTCATCGCCGGCATCTTCGTCGCCCGCTCCATCAAGGTCGTGCCCCAGCAGAACGC
CTGGGTCAAGGAGCGGCTGGGCAAGTACGCCGGCACGCTCACGCCCGGCCTCAACTTCCTGGTGCCCTTCATCGACCGGG
TCGCCTACAAGCACAGCCTCAAGGAAATCCCGCTGGATGTCCCCAGCCAGGTCTGCATCACGCGCGACAACACCCAGCTG
CAGGTGGACGGCATCCTCTACTTCCAGGTCACCGACCCCATGCGCGCCAGCTACGGATCGAGCAACTACATCATGGCCGT
CACGCAGCTCGCGCAGACCTCCCTGCGCAGCGTGATCGGCCGGCTGGAACTCGACAAGACGTTCGAGGAACGCGACATGA
TCAACGCCCAGGTCGTGGCCGCCATCGACGAGGCCGCCCTCAACTGGGGCGTGAAGGTGCTGCGCTACGAGATCAAGGAC
CTGACCCCGCCCGCCGAAATCCTGCGCGCCATGCAGCAGCAGATCACCGCCGAACGCGAGAAGCGCGCCCTCATCGCCGC
ATCGGAGGGCCGCCGCCAGGAGCAGATCAACATCGCCACCGGCGAGCGCGAGGCCTTCATCGCCCGCTCCGAGGGGGAAA
AGCAGGCGCAGATCAACAACGCCCAGGGCGAGGCCGCCTCCATCACCGCCGTGGCCGAGGCCACCGCCCAGGCCATCGAG
CGCGTGGCCGCCGCCATCCGCCAGCCGGGCGGCGAACAGGCCGTGCAGCTCAAGGTGGCCGAGCGCGCCGTGGACGCCTA
CAGCCGCGTGGCCGCGGACGCCACCACCACCCTGGTCGTGCCCAGCAACATGACCGAGGTTTCCACCCTCATCGCCTCCG
CCATGAAGATGGTCCAGGGCACGCAGCGGCCCTGA

Upstream 100 bases:

>100_bases
GCGCTGCCGCCCCCTGTGCTTTTTTCCCTTTCGCCTGCGCCCCGGCGCAGGGTTCCTTCAACCTCCTTCCCGGCCTTGCT
CCGGGGCTGCAAAGGACTCC

Downstream 100 bases:

>100_bases
ACGCGGAGCACGGACCGCGGCGCCAGATGCCACCACCGGCCGCTCGAAAAAATTCCTGCGCCAGTTCGCGGGGAGCCGCC
GGAATCACTGCTATACTTGC

Product: SPFH domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MEIALILFVIAGIFVARSIKVVPQQNAWVKERLGKYAGTLTPGLNFLVPFIDRVAYKHSLKEIPLDVPSQVCITRDNTQL
QVDGILYFQVTDPMRASYGSSNYIMAVTQLAQTSLRSVIGRLELDKTFEERDMINAQVVAAIDEAALNWGVKVLRYEIKD
LTPPAEILRAMQQQITAEREKRALIAASEGRRQEQINIATGEREAFIARSEGEKQAQINNAQGEAASITAVAEATAQAIE
RVAAAIRQPGGEQAVQLKVAERAVDAYSRVAADATTTLVVPSNMTEVSTLIASAMKMVQGTQRP

Sequences:

>Translated_304_residues
MEIALILFVIAGIFVARSIKVVPQQNAWVKERLGKYAGTLTPGLNFLVPFIDRVAYKHSLKEIPLDVPSQVCITRDNTQL
QVDGILYFQVTDPMRASYGSSNYIMAVTQLAQTSLRSVIGRLELDKTFEERDMINAQVVAAIDEAALNWGVKVLRYEIKD
LTPPAEILRAMQQQITAEREKRALIAASEGRRQEQINIATGEREAFIARSEGEKQAQINNAQGEAASITAVAEATAQAIE
RVAAAIRQPGGEQAVQLKVAERAVDAYSRVAADATTTLVVPSNMTEVSTLIASAMKMVQGTQRP
>Mature_304_residues
MEIALILFVIAGIFVARSIKVVPQQNAWVKERLGKYAGTLTPGLNFLVPFIDRVAYKHSLKEIPLDVPSQVCITRDNTQL
QVDGILYFQVTDPMRASYGSSNYIMAVTQLAQTSLRSVIGRLELDKTFEERDMINAQVVAAIDEAALNWGVKVLRYEIKD
LTPPAEILRAMQQQITAEREKRALIAASEGRRQEQINIATGEREAFIARSEGEKQAQINNAQGEAASITAVAEATAQAIE
RVAAAIRQPGGEQAVQLKVAERAVDAYSRVAADATTTLVVPSNMTEVSTLIASAMKMVQGTQRP

Specific function: Unknown

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family [H]

Homologues:

Organism=Homo sapiens, GI7305503, Length=274, Percent_Identity=50.3649635036496, Blast_Score=264, Evalue=6e-71,
Organism=Homo sapiens, GI38016911, Length=212, Percent_Identity=32.0754716981132, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI21686995, Length=188, Percent_Identity=31.9148936170213, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI221316744, Length=188, Percent_Identity=31.9148936170213, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI7657615, Length=183, Percent_Identity=26.2295081967213, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786697, Length=288, Percent_Identity=39.5833333333333, Blast_Score=211, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI32564147, Length=280, Percent_Identity=45, Blast_Score=256, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17569493, Length=212, Percent_Identity=33.0188679245283, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI193209764, Length=212, Percent_Identity=33.0188679245283, Blast_Score=110, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17569497, Length=189, Percent_Identity=34.3915343915344, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI71989948, Length=155, Percent_Identity=36.1290322580645, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71989955, Length=156, Percent_Identity=35.8974358974359, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17569499, Length=152, Percent_Identity=34.8684210526316, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71987612, Length=165, Percent_Identity=32.1212121212121, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25153583, Length=165, Percent_Identity=32.1212121212121, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17570459, Length=190, Percent_Identity=33.1578947368421, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17570161, Length=194, Percent_Identity=31.9587628865979, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI193210507, Length=194, Percent_Identity=31.9587628865979, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71987621, Length=165, Percent_Identity=32.1212121212121, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI32566490, Length=152, Percent_Identity=30.9210526315789, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71989963, Length=119, Percent_Identity=34.453781512605, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI45550506, Length=277, Percent_Identity=45.4873646209386, Blast_Score=247, Evalue=7e-66,
Organism=Drosophila melanogaster, GI45556022, Length=165, Percent_Identity=33.9393939393939, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI18860517, Length=202, Percent_Identity=33.6633663366337, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281365664, Length=170, Percent_Identity=32.3529411764706, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI62484448, Length=170, Percent_Identity=32.3529411764706, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24657857, Length=170, Percent_Identity=32.3529411764706, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI62484274, Length=170, Percent_Identity=32.3529411764706, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28573263, Length=196, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281361631, Length=222, Percent_Identity=24.7747747747748, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI281361633, Length=222, Percent_Identity=24.7747747747748, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356845, Length=159, Percent_Identity=26.4150943396226, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR018080
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 33269; Mature: 33269

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIALILFVIAGIFVARSIKVVPQQNAWVKERLGKYAGTLTPGLNFLVPFIDRVAYKHSL
CHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
KEIPLDVPSQVCITRDNTQLQVDGILYFQVTDPMRASYGSSNYIMAVTQLAQTSLRSVIG
HHCCCCCCCCEEEECCCCEEEEEEEEEEEECCCHHHCCCCCCHHHHHHHHHHHHHHHHHH
RLELDKTFEERDMINAQVVAAIDEAALNWGVKVLRYEIKDLTPPAEILRAMQQQITAERE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
KRALIAASEGRRQEQINIATGEREAFIARSEGEKQAQINNAQGEAASITAVAEATAQAIE
HHEEEEECCCCCCCEEEEECCCCCEEEECCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHH
RVAAAIRQPGGEQAVQLKVAERAVDAYSRVAADATTTLVVPSNMTEVSTLIASAMKMVQG
HHHHHHHCCCCCHHEEHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHC
TQRP
CCCC
>Mature Secondary Structure
MEIALILFVIAGIFVARSIKVVPQQNAWVKERLGKYAGTLTPGLNFLVPFIDRVAYKHSL
CHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
KEIPLDVPSQVCITRDNTQLQVDGILYFQVTDPMRASYGSSNYIMAVTQLAQTSLRSVIG
HHCCCCCCCCEEEECCCCEEEEEEEEEEEECCCHHHCCCCCCHHHHHHHHHHHHHHHHHH
RLELDKTFEERDMINAQVVAAIDEAALNWGVKVLRYEIKDLTPPAEILRAMQQQITAERE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
KRALIAASEGRRQEQINIATGEREAFIARSEGEKQAQINNAQGEAASITAVAEATAQAIE
HHEEEEECCCCCCCEEEEECCCCCEEEECCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHH
RVAAAIRQPGGEQAVQLKVAERAVDAYSRVAADATTTLVVPSNMTEVSTLIASAMKMVQG
HHHHHHHCCCCCHHEEHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHC
TQRP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]