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The map label for this gene is codA [H]

Identifier: 120611879

GI number: 120611879

Start: 3551794

End: 3553071

Strand: Direct

Name: codA [H]

Synonym: Aave_3221

Alternate gene names: 120611879

Gene position: 3551794-3553071 (Clockwise)

Preceding gene: 120611878

Following gene: 120611881

Centisome position: 66.35

GC content: 72.3

Gene sequence:

>1278_bases
ATGCTCGACCTGCTGATCCACGACGCCACCCTGCCCGACGGCCGCACCTGCATGTCGGTGGCGGTGCAGGACGGCCGCAT
CGCCGAGGTCACCGAAGGGCTGCGCGCGCCCGCGCACGAAACGGTGGACGCCGCCGGCATGCTGCTGAGCCCGCCGTTCG
TGGACGCGCATTTCCACCTCGATGCCGCGCTCTCCTACGGCCTGCCGCGCGTGAACGCCAGCGGCACGCTGCTCGAAGGC
ATCGCGCTCTGGGGCGAACTCAAGCCGCTGCTCACGCAGGAGGCCATCGTGGAGCGCGCCCTGGCGTACTGCGACTGGGC
CGTGGCGCGCGGGCTGCTGGCCATCCGCAGCCACGTGGACACCAGCGACCCGGGCCTGCTGCCCGTGGAGGCATTGCTGG
AAGTGAAGCGCCGCGTGGCCCCCTACCTCGACCTGCAGCTGGTGGCCTTCCCGCAGGATGGCGTGTTGCGCACACCCGGC
GGCCTCGAGAACCTGCGCCGCGCGCTGGACCTGGGCGTGGACGTGGTCGGCGGCATTCCCCACTTCGAGCGCACCATGGC
GCAGGGCGCCGAGAGCGTGCGCCTGCTGTGCGAGCTTGCCGCCGAGCGCGGCCTGCGCGTGGACATGCACTGCGACGAGA
GCGACGACCCGCTGTCGCGCCACGTGGAGACCCTGGCGCATGAAACACACCGCCTGGGCCTGCACGGCCGCGCGACCGGA
TCGCACCTCACGTCCATGCACAGCATGGACAACTACTACGTGAGCAAGCTGATCCCGCTGATGGCCGAGGCGCAGCTGGG
CGTGGTGGCGAATCCGCTCATCAACATCACCCTGCAGGGCCGGCACGACACCTACCCCAGGCGCCGCGGCATGACGCGCG
TGCCCGAGCTGCTCGCGGCCGGGCTGACGGTGGCCTTCGGCCACGATTGCGTGATGGACCCGTGGTACGGCGGCGGCAGC
GCCGACATGCTGGAGGCCGCGCACATGGGCCTGCACGTGGCGCAGATGACCGGGCAGGAGGCGATGCGGCAGTGCTTCGA
CGCCGTGACCGGCAACCCCGCCCGCCTGCTGGGCCTGGAGGGCTATGGGCTCGCCCCGGGCTGCCACGCGGATTTCGTGC
TGCTGCATGCGCGCACGCCTGCGGAGGCCATCCGCCTGCGCGCCACGCGACTGGGCGTCTGGCGGCGCGGACGCCGGTTG
GCGGCCAGCCCCGTGCCCACGGCCACGCTGTCGCTGCCGGGCCGGCCCGCGCAGGTGGACTTCCTGCACAGTCGCTGA

Upstream 100 bases:

>100_bases
TGACCGCGACGCGCGCACGGGCGGCTGGCCCAGAATATGCAATCCGGCAGGCATCCGTCCTGCCCCTTCGATCACACCCC
ACCCACGATCCGGTGCCCCC

Downstream 100 bases:

>100_bases
CCGGAGGCGCGCCCGGCCCCGGGTGCCGGCCCGCCGGTTATCCCCGCCATCCGGCCTGCCGCAGGCAATCCGTGTAGTGC
GCCAGCAGGGCCCCGTCCGC

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MLDLLIHDATLPDGRTCMSVAVQDGRIAEVTEGLRAPAHETVDAAGMLLSPPFVDAHFHLDAALSYGLPRVNASGTLLEG
IALWGELKPLLTQEAIVERALAYCDWAVARGLLAIRSHVDTSDPGLLPVEALLEVKRRVAPYLDLQLVAFPQDGVLRTPG
GLENLRRALDLGVDVVGGIPHFERTMAQGAESVRLLCELAAERGLRVDMHCDESDDPLSRHVETLAHETHRLGLHGRATG
SHLTSMHSMDNYYVSKLIPLMAEAQLGVVANPLINITLQGRHDTYPRRRGMTRVPELLAAGLTVAFGHDCVMDPWYGGGS
ADMLEAAHMGLHVAQMTGQEAMRQCFDAVTGNPARLLGLEGYGLAPGCHADFVLLHARTPAEAIRLRATRLGVWRRGRRL
AASPVPTATLSLPGRPAQVDFLHSR

Sequences:

>Translated_425_residues
MLDLLIHDATLPDGRTCMSVAVQDGRIAEVTEGLRAPAHETVDAAGMLLSPPFVDAHFHLDAALSYGLPRVNASGTLLEG
IALWGELKPLLTQEAIVERALAYCDWAVARGLLAIRSHVDTSDPGLLPVEALLEVKRRVAPYLDLQLVAFPQDGVLRTPG
GLENLRRALDLGVDVVGGIPHFERTMAQGAESVRLLCELAAERGLRVDMHCDESDDPLSRHVETLAHETHRLGLHGRATG
SHLTSMHSMDNYYVSKLIPLMAEAQLGVVANPLINITLQGRHDTYPRRRGMTRVPELLAAGLTVAFGHDCVMDPWYGGGS
ADMLEAAHMGLHVAQMTGQEAMRQCFDAVTGNPARLLGLEGYGLAPGCHADFVLLHARTPAEAIRLRATRLGVWRRGRRL
AASPVPTATLSLPGRPAQVDFLHSR
>Mature_425_residues
MLDLLIHDATLPDGRTCMSVAVQDGRIAEVTEGLRAPAHETVDAAGMLLSPPFVDAHFHLDAALSYGLPRVNASGTLLEG
IALWGELKPLLTQEAIVERALAYCDWAVARGLLAIRSHVDTSDPGLLPVEALLEVKRRVAPYLDLQLVAFPQDGVLRTPG
GLENLRRALDLGVDVVGGIPHFERTMAQGAESVRLLCELAAERGLRVDMHCDESDDPLSRHVETLAHETHRLGLHGRATG
SHLTSMHSMDNYYVSKLIPLMAEAQLGVVANPLINITLQGRHDTYPRRRGMTRVPELLAAGLTVAFGHDCVMDPWYGGGS
ADMLEAAHMGLHVAQMTGQEAMRQCFDAVTGNPARLLGLEGYGLAPGCHADFVLLHARTPAEAIRLRATRLGVWRRGRRL
AASPVPTATLSLPGRPAQVDFLHSR

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=419, Percent_Identity=44.1527446300716, Blast_Score=352, Evalue=2e-98,
Organism=Escherichia coli, GI1786517, Length=398, Percent_Identity=26.8844221105528, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 46015; Mature: 46015

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01137 TATD_1 ; PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLLIHDATLPDGRTCMSVAVQDGRIAEVTEGLRAPAHETVDAAGMLLSPPFVDAHFHL
CCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHCCCEECCCCCCCCEEH
DAALSYGLPRVNASGTLLEGIALWGELKPLLTQEAIVERALAYCDWAVARGLLAIRSHVD
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TSDPGLLPVEALLEVKRRVAPYLDLQLVAFPQDGVLRTPGGLENLRRALDLGVDVVGGIP
CCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCEECCCCHHHHHHHHHCCCHHCCCCC
HFERTMAQGAESVRLLCELAAERGLRVDMHCDESDDPLSRHVETLAHETHRLGLHGRATG
HHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
SHLTSMHSMDNYYVSKLIPLMAEAQLGVVANPLINITLQGRHDTYPRRRGMTRVPELLAA
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEECCCCCCCHHHCCCHHHHHHHHC
GLTVAFGHDCVMDPWYGGGSADMLEAAHMGLHVAQMTGQEAMRQCFDAVTGNPARLLGLE
CCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
GYGLAPGCHADFVLLHARTPAEAIRLRATRLGVWRRGRRLAASPVPTATLSLPGRPAQVD
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCEEC
FLHSR
CCCCC
>Mature Secondary Structure
MLDLLIHDATLPDGRTCMSVAVQDGRIAEVTEGLRAPAHETVDAAGMLLSPPFVDAHFHL
CCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHCCCEECCCCCCCCEEH
DAALSYGLPRVNASGTLLEGIALWGELKPLLTQEAIVERALAYCDWAVARGLLAIRSHVD
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TSDPGLLPVEALLEVKRRVAPYLDLQLVAFPQDGVLRTPGGLENLRRALDLGVDVVGGIP
CCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCEECCCCHHHHHHHHHCCCHHCCCCC
HFERTMAQGAESVRLLCELAAERGLRVDMHCDESDDPLSRHVETLAHETHRLGLHGRATG
HHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
SHLTSMHSMDNYYVSKLIPLMAEAQLGVVANPLINITLQGRHDTYPRRRGMTRVPELLAA
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEECCCCCCCHHHCCCHHHHHHHHC
GLTVAFGHDCVMDPWYGGGSADMLEAAHMGLHVAQMTGQEAMRQCFDAVTGNPARLLGLE
CCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
GYGLAPGCHADFVLLHARTPAEAIRLRATRLGVWRRGRRLAASPVPTATLSLPGRPAQVD
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCEEC
FLHSR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]