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The map label for this gene is blh [H]

Identifier: 120611863

GI number: 120611863

Start: 3533988

End: 3534860

Strand: Reverse

Name: blh [H]

Synonym: Aave_3205

Alternate gene names: 120611863

Gene position: 3534860-3533988 (Counterclockwise)

Preceding gene: 120611865

Following gene: 120611861

Centisome position: 66.04

GC content: 70.22

Gene sequence:

>873_bases
ATGCCCCTTTCCGTCCAGCATTTTTTCGACAGCGCCACCTCCACGTTCTCGTACGTGGTGGACGACGGCGCCGGCCATTG
CGCGGTCATCGATCCCGTCATGGGGTTCGACCAGAAGGCAGGGCGCACCGACCCCGGGCCCGCCGAGGCCCTGGCCGCCC
ACATCGCGGCCAAGGGGTTGCGGGTGGACTGGCTGCTCGAAACCCACGCCCATGCGGACCATCTCTCGGCGGCGCCCTGG
CTCCAGAAGCGCTTCGGCGGGCTGGTGGGCATCGGCGCCGGAATCACGCAGGTCCAGCGGGAATTCCGCGGCATCTTCAA
CGCGACCGACCTGCCCACCGACGGCTCGCAGTTCGGCCACCTGTTCGCCGATGGCGAGACGTTTTCCATCGGGCGCCTGC
AGGCCGCCGCCCTGCACGTGCCCGGCCACACCCCCGCCGACGTCGCCTACCGGATCACCGATCCCGCCGCGGGGCCCGAT
GCGGTCTTCGTGGGGGATACGCTGTTCATGCCCGACGTCGGCACCGCGCGCTGCGACTTTCCCGGCGGCGATGCCCGCAC
GCTGTTCCAGTCGGTGCGGCGCATCCTGGCGCTGCCGGCCGAGACGCTGCTCTATCTCTGCCACGACTATCCGCCCGCGG
GGCGGCAGGCCCAGTGCCGCACGACCGTCGCGCGGCAGCGGGCATCGAACATCCATGTGCGCGACGGCATCGCCGCGCAT
GACTTCGTCGCGATGCGCACCGAGCGCGATGCGACGCTGAACCTTCCGGCGCTCATGCTGCCCGCGGTCCAGGTGAACAT
CCGGGCGGGCCATATGCCCCCCCCCCGAAGCGAACGGCACGGCCTACCTGAAGATCCGGTCAACCTGCTCTGA

Upstream 100 bases:

>100_bases
TTCCGGCAGGGGAGATGGGGTGTGCATGGAGTCTCCGGATGTTTTATTGAATGAAATATCTTTCATTGTATAAAATATTG
CTTCCCAACGAGGAAGCGCC

Downstream 100 bases:

>100_bases
TCCACCCGGCTGCGGGGCGGCCGCCGCGCTGTCCCGGGCGCGGCGCACGCGCGCCGGTGCTCCTAGCGCTTGCGTCCGCC
GAACACGCTGCCCAGCACCC

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MPLSVQHFFDSATSTFSYVVDDGAGHCAVIDPVMGFDQKAGRTDPGPAEALAAHIAAKGLRVDWLLETHAHADHLSAAPW
LQKRFGGLVGIGAGITQVQREFRGIFNATDLPTDGSQFGHLFADGETFSIGRLQAAALHVPGHTPADVAYRITDPAAGPD
AVFVGDTLFMPDVGTARCDFPGGDARTLFQSVRRILALPAETLLYLCHDYPPAGRQAQCRTTVARQRASNIHVRDGIAAH
DFVAMRTERDATLNLPALMLPAVQVNIRAGHMPPPRSERHGLPEDPVNLL

Sequences:

>Translated_290_residues
MPLSVQHFFDSATSTFSYVVDDGAGHCAVIDPVMGFDQKAGRTDPGPAEALAAHIAAKGLRVDWLLETHAHADHLSAAPW
LQKRFGGLVGIGAGITQVQREFRGIFNATDLPTDGSQFGHLFADGETFSIGRLQAAALHVPGHTPADVAYRITDPAAGPD
AVFVGDTLFMPDVGTARCDFPGGDARTLFQSVRRILALPAETLLYLCHDYPPAGRQAQCRTTVARQRASNIHVRDGIAAH
DFVAMRTERDATLNLPALMLPAVQVNIRAGHMPPPRSERHGLPEDPVNLL
>Mature_289_residues
PLSVQHFFDSATSTFSYVVDDGAGHCAVIDPVMGFDQKAGRTDPGPAEALAAHIAAKGLRVDWLLETHAHADHLSAAPWL
QKRFGGLVGIGAGITQVQREFRGIFNATDLPTDGSQFGHLFADGETFSIGRLQAAALHVPGHTPADVAYRITDPAAGPDA
VFVGDTLFMPDVGTARCDFPGGDARTLFQSVRRILALPAETLLYLCHDYPPAGRQAQCRTTVARQRASNIHVRDGIAAHD
FVAMRTERDATLNLPALMLPAVQVNIRAGHMPPPRSERHGLPEDPVNLL

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=277, Percent_Identity=28.158844765343, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI116642887, Length=200, Percent_Identity=28.5, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI21703352, Length=200, Percent_Identity=28.5, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787158, Length=199, Percent_Identity=29.1457286432161, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221330176, Length=253, Percent_Identity=28.0632411067194, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 31147; Mature: 31015

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSVQHFFDSATSTFSYVVDDGAGHCAVIDPVMGFDQKAGRTDPGPAEALAAHIAAKGL
CCCCHHHHHCCHHCEEEEEEECCCCCEEEECCHHCCCCCCCCCCCCHHHHHHHHHHHCCC
RVDWLLETHAHADHLSAAPWLQKRFGGLVGIGAGITQVQREFRGIFNATDLPTDGSQFGH
EEEEEEECCCCHHHCCCCHHHHHHHCCEEEECCCHHHHHHHHHHHCCCCCCCCCCHHCCE
LFADGETFSIGRLQAAALHVPGHTPADVAYRITDPAAGPDAVFVGDTLFMPDVGTARCDF
EEECCCEEECCCEEEEEEECCCCCCCCEEEEEECCCCCCCEEEECCEEECCCCCCCCCCC
PGGDARTLFQSVRRILALPAETLLYLCHDYPPAGRQAQCRTTVARQRASNIHVRDGIAAH
CCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEECCCCCHH
DFVAMRTERDATLNLPALMLPAVQVNIRAGHMPPPRSERHGLPEDPVNLL
HEEEEECCCCCEECCCHHEECEEEEEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PLSVQHFFDSATSTFSYVVDDGAGHCAVIDPVMGFDQKAGRTDPGPAEALAAHIAAKGL
CCCHHHHHCCHHCEEEEEEECCCCCEEEECCHHCCCCCCCCCCCCHHHHHHHHHHHCCC
RVDWLLETHAHADHLSAAPWLQKRFGGLVGIGAGITQVQREFRGIFNATDLPTDGSQFGH
EEEEEEECCCCHHHCCCCHHHHHHHCCEEEECCCHHHHHHHHHHHCCCCCCCCCCHHCCE
LFADGETFSIGRLQAAALHVPGHTPADVAYRITDPAAGPDAVFVGDTLFMPDVGTARCDF
EEECCCEEECCCEEEEEEECCCCCCCCEEEEEECCCCCCCEEEECCEEECCCCCCCCCCC
PGGDARTLFQSVRRILALPAETLLYLCHDYPPAGRQAQCRTTVARQRASNIHVRDGIAAH
CCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEECCCCCHH
DFVAMRTERDATLNLPALMLPAVQVNIRAGHMPPPRSERHGLPEDPVNLL
HEEEEECCCCCEECCCHHEECEEEEEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]