Click here to switch to the map view.

The map label for this gene is yciR [C]

Identifier: 120611288

GI number: 120611288

Start: 2871390

End: 2873621

Strand: Reverse

Name: yciR [C]

Synonym: Aave_2620

Alternate gene names: 120611288

Gene position: 2873621-2871390 (Counterclockwise)

Preceding gene: 120611292

Following gene: 120611283

Centisome position: 53.68

GC content: 67.43

Gene sequence:

>2232_bases
ATGCCCTTCACCAAAGTCCGGTCCCTGCCTGTTCTGGGAACATCCGACGGTCCTGCCGTGGAACGACTCCTGCGCGAGCA
GCAGACGCTACTGGACAGTGCCGGCGTGGGTATCGTGTTCATCCGGCAGCGGCAGGTGGTCCGCTGCAATCCCCGATATG
CGGAAATATTCGGCTACGCCTCCACCCGCGAGGCGATCGGGTTGAGCAGCCAGAGCCTCTACCCCGATTCCGCGGCCTTC
CGCGCCCTCGGGCGGGCGGCCTACCCCACCCTTTCCCTCGGGTTGCCCTACCGCTGCGAGTGCCAGATGCGGCGCAAGAA
CGGCCGCCTCTTCTGGGCCAGCCTCACGGGCCGCCTCATCAATCCGCTGGACACCTCCGAAGGATCGATCTGGATCGTCG
ATGACATCGACGAGCAGCGCCACGCGCAAATCCGGCTGCACGCGGCGATCCGGGAGAAGCAGGCGCTGTTCGACCACGCG
ATGGTGGGCATCGCATTCGTGCGCAACAACCGGCTCACCCGCTGCAACCGGCATTTCGAGCAGATGCTGGGCTACGCGCC
GGGCGAGCTGTCCGAAGGATCGGCCCGCCAGCGGCATTTCAGCGATGCCGACTGGGAGGCCATGGAGTGCCACGGCCACG
GCGAACCGAACGGCACGGGCTTCACCGGCGAGATGGAACTGCTCGCCAAGGACGGCAGCACGGTCGCCTGCGAGGTGCGC
AGCCAGCCGCTGGACCCGCTCTTTCCCGAACAGGGCTGCATCTGCATCGCCATGGACGTGAGCGAGCAGCGCAAGACGCA
GGCGGAACTCGCCCGCATGCACGCCGAACTGGAGCAGCAGGTCCAGGAGCGCACGCGCCAGCTCAGCGAAACCGTCGAGA
GCCTGCACCGCGAGATCAACGACCGCAAGCACGACCAGGAACGCATCTACTGGCTGGCGCACTACGACCCGCTCACCGGC
CTGCCCAACCGCACGCTGCTGGCAGAACGCGCCCAGCACGCGATCCGGGTCGCGCAGGAAAACGGCACGCCCCTGGCGGT
GGTCTTTCTCGATCTGGACCACTTCAAGCATGTGAACGATTCGCTGGGCCACCGGGTCGGCGACGCGCTGCTGGTGGAGA
TCGCCAAGCGCCTGAGGGCCGTGGTGCGCGACCGCGACACGGTTTCCCGGCTGGGCGGCGACGAATTCATCCTGCTGCTG
CCAGGCGCCAATGCCCACGGCGCGGCGCGCGTGGCCACCAAGCTGCAGGAAGCCTCCCGCCAGCCCTACCAGATCGGCCA
CCACGAACTCACCATGGCGCCCTCGATGGGCATCGCCCTCTTCCCGGACGACGGCTGCGATTTCGACACGCTGACGCAGT
CCGCGGACGTGGCCATGTACCGCGCCAAGCTCGACGGACGCAACACCTACCGCTTCTTCACGCCGGAGATGCAGGCGCAG
TCCGTGCGCGCCCTGCTGCTGGAAAACGCGCTGCGGCGGGCCCTGGAGCGCGAGCAGCTCCACCTGCACTACCAGCCCCA
GATCACGATCGCCAGCGGCGAGATCCGCAGCGTGGAGGCCCTGCTGCGCTGGGACCATCCCGAGCTGGGCCCCATCTCGC
CGGCCGAATTCATCCCGATCGCCGAGGACAGCGGCCAGATCCTGCAGATCGGCGAATGGGTGCTCCGCACGGCCCTGGCC
CAGTTGCAGGCCTGGCATGCCATGGGGCTGGAGTGGCTGTCCATGGCAGTCAACCTGTCGGCCCTGCAGTTCCGGCAGCC
ATTGCTGCCGGAACTGGTCAGCCGCATCCTGGAAGAAACCCGCCTGCATCCCCAGCGGCTGGAGCTGGAGCTGACCGAAG
GTGTCGCCGTGGACGATCCGCGGTCGGCCATCGCGACCATGGACCAGCTCCATGCCCGCGGCGTGCGGATGTCGATGGAC
GACTTCGGGACCGGCTATTCGTCCCTGAGCCAGCTCAAGCGCTTCCAGATCTACAAGCTCAAGATCGACCAGTCCTTCGT
GCGCGACCTGGGCGTGGACAGCAACGACCGGGCCATCGTGAGCGCCATCATCCGCATGGCCCAGGCCCTGGGCATGCGCA
CCACCGCCGAGGGCGTGGAAACGGCCGAACAGCTGGAGTACCTGCGGCAGCAGGGTTGCGACGAGGCACAGGGCTACTAC
TTCAGCCGCCCGCAGACCGCGCAGGCCATCACGCCGCTGCTGCAGCAGCGGACGATACGGCCCGAAGGTTGA

Upstream 100 bases:

>100_bases
AGGGCCCCGCTCTTCTGGATTGCCCTGCCCGCCCGGCACCGACTCGCTGCTACACTTTGTTGCTCCCTACCGGCCACCCC
AAGCCGGCGTCCGCCCTGTC

Downstream 100 bases:

>100_bases
GCCGCTTCCCCGCGCGGCAGACCGCCGGCTCCCGCGCCGGGTGGCCTTTTCAACCCGCCCGGGCCGCGTCGGCGAGCTGG
TGGGCGAAATGGCTGGCGCG

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 743; Mature: 742

Protein sequence:

>743_residues
MPFTKVRSLPVLGTSDGPAVERLLREQQTLLDSAGVGIVFIRQRQVVRCNPRYAEIFGYASTREAIGLSSQSLYPDSAAF
RALGRAAYPTLSLGLPYRCECQMRRKNGRLFWASLTGRLINPLDTSEGSIWIVDDIDEQRHAQIRLHAAIREKQALFDHA
MVGIAFVRNNRLTRCNRHFEQMLGYAPGELSEGSARQRHFSDADWEAMECHGHGEPNGTGFTGEMELLAKDGSTVACEVR
SQPLDPLFPEQGCICIAMDVSEQRKTQAELARMHAELEQQVQERTRQLSETVESLHREINDRKHDQERIYWLAHYDPLTG
LPNRTLLAERAQHAIRVAQENGTPLAVVFLDLDHFKHVNDSLGHRVGDALLVEIAKRLRAVVRDRDTVSRLGGDEFILLL
PGANAHGAARVATKLQEASRQPYQIGHHELTMAPSMGIALFPDDGCDFDTLTQSADVAMYRAKLDGRNTYRFFTPEMQAQ
SVRALLLENALRRALEREQLHLHYQPQITIASGEIRSVEALLRWDHPELGPISPAEFIPIAEDSGQILQIGEWVLRTALA
QLQAWHAMGLEWLSMAVNLSALQFRQPLLPELVSRILEETRLHPQRLELELTEGVAVDDPRSAIATMDQLHARGVRMSMD
DFGTGYSSLSQLKRFQIYKLKIDQSFVRDLGVDSNDRAIVSAIIRMAQALGMRTTAEGVETAEQLEYLRQQGCDEAQGYY
FSRPQTAQAITPLLQQRTIRPEG

Sequences:

>Translated_743_residues
MPFTKVRSLPVLGTSDGPAVERLLREQQTLLDSAGVGIVFIRQRQVVRCNPRYAEIFGYASTREAIGLSSQSLYPDSAAF
RALGRAAYPTLSLGLPYRCECQMRRKNGRLFWASLTGRLINPLDTSEGSIWIVDDIDEQRHAQIRLHAAIREKQALFDHA
MVGIAFVRNNRLTRCNRHFEQMLGYAPGELSEGSARQRHFSDADWEAMECHGHGEPNGTGFTGEMELLAKDGSTVACEVR
SQPLDPLFPEQGCICIAMDVSEQRKTQAELARMHAELEQQVQERTRQLSETVESLHREINDRKHDQERIYWLAHYDPLTG
LPNRTLLAERAQHAIRVAQENGTPLAVVFLDLDHFKHVNDSLGHRVGDALLVEIAKRLRAVVRDRDTVSRLGGDEFILLL
PGANAHGAARVATKLQEASRQPYQIGHHELTMAPSMGIALFPDDGCDFDTLTQSADVAMYRAKLDGRNTYRFFTPEMQAQ
SVRALLLENALRRALEREQLHLHYQPQITIASGEIRSVEALLRWDHPELGPISPAEFIPIAEDSGQILQIGEWVLRTALA
QLQAWHAMGLEWLSMAVNLSALQFRQPLLPELVSRILEETRLHPQRLELELTEGVAVDDPRSAIATMDQLHARGVRMSMD
DFGTGYSSLSQLKRFQIYKLKIDQSFVRDLGVDSNDRAIVSAIIRMAQALGMRTTAEGVETAEQLEYLRQQGCDEAQGYY
FSRPQTAQAITPLLQQRTIRPEG
>Mature_742_residues
PFTKVRSLPVLGTSDGPAVERLLREQQTLLDSAGVGIVFIRQRQVVRCNPRYAEIFGYASTREAIGLSSQSLYPDSAAFR
ALGRAAYPTLSLGLPYRCECQMRRKNGRLFWASLTGRLINPLDTSEGSIWIVDDIDEQRHAQIRLHAAIREKQALFDHAM
VGIAFVRNNRLTRCNRHFEQMLGYAPGELSEGSARQRHFSDADWEAMECHGHGEPNGTGFTGEMELLAKDGSTVACEVRS
QPLDPLFPEQGCICIAMDVSEQRKTQAELARMHAELEQQVQERTRQLSETVESLHREINDRKHDQERIYWLAHYDPLTGL
PNRTLLAERAQHAIRVAQENGTPLAVVFLDLDHFKHVNDSLGHRVGDALLVEIAKRLRAVVRDRDTVSRLGGDEFILLLP
GANAHGAARVATKLQEASRQPYQIGHHELTMAPSMGIALFPDDGCDFDTLTQSADVAMYRAKLDGRNTYRFFTPEMQAQS
VRALLLENALRRALEREQLHLHYQPQITIASGEIRSVEALLRWDHPELGPISPAEFIPIAEDSGQILQIGEWVLRTALAQ
LQAWHAMGLEWLSMAVNLSALQFRQPLLPELVSRILEETRLHPQRLELELTEGVAVDDPRSAIATMDQLHARGVRMSMDD
FGTGYSSLSQLKRFQIYKLKIDQSFVRDLGVDSNDRAIVSAIIRMAQALGMRTTAEGVETAEQLEYLRQQGCDEAQGYYF
SRPQTAQAITPLLQQRTIRPEG

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=433, Percent_Identity=39.9538106235566, Blast_Score=321, Evalue=9e-89,
Organism=Escherichia coli, GI87081921, Length=448, Percent_Identity=34.1517857142857, Blast_Score=258, Evalue=9e-70,
Organism=Escherichia coli, GI226510982, Length=466, Percent_Identity=31.7596566523605, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI1790496, Length=246, Percent_Identity=36.5853658536585, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI87081845, Length=239, Percent_Identity=35.9832635983264, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI87081743, Length=233, Percent_Identity=32.618025751073, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1788502, Length=235, Percent_Identity=33.1914893617021, Blast_Score=132, Evalue=9e-32,
Organism=Escherichia coli, GI1786507, Length=287, Percent_Identity=28.9198606271777, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1787055, Length=242, Percent_Identity=33.4710743801653, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87082096, Length=450, Percent_Identity=27.7777777777778, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI87081980, Length=232, Percent_Identity=35.7758620689655, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI1788849, Length=239, Percent_Identity=34.7280334728033, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1788381, Length=646, Percent_Identity=24.4582043343653, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI87082007, Length=166, Percent_Identity=35.5421686746988, Blast_Score=100, Evalue=6e-22,
Organism=Escherichia coli, GI145693134, Length=156, Percent_Identity=37.1794871794872, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI87081977, Length=158, Percent_Identity=31.0126582278481, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787816, Length=172, Percent_Identity=36.6279069767442, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1787802, Length=162, Percent_Identity=32.7160493827161, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87081881, Length=243, Percent_Identity=28.8065843621399, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1786584, Length=153, Percent_Identity=29.4117647058824, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1788956, Length=153, Percent_Identity=35.2941176470588, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1787262, Length=162, Percent_Identity=30.8641975308642, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1787410, Length=228, Percent_Identity=25, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI87081974, Length=102, Percent_Identity=30.3921568627451, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789650, Length=448, Percent_Identity=22.0982142857143, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 83626; Mature: 83495

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFTKVRSLPVLGTSDGPAVERLLREQQTLLDSAGVGIVFIRQRQVVRCNPRYAEIFGYA
CCCCHHCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCEEECCCCHHHHHCCC
STREAIGLSSQSLYPDSAAFRALGRAAYPTLSLGLPYRCECQMRRKNGRLFWASLTGRLI
HHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCEECHHEECCCCCEEEEECCCCCC
NPLDTSEGSIWIVDDIDEQRHAQIRLHAAIREKQALFDHAMVGIAFVRNNRLTRCNRHFE
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QMLGYAPGELSEGSARQRHFSDADWEAMECHGHGEPNGTGFTGEMELLAKDGSTVACEVR
HHHCCCCCCCCCCCHHHHCCCCCCCCEEEECCCCCCCCCCCCCEEEEEECCCCEEEEEEC
SQPLDPLFPEQGCICIAMDVSEQRKTQAELARMHAELEQQVQERTRQLSETVESLHREIN
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRKHDQERIYWLAHYDPLTGLPNRTLLAERAQHAIRVAQENGTPLAVVFLDLDHFKHVND
CCCCCCHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHHHHHH
SLGHRVGDALLVEIAKRLRAVVRDRDTVSRLGGDEFILLLPGANAHGAARVATKLQEASR
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHCC
QPYQIGHHELTMAPSMGIALFPDDGCDFDTLTQSADVAMYRAKLDGRNTYRFFTPEMQAQ
CCCCCCCEEEEECCCCCEEEECCCCCCHHHHHCCCHHHEEEEECCCCCEEEEECCCHHHH
SVRALLLENALRRALEREQLHLHYQPQITIASGEIRSVEALLRWDHPELGPISPAEFIPI
HHHHHHHHHHHHHHHHHHHEEEEECCEEEEECCCHHHHHHHHHCCCCCCCCCCCHHEEEE
AEDSGQILQIGEWVLRTALAQLQAWHAMGLEWLSMAVNLSALQFRQPLLPELVSRILEET
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
RLHPQRLELELTEGVAVDDPRSAIATMDQLHARGVRMSMDDFGTGYSSLSQLKRFQIYKL
CCCHHHEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEHHHCCCCHHHHHHHHHHEEEEE
KIDQSFVRDLGVDSNDRAIVSAIIRMAQALGMRTTAEGVETAEQLEYLRQQGCDEAQGYY
EECHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHCCEE
FSRPQTAQAITPLLQQRTIRPEG
ECCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PFTKVRSLPVLGTSDGPAVERLLREQQTLLDSAGVGIVFIRQRQVVRCNPRYAEIFGYA
CCCHHCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCEEECCCCHHHHHCCC
STREAIGLSSQSLYPDSAAFRALGRAAYPTLSLGLPYRCECQMRRKNGRLFWASLTGRLI
HHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCEECHHEECCCCCEEEEECCCCCC
NPLDTSEGSIWIVDDIDEQRHAQIRLHAAIREKQALFDHAMVGIAFVRNNRLTRCNRHFE
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QMLGYAPGELSEGSARQRHFSDADWEAMECHGHGEPNGTGFTGEMELLAKDGSTVACEVR
HHHCCCCCCCCCCCHHHHCCCCCCCCEEEECCCCCCCCCCCCCEEEEEECCCCEEEEEEC
SQPLDPLFPEQGCICIAMDVSEQRKTQAELARMHAELEQQVQERTRQLSETVESLHREIN
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRKHDQERIYWLAHYDPLTGLPNRTLLAERAQHAIRVAQENGTPLAVVFLDLDHFKHVND
CCCCCCHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHHHHHH
SLGHRVGDALLVEIAKRLRAVVRDRDTVSRLGGDEFILLLPGANAHGAARVATKLQEASR
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHCC
QPYQIGHHELTMAPSMGIALFPDDGCDFDTLTQSADVAMYRAKLDGRNTYRFFTPEMQAQ
CCCCCCCEEEEECCCCCEEEECCCCCCHHHHHCCCHHHEEEEECCCCCEEEEECCCHHHH
SVRALLLENALRRALEREQLHLHYQPQITIASGEIRSVEALLRWDHPELGPISPAEFIPI
HHHHHHHHHHHHHHHHHHHEEEEECCEEEEECCCHHHHHHHHHCCCCCCCCCCCHHEEEE
AEDSGQILQIGEWVLRTALAQLQAWHAMGLEWLSMAVNLSALQFRQPLLPELVSRILEET
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
RLHPQRLELELTEGVAVDDPRSAIATMDQLHARGVRMSMDDFGTGYSSLSQLKRFQIYKL
CCCHHHEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEHHHCCCCHHHHHHHHHHEEEEE
KIDQSFVRDLGVDSNDRAIVSAIIRMAQALGMRTTAEGVETAEQLEYLRQQGCDEAQGYY
EECHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHCCEE
FSRPQTAQAITPLLQQRTIRPEG
ECCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]